beta-thujaplicin has been researched along with Leukemia P388 in 3 studies
beta-thujaplicin: structure
beta-thujaplicin : A monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bistropolone derivatives (4-12) containing differing lengths of linkage between the two tropolone rings were prepared and examined for their antitumor activity in in vitro (KB cell) and in vivo (leukemia P388 in mice) systems." | 3.68 | Synthesis and antitumor activity of tropolone derivatives. 7. Bistropolones containing connecting methylene chains. ( Ando, J; Hashigaki, K; Sakaki, K; Tashiro, T; Tsukagoshi, S; Tsuruo, T; Wataya, Y; Yamato, M, 1992) |
| "Treatment of tropolones with benzaldehyde diethyl acetals gave monotropolone (12) and bistropolone (13) derivatives at the benzylic position, whereas the related 1-ethoxyisochroman and the diethyl acetals of crotonaldehyde and cinnamaldehyde gave only the monotropolone derivatives (5, 10, or 11)." | 1.27 | Synthesis and antitumor activity of tropolone derivatives. ( Hashigaki, K; Kokubu, N; Tashiro, T; Tsuruo, T; Yamato, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamato, M | 2 |
| Ando, J | 1 |
| Sakaki, K | 1 |
| Hashigaki, K | 2 |
| Wataya, Y | 1 |
| Tsukagoshi, S | 1 |
| Tashiro, T | 2 |
| Tsuruo, T | 2 |
| Kokubu, N | 1 |
| Morita, Y | 1 |
| Matsumura, E | 1 |
| Okabe, T | 1 |
| Fukui, T | 1 |
| Shibata, M | 1 |
| Sugiura, M | 1 |
| Ohe, T | 1 |
| Tsujibo, H | 1 |
| Ishida, N | 1 |
| Inamori, Y | 1 |
3 other studies available for beta-thujaplicin and Leukemia P388
| Article | Year |
|---|---|
Synthesis and antitumor activity of tropolone derivatives. 7. Bistropolones containing connecting methylene chains.
Topics: Animals; Antineoplastic Agents; Deoxyribonucleotides; Leukemia P388; Mice; Structure-Activity Relati | 1992 |
Synthesis and antitumor activity of tropolone derivatives.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Division; Cell Line; Cell Survival; Cycloheptanes; D | 1984 |
Biological activity of alpha-thujaplicin, the isomer of hinokitiol.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Leukemia P388; Mice | 2004 |