beta-naphthoflavone has been researched along with Pregnancy in 35 studies
beta-Naphthoflavone: A polyaromatic hydrocarbon inducer of P4501A1 and P4501A2 cytochromes. (Proc Soc Exp Biol Med 1994 Dec:207(3):302-308)
beta-naphthoflavone : An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with phenobarbital, which induces CYP enzymes that detoxify IQ, decreased adducts in maternal liver and possibly placenta, but not in fetal tissues." | 1.31 | DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in fetal tissues of patas monkeys after transplacental exposure. ( Anderson, LM; Grady, JJ; Jones, AB; Josyula, S; Lu, LJ; Nerurkar, PV; Salazar, JJ; Snyderwine, EG, 2000) |
| "Caffeine, 175 mg/kg, was given ip on Days 11 and 12 of gestation." | 1.27 | Alteration of effective exposure of dam and embryo to caffeine and its metabolites by treatment of mice with beta-naphthoflavone. ( O'Flaherty, EJ; Scott, WJ; Shukla, R; York, RG, 1987) |
| " A dosage of eighty mg/kg/d was more effective than 20 mg/kg/d beta-NF in decreasing malformations, suggesting that stimulation of metabolism and caffeine-induced teratogenicity are inversely related." | 1.27 | Reduction of caffeine teratogenicity in mice by inducing maternal drug metabolism with beta-naphthoflavone. ( Randall, JL; Scott, WJ; York, RG, 1985) |
| "Fetal death was induced even when the two compounds were administered at wider intervals." | 1.26 | TCDD embryotoxicity in the mouse may be enhanced by beta-naphthoflavone, another ligand of the Ah-receptor. ( Dencker, L; Hassoun, EM, 1982) |
| "Phenobarbital pretreatment increased the activation of cyclophosphamide to mutagenic metabolites by maternal liver microsomes 10-fold and liver cytochrome P-450 content 1." | 1.26 | Modification of the mutagenicity and teratogenicity of cyclophosphamide in rats with inducers of the cytochromes P-450. ( Hales, BF, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (74.29) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| El-Dairi, R | 1 |
| Huuskonen, P | 1 |
| Pasanen, M | 1 |
| Rysä, J | 1 |
| Wu, Y | 1 |
| Chen, X | 1 |
| Chang, X | 1 |
| Huang, YJ | 1 |
| Bao, S | 1 |
| He, Q | 1 |
| Li, Y | 1 |
| Zheng, J | 1 |
| Duan, T | 1 |
| Wang, K | 1 |
| Couroucli, XI | 1 |
| Liang, YH | 1 |
| Jiang, W | 1 |
| Wang, L | 1 |
| Barrios, R | 1 |
| Yang, P | 1 |
| Moorthy, B | 1 |
| Kahl, GF | 1 |
| Friederici, DE | 1 |
| Bigelow, SW | 1 |
| Okey, AB | 1 |
| Nebert, DW | 2 |
| Rouet, P | 2 |
| Alexandrov, K | 1 |
| Markovits, P | 1 |
| Frayssinet, C | 2 |
| Dansette, PM | 1 |
| Ritter, CL | 3 |
| Malejka-Giganti, D | 4 |
| Hassoun, EM | 1 |
| Dencker, L | 1 |
| Decker, RW | 2 |
| Chiang, JY | 1 |
| DiLella, AG | 1 |
| Steggles, AW | 1 |
| Dansette, P | 1 |
| Shiverick, KT | 5 |
| Ortiz, E | 3 |
| Fuhrman-Lane, C | 3 |
| Crowley, P | 1 |
| Kellis, JT | 1 |
| Vickery, LE | 1 |
| Manchester, DK | 1 |
| Parker, NB | 1 |
| Bowman, CM | 1 |
| Brandt, I | 1 |
| Gustafsson, JA | 1 |
| Rafter, J | 1 |
| Galloway, SM | 1 |
| Perry, PE | 1 |
| Meneses, J | 1 |
| Pedersen, RA | 1 |
| Hales, BF | 1 |
| Anderson, LM | 5 |
| Priest, LJ | 1 |
| Morse, DC | 1 |
| Van Bladeren, PJ | 1 |
| Klasson Wehler, E | 1 |
| Brouwer, A | 1 |
| Sawada, M | 1 |
| Kitamura, R | 1 |
| Norose, T | 1 |
| Kitada, M | 1 |
| Itahashi, K | 1 |
| Kamataki, T | 1 |
| Lupp, A | 1 |
| Lau, K | 1 |
| Trautmann, AK | 1 |
| Krausse, T | 1 |
| Klinger, W | 1 |
| Josyula, S | 1 |
| Lu, LJ | 1 |
| Salazar, JJ | 1 |
| Nerurkar, PV | 1 |
| Jones, AB | 4 |
| Grady, JJ | 1 |
| Snyderwine, EG | 1 |
| Riggs, CW | 2 |
| Guyda, HJ | 1 |
| Miller, MS | 1 |
| Chauhan, DP | 1 |
| Park, SS | 1 |
| Kovatch, RM | 1 |
| Wang, SL | 1 |
| Raizada, MK | 1 |
| York, RG | 2 |
| O'Flaherty, EJ | 1 |
| Scott, WJ | 2 |
| Shukla, R | 1 |
| Swanson, C | 1 |
| Salhab, AS | 1 |
| James, MO | 1 |
| George, JD | 1 |
| Manson, JM | 1 |
| Ryzewski, CN | 1 |
| Polovina, MR | 1 |
| Randall, JL | 1 |
| Namkung, MJ | 1 |
| Porubek, DJ | 1 |
| Nelson, SD | 1 |
| Juchau, MR | 1 |
35 other studies available for beta-naphthoflavone and Pregnancy
| Article | Year |
|---|---|
Aryl hydrocarbon receptor (AhR) agonist β-naphthoflavone regulated gene networks in human primary trophoblasts.
Topics: Basic Helix-Loop-Helix Transcription Factors; beta-Naphthoflavone; Cell Survival; Cells, Cultured; F | 2020 |
Potential involvement of placental AhR in unexplained recurrent spontaneous abortion.
Topics: Abortion, Habitual; Adult; Basic Helix-Loop-Helix Transcription Factors; beta-Naphthoflavone; Biomar | 2016 |
Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants.
Topics: Acute Lung Injury; Animals; Animals, Newborn; beta-Naphthoflavone; Blotting, Western; Bronchopulmona | 2011 |
Ontogenetic expression of regulatory and structural gene products associated with the Ah locus. Comparison of rat, mouse, rabbit and Sigmoden hispedis.
Topics: Animals; Arvicolinae; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome | 1980 |
Metabolism of benzo[a]pyrene by brain microsomes of fetal and adult rats and mice. Induction by 5,6 benzoflavone, comparison with liver and lung microsomal activities.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Brain; Cytochrome P-450 E | 1981 |
Mixed function oxidase in the mammary gland and liver microsomes of lactating rats. Effects of 3-methylcholanthrene and beta-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Fe | 1982 |
TCDD embryotoxicity in the mouse may be enhanced by beta-naphthoflavone, another ligand of the Ah-receptor.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Dioxins; Female; Fetal Death; Flavonoids; Ligands; Mice | 1982 |
Modifications of carcinogen metabolism in hepatic microsomes of suckling young by 3-methylcholanthrene or beta-naphthoflavone administered to lactating rats.
Topics: 2-Acetylaminofluorene; Animal Population Groups; Animals; Animals, Suckling; Benzo(a)pyrene; Benzofl | 1983 |
Effect of inducers and aging on rabbit liver microsomal drug-metabolizing enzymes.
Topics: Aging; Animals; Benzoflavones; beta-Naphthoflavone; Cholesterol; Cholestyramine Resin; Cytochrome b | 1983 |
Ontogeny of benzo(a)pyrene hydroxylase, epoxide hydrolase and glutathione-S transferase in the brain, lung and liver of C57Bl/6 mice.
Topics: Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; be | 1984 |
Effects of beta-naphthoflavone and 3-methylcholanthrene administered to pregnant rats on steroid metabolism in the isolated basal zone of the placenta.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Chromatography, T | 1984 |
Inhibition of human estrogen synthetase (aromatase) by flavones.
Topics: Androstenedione; Aromatase Inhibitors; Benzoflavones; beta-Naphthoflavone; Binding Sites; Binding, C | 1984 |
Maternal smoking increases xenobiotic metabolism in placenta but not umbilical vein endothelium.
Topics: Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Dose-Response Re | 1984 |
Distribution of the carcinogenic tryptophan pyrolysis product Trp-P-1 in control, 9-hydroxyellipticine and beta-naphthoflavone pretreated mice.
Topics: Alkaloids; Animals; Benzoflavones; beta-Naphthoflavone; Carbolines; Ellipticines; Endocrine Glands; | 1983 |
Effects of beta-naphthoflavone administration to pregnant rats on steroid hormone biosynthesis and metabolism in ovarian microsomes.
Topics: Animals; Aromatase; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Estradiol; F | 1983 |
Effects of beta-naphthoflavone administration during midgestation on ovarian steroid metabolism and fetal development.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Estrogens; Female; Fetu | 1983 |
Cultured mouse embryos metabolize benzo[a]pyrene during early gestation: genetic differences detectable by sister chromatid exchange.
Topics: Animals; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzym | 1980 |
Modification of the mutagenicity and teratogenicity of cyclophosphamide in rats with inducers of the cytochromes P-450.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cyclophosphamide; Cytochrome P-450 E | 1981 |
Reduction in the transplacental carcinogenic effect of methylcholanthrene in mice by prior treatment with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; Female; Fetus; Flavonoids; Liver; Lung Neo | 1980 |
beta-Naphthoflavone- and self-induced metabolism of 3,3',4,4'-tetrachlorobiphenyl in hepatic microsomes of the male, pregnant female and foetal rat.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cytochrome P-450 | 1995 |
Metabolic activation of aflatoxin B1 by human placental microsomes.
Topics: Aflatoxin B1; Aminoglutethimide; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P | 1993 |
Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: inducibility of cytochrome P450 dependent monooxygenase functions by beta-naphthoflavone, phenobarbital and dexamethasone.
Topics: Animals; beta-Naphthoflavone; Body Weight; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Ind | 1999 |
DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in fetal tissues of patas monkeys after transplacental exposure.
Topics: Animals; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; Dose-Respons | 2000 |
Long-term (imprinting) effects of transplacental treatment of mice with 3-methylcholanthrene or beta-naphthoflavone on hepatic metabolism of 3-methylcholanthrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Female; Gene Expression | 1991 |
Metabolic effects of growth factors and polycyclic aromatic hydrocarbons on cultured human placental cells of early and late gestation.
Topics: Aminoisobutyric Acids; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; ErbB Receptors; Female; | 1991 |
Differential induction of fetal mouse liver and lung cytochromes P-450 by beta-naphthoflavone and 3-methylcholanthrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme | 1989 |
Modification of transplacental tumorigenesis by 3-methylcholanthrene in mice by genotype at the Ah locus and pretreatment with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Female; Fetal Diseases; Fetus; Flavonoids; Genotype; Li | 1989 |
Effects of beta-naphthoflavone on insulin receptor binding and protein kinase activity in rat liver and placenta.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Female; Flavonoids; Gestational Age; In Vitro Technique | 1988 |
Alteration of effective exposure of dam and embryo to caffeine and its metabolites by treatment of mice with beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Caffeine; Drug Interactions; Embryo, | 1987 |
Differential induction of ethoxyresorufin-O-deethylase in tissues of the rat placenta.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Ear, Inner; Enzyme Induction; | 1986 |
Strain-dependent differences in the metabolism of 3-methylcholanthrene by maternal, placental, and fetal tissues of C57BL/6J and DBA/2J mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Female | 1986 |
Microsomal metabolism of the carcinogen, N-2-fluorenyl-acetamide, by the mammary gland and liver of female rats. II. Glucuronidation of ring- and N-hydroxylated metabolites of N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; beta-Naphthoflavone; Carbon Radioisotopes; Female; Gl | 1985 |
Microsomal metabolism of the carcinogen, N-2-fluorenylacetamide, by the mammary gland and liver of female rats. I. Ring- and N-hydroxylations of N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome b Group; Cytochrome P | 1985 |
Reduction of caffeine teratogenicity in mice by inducing maternal drug metabolism with beta-naphthoflavone.
Topics: Abnormalities, Drug-Induced; Animals; Benzoflavones; beta-Naphthoflavone; Caffeine; Cytochrome P-450 | 1985 |
Regulation of aromatic oxidation of estradiol-17 beta in maternal hepatic, fetal hepatic and placental tissues: comparative effects of a series of inducing agents.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-4 | 1985 |