beta-naphthoflavone has been researched along with Hepatocellular Carcinoma in 17 studies
beta-Naphthoflavone: A polyaromatic hydrocarbon inducer of P4501A1 and P4501A2 cytochromes. (Proc Soc Exp Biol Med 1994 Dec:207(3):302-308)
beta-naphthoflavone : An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human hepatoma HepG2 cells were treated with β-naphthoflavone for 3 days, and intracellular labile and total zinc levels were assessed through flow cytometry and inductively coupled plasma atom emission spectroscopy, respectively." | 1.51 | β-Naphthoflavone, an exogenous ligand of aryl hydrocarbon receptor, disrupts zinc homeostasis in human hepatoma HepG2 cells. ( Ishida, T; Takechi, S, 2019) |
| "When murine hepatoma cell line Hepa-1c1c7 was stably transfected with this construct, established sensor clones secreted SEAP following stimulation with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)." | 1.32 | DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase. ( Hiramatsu, N; Kasai, A; Kitamura, M; Maeda, S; Meng, Y; Takeda, M; Yao, J, 2004) |
| " Transfected cells were dosed with several known inducers of CYP3A4 and the levels of SPAP were measured." | 1.30 | A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. ( Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM, 1999) |
| "Two human hepatoma cell lines, KYN-2 and Mz-Hep-1 were characterized in terms of glucuronidation capacity and inducibility of cytochrome P4501A1/1A2 and several UDP-glucuronosyltransferases (UGTs)." | 1.29 | Inducibility of ethoxyresorufin deethylase and UDP-glucuronosyltransferase activities in two human hepatocarcinoma cell lines KYN-2 and Mz-Hep-1. ( Abid, A; Magdalou, J; Sabolovic, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 10 (58.82) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishida, T | 1 |
| Takechi, S | 1 |
| Lammel, T | 1 |
| Boisseaux, P | 1 |
| Navas, JM | 1 |
| Münzel, PA | 1 |
| Schmohl, S | 1 |
| Buckler, F | 1 |
| Jaehrling, J | 1 |
| Raschko, FT | 1 |
| Köhle, C | 1 |
| Bock, KW | 1 |
| Kasai, A | 1 |
| Hiramatsu, N | 1 |
| Meng, Y | 1 |
| Yao, J | 1 |
| Takeda, M | 1 |
| Maeda, S | 1 |
| Kitamura, M | 1 |
| Elbekai, RH | 1 |
| Korashy, HM | 1 |
| Wills, K | 1 |
| Gharavi, N | 2 |
| El-Kadi, AO | 2 |
| Favreau, LV | 2 |
| Pickett, CB | 3 |
| Rosenberg, DW | 1 |
| Leff, T | 1 |
| Abid, A | 2 |
| Sabolovic, N | 2 |
| Magdalou, J | 2 |
| Wang, H | 1 |
| Griffiths, S | 1 |
| Williamson, G | 1 |
| Moinova, HR | 2 |
| Mulcahy, RT | 2 |
| Burczynski, ME | 1 |
| Lin, HK | 1 |
| Penning, TM | 1 |
| Ogg, MS | 1 |
| Williams, JM | 1 |
| Tarbit, M | 1 |
| Goldfarb, PS | 1 |
| Gray, TJ | 1 |
| Gibson, GG | 1 |
| Rushmore, TH | 1 |
| King, RG | 1 |
| Paulson, KE | 1 |
| Bayney, RM | 1 |
| Morton, MR | 1 |
17 other studies available for beta-naphthoflavone and Hepatocellular Carcinoma
| Article | Year |
|---|---|
β-Naphthoflavone, an exogenous ligand of aryl hydrocarbon receptor, disrupts zinc homeostasis in human hepatoma HepG2 cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cation | 2019 |
Potentiating effect of graphene nanomaterials on aromatic environmental pollutant-induced cytochrome P450 1A expression in the topminnow fish hepatoma cell line PLHC-1.
Topics: Animals; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP1A1; | 2015 |
Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells.
Topics: 5' Flanking Region; Animals; Antioxidants; beta-Naphthoflavone; Caco-2 Cells; Carcinoma, Hepatocellu | 2003 |
DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.
Topics: Alkaline Phosphatase; Animals; Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytoc | 2004 |
Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.
Topics: Benzo(a)pyrene; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cyt | 2004 |
Role of nitric oxide in downregulation of cytochrome P450 1a1 and NADPH: Quinone oxidoreductase 1 by tumor necrosis factor-alpha and lipopolysaccharide.
Topics: Animals; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP1A1; | 2007 |
The rat quinone reductase antioxidant response element. Identification of the nucleotide sequence required for basal and inducible activity and detection of antioxidant response element-binding proteins in hepatoma and non-hepatoma cell lines.
Topics: Animals; Antioxidants; Base Sequence; Benzoflavones; beta-Naphthoflavone; Carcinoma, Hepatocellular; | 1995 |
Regulation of cytochrome P450 in cultured human colonic cells.
Topics: Adenocarcinoma; Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinoma | 1993 |
Inducibility of ethoxyresorufin deethylase and UDP-glucuronosyltransferase activities in two human hepatocarcinoma cell lines KYN-2 and Mz-Hep-1.
Topics: Antibiotics, Antitubercular; Benzoflavones; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytochro | 1996 |
Effect of glucosinolate breakdown products on beta-naphthoflavone-induced expression of human cytochrome P450 1A1 via the Ah receptor in Hep G2 cells.
Topics: beta-Naphthoflavone; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Genes, Reporter; Glucosinol | 1997 |
Expression and inducibility of UDP-glucuronosyltransferases 1-naphthol in human cultured hepatocytes and hepatocarcinoma cell lines.
Topics: beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line; Enzyme Induction; Gene Expression Regulat | 1997 |
An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site.
Topics: Antioxidants; Base Sequence; beta-Naphthoflavone; Binding Sites; Carcinoma, Hepatocellular; Cloning, | 1998 |
Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Benzopyrenes; Benzoquinones; beta | 1999 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofi | 1999 |
Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element.
Topics: Base Sequence; beta-Naphthoflavone; Binding Sites; Carcinoma, Hepatocellular; Cell Nucleus; Dimeriza | 1999 |
Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds.
Topics: Base Sequence; Benzoflavones; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line; Cell Nucleu | 1990 |
Rat liver NAD(P)H: Quinone reductase. Regulation of quinone reductase gene expression by planar aromatic compounds and determination of the exon structure of the quinone reductase structural gene.
Topics: Amino Acid Sequence; Animals; Azo Compounds; Base Sequence; Benzoflavones; beta-Naphthoflavone; Carc | 1989 |