beta-naphthoflavone and Experimental Hepatoma

beta-naphthoflavone has been researched along with Experimental Hepatoma in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19907 (30.43)18.7374
1990's5 (21.74)18.2507
2000's4 (17.39)29.6817
2010's7 (30.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dere, E; Forgacs, AL; Nault, R; Zacharewski, TR1
Dewa, Y; Hayashi, SM; Ichimura, R; Mitsumori, K; Mizukami, S; Shibutani, M; Shimada, Y; Suzuki, T1
Asamoto, M; Doi, Y; Naiki-Ito, A; Shirai, T; Suzuki, S; Takahashi, S; Takeshita, K1
Dewa, Y; Hayashi, H; Imaoka, M; Kemmochi, S; Mitsumori, K; Shibutani, M; Shimamoto, K; Taniai, E1
Hayashi, H; Hayashi, SM; Kuwata, K; Mitsumori, K; Shibutani, M; Shimamoto, K; Suzuki, K1
Hayashi, H; Mitsumori, K; Morita, R; Shibutani, M; Suzuki, K; Taniai, E; Yafune, A1
Hayashi, H; Hayashi, M; Mitsumori, K; Morita, R; Nakamura, D; Shibutani, M; Suzuki, K; Taniai, E; Wakita, A1
Bailey, GS; Givan, SA; Pereira, CB; Tilton, SC; Williams, DE1
Dewa, Y; Jin, M; Mitsumori, K; Muguruma, M; Nishimura, J; Okamura, T; Saegusa, Y; Tasaki, M; Umemura, T1
Favreau, LV; Pickett, CB1
Adamo, D; Bassi, AM; Castell, JV; Donato, MT; Ferro, M; Gómez-Lechón, MJ; Herrero, E; Penco, S1
Perdew, GH; Swanson, HI1
Dutchuk, M; Hendricks, JD; Kelly, JD; Williams, DE1
Gujaeva, EL; Koblyakov, VA; Kondalenko, VF; Ostashkina, NM1
Alexander, D; Bailey, G; Baird, W; Harttig, U; Hendricks, J; Miller, MR; Reddy, AP; Stamm, SC; Weimer, TL1
Bassi, AM; Canuto, R; Ferro, M; Ledda, S; Menini, S; Muzio, G; Penco, S1
Bayney, RM; Favreau, LV; Morton, MR; Pickett, CB1
Bailey, GS; Hendricks, JD; Lee, BC1
Anderson, LM; Jones, AB; Kovatch, RM; Riggs, CW1
Kent, C; Paulson, BK; Porter, TJ1
King, RG; Pickett, CB; Telakowski-Hopkins, CA1
Bassi, AM; Ferro, M; Marinari, UM; Nanni, G1
Bansal, SK; Fox, HW; Gurtoo, HL; Koser, PL; Mulhern, AI; Pavelic, ZP; Sharma, SD1

Other Studies

23 other study(ies) available for beta-naphthoflavone and Experimental Hepatoma

ArticleYear
Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver.
    Toxicology letters, 2013, Oct-23, Volume: 223, Issue:1

    Topics: Animals; beta-Naphthoflavone; Carbazoles; Cell Line, Tumor; Female; Gene Expression; Gene Expression Profiling; Liver; Liver Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon

2013
Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone.
    Toxicology, 2010, Feb-09, Volume: 268, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; beta-Naphthoflavone; Connective Tissue; Cyclooxygenase 2; Glutathione Peroxidase; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2010
2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis is not enhanced by CYP1A inducers, alpha- and beta-naphthoflavone: relationship to intralobular distribution of CYP1A expression.
    Toxicologic pathology, 2010, Volume: 38, Issue:4

    Topics: Analysis of Variance; Animals; Arylamine N-Acetyltransferase; Benzoflavones; beta-Naphthoflavone; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochromes; Drug Synergism; Enzyme Inhibitors; Immunohistochemistry; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Organ Specificity; Quinoxalines; Rats; Rats, Inbred F344

2010
Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.
    Archives of toxicology, 2011, Volume: 85, Issue:9

    Topics: Animals; beta-Naphthoflavone; Body Weight; Cytochrome P-450 CYP1A1; Diethylnitrosamine; Enzyme Induction; Flutamide; Gene Expression; Glutathione S-Transferase pi; Hepatectomy; Immunohistochemistry; Indoles; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Oxidative Stress; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; RNA, Messenger

2011
Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats.
    Toxicology, 2011, Apr-28, Volume: 283, Issue:1

    Topics: Animals; Apoptosis; beta-Naphthoflavone; Carcinogens; Glutathione Transferase; Heme Oxygenase (Decyclizing); Immunohistochemistry; Liver Neoplasms, Experimental; Male; Oxidative Stress; Quercetin; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2011
Threshold dose of liver tumor promoting effect of β-naphthoflavone in rats.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Chemokine CCL2; Cyclooxygenase 2; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochromes; Diethylnitrosamine; Dose-Response Relationship, Drug; Glucuronosyltransferase; Glutathione Peroxidase; Glutathione Transferase; Hepatectomy; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred F344; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Thiobarbituric Acid Reactive Substances; Up-Regulation

2012
Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:5

    Topics: Animals; beta-Naphthoflavone; Carbon Tetrachloride; Carcinogens; Cyclooxygenase 2; Cytochrome P-450 CYP1A1; Diethylnitrosamine; Drug Synergism; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Oligonucleotide Array Sequence Analysis; Omeprazole; Proton Pump Inhibitors; Quinoxalines; Rats; Rats, Inbred F344

2012
Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:1

    Topics: Animals; beta-Naphthoflavone; Carcinogens; Dose-Response Relationship, Drug; Estradiol; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Indoles; Liver; Liver Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; RNA, Messenger; Toxicogenetics

2006
beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats.
    Toxicology, 2008, Feb-28, Volume: 244, Issue:2-3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; beta-Naphthoflavone; Blotting, Western; Cell Proliferation; Deoxyguanosine; Diethylnitrosamine; Enzyme Inhibitors; Glutathione Transferase; Hepatectomy; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Precancerous Conditions; Rats; Rats, Inbred F344; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; Thiobarbituric Acid Reactive Substances

2008
The rat quinone reductase antioxidant response element. Identification of the nucleotide sequence required for basal and inducible activity and detection of antioxidant response element-binding proteins in hepatoma and non-hepatoma cell lines.
    The Journal of biological chemistry, 1995, Oct-13, Volume: 270, Issue:41

    Topics: Animals; Antioxidants; Base Sequence; Benzoflavones; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Consensus Sequence; DNA Mutational Analysis; DNA-Binding Proteins; Enhancer Elements, Genetic; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Molecular Sequence Data; Mutagenesis; NAD(P)H Dehydrogenase (Quinone); Point Mutation; Rats; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1995
Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes.
    In vitro cellular & developmental biology. Animal, 1994, Volume: 30A, Issue:9

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Liver; Liver Neoplasms, Experimental; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Testosterone; Tumor Cells, Cultured; Xenobiotics

1994
Half-life of aryl hydrocarbon receptor in Hepa 1 cells: evidence for ligand-dependent alterations in cytosolic receptor levels.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Nucleus; Cytosol; Half-Life; Ligands; Liver Neoplasms, Experimental; Mice; Receptors, Aryl Hydrocarbon; Receptors, Drug; Tumor Cells, Cultured

1993
Hepatocarcinogenic potency of mixed and pure enantiomers of trans-7,8-dihydrobenzo[a]pyrene-7,8-diol in trout.
    Cancer letters, 1993, Volume: 68, Issue:2-3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Tetrachloride; Dihydroxydihydrobenzopyrenes; Disease Models, Animal; Embryo, Nonmammalian; Liver Neoplasms, Experimental; Microinjections; Stereoisomerism; Trout

1993
Different pathways for mitogenic and enzyme induction signal transduction by cytochrome P450 inducers.
    Biochemistry. Biokhimiia, 1999, Volume: 64, Issue:8

    Topics: Animals; Benz(a)Anthracenes; beta-Naphthoflavone; Cell Division; Cytochrome P-450 Enzyme System; Dimethyl Fumarate; Enzyme Induction; Fumarates; Liver Neoplasms, Experimental; Mitosis; p-Chloromercuribenzoic Acid; Radiation-Sensitizing Agents; Rats; Signal Transduction; Tumor Cells, Cultured; Xenobiotics

1999
Influence of beta-naphthoflavone on 7,12-dimethylbenz(a)anthracene metabolism, DNA adduction, and tumorigenicity in rainbow trout.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cells, Cultured; Cytochrome P-450 CYP1A1; Diet; DNA Adducts; DNA Damage; DNA Repair; Drug Interactions; Enzyme Inhibitors; Liver; Liver Neoplasms, Experimental; Mice; Microsomes, Liver; Oncorhynchus mykiss

2000
Changes of CYP1A1, GST, and ALDH3 enzymes in hepatoma cell lines undergoing enhanced lipid peroxidation.
    Free radical biology & medicine, 2000, Volume: 29, Issue:11

    Topics: Aldehyde Dehydrogenase; Animals; Arachidonic Acid; beta-Naphthoflavone; Blotting, Western; Cell Survival; Cytochrome P-450 CYP1A1; Glutathione Transferase; Lipid Peroxidation; Liver Neoplasms, Experimental; Rats; Tumor Cells, Cultured

2000
Rat liver NAD(P)H: Quinone reductase. Regulation of quinone reductase gene expression by planar aromatic compounds and determination of the exon structure of the quinone reductase structural gene.
    The Journal of biological chemistry, 1989, Dec-25, Volume: 264, Issue:36

    Topics: Amino Acid Sequence; Animals; Azo Compounds; Base Sequence; Benzoflavones; beta-Naphthoflavone; Carcinoma, Hepatocellular; Cell Line; Exons; Flavonoids; Gene Expression Regulation, Enzymologic; Genes; Glutathione Transferase; Humans; Introns; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; NAD(P)H Dehydrogenase (Quinone); Oligonucleotide Probes; Quinone Reductases; Rats; RNA, Messenger; Staining and Labeling; Transcription, Genetic; Tumor Cells, Cultured

1989
Metaplastic pancreatic cells in liver tumors induced by diethylnitrosamine.
    Experimental and molecular pathology, 1989, Volume: 50, Issue:1

    Topics: Adenoma, Bile Duct; Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Diethylnitrosamine; Indoles; Liver; Liver Neoplasms, Experimental; Metaplasia; Pancreas; Trout

1989
Modification of transplacental tumorigenesis by 3-methylcholanthrene in mice by genotype at the Ah locus and pretreatment with beta-naphthoflavone.
    Cancer research, 1989, Apr-01, Volume: 49, Issue:7

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Female; Fetal Diseases; Fetus; Flavonoids; Genotype; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Receptors, Aryl Hydrocarbon; Receptors, Drug

1989
The effect of polycyclic aromatic hydrocarbons on choline kinase activity in mouse hepatoma cells.
    Biochimica et biophysica acta, 1989, Aug-08, Volume: 1004, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Choline Kinase; Dimethyl Sulfoxide; Enzyme Induction; Liver Neoplasms, Experimental; Mice; Phosphotransferases; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Receptors, Cell Surface; Tumor Cells, Cultured

1989
Glutathione S-transferase Ya subunit gene: identification of regulatory elements required for basal level and inducible expression.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:4

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Enzyme Induction; Genes; Glutathione Transferase; Humans; Liver Neoplasms, Experimental; Mice; Promoter Regions, Genetic; Rats; Receptors, Aryl Hydrocarbon; Receptors, Drug; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Tumor Cells, Cultured

1988
Biochemical properties of carcinogen-metabolizing enzymes in cultured hepatoma cells.
    Toxicologic pathology, 1987, Volume: 15, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cell Line; Cycloheximide; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Liver Neoplasms, Experimental; Metyrapone; Protein Biosynthesis; Rats

1987
Inhibition of aflatoxin B1-hepatocarcinogenesis in rats by beta-naphthoflavone.
    Carcinogenesis, 1985, Volume: 6, Issue:5

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Diet; Enzyme Induction; Flavonoids; Inactivation, Metabolic; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344; Vegetables

1985