beta-naphthoflavone has been researched along with Disease Models, Animal in 9 studies
beta-Naphthoflavone: A polyaromatic hydrocarbon inducer of P4501A1 and P4501A2 cytochromes. (Proc Soc Exp Biol Med 1994 Dec:207(3):302-308)
beta-naphthoflavone : An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)." | 8.02 | Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021) |
| "In order to discover and develop drug-like anti-inflammatory agents against arthritis, based on "Hit" we found earlier and to overcome drawbacks of toxicity, twelve series of total 89 novel pyrimidine, pyrazolo[4,3-d]pyrimidine and thieno[3,2-d]pyrimidine derivatives were designed, synthesized and screened for their anti-inflammatory activity against NO and toxicity for normal liver cells (LO2)." | 4.02 | Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis. ( Chen, LZ; Huang, X; Liu, MM; Liu, XH; Ma, D; Shi, JB; Shu, HY; Wu, J; Yu, YL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, LZ | 1 |
| Shu, HY | 1 |
| Wu, J | 1 |
| Yu, YL | 1 |
| Ma, D | 1 |
| Huang, X | 1 |
| Liu, MM | 1 |
| Liu, XH | 1 |
| Shi, JB | 1 |
| Büller, NV | 1 |
| Rosekrans, SL | 1 |
| Metcalfe, C | 1 |
| Heijmans, J | 1 |
| van Dop, WA | 1 |
| Fessler, E | 1 |
| Jansen, M | 1 |
| Ahn, C | 1 |
| Vermeulen, JL | 1 |
| Westendorp, BF | 1 |
| Robanus-Maandag, EC | 1 |
| Offerhaus, GJ | 1 |
| Medema, JP | 1 |
| D'Haens, GR | 1 |
| Wildenberg, ME | 1 |
| de Sauvage, FJ | 1 |
| Muncan, V | 1 |
| van den Brink, GR | 1 |
| Dewa, Y | 1 |
| Nishimura, J | 1 |
| Jin, M | 1 |
| Kawai, M | 1 |
| Saegusa, Y | 1 |
| Harada, T | 1 |
| Shibutani, M | 1 |
| Mitsumori, K | 1 |
| Malejka-Giganti, D | 1 |
| Bennett, KK | 1 |
| Culp, SJ | 1 |
| Beland, FA | 1 |
| Shinozuka, H | 1 |
| Bliss, RL | 1 |
| Meyer, RP | 1 |
| Lindberg, RL | 1 |
| Hoffmann, F | 1 |
| Meyer, UA | 1 |
| Battelli, LA | 1 |
| Ghanem, MM | 1 |
| Kashon, ML | 1 |
| Barger, M | 1 |
| Ma, JY | 1 |
| Simoskevitz, RL | 1 |
| Miles, PR | 1 |
| Hubbs, AF | 1 |
| Shachter, NS | 1 |
| Hayek, T | 1 |
| Leff, T | 1 |
| Smith, JD | 1 |
| Rosenberg, DW | 1 |
| Walsh, A | 1 |
| Ramakrishnan, R | 1 |
| Goldberg, IJ | 1 |
| Ginsberg, HN | 1 |
| Breslow, JL | 1 |
| Kelly, JD | 1 |
| Dutchuk, M | 1 |
| Hendricks, JD | 1 |
| Williams, DE | 1 |
| Rice, JM | 1 |
| Kovatch, RM | 1 |
| Anderson, LM | 1 |
9 other studies available for beta-naphthoflavone and Disease Models, Animal
| Article | Year |
|---|---|
Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
Topics: Administration, Oral; Animals; Arthritis; Cells, Cultured; Dimerization; Disease Models, Animal; Dos | 2021 |
Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Autocrine Communication; beta-Naphthoflavone; Biomarke | 2015 |
Molecular expression analysis of beta-naphthoflavone-induced hepatocellular tumors in rats.
Topics: Adenoma, Liver Cell; Animals; beta-Naphthoflavone; Body Weight; Cell Cycle Proteins; Cell Proliferat | 2009 |
Suppression of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis by pre-initiation treatment of rats with beta-naphthoflavone coincides with decreased levels of the carcinogen-derived DNA adducts in the mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; beta-Naphthoflavone; Carcinogens; Cytochr | 2005 |
Cytosolic persistence of mouse brain CYP1A1 in chronic heme deficiency.
Topics: Animals; beta-Naphthoflavone; Brain; Chronic Disease; Cytochrome P-450 CYP1A1; Cytosol; Disease Mode | 2005 |
Crystalline silica is a negative modifier of pulmonary cytochrome P-4501A1 induction.
Topics: Air Pollutants; Animals; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Dise | 2008 |
Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.
Topics: Animals; Apolipoprotein C-II; Apolipoproteins C; Benzoflavones; beta-Naphthoflavone; Cytochrome P-45 | 1994 |
Hepatocarcinogenic potency of mixed and pure enantiomers of trans-7,8-dihydrobenzo[a]pyrene-7,8-diol in trout.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Tetrachloride; Dihydroxydihydrobenzopyrenes; Dis | 1993 |
Intraperitoneal mesotheliomas induced in mice by a polycyclic aromatic hydrocarbon.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Disease Models, Animal; Drug Interactions; Female; Meso | 1989 |