Compounds > beta-n-methylamino-l-alanine
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beta-n-methylamino-l-alanine and Parkinsonian Disorders

beta-n-methylamino-l-alanine has been researched along with Parkinsonian Disorders in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (55.56)29.6817
2010's7 (38.89)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Brooks, J; Burton, B; Collins, K; Marx, K; Moore, E; Osowski, K; Pawlus, M; Renner, A; Riley, J; Rowe, J; Wilcox, K1
Banack, SA; Cox, PA1
Cox, PA; Guillemin, GJ; Kostrzewa, RM1
Chernoff, N; Diggs, DL; Faison, BD; Francis, BM; Hill, DJ; Lang, JR; Larue, MM; Le, TT; Loftin, KA; Lugo, JN; Schmid, JE; Winnik, WM1
Banack, SA; Cox, PA; Kokubo, Y; Kuzuhara, S; Metcalf, JS; Morimoto, S; Murayama, S; Togashi, T1
Nunn, PB1
Cai, HY; Han, S; Jiang, H; Tian, KW; Zhang, YY1
Cui, AM; Davenport, B; Garruto, RM; Go, RC; Heizer, JW; Hermosura, MC; Mocz, G; Perraud, AL; Schmitz, C; Shetler, CM1
Banack, SA; Bradley, WG; Cox, PA1
Cruz-Aguado, R; Shaw, CA1
Kisby, G; Palmer, V; Spencer, PS1
Banack, SA; Bradley, WG; Cheng, R; Nunn, PB1
Banack, SA; Cox, PA; Murch, SJ; Sacks, OW; Steele, JC1
Galasko, D; Li, K; Montine, TJ; Perl, DP1
Miller, G1
Banack, S; Cox, PA; Murch, S; Sacks, O1
Papapetropoulos, S1
Kuzuhara, S1

Reviews

4 review(s) available for beta-n-methylamino-l-alanine and Parkinsonian Disorders

ArticleYear
BMAA and Neurodegenerative Illness.
    Neurotoxicity research, 2018, Volume: 33, Issue:1

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria Toxins; Excitatory Amino Acid Agonists; Humans; Parkinsonian Disorders

2018
A critical review of the postulated role of the non-essential amino acid, β-N-methylamino-L-alanine, in neurodegenerative disease in humans.
    Journal of toxicology and environmental health. Part B, Critical reviews, 2017, Volume: 20, Issue:4

    Topics: Alzheimer Disease; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria; Cyanobacteria Toxins; Cycas; Flour; Humans; Neurodegenerative Diseases; Neurotoxins; Parkinsonian Disorders

2017
Is there a role for naturally occurring cyanobacterial toxins in neurodegeneration? The beta-N-methylamino-L-alanine (BMAA) paradigm.
    Neurochemistry international, 2007, Volume: 50, Issue:7-8

    Topics: Amino Acids, Diamino; Cyanobacteria Toxins; Diet; Guam; Humans; Motor Neuron Disease; Nerve Degeneration; Neurodegenerative Diseases; Neurotoxins; Parkinsonian Disorders

2007
[Revisit to Kii ALS--the innovated concept of ALS-Parkinsonism-dementia complex, clinicopathological features, epidemiology and etiology].
    Brain and nerve = Shinkei kenkyu no shinpo, 2007, Volume: 59, Issue:10

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Brain; Cyanobacteria Toxins; Dementia; DNA-Binding Proteins; Humans; Japan; Minerals; Morbidity; Mutation; Parkinsonian Disorders; Superoxide Dismutase; Superoxide Dismutase-1; tau Proteins

2007

Other Studies

14 other study(ies) available for beta-n-methylamino-l-alanine and Parkinsonian Disorders

ArticleYear
The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria Toxins; Glioblastoma; Humans; Neuroblastoma; Neurotoxins; Parkinsonian Disorders

2023
Creating a Simian Model of Guam ALS/PDC Which Reflects Chamorro Lifetime BMAA Exposures.
    Neurotoxicity research, 2018, Volume: 33, Issue:1

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Brain; Chlorocebus aethiops; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Guam; Humans; Male; Neurofibrillary Tangles; Parkinsonian Disorders; Plaque, Amyloid

2018
β-N-methylamino-l-alanine analysis in the brains of patients with Kii ALS/PDC.
    Neurology, 2017, 09-05, Volume: 89, Issue:10

    Topics: Aged; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Brain; Chromatography, High Pressure Liquid; Cyanobacteria Toxins; Dementia; Female; Humans; Japan; Male; Mass Spectrometry; Middle Aged; Parkinsonian Disorders

2017
50 years of research on α-amino-β-methylaminopropionic acid (β-methylaminoalanine).
    Phytochemistry, 2017, Volume: 144

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria Toxins; Cycas; Dementia; Guam; Humans; Molecular Structure; Parkinsonian Disorders; Seeds

2017
Angiopoietin-1 and ανβ3 integrin peptide promote the therapeutic effects of L-serine in an amyotrophic lateral sclerosis/Parkinsonism dementia complex model.
    Aging, 2018, 11-25, Volume: 10, Issue:11

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Angiopoietin-1; Animals; Cyanobacteria Toxins; Gene Expression Regulation; Integrin alpha Chains; Male; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley

2018
Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Nov-18, Volume: 105, Issue:46

    Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Calcium; Calcium Signaling; Cell Membrane; Conserved Sequence; Cyanobacteria Toxins; Evolution, Molecular; Guam; Humans; Hydrogen Peroxide; Ion Channel Gating; Leucine; Magnesium; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Mutation; Oxidative Stress; Parkinsonian Disorders; Proline; Temperature; TRPM Cation Channels

2008
The ALS/PDC syndrome of Guam and the cycad hypothesis.
    Neurology, 2009, Feb-03, Volume: 72, Issue:5

    Topics: Amino Acids; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Bacterial Toxins; Brain; Causality; Cyanobacteria Toxins; Cycas; Dementia; Flour; Guam; Hazardous Substances; Humans; Marine Toxins; Microcystins; Parkinsonian Disorders; Plant Extracts; Syndrome

2009
The ALS/PDC syndrome of Guam and the cycad hypothesis.
    Neurology, 2009, Feb-03, Volume: 72, Issue:5

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Bacterial Toxins; Causality; Cyanobacteria Toxins; Cycas; Data Interpretation, Statistical; Dementia; Epidemiologic Research Design; Epidemiologic Studies; Flour; Guam; Hazardous Substances; Humans; Incidence; Marine Toxins; Microcystins; Parkinsonian Disorders; Plant Extracts; Sex Distribution; Syndrome

2009
The ALS/PDC syndrome of Guam and the cycad hypothesis.
    Neurology, 2009, Feb-03, Volume: 72, Issue:5

    Topics: alpha-Synuclein; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Bacterial Toxins; Causality; Cyanobacteria Toxins; Cycas; Dementia; Disease Models, Animal; Epidemiologic Research Design; Epidemiologic Studies; Flour; Guam; Hazardous Substances; Humans; Incidence; Indonesia; Japan; Marine Toxins; Methylazoxymethanol Acetate; Microcystins; Nerve Degeneration; Parkinsonian Disorders; Plant Extracts; Syndrome; Tauopathies

2009
Washed cycad flour contains β-N-methyl amino-L-alanine and may explain parkinsonism symptoms.
    Annals of neurology, 2011, Volume: 69, Issue:2

    Topics: Amino Acids, Diamino; Animals; Cyanobacteria Toxins; Cycas; Flour; Neurotoxins; Parkinsonian Disorders; Plant Extracts; Rats

2011
Occurrence of beta-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam.
    Acta neurologica Scandinavica, 2004, Volume: 110, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Bacterial Toxins; Case-Control Studies; Cyanobacteria Toxins; Dementia; Female; Frontal Lobe; Guam; Humans; Male; Marine Toxins; Microcystins; Middle Aged; Neurotoxins; Parkinsonian Disorders

2004
Lack of beta-methylamino-l-alanine in brain from controls, AD, or Chamorros with PDC.
    Neurology, 2005, Sep-13, Volume: 65, Issue:5

    Topics: Aged; Alzheimer Disease; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Brain; Brain Chemistry; Canada; Cyanobacteria Toxins; Environmental Exposure; Female; Guam; Humans; Male; Middle Aged; Parkinsonian Disorders; Reproducibility of Results

2005
Neurodegenerative disease. Guam's deadly stalker: on the loose worldwide?
    Science (New York, N.Y.), 2006, Jul-28, Volume: 313, Issue:5786

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Brain Chemistry; Chiroptera; Cyanobacteria; Cyanobacteria Toxins; Cycadopsida; Diet; Ethnicity; Food Chain; Guam; Humans; Models, Animal; Neurodegenerative Diseases; Neurotoxins; Parkinsonian Disorders; Seeds; Water Supply

2006
Commentary on: Return of the cycad hypothesis--does the amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS/PDC) of Guam have new implications for global health?
    Neuropathology and applied neurobiology, 2006, Volume: 32, Issue:6

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Bacterial Toxins; Cyanobacteria; Cyanobacteria Toxins; Cycas; Diet; Excitatory Amino Acid Agonists; Guam; Humans; Marine Toxins; Microcystins; Parkinsonian Disorders

2006