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beta-n-methylamino-l-alanine and Disease Models, Animal

beta-n-methylamino-l-alanine has been researched along with Disease Models, Animal in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's0 (0.00)18.2507
2000's5 (23.81)29.6817
2010's13 (61.90)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Angelis, G; Pampalakis, G; Sotiropoulou, G; Vekrellis, K; Zingkou, E1
Banack, SA; Beierschmitt, A; Bradley, WG; Cox, PA; Davis, DA; Garamszegi, SP; Hagan, MJ; Lecusay, PD; Mash, DC; Metcalf, JS; Palmour, RM; Powell, JT1
Downing, S; Downing, TG; Scott, LL1
Banack, SA; Cox, PA1
Downing, TG; Scott, LL2
Arahuetes, RM; de Munck, E; Gil, C; Martínez, A; Miguel, BG; Muñoz-Sáez, E; Ojeda, I; Solas, MT1
Basile, M; Mash, DC; Xie, X1
Kisby, GE; Moore, H; Spencer, PS1
Brittebo, EB; Ewing, AG; Gerber, L; Hanrieder, J; Karlsson, O; Persson Sandelius, Å1
Acab, A; Chiang, BJ; Hsu, CI; Liu, J; Tao, A; Weiss, JH; Wu, R; Yin, HZ; Yu, S1
Arahuetes, RM; de Munck, E; Martínez, A; Miguel, BG; Muñoz-Sáez, E; Solas, MT1
Banack, SA; Cox, PA; Davis, DA; Mash, DC; Metcalf, JS1
Kwok, S; Lavin, T; Lovejoy, E; Powers, S; Sher, RB1
Kisby, G; Palmer, V; Spencer, PS1
Nunn, PB1
Bradley, WG; Escala, W; Papapetropoulos, S; Zhai, RG; Zhou, X1
Codd, GA; Kashmiri, S; Metcalf, JS; Purdie, EL1
Escala, W; Papapetropoulos, S; Zhai, RG; Zhou, X1
Karamyan, VT; Speth, RC1
Gajdusek, DC; Garruto, RM; Yanagihara, R1

Reviews

3 review(s) available for beta-n-methylamino-l-alanine and Disease Models, Animal

ArticleYear
A chemogenomic approach is required for effective treatment of amyotrophic lateral sclerosis.
    Clinical and translational medicine, 2022, Volume: 12, Issue:1

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria Toxins; Cycas; Disease Models, Animal; Mice

2022
Animal models of brain maldevelopment induced by cycad plant genotoxins.
    Birth defects research. Part C, Embryo today : reviews, 2013, Volume: 99, Issue:4

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyanobacteria Toxins; Cycas; Disease Models, Animal; DNA Damage; Humans; Mutagens; Neurotoxins

2013
Animal models of BMAA neurotoxicity: a critical review.
    Life sciences, 2008, Jan-30, Volume: 82, Issue:5-6

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyanobacteria Toxins; Disease Models, Animal; Environmental Exposure; Excitatory Amino Acid Antagonists; Food Chain; Food Contamination; Guam; Meat; Neurotoxins; Parkinson Disease, Secondary; Plants, Edible

2008

Other Studies

18 other study(ies) available for beta-n-methylamino-l-alanine and Disease Models, Animal

ArticleYear
l-Serine Reduces Spinal Cord Pathology in a Vervet Model of Preclinical ALS/MND.
    Journal of neuropathology and experimental neurology, 2020, 04-01, Volume: 79, Issue:4

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Chlorocebus aethiops; Cyanobacteria Toxins; Disease Models, Animal; Male; Microglia; Motor Neuron Disease; Motor Neurons; Pyramidal Tracts; Serine; Spinal Cord

2020
The Evaluation of BMAA Inhalation as a Potential Exposure Route Using a rat Model.
    Neurotoxicity research, 2018, Volume: 33, Issue:1

    Topics: Amino Acids, Diamino; Animals; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Inhalation Exposure; Male; Necrosis; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Tritium

2018
Creating a Simian Model of Guam ALS/PDC Which Reflects Chamorro Lifetime BMAA Exposures.
    Neurotoxicity research, 2018, Volume: 33, Issue:1

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Brain; Chlorocebus aethiops; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Guam; Humans; Male; Neurofibrillary Tangles; Parkinsonian Disorders; Plaque, Amyloid

2018
Β-N-Methylamino-L-Alanine (BMAA) Toxicity Is Gender and Exposure-Age Dependent in Rats.
    Toxins, 2017, 12-27, Volume: 10, Issue:1

    Topics: Aging; Amino Acids, Diamino; Animals; Animals, Newborn; Behavior, Animal; Cyanobacteria Toxins; Disease Models, Animal; Female; Learning; Locomotion; Male; Neurotoxins; Olfactory Perception; Rats, Sprague-Dawley; Sex Characteristics

2017
A Single Neonatal Exposure to BMAA in a Rat Model Produces Neuropathology Consistent with Neurodegenerative Diseases.
    Toxins, 2017, 12-29, Volume: 10, Issue:1

    Topics: Amino Acids, Diamino; Animals; Animals, Newborn; Brain; Cyanobacteria Toxins; Disease Models, Animal; Female; Male; Neurodegenerative Diseases; Neurons; Neurotoxins; Rats, Sprague-Dawley; Spinal Cord

2017
β-N-methylamino-l-alanine causes neurological and pathological phenotypes mimicking Amyotrophic Lateral Sclerosis (ALS): the first step towards an experimental model for sporadic ALS.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Caspase 3; Choline; Creatinine; Cyanobacteria Toxins; Disease Models, Animal; DNA-Binding Proteins; Endoplasmic Reticulum; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Magnetic Resonance Spectroscopy; Male; Mitochondria; Motor Activity; Motor Cortex; Nerve Degeneration; Neurologic Examination; Phenotype; Rats; Rats, Wistar; Spinal Cord; Time Factors

2013
Cerebral uptake and protein incorporation of cyanobacterial toxin β-N-methylamino-L-alanine.
    Neuroreport, 2013, Oct-02, Volume: 24, Issue:14

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Bacterial Toxins; Brain; Cyanobacteria Toxins; Dementia; Disease Models, Animal; Half-Life; Marine Toxins; Mice; Microcystins; Neurotoxins

2013
High resolution metabolite imaging in the hippocampus following neonatal exposure to the environmental toxin BMAA using ToF-SIMS.
    ACS chemical neuroscience, 2014, Jul-16, Volume: 5, Issue:7

    Topics: Amino Acids, Diamino; Animals; Animals, Newborn; Brain Diseases; Cyanobacteria Toxins; Disease Models, Animal; Gliosis; Hazardous Substances; Hippocampus; Immunohistochemistry; Male; Mass Spectrometry; Multivariate Analysis; Rats, Wistar; Signal Processing, Computer-Assisted

2014
Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord.
    Experimental neurology, 2014, Volume: 261

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Cell Survival; Cyanobacteria Toxins; Disease Models, Animal; DNA-Binding Proteins; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Gliosis; Glutamate Plasma Membrane Transport Proteins; Humans; Male; Rats; Rats, Transgenic; Spinal Cord; Superoxide Dismutase; Tyrosine

2014
Morphometric and neurochemical alterations found in l-BMAA treated rats.
    Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:3

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria; Cyanobacteria Toxins; Diatoms; Disease Models, Animal; Humans; Male; Motor Cortex; Muscle, Skeletal; Neurotoxins; Rats

2015
Do vervets and macaques respond differently to BMAA?
    Neurotoxicology, 2016, Volume: 57

    Topics: Alzheimer Disease; Amino Acids, Diamino; Animals; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Macaca fascicularis; Neurofibrillary Tangles

2016
Editor's Highlight: Embryonic Exposure to the Environmental Neurotoxin BMAA Negatively Impacts Early Neuronal Development and Progression of Neurodegeneration in the Sod1-G93R Zebrafish Model of Amyotrophic Lateral Sclerosis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, 05-01, Volume: 157, Issue:1

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Cyanobacteria Toxins; Disease Models, Animal; Disease Progression; Environmental Exposure; Genotype; Neurotoxins; Superoxide Dismutase-1; Zebrafish

2017
The ALS/PDC syndrome of Guam and the cycad hypothesis.
    Neurology, 2009, Feb-03, Volume: 72, Issue:5

    Topics: alpha-Synuclein; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Bacterial Toxins; Causality; Cyanobacteria Toxins; Cycas; Dementia; Disease Models, Animal; Epidemiologic Research Design; Epidemiologic Studies; Flour; Guam; Hazardous Substances; Humans; Incidence; Indonesia; Japan; Marine Toxins; Methylazoxymethanol Acetate; Microcystins; Nerve Degeneration; Parkinsonian Disorders; Plant Extracts; Syndrome; Tauopathies

2009
Three phases of research on beta-N-methylamino-L-alanine (BMAA)--a neurotoxic amino acid.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2009, Volume: 10 Suppl 2

    Topics: Amino Acids; Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Biomedical Research; Blood-Brain Barrier; Cyanobacteria Toxins; Disease Models, Animal; Humans; Neurotoxicity Syndromes; Neurotoxins; Primates; Rats

2009
BMAA neurotoxicity in Drosophila.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2009, Volume: 10 Suppl 2

    Topics: Alanine; Amino Acids, Diamino; Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Glutamic Acid; Leucine; Longevity; Lysine; Male; Neurotoxicity Syndromes; Neurotoxins

2009
Toxicity of the cyanobacterial neurotoxin beta-N-methylamino-L-alanine to three aquatic animal species.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2009, Volume: 10 Suppl 2

    Topics: Amino Acids, Diamino; Animals; Artemia; Behavior, Animal; Cyanobacteria; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Neurotoxicity Syndromes; Neurotoxins; Photosensitivity Disorders; Procyonidae; Spinal Cord Diseases; Time Factors; Zebrafish

2009
β-N-methylamino-L-alanine induces neurological deficits and shortened life span in Drosophila.
    Toxins, 2010, Volume: 2, Issue:11

    Topics: Amino Acids, Diamino; Animals; Behavior, Animal; Body Burden; Chromatography, High Pressure Liquid; Chronic Disease; Cyanobacteria Toxins; Disease Models, Animal; Drosophila; Excitatory Amino Acid Agonists; Female; Learning; Locomotion; Longevity; Male; Memory; Nervous System; Neurodegenerative Diseases

2010
Cycads and amyotrophic lateral sclerosis/parkinsonism dementia.
    Lancet (London, England), 1988, Nov-05, Volume: 2, Issue:8619

    Topics: Amino Acids, Diamino; Amyotrophic Lateral Sclerosis; Animals; Cyanobacteria Toxins; Dementia; Disease Models, Animal; Female; Humans; Macaca fascicularis; Parkinson Disease, Secondary; Seeds

1988