beta-lapachone has been researched along with Neglected Diseases in 1 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
Neglected Diseases: Diseases that are underfunded and have low name recognition but are major burdens in less developed countries. The World Health Organization has designated six tropical infectious diseases as being neglected in industrialized countries that are endemic in many developing countries (HELMINTHIASIS; LEPROSY; LYMPHATIC FILARIASIS; ONCHOCERCIASIS; SCHISTOSOMIASIS; and TRACHOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leishmania and cancer, reactions including copper-catalyzed azide-alkyne cycloaddition (click chemistry), palladium-catalysed cross couplings, C-H activation reactions, Ullmann couplings and heterocyclisations reported up to July 2019 will be discussed." | 2.61 | Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones. ( Ackermann, L; da Silva Júnior, EN; de Castro, SL; Dhawa, U; Jacob, C; Jardim, GAM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Silva Júnior, EN | 1 |
| Jardim, GAM | 1 |
| Jacob, C | 1 |
| Dhawa, U | 1 |
| Ackermann, L | 1 |
| de Castro, SL | 1 |
1 review available for beta-lapachone and Neglected Diseases
| Article | Year |
|---|---|
Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones.
Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Cell Line, Tumor; Cell Proliferation; Chagas D | 2019 |