Page last updated: 2024-10-30

beta-lapachone and Malaria, Falciparum

beta-lapachone has been researched along with Malaria, Falciparum in 2 studies

beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Miller, ME1
Parrott, EE1
Singh, R1
Nelson, SW1
Patel, OPS1
Beteck, RM1
Legoabe, LJ1

Reviews

1 review available for beta-lapachone and Malaria, Falciparum

ArticleYear
Antimalarial application of quinones: A recent update.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic

2021

Other Studies

1 other study available for beta-lapachone and Malaria, Falciparum

ArticleYear
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:6

    Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle

2014