beta-lapachone has been researched along with Carcinoma, Anaplastic in 2 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of the present study was to investigate the effect of beta-lapachone, a quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae), on the cell growth and apoptosis in human lung carcinoma cell line A549." | 7.73 | Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity. ( Choi, YH; Woo, HJ, 2005) |
| "beta-lapachone induced cell death in a spectrum of human carcinoma cells, including nonproliferating cells." | 7.70 | Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by beta-lapachone in human carcinoma cells. ( Li, CJ; Li, YZ; Pardee, AB; Pinto, AV, 1999) |
| "The objective of the present study was to investigate the effect of beta-lapachone, a quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae), on the cell growth and apoptosis in human lung carcinoma cell line A549." | 3.73 | Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity. ( Choi, YH; Woo, HJ, 2005) |
| "beta-lapachone induced cell death in a spectrum of human carcinoma cells, including nonproliferating cells." | 3.70 | Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by beta-lapachone in human carcinoma cells. ( Li, CJ; Li, YZ; Pardee, AB; Pinto, AV, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woo, HJ | 1 |
| Choi, YH | 1 |
| Li, YZ | 1 |
| Li, CJ | 1 |
| Pinto, AV | 1 |
| Pardee, AB | 1 |
2 other studies available for beta-lapachone and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity.
Topics: Apoptosis; Carcinoma; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Humans; | 2005 |
Release of mitochondrial cytochrome C in both apoptosis and necrosis induced by beta-lapachone in human carcinoma cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Carcinoma; Caspase 3; Caspases; Cell Death; Cytochrome c Gro | 1999 |