beta-lapachone has been researched along with Adult Spinal Muscular Atrophy in 1 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Camptothecin treatment reduced the DNA relaxation activity of DNA topoisomerase I in human fibroblasts." | 1.35 | Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent. ( Funanage, VL; Gómez-Curet, I; Scavina, M; Wang, W; Wu, CY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, CY | 1 |
| Gómez-Curet, I | 1 |
| Funanage, VL | 1 |
| Scavina, M | 1 |
| Wang, W | 1 |
1 other study available for beta-lapachone and Adult Spinal Muscular Atrophy
| Article | Year |
|---|---|
Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent.
Topics: Apoptosis; Camptothecin; Cells, Cultured; DNA Topoisomerases, Type I; Fibroblasts; Humans; Muscular | 2009 |