beta-lapachone has been researched along with Acute Promyelocytic Leukemia in 4 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Planchon, SM | 1 |
| Wuerzberger, S | 1 |
| Frydman, B | 1 |
| Witiak, DT | 1 |
| Hutson, P | 1 |
| Church, DR | 1 |
| Wilding, G | 1 |
| Boothman, DA | 1 |
| Li, CJ | 2 |
| Wang, C | 1 |
| Pardee, AB | 2 |
| Averboukh, L | 1 |
| Chau, YP | 1 |
| Shiah, SG | 1 |
| Don, MJ | 1 |
| Kuo, ML | 1 |
4 other studies available for beta-lapachone and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.
Topics: Apoptosis; Breast Neoplasms; Camptothecin; Cell Division; Dimethyl Sulfoxide; Drug Screening Assays, | 1995 |
Induction of apoptosis by beta-lapachone in human prostate cancer cells.
Topics: Apoptosis; Cell Survival; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Leukemia, Promye | 1995 |
beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.
Topics: Animals; Camptothecin; Cattle; Cell Line; DNA, Kinetoplast; Humans; Kinetics; Leukemia, Promyelocyti | 1993 |
Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cell Differentiation; DNA Fragmentation; Dru | 1998 |