beta-lapachone has been researched along with Abnormalities, Autosome in 1 studies
beta-lapachone: antineoplastic inhibitor of reverse transcriptase, DNA topoisomerase, and DNA polymerase
beta-lapachone : A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The frequencies of chromosomal aberrations and sister-chromatid exchanges (SCE) after exposure to beta-lapachone, an activator of mammalian topoisomerase I, were studied in Chinese hamster cells." | 1.29 | The production of chromosomal alterations by beta-lapachone, an activator of topoisomerase I. ( Berghella, L; De Salvia, R; Degrassi, F, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Degrassi, F | 1 |
| De Salvia, R | 1 |
| Berghella, L | 1 |
1 other study available for beta-lapachone and Abnormalities, Autosome
| Article | Year |
|---|---|
The production of chromosomal alterations by beta-lapachone, an activator of topoisomerase I.
Topics: Animals; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Damage; DNA Topoisomerases, Type I; Enzy | 1993 |