beta-lactams has been researched along with Neutropenia in 46 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (19.57) | 18.7374 |
1990's | 3 (6.52) | 18.2507 |
2000's | 14 (30.43) | 29.6817 |
2010's | 17 (36.96) | 24.3611 |
2020's | 3 (6.52) | 2.80 |
Authors | Studies |
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Daneman, N; Lam, PW; Leis, JA | 1 |
Allos, BM; Cimino, C; Phillips, EJ | 1 |
Fink, G; Horn, S; Kern, WV | 1 |
Abdala, E; Akova, M; Álvarez, R; Cano, A; Carratalà, J; Cervera, C; Clemente, WT; Freifeld, A; Gómez, L; Gottlieb, T; Gudiol, C; Gurguí, M; Herrera, F; Maestro-de la Calle, G; Manzur, A; Martín-Dávila, P; Maschmeyer, G; Meije, Y; Montejo, M; Peghin, M; Rodríguez-Baño, J; Royo-Cebrecos, C; Ruiz-Camps, I; Sukiennik, TC; Tebe, C | 2 |
Tamma, PD; Villegas, MV | 1 |
Auerbach, AD; Dvorak, CC; Levy, ER; Sabnis, AJ; Wattier, RL | 1 |
Bailly, H; Boulay, C; Chouchana, L; Default, A; Kassai, B; Perault-Pochat, MC; Vial, T | 1 |
Aster, RH | 1 |
Crandon, JL; Nicolau, DP; Nordmann, P; Wiskirchen, DE | 1 |
Dickstein, Y; Grozinsky-Glasberg, S; Leibovici, L; Paul, M; Schlesinger, A; Soares-Weiser, K | 1 |
Sick, AC; Tamma, PD; Tschudin-Sutter, S; Turnbull, AE; Weissman, SJ | 1 |
Chemaly, RF; Mahajan, SN; Nesher, L; Rolston, KV; Tverdek, FP | 1 |
Frenck, RW; Fukuda, T; Hahn, A; Hahn, D; Mizuno, T; Vinks, AA | 1 |
Abe, T; Furuuchi, T; Ida, T; Inamura, S; Morinaka, A; Sakakibara, S; Sakamaki, Y; Takata, T; Takayama, Y; Tsujii, N; Tsutsumi, Y; Yamada, K | 1 |
Iguchi, A; Kaneda, M; Kobayashi, R; Nakajima, M; Sato, T | 1 |
Bivas, A; Fraser, A; Leibovici, L; Paul, M; Yahav, D | 1 |
Ernst, EJ; Johnson, SJ; Moores, KG | 1 |
Andresen, D; Burbury, K; Dawson, L; Kelly, A; Lingaratnam, S; O'Reilly, M; Slavin, MA; Tam, CS; Thursky, KA; Turnidge, J; Worth, LJ | 1 |
Cosgrove, SE; Maragakis, LL; Tamma, PD | 1 |
Abbott, IJ; Roberts, JA | 1 |
Banevicius, M; Capitano, B; Kim, MK; Nicolau, D; Nightingale, C; Xuan, D | 1 |
Leibovici, L; Paul, M; Soares-Weiser, K | 1 |
Grozinsky, S; Leibovici, L; Paul, M; Soares-Weiser, K | 2 |
Babalola, C; Banevicius, MA; Maglio, D; Nicolau, DP; Nightingale, CH; Sutherland, C | 1 |
Cirioni, O; D'Amato, G; Giacometti, A; Kamysz, W; Licci, A; Lukasiak, J; Nadolski, P; Riva, A; Scalise, G; Silvestri, C | 1 |
Leibovici, L; Paul, M | 1 |
Bliziotis, IA; Christodoulou, C; Chrysanthopoulou, S; Falagas, ME; Kasiakou, SK; Michalopoulos, A; Samonis, G | 1 |
Peralta, G; Sánchez-Santiago, MB | 1 |
Ahmed, A; Chua, M; Chun, W; Hsueh, PR; Hussain, Y; Jootar, S; Jun, HX; Lee, DG; Lim, V; Lin, SF; Liu, CY; Liu, YC; Matsumoto, T; Ong, A; Picazo, JJ; Purushotaman, SV; Ranuhardy, D; Reksodiputro, AH; Suwangool, P; Tamura, K; Zhixiang, S | 1 |
Batard, E; Caillon, J; Kergueris, MF; Le Conte, P; Moreau, P; Navas, D; Potel, G | 1 |
Durnaá, B; Dzierzanowska, D | 1 |
Clarke, MJ; Edwards, SJ; Emmas, CE; Wordsworth, S | 1 |
Blacklock, H; Boesen, E; Corringham, R; Gray, R; Hann, I; Mohiuddin, J; Noone, P; Prentice, HG; Sage, R; Stirling, L | 1 |
Greene, WH | 1 |
Grint, P; Metcalfe, P; Minchinton, RM; Murphy, MF; Waters, AH | 1 |
Gaus, W; Kern, WV; Kurrle, E; Moritz, T; Reichle, A; Rozdzinski, E; Schmeiser, T | 1 |
Alestig, K; Belin, L; Hogevik, H; Olaison, L | 1 |
Eich, G; Neftel, KA | 1 |
Brenner, MK; Hoffbrand, AV; Kibbler, CC; Noone, P; Prentice, HG; Sage, RJ | 1 |
DeJace, P; Klastersky, J | 1 |
Brückner, O; Hahn, H; Marre, R; Trautmann, M | 1 |
Dewdney, JM; Edwards, RG; Lee, D; Neftel, KA; Wälti, M | 1 |
Young, LS | 1 |
Nelson, JD | 1 |
15 review(s) available for beta-lactams and Neutropenia
Article | Year |
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A Review of β-Lactam-Associated Neutropenia and Implications for Cross-reactivity.
Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Child; Humans; Neutropenia | 2021 |
Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cause of Death; Child; Combined Modality Therapy; Humans; Neoplasms; Neutropenia; Randomized Controlled Trials as Topic | 2013 |
Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Fever; Humans; Imipenem; Meropenem; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Thienamycins | 2010 |
Combination therapy for treatment of infections with gram-negative bacteria.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Clinical Trials as Topic; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Neutropenia; Treatment Outcome | 2012 |
Infusional β-lactam antibiotics in febrile neutropenia: has the time come?
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Fever of Unknown Origin; Humans; Infusions, Intravenous; Neutropenia; Treatment Outcome | 2012 |
Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for fever with neutropenia: systematic review and meta-analysis.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cause of Death; Drug Therapy, Combination; Fever; Humans; Neutropenia; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Superinfection; Treatment Failure | 2003 |
Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropaenia.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cause of Death; Drug Therapy, Combination; Humans; Neoplasms; Neutropenia; Randomized Controlled Trials as Topic | 2003 |
Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Therapy, Combination; Fever; Humans; Neoplasms; Neutropenia; Randomized Controlled Trials as Topic; Treatment Outcome | 2005 |
[Beta-lactam-induced neutropenia. An old forgotten companion].
Topics: Anti-Bacterial Agents; beta-Lactams; Humans; Neutropenia | 2005 |
[Infection in neutropenic cancer patients--etiology, microbiological diagnostics, treatment].
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactams; Drug Combinations; Female; Fever; Humans; Male; Microbial Sensitivity Tests; Neoplasms; Neutropenia | 2006 |
Carbapenems versus other beta-lactams in treating severe infections in intensive care: a systematic review of randomised controlled trials.
Topics: Bacterial Infections; beta-Lactams; Critical Care; Humans; Neutropenia; Randomized Controlled Trials as Topic; Treatment Outcome | 2008 |
The role of the newer beta-lactam antibiotics in the treatment of infection in compromised hosts.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Humans; Immunosuppression Therapy; Neoplasms; Neutropenia; Sepsis | 1984 |
Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropaenia.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Drug Therapy, Combination; Humans; Neoplasms; Neutropenia; Randomized Controlled Trials as Topic | 2002 |
[Evaluation of hematologic side effects of anti-infective therapy: agranulocytosis caused by beta-lactam antibiotics, vancomycin and amodiaquine].
Topics: Agranulocytosis; Amodiaquine; Animals; Anti-Bacterial Agents; beta-Lactams; Humans; Neutropenia; Vancomycin | 1991 |
Comparative review of combination therapy: two beta-lactams versus beta-lactam plus aminoglycoside.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cellulitis; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Neoplasms; Neutropenia; Pneumonia; Pseudomonas Infections; Sepsis; Urinary Tract Infections | 1986 |
5 trial(s) available for beta-lactams and Neutropenia
Article | Year |
---|---|
Piperacillin/tazobactam plus ceftazidime versus sulbactam/ampicillin plus aztreonam as empirical therapy for fever in severely neutropenic pediatric patients.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Ceftazidime; Child; Child, Preschool; Drug Therapy, Combination; Female; Fever; Humans; Infant; Infant, Newborn; Male; Neoplasms; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Severity of Illness Index; Sulbactam | 2009 |
The results of a randomized trial of empirical antibiotic treatment in febrile neutropenic patients with four beta-lactam/aminoglycoside combinations.
Topics: Agranulocytosis; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Neutropenia; Random Allocation | 1983 |
Once-daily versus thrice-daily dosing of netilmicin in combination with beta-lactam antibiotics as empirical therapy for febrile neutropenic patients.
Topics: Anemia, Aplastic; Anti-Bacterial Agents; beta-Lactams; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Neoplasms; Netilmicin; Neutropenia; Prospective Studies | 1993 |
Do double-beta-lactam combinations prolong neutropenia in patients undergoing chemotherapy or bone marrow transplantation for hematological disease?
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; beta-Lactams; Bone Marrow Transplantation; Clinical Trials as Topic; Double-Blind Method; Female; Hematologic Diseases; Humans; Male; Neutropenia; Random Allocation; Time Factors; Transplantation, Homologous | 1989 |
Comparative review of combination therapy: two beta-lactams versus beta-lactam plus aminoglycoside.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cellulitis; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Neoplasms; Neutropenia; Pneumonia; Pseudomonas Infections; Sepsis; Urinary Tract Infections | 1986 |
27 other study(ies) available for beta-lactams and Neutropenia
Article | Year |
---|---|
Antibiotic-Induced Neutropenia in Patients Receiving Outpatient Parenteral Antibiotic Therapy: a Retrospective Cohort Study.
Topics: Ambulatory Care; Anti-Bacterial Agents; beta-Lactams; Ceftriaxone; Cloxacillin; Humans; Neutropenia; Outpatients; Retrospective Studies; Vancomycin | 2023 |
[Antibiotic stewardship - recent developments].
Topics: Aminoglycosides; Anti-Bacterial Agents; Antimicrobial Stewardship; beta-Lactams; Cephalosporins; Fluoroquinolones; Germany; Humans; Neutropenia; Piperacillin, Tazobactam Drug Combination; Urinary Tract Infections | 2020 |
Efficacy of β-Lactam/β-Lactamase Inhibitor Combinations for the Treatment of Bloodstream Infection Due to Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in Hematological Patients with Neutropenia.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Cohort Studies; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Neutropenia | 2017 |
Use of β-Lactam/β-Lactamase Inhibitors for Extended-Spectrum-β-Lactamase Infections: Defining the Right Patient Population.
Topics: Bacteremia; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Catheter-Related Infections; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Neutropenia; Propensity Score; Urinary Tract Infections | 2017 |
Reducing Second Gram-Negative Antibiotic Therapy on Pediatric Oncology and Hematopoietic Stem Cell Transplantation Services.
Topics: Adolescent; Anti-Bacterial Agents; Antimicrobial Stewardship; beta-Lactams; Child; Child, Preschool; Ciprofloxacin; Drug Combinations; Drug Utilization; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Guidelines as Topic; Hematopoietic Stem Cell Transplantation; Hospitals, Pediatric; Humans; Length of Stay; Medical Oncology; Neutropenia; Pediatrics; Poisson Distribution; San Francisco; Tobramycin; Treatment Outcome | 2017 |
Beta-lactam-induced severe neutropaenia: a descriptive study.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Databases, Factual; Drug Substitution; Female; France; Humans; Male; Middle Aged; Neutropenia; Pharmacovigilance; Prognosis; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Young Adult | 2019 |
Beta-lactam-induced severe neutropenia: a descriptive study.
Topics: Anti-Bacterial Agents; beta-Lactams; Humans; Neutropenia | 2019 |
Efficacy of humanized carbapenem exposures against New Delhi metallo-β-lactamase (NDM-1)-producing enterobacteriaceae in a murine infection model.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactamases; beta-Lactams; Carbapenems; Disease Models, Animal; Doripenem; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ertapenem; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Time Factors | 2013 |
Empiric combination therapy for gram-negative bacteremia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Baltimore; beta-Lactams; Child; Child, Preschool; Cohort Studies; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Empiricism; Female; Gram-Negative Bacterial Infections; Humans; Infant; Kaplan-Meier Estimate; Male; Neutropenia; Odds Ratio; Opportunistic Infections; Propensity Score; Retrospective Studies; Survival Analysis | 2014 |
Ertapenem usage in cancer patients with and without neutropenia: a report on 97 cases from a comprehensive cancer center.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Child; Drug Utilization; Ertapenem; Female; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Retrospective Studies; Treatment Outcome; Young Adult | 2015 |
Pharmacokinetics and pharmacogenomics of β-lactam-induced neutropenia.
Topics: Adolescent; beta-Lactams; Child; Child, Preschool; Female; Humans; Infant; Male; Multidrug Resistance-Associated Proteins; Neutropenia; Organic Anion Transporters, Sodium-Independent; Pharmacogenetics | 2016 |
In vitro and in vivo activities of the diazabicyclooctane OP0595 against AmpC-derepressed Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Humans; Lactams; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Pseudomonas aeruginosa; Pseudomonas Infections | 2017 |
Clinical efficacy of β-lactam/β-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum β-lactamase-producing Enterobacteriaceae in haematological patients with neutropaenia: a study protocol for a retrospectiv
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; beta-Lactams; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Neutropenia; Retrospective Studies; Superinfection | 2017 |
Is double coverage of gram-negative organisms necessary?
Topics: Aminoglycosides; Anti-Infective Agents; beta-Lactams; Drug Resistance, Microbial; Drug Therapy, Combination; Fluoroquinolones; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Neutropenia | 2011 |
Use of empiric antimicrobial therapy in neutropenic fever. Australian Consensus Guidelines 2011 Steering Committee.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Australia; Bacteremia; Bacterial Infections; Bacteriological Techniques; beta-Lactams; Cancer Care Facilities; Disease Management; Drug Resistance, Multiple, Bacterial; Fever; Humans; Immunocompromised Host; Neoplasms; Neutropenia; Risk Assessment; Severity of Illness Index | 2011 |
Pharmacodynamic assessment of ertapenem (MK-0826) against Streptococcus pneumoniae in a murine neutropenic thigh infection model.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Ertapenem; Female; Lactams; Mice; Mice, Inbred ICR; Muscular Diseases; Neutropenia; Protein Binding; Streptococcus pneumoniae; Survival Analysis | 2002 |
Pharmacodynamic profile of ertapenem against Klebsiella pneumoniae and Escherichia coli in a murine thigh model.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Colony Count, Microbial; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lactams; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Thigh | 2005 |
In vitro activity of MSI-78 alone and in combination with antibiotics against bacteria responsible for bloodstream infections in neutropenic patients.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteremia; Bacteria; beta-Lactams; Colistin; Colony Count, Microbial; Drug Therapy, Combination; Escherichia coli; Humans; Microbial Sensitivity Tests; Neutropenia; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis | 2005 |
Systematic reviews and meta-analysis of febrile neutropenia.
Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Therapy, Combination; Fever; Humans; Meta-Analysis as Topic; Neoplasms; Neutropenia; Reproducibility of Results; Review Literature as Topic; Treatment Outcome | 2005 |
Clinical guidelines for the management of cancer patients with neutropenia and unexplained fever.
Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Drug Therapy, Combination; Fever of Unknown Origin; Guidelines as Topic; Humans; Neoplasms; Neutropenia; Risk Factors; Treatment Outcome | 2005 |
Trough serum concentrations of beta-lactam antibiotics in cancer patients: inappropriateness of conventional schedules to pharmacokinetic/pharmacodynamic properties of beta-lactams.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Administration Schedule; Female; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutropenia; Prospective Studies | 2006 |
Neutropenia due to beta lactamine antibodies.
Topics: Agranulocytosis; Anti-Bacterial Agents; beta-Lactams; Humans; Immunoglobulin G; Neutropenia | 1984 |
Incidence of beta-lactam-induced delayed hypersensitivity and neutropenia during treatment of infective endocarditis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Drug Hypersensitivity; Endocarditis, Bacterial; Eosinophils; Female; Hemagglutination Tests; Hospitals, University; Humans; Hypersensitivity, Delayed; Incidence; Leukocyte Count; Male; Middle Aged; Neutropenia; Neutrophils; Penicillins; Prospective Studies | 1999 |
Comparative efficacy of different beta-lactam antibiotics and gentamicin in Klebsiella pneumoniae septicaemia in neutropenic mice.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Gentamicins; Klebsiella Infections; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Neutropenia; Sepsis | 1986 |
Measurement of specific IgG antibody levels in serum of patients on regimes comprising high total dose beta-lactam therapy.
Topics: Anemia, Hemolytic; Anti-Bacterial Agents; Antibody Specificity; beta-Lactams; Eosinophilia; Humans; Immunoglobulin G; Neutropenia; Penicillins; Radioimmunoassay | 1986 |
Double beta-lactam therapy in the immunocompromised host.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Drug Therapy, Combination; Humans; Immunosuppression Therapy; Neutropenia; Sepsis | 1985 |
Current needs for new beta-lactam antibiotics in pediatrics.
Topics: Abdomen; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Child, Preschool; Cystic Fibrosis; Fever; Humans; Infant; Infant, Newborn; Kinetics; Meningitis; Neutropenia | 1985 |