Page last updated: 2024-09-04

beta-lactams and Disease Models, Animal

beta-lactams has been researched along with Disease Models, Animal in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (7.25)	18.7374
1990's	7 (10.14)	18.2507
2000's	15 (21.74)	29.6817
2010's	38 (55.07)	24.3611
2020's	4 (5.80)	2.80

Authors

Authors	Studies
Arya, N; Dwivedi, J; Jagdale, AY; Jain, KS; Munde, MK	1
Arya, N; Coutinho, EC; Dwivedi, J; Jain, KS; Khedkar, VM	1
Artalejo, AR; Barahona, MV; de la Torre Martínez, R; Fernández-Ballester, G; Fernández-Carvajal, A; Ferrer-Montiel, A; González-Muñiz, R; González-Rodríguez, S; Martín-Escura, C; Medina-Peris, A; Olivos-Oré, LA; Spear, LA	1
Bar-David, E; Ben-Shmuel, A; Glinert, I; Kobiler, D; Levy, H; Schlomovitz, J; Sittner, A; Weiss, S	1
Arias, CA; Dinh, AQ; Kebriaei, R; Khan, A; Murray, BE; Rice, SA; Rybak, MJ; Singh, KV; Stamper, KC; Tran, TT	1
Balasubramanian, V; Basso, KB; Bharatham, N; Bonomo, RA; Boyce, JD; Bulitta, JB; Cadet, KC; Copik, AJ; Deveson Lucas, D; Dharuman, S; Drusano, GL; Fleischer, BA; Jiao, Y; Jimenez-Nieves, RH; Kim, TH; Landersdorfer, CB; Lang, Y; Lee, RE; Loudon-Hossler, V; Louie, A; LoVullo, ED; Mégroz, M; Moya, B; Norris, MH; Oyer, JL; Reeve, SM; Sayed, ARM; Schweizer, HP; Shah, NR; Shin, E; Soo Shin, B; Sutaria, DS; Tao, X; Tsuji, BT; Wallace, MJ; Werkman, C; Wright, A; Zhou, J	1
Bassetti, M; Brüggemann, RJ; Bulitta, JB; De Waele, JJ; Felton, TW; Friberg, LE; Marchand, S; Nielsen, EI; Ramos Martín, V; Roberts, JA; Tam, VH; Tängdén, T; Theuretzbacher, U; Tsuji, BT; Wareham, DW	1
Monogue, ML; Nicolau, DP	1
Rotondo, CM; Wright, GD	1
Bunk, B; Chakraborty, T; Doijad, SP; Falgenhauer, L; Goesmann, A; Gwozdzinski, K; Hain, T; Hegemann, JD; Imirzalioglu, C; Jaiswal, S; Mannala, GK; Marahiel, MA; Mraheil, MA; Mshana, SE; Overmann, J; Pati, NB; Ryan, D; Schultze, T; Spröer, C; Suar, M; Yao, Y	1
Barbier, F; Burdet, C; Decousser, JW; Lepeule, R; Ruppé, É; Woerther, PL	1
Alshehri, FS; Hakami, AY; Sari, Y	1
Andersson, DI; Linkevicius, M; Munck, C; Porse, A; Rosenkilde, CEH; Sommer, MOA	1
Bulman, ZP; Lenhard, JR	1
Barceló, IM; Jordana-Lluch, E; Juan, C; Oliver, A; Sánchez-Diener, I; Torrens, G; Zamorano, L	1
Crandon, JL; Hagihara, M; Nicolau, DP; Urban, C	1
Naisbitt, DJ; Uetrecht, J	1
Ahuja, V; Balasubramanian, V; Balganesh, M; Bhattacharjee, D; Dinesh, N; Ganguly, S; Kumar, N; Panduga, V; Parab, M; Ramachandran, V; Reddy, J; Shandil, R; Sharma, S; Solapure, S; Vishwas, KG	1
Crandon, JL; Nicolau, DP; Nordmann, P; Wiskirchen, DE	3
Alvarez-Rocha, L; Arias, J; Azanza, JR; Barberán, J; Candel, F; de Alarcón, CA; Fortún, J; García, JE; Gómez, J; Grau, S; Llinares, P; Marco, F; Maseda, E; Mensa, J; Montejo, M; Moreno, A; Parra, J; Pasquau, J; Picazo, J; Salavert, M; Soriano, A; Soy, D	1
Preet, S; Rishi, P; Singh, AP	1
Cabellos, C; Force, E; Garrigós, C; Pachón-Ibañez, ME; Taberner, F	1
Cao, Y; Ding, Z; Gong, Y; Jiang, H; Liu, X; Song, X; Wang, F; Wang, T; Wang, W; Zhang, N; Zhang, W; Zhang, Z	1
Angulo-Barturen, I; Arthur, M; Ballell, L; Barros-Aguirre, D; Dhar, N; Diacon, AH; García-Pérez, A; Hugonnet, JE; Lelievre, J; McKinney, JD; Rullas, J	1
Bradford, PA; Eakin, AE; Harris, JJ; Kim, A; McLaughlin, RE; O'Donnell, JP; Patey, S; Singh, R; Tanudra, MA	1
Hammer, E; Hildebrandt, O; Lindequist, U; Mikolasch, A; Schlüter, R; Witt, S	1
Chang, M; Ding, D; Janardhanan, J; Meisel, JE; Mobashery, S; Schroeder, VA; Wolter, WR	1
Kumaraswamy, M; Nizet, V; Olson, J; Pogliano, J; Quach, DT; Rybak, MJ; Sakoulas, G; Singh, NB; Yim, J	1
Bandiera, T; Bertozzi, F; Bertozzi, SM; Petracca, R; Piomelli, D; Ponzano, S; Sasso, O	1
Ishii, M; Matsumoto, Y; Moriya, K; Okazaki, M; Sato, T; Sekimizu, K; Tabuchi, F; Tatsuno, K	1
Choi, JY; Go, J; Kim, HJ; Lee, K; Lee, KM; Park, IH; Shin, JS; Yoon, SS	1
Ansaloni, L; Catena, F; Gazzotti, F; Nanetti, A; Nardo, B; Pezzilli, R; Pinna, AD; Santini, D	1
Ambrose, PG; Bassett, J; Beaudry, A; Bhavnani, SM; Critchley, I; Gill, SC; Heine, HS; Janjic, N; Li, J; Miller, L; Rubino, CM; Stone, KC	1
Balasubramanian, D; Jayawardena, SR; Kong, KF; Leal, SM; Mathee, K; Sautter, RT	1
Crandon, JL; Nicolau, DP	1
Armbruster, CE; Juneau, RA; Murrah, KA; Pang, B; Richardson, SH; Swords, WE; Weimer, KE	1
Buffé, C; Dalla Costa, T; de Araujo, BV; Diniz, A; Palma, EC	1
Breitbach, K; Eske-Pogodda, K; Harmer, NJ; Norville, IH; Sarkar-Tyson, M; Steinmetz, I; Titball, RW	1
Chau, F; Fantin, B; Le, P; Lefort, A; Lepeule, R; Massias, L; Nucci, A; Ruppé, E	1
Baryshnikova, A; Benton-Perdomo, L; Caron, A; Claveau, D; Daigneault, E; Deschamps, K; Elsen, NL; Gill, CJ; Kramer, S; Landry, F; Langlois, E; Lebeau-Jacob, C; Lee, SH; Liang, L; Lu, J; Lumb, KJ; Maxwell, E; Meredith, TC; Monteiro, JM; Parthasarathy, G; Pereira, PM; Petcu, M; Pinho, MG; Ramtohul, Y; Reid, JC; Roemer, T; Sharma, S; Sillaots, S; Skorey, K; Soisson, SM; Tam, J; Tan, CM; Therien, AG; Vaillancourt, J; Wang, H; Wang-Jarantow, L; Wong, S; Wu, J	1
Pan, X; Pei, Z; Qiu, W; Shi, Z; Wang, W; Wei, J; Xiao, G	1
Acosta, F; Cottagnoud, M; Cottagnoud, P; Pfister, M; Täuber, MG	1
Ariza, J; Ayats, J; Borraz, C; Cabellos, C; Corbella, X; Doménech, A; Gudiol, F; Montero, A; Tubau, F	1
Ariza, J; Cabellos, C; Domenech, A; Domínguez, MA; Gudiol, F; Liñares, J; Montero, A; Ribes, S	1
Ariza, J; Cabellos, C; Domenech, A; Domínguez, MA; Gudiol, F; Liñares, J; Montero, A; Ribes, S; Taberner, F; Tubau, F	1
Bishai, WR; Helke, K; Nuermberger, E	1
Beghi, E; Bendotti, C; Mennini, T	1
Hanaki, H; Hatano, K; Sunakawa, K; Yokota, Y	1
Barra, D; Bozzi, A; Cirioni, O; Di Giulio, A; Ghiselli, R; Giacometti, A; Luzi, C; Mangoni, ML; Mocchegiani, F; Orlando, F; Rinaldi, AC; Saba, V; Scalise, G; Silvestri, C	1
Cirioni, O; Della Vittoria, A; Ghiselli, R; Giacometti, A; Licci, A; Mocchegiani, F; Orlando, F; Saba, V; Scalise, G; Silvestri, C	1
Banevicius, MA; DeRyke, CA; Fan, HW; Nicolau, DP	1
Bast, DJ; De Azavedo, JC; Dresser, L; Duncan, CL; Low, DE; Walker, SE	1
Dalhoff, A; Gau, W; Gehl, AE; Lode, H	1
Brughera, M; Dayan, AD; Iatropoulos, MJ; Mazue, G; Newman, AJ; Scampini, G	1
Carbon, C; Farinotti, R; Goldstein, F; Gutmann, L; Mainardi, JL; Mohler, J; Zhou, XY	1
Matsuda, K; Matsumoto, S; Matsumoto, Y; Sasaki, H; Takasugi, H; Yoshida, Y	1
Fujikawa, T; Matsumoto, T; Miyazaki, S; Tateda, K; Yamaguchi, K	1
Aguilar, L; Casal, J; Fenoll, A; Giménez, MJ; Jado, I; Yuste, J	1
Aguilar, L; Casal, J; Fenoll, A; Giménez, MJ; Jado, I; Prieto, J; Yuste, J	1
Craig, WA; Ebert, SC	1
Craig, WA; Ebert, S; Fantin, B; Leggett, JE	1
Ashe, BM; Davies, P; Dellea, PS; Doherty, JB; Finke, PE; Fletcher, DS; Hagmann, W; Hand, KM; Mumford, RA; Osinga, DG	1
Abraham, SN; Baddour, LM; Christensen, GD; Hasty, DL; Josephs, JA; Lowrance, JH; Madison, BM; Parisi, JT; Simpson, WA	1
Bergogne-Berezin, E; Joly-Guillou, ML	1
Yogev, R	1
Pechère, JC	1
Bennett, DB; Comereski, CR; Williams, PD	1

Reviews

8 review(s) available for beta-lactams and Disease Models, Animal

Article	Year
The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections. Intensive care medicine, 2017, Volume: 43, Issue:7 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactams; Biomarkers; Critical Illness; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Monitoring; Glycopeptides; Humans; Intensive Care Units; Quinolones; Severity of Illness Index	2017
Inhibitors of metallo-β-lactamases. Current opinion in microbiology, 2017, Volume: 39 Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactams; Disease Models, Animal; Humans	2017
Carbapenems and alternative β-lactams for the treatment of infections due to extended-spectrum β-lactamase-producing Enterobacteriaceae: What impact on intestinal colonisation resistance? International journal of antimicrobial agents, 2018, Volume: 52, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Disease Models, Animal; Enterobacteriaceae; Enterobacteriaceae Infections; Gastrointestinal Microbiome; Humans	2018
Inoculum effect of β-lactam antibiotics. The Journal of antimicrobial chemotherapy, 2019, 10-01, Volume: 74, Issue:10 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactamases; beta-Lactams; Disease Models, Animal; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hydrolysis; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome	2019
Idiosyncratic adverse drug reactions: current concepts. Pharmacological reviews, 2013, Volume: 65, Issue:2 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cytokines; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Humans; Lymphocyte Activation; Risk Factors; Sulfonamides; T-Lymphocytes; Virus Diseases	2013
[Guidelines for antimicrobial treatment of the infection by Staphylococcus aureus]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2013, Volume: 26 Suppl 1 Topics: Acetamides; Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactams; Clindamycin; Daptomycin; Disease Models, Animal; Fluoroquinolones; Fosfomycin; Guidelines as Topic; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin	2013
Continuous infusion of beta-lactam antibiotics. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12 Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Disease Models, Animal; Humans; Infusions, Intravenous	1992
The role of beta-lactamase inhibitors in pediatrics. Advances in pediatric infectious diseases, 1988, Volume: 3 Topics: Animals; Anti-Bacterial Agents; Bacteria; beta-Lactams; Child; Child, Preschool; Clinical Trials as Topic; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Humans; Infections; Mice	1988

Trials

1 trial(s) available for beta-lactams and Disease Models, Animal

Article	Year
The role of beta-lactamase inhibitors in pediatrics. Advances in pediatric infectious diseases, 1988, Volume: 3 Topics: Animals; Anti-Bacterial Agents; Bacteria; beta-Lactams; Child; Child, Preschool; Clinical Trials as Topic; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Humans; Infections; Mice	1988

Other Studies

61 other study(ies) available for beta-lactams and Disease Models, Animal

Article	Year
Design, synthesis, and antihyperlipidemic evaluation of novel 2-[1-(substitutedphenyl)-4-oxo-azetidin-2-yl]-5,6-disubstitutedthieno[2,3-d]pyrimidin-4(3H)-ones. Archiv der Pharmazie, 2013, Volume: 346, Issue:8 Topics: Animals; Azetidines; Biomarkers; Cholesterol; Disease Models, Animal; Drug Design; Gemfibrozil; Hyperlipidemias; Hypolipidemic Agents; Intestinal Absorption; Intestinal Mucosa; Intestines; Molecular Structure; Polyethylene Glycols; Pyrimidinones; Rats; Rats, Wistar; Structure-Activity Relationship; Triglycerides	2013
Design, synthesis and biological evaluation of some 2-azetidinone derivatives as potential antihyperlipidemic agents. Archiv der Pharmazie, 2013, Volume: 346, Issue:12 Topics: Animals; Azetidines; Binding Sites; Biomarkers; Crystallography, X-Ray; Disease Models, Animal; Drug Design; Ezetimibe; Female; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Membrane Proteins; Membrane Transport Proteins; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Polyethylene Glycols; Protein Conformation; Rats; Rats, Wistar	2013
β-Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models. International journal of molecular sciences, 2022, Feb-28, Volume: 23, Issue:5 Topics: Analgesics; Animals; beta-Lactams; Cold Temperature; Disease Models, Animal; Ganglia, Spinal; Mice; Neuralgia; Rats; Sensory Receptor Cells; TRPM Cation Channels	2022
Using old antibiotics to treat ancient bacterium-β-lactams for Bacillus anthracis meningitis. PloS one, 2020, Volume: 15, Issue:2 Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Meropenem; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Rabbits; Sulbactam	2020
Mechanistic Insights Into the Differential Efficacy of Daptomycin Plus β-Lactam Combinations Against Daptomycin-Resistant Enterococcus faecium. The Journal of infectious diseases, 2020, 10-01, Volume: 222, Issue:9 Topics: Ampicillin; Animals; Anti-Bacterial Agents; beta-Lactams; Ceftaroline; Cephalosporins; Daptomycin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecium; Ertapenem; Gram-Positive Bacterial Infections; Microbial Sensitivity Tests; Rats; Sequence Alignment; Transcriptome	2020
Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling. Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:4 Topics: Animals; Bacteriological Techniques; beta-Lactams; Cell Membrane; Disease Models, Animal; Drug Discovery; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Humans; Models, Theoretical; Penicillin-Binding Proteins	2021
Translational Efficacy of Humanized Exposures of Cefepime, Ertapenem, and Levofloxacin against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Complicated Urinary Tract Infection. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:11 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Disease Models, Animal; Ertapenem; Escherichia coli Infections; Female; Humans; Levofloxacin; Mice, Inbred ICR; Microbial Sensitivity Tests; Urinary Tract Infections; Uropathogenic Escherichia coli	2017
Enterobacter bugandensis: a novel enterobacterial species associated with severe clinical infection. Scientific reports, 2018, 03-29, Volume: 8, Issue:1 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cytokines; Disease Models, Animal; Drug Resistance, Bacterial; Enterobacter; Enterobacteriaceae Infections; Genome, Bacterial; Humans; Mice; O Antigens; Plasmids; Survival Rate; Transcriptome; Virulence	2018
β-lactams modulate astroglial glutamate transporters and attenuate dependence to CP 55,940, a CB1 receptor agonist, in rat model. Behavioural brain research, 2019, 02-01, Volume: 359 Topics: Amino Acid Transport System X-AG; Ampicillin; Animals; Astrocytes; beta-Lactams; Brain; Cannabinoid Receptor Agonists; Central Nervous System Agents; Cyclohexanols; Disease Models, Animal; Drug-Seeking Behavior; Gene Expression; Male; Rats; Receptor, Cannabinoid, CB1; Substance-Related Disorders; Sulbactam	2019
Collateral sensitivity constrains resistance evolution of the CTX-M-15 β-lactamase. Nature communications, 2019, 02-06, Volume: 10, Issue:1 Topics: Amdinocillin; Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefotaxime; Disease Models, Animal; Drug Combinations; Drug Resistance, Microbial; Escherichia coli; Female; Gene Transfer, Horizontal; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mutation	2019
In Vivo Validation of Peptidoglycan Recycling as a Target to Disable AmpC-Mediated Resistance and Reduce Virulence Enhancing the Cell-Wall-Targeting Immunity. The Journal of infectious diseases, 2019, 10-22, Volume: 220, Issue:11 Topics: Animals; Bacteremia; Bacterial Load; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Ceftazidime; Cell Wall; Disease Models, Animal; Female; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Peptidoglycan; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Survival Analysis; Treatment Outcome; Virulence	2019
Efficacy of doripenem and ertapenem against KPC-2-producing and non-KPC-producing Klebsiella pneumoniae with similar MICs. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:7 Topics: Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; Disease Models, Animal; Doripenem; Ertapenem; Klebsiella Infections; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Treatment Outcome	2013
In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; beta-Lactams; Clavulanic Acid; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Meropenem; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Streptomycin; Thienamycins; Treatment Outcome; Tuberculosis, Pulmonary	2013
Efficacy of humanized carbapenem exposures against New Delhi metallo-β-lactamase (NDM-1)-producing enterobacteriaceae in a murine infection model. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactamases; beta-Lactams; Carbapenems; Disease Models, Animal; Doripenem; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ertapenem; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Time Factors	2013
In vivo efficacy of human simulated regimens of carbapenems and comparator agents against NDM-1-producing Enterobacteriaceae. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3 Topics: Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Disease Models, Animal; Doripenem; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Humans; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests	2014
Efficacy of humanized carbapenem and ceftazidime regimens against Enterobacteriaceae producing OXA-48 carbapenemase in a murine infection model. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3 Topics: Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Ceftazidime; Disease Models, Animal; Doripenem; Ertapenem; Humans; Klebsiella pneumoniae; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests	2014
Nisin/β-lactam adjunct therapy against Salmonella enterica serovar Typhimurium: a mechanistic approach. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:7 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cell Membrane; Disease Models, Animal; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Immunologic Factors; Liver; Metabolic Networks and Pathways; Mice, Inbred BALB C; Nisin; Permeability; Salmonella Infections, Animal; Salmonella typhimurium	2014
Experimental study of the efficacy of linezolid alone and in combinations against experimental meningitis due to Staphylococcus aureus strains with decreased susceptibility to beta-lactams and glycopeptides. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014, Volume: 20, Issue:9 Topics: Acetamides; Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Glycopeptides; Linezolid; Meningitis, Bacterial; Microbial Sensitivity Tests; Oxazolidinones; Rabbits; Random Allocation; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin	2014
Efficacy of cefepime, ertapenem and norfloxacin against leptospirosis and for the clearance of pathogens in a hamster model. Microbial pathogenesis, 2014, Volume: 77 Topics: Animal Structures; Animals; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Ertapenem; Histocytochemistry; Leptospira interrogans serovar autumnalis; Leptospirosis; Norfloxacin; Survival Analysis; Treatment Outcome	2014
Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Dipeptidases; Disease Models, Animal; Drug Therapy, Combination; GPI-Linked Proteins; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Respiratory Tract Infections; Staphylococcal Infections; Tuberculosis	2015
Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam. The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:9 Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; beta-Lactams; Disease Models, Animal; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Mice; Microbial Sensitivity Tests; Models, Biological; Treatment Outcome	2015
Targeted synthesis of novel β-lactam antibiotics by laccase-catalyzed reaction of aromatic substrates selected by pre-testing for their antimicrobial and cytotoxic activity. Applied microbiology and biotechnology, 2016, Volume: 100, Issue:11 Topics: Animals; Anti-Infective Agents; beta-Lactamases; beta-Lactams; Biotransformation; Catalysis; Cephalosporins; Culture Media; Disease Models, Animal; Enterococcus; Female; Gram-Positive Bacteria; Hydroquinones; Industrial Microbiology; Laccase; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Penicillins; Staphylococcal Infections; Staphylococcus	2016
In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with β-Lactams. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Disease Models, Animal; Drug Synergism; Female; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Oxacillin; Oxadiazoles; Staphylococcal Infections	2016
Cefazolin and Ertapenem, a Synergistic Combination Used To Clear Persistent Staphylococcus aureus Bacteremia. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: Aged, 80 and over; Animals; Anti-Bacterial Agents; Bacteremia; beta-Lactams; Cefazolin; Disease Models, Animal; Disk Diffusion Antimicrobial Tests; Drug Synergism; Drug Therapy, Combination; Ertapenem; Female; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Staphylococcal Infections; Staphylococcal Skin Infections	2016
Progress in the development of β-lactams as N-Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N-O-substituted derivatives. European journal of medicinal chemistry, 2017, Jan-27, Volume: 126 Topics: Amidohydrolases; Animals; beta-Lactams; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Humans; Inflammation; Mice; Pain; Structure-Activity Relationship	2017
Synergistic effects of vancomycin and β-lactams against vancomycin highly resistant Staphylococcus aureus. The Journal of antibiotics, 2017, Volume: 70, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Bombyx; Ceftriaxone; Disease Models, Animal; Drug Synergism; Microbial Sensitivity Tests; Oxacillin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance	2017
A Genetic Screen Reveals Novel Targets to Render Frontiers in cellular and infection microbiology, 2017, Volume: 7 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Caenorhabditis elegans; Cell Wall; Disease Models, Animal; DNA Transposable Elements; Gene Knockout Techniques; Genetic Complementation Test; Genetic Testing; Mice, Inbred C57BL; Microbial Viability; Muramidase; Mutagenesis, Insertional; Pseudomonas aeruginosa; Pseudomonas Infections; Vancomycin; Virulence	2017
Effect of early antibiotic prophylaxis with ertapenem and meropenem in experimental acute pancreatitis in rats. Journal of hepato-biliary-pancreatic surgery, 2009, Volume: 16, Issue:3 Topics: Animals; Antibiotic Prophylaxis; Bacterial Infections; beta-Lactams; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ertapenem; Male; Meropenem; Pancreatitis, Acute Necrotizing; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Thienamycins	2009
Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; beta-Lactamases; beta-Lactams; Blood Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inhalation Exposure; Mice; Mice, Inbred BALB C; Models, Biological	2010
Co-regulation of {beta}-lactam resistance, alginate production and quorum sensing in Pseudomonas aeruginosa. Journal of medical microbiology, 2011, Volume: 60, Issue:Pt 2 Topics: Alginates; Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Caenorhabditis elegans; Disease Models, Animal; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Glucuronic Acid; Hexuronic Acids; Promoter Regions, Genetic; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Sigma Factor; Virulence; Virulence Factors	2011
Pharmacodynamic approaches to optimizing beta-lactam therapy. Critical care clinics, 2011, Volume: 27, Issue:1 Topics: Adult; Animals; Anti-Bacterial Agents; beta-Lactams; Child; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intravenous; Kidney; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Thienamycins; Time Factors	2011
Divergent mechanisms for passive pneumococcal resistance to β-lactam antibiotics in the presence of Haemophilus influenzae. The Journal of infectious diseases, 2011, Feb-15, Volume: 203, Issue:4 Topics: Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Biofilms; Chinchilla; Disease Models, Animal; Haemophilus Infections; Haemophilus influenzae; Microbial Viability; Otitis Media; Pneumococcal Infections; Streptococcus pneumoniae	2011
PK-PD modeling of β-lactam antibiotics: in vitro or in vivo models? The Journal of antibiotics, 2011, Volume: 64, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Immunocompromised Host; Male; Models, Biological; Piperacillin; Rats; Rats, Wistar	2011
A novel FK-506-binding-like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei. Microbiology (Reading, England), 2011, Volume: 157, Issue:Pt 9 Topics: Amino Acid Sequence; Animals; Bacterial Proteins; beta-Lactams; Burkholderia pseudomallei; Disease Models, Animal; Enzyme Activation; Female; HeLa Cells; Humans; Melioidosis; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mutation; Peptidylprolyl Isomerase; Protein Conformation; Recombinant Proteins; Sequence Alignment; Tacrolimus Binding Proteins; Virulence	2011
Cefoxitin as an alternative to carbapenems in a murine model of urinary tract infection due to Escherichia coli harboring CTX-M-15-type extended-spectrum β-lactamase. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactamases; beta-Lactams; Carbapenems; Cefoxitin; Ceftriaxone; Conjugation, Genetic; Disease Models, Animal; Drug Administration Schedule; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Humans; Imipenem; Kidney; Mice; Microbial Sensitivity Tests; Mutation Rate; Plasmids; Urinary Bladder; Urinary Tract Infections	2012
Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics. Science translational medicine, 2012, Mar-21, Volume: 4, Issue:126 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Cell Division; Crystallography, X-Ray; Cytoskeletal Proteins; Disease Models, Animal; Drug Resistance, Bacterial; Drug Synergism; Gene Regulatory Networks; Guanosine Diphosphate; Imipenem; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Mutation; Protein Structure, Secondary; Protein Transport; Pyridines; Staphylococcal Infections; Thiazoles; Virulence	2012
The beta-lactam antibiotic, ceftriaxone, provides neuroprotective potential via anti-excitotoxicity and anti-inflammation response in a rat model of traumatic brain injury. The journal of trauma and acute care surgery, 2012, Volume: 73, Issue:3 Topics: Analysis of Variance; Animals; beta-Lactams; Biopsy, Needle; Blotting, Western; Brain Edema; Brain Injuries; Ceftriaxone; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Transporter 2; Immunohistochemistry; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Survival Rate; Treatment Outcome; Up-Regulation	2012
Activities of ertapenem, a new long-acting carbapenem, against penicillin-sensitive or -resistant pneumococci in experimental meningitis. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Ceftriaxone; Disease Models, Animal; Ertapenem; Lactams; Meningitis, Pneumococcal; Penicillin Resistance; Rabbits; Streptococcus pneumoniae; Vancomycin	2003
Antibiotic combinations for serious infections caused by carbapenem-resistant Acinetobacter baumannii in a mouse pneumonia model. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:6 Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Colistin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia, Bacterial; Rifampin; Tobramycin	2004
A mouse peritonitis model for the study of glycopeptide efficacy in GISA infections. Microbial drug resistance (Larchmont, N.Y.), 2004,Winter, Volume: 10, Issue:4 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Glycopeptides; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Peritonitis; Staphylococcal Infections; Staphylococcus aureus	2004
Experimental study on the efficacy of combinations of glycopeptides and beta-lactams against Staphylococcus aureus with reduced susceptibility to glycopeptides. The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:4 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Glycopeptides; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Peritonitis; Staphylococcal Infections; Staphylococcus aureus; Time Factors	2005
Low-dose aerosol model of pneumococcal pneumonia in the mouse: utility for evaluation of antimicrobial efficacy. International journal of antimicrobial agents, 2005, Volume: 26, Issue:6 Topics: Aerosols; Animals; Anti-Bacterial Agents; beta-Lactams; Disease Models, Animal; Drug Resistance, Bacterial; Ertapenem; Female; Mice; Mice, Inbred CBA; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae	2005
New ideas for therapy in ALS: critical considerations. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2006, Volume: 7, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; beta-Lactams; Ceftriaxone; Cephalosporins; Clinical Trials as Topic; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Humans; Mice; Mice, Transgenic	2006
[Combined effect of vancomycin or teicoplanin plus a beta-lactam antibiotic in mouse infection models caused by beta-lactam antibiotec-induced vancomycin resistant MRSA (BIVR)]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2006, Volume: 80, Issue:3 Topics: Animals; beta-Lactams; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Male; Methicillin Resistance; Mice; Mice, Inbred ICR; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin	2006
Interaction of antimicrobial peptide temporin L with lipopolysaccharide in vitro and in experimental rat models of septic shock caused by gram-negative bacteria. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:7 Topics: Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; beta-Lactams; Disease Models, Animal; Drug Therapy, Combination; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Lipopolysaccharides; Male; Microbial Sensitivity Tests; Peritonitis; Piperacillin; Proteins; Rats; Rats, Wistar; Shock, Septic	2006
The cathelicidin-derived tritrpticin enhances the efficacy of ertapenem in experimental rat models of septic shock. Shock (Augusta, Ga.), 2006, Volume: 26, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; beta-Lactams; Cathelicidins; Cecum; Disease Models, Animal; Drug Synergism; Endotoxins; Enterococcus faecalis; Ertapenem; Escherichia coli; Escherichia coli Infections; Interleukin-6; Ligation; Male; Microbial Sensitivity Tests; Oligopeptides; Rats; Rats, Wistar; Shock, Septic; Tumor Necrosis Factor-alpha	2006
Bactericidal activities of meropenem and ertapenem against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a neutropenic mouse thigh model. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4 Topics: Animals; beta-Lactamases; beta-Lactams; Disease Models, Animal; Ertapenem; Escherichia coli; Escherichia coli Infections; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Mice; Microbial Sensitivity Tests; Thienamycins	2007
Antipneumococcal activity of ertapenem compared with gatifloxacin in a temperature-sensitive murine model of acute pneumonia. Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:4 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Disease Models, Animal; DNA Topoisomerase IV; Ertapenem; Fluoroquinolones; Gatifloxacin; Mice; Mice, Inbred Strains; Mutation; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Temperature; Treatment Outcome	2007
Pharmacokinetics and antibacterial efficacy in vivo of beta-lactam combinations against Proteus vulgaris. Chemotherapy, 1982, Volume: 28, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Biological Availability; Disease Models, Animal; Drug Therapy, Combination; Enzyme Induction; Exudates and Transudates; Female; Kinetics; Proteus Infections; Proteus vulgaris; Rats; Rats, Inbred Strains	1982
Urinary bladder hyperplasia in the rat: non-specific pathogenetic considerations using a beta-lactam antibiotic. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:4-5 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Hyperplasia; Kidney; Lactams; Male; Precancerous Conditions; Rats; Time Factors; Urinary Bladder; Urinary Bladder Diseases; Urinary Bladder Neoplasms; Urine	1994
Activity of isepamicin and selection of permeability mutants to beta-lactams during aminoglycoside therapy of experimental endocarditis due to Klebsiella pneumoniae CF104 producing an aminoglycoside acetyltransferase 6' modifying enzyme and a TEM-3 beta-l The Journal of infectious diseases, 1994, Volume: 169, Issue:6 Topics: Acetyltransferases; Amikacin; Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactamases; beta-Lactams; Cell Membrane Permeability; Disease Models, Animal; Drug Therapy, Combination; Endocarditis; Female; Gentamicins; Klebsiella pneumoniae; Mutation; Rabbits	1994
Synthesis and anti-Helicobacter pylori activity of FR182024, a new cephem derivative. Bioorganic & medicinal chemistry letters, 1999, Nov-01, Volume: 9, Issue:21 Topics: Amoxicillin; Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Clarithromycin; Disease Models, Animal; Helicobacter pylori; Lactams; Mice; Molecular Structure	1999
Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:3 Topics: Animals; Anti-Bacterial Agents; Azithromycin; beta-Lactams; Bronchopneumonia; Clarithromycin; Disease Models, Animal; Haemophilus Infections; Haemophilus influenzae; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Treatment Outcome	2001
Beta-lactam modification of the bacteraemic profile and its relationship with mortality in a pneumococcal mouse sepsis model. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:2 Topics: Animals; Anti-Bacterial Agents; Bacteremia; beta-Lactams; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pneumococcal Infections; Sepsis	2002
Effects of specific antibodies against Streptococcus pneumoniae on pharmacodynamic parameters of beta-lactams in a mouse sepsis model. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:5 Topics: Amoxicillin; Animals; Antibodies, Bacterial; Antibody Specificity; beta-Lactams; Cefotaxime; Disease Models, Animal; Humans; Immune Sera; Mice; Mice, Inbred BALB C; Pneumococcal Infections; Sepsis; Streptococcus pneumoniae; Treatment Outcome	2002
Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models. Scandinavian journal of infectious diseases. Supplementum, 1990, Volume: 74 Topics: 4-Quinolones; Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; beta-Lactams; Disease Models, Animal; Dose-Response Relationship, Drug; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Gram-Negative Bacteria; Least-Squares Analysis; Mice; Mice, Inbred ICR; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Specific Pathogen-Free Organisms	1990
A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster. The American review of respiratory disease, 1990, Volume: 141, Issue:3 Topics: alpha 1-Antitrypsin; Amino Acid Chloromethyl Ketones; Animals; Anti-Bacterial Agents; beta-Lactams; Bronchoalveolar Lavage Fluid; Cricetinae; Disease Models, Animal; Hemorrhage; Humans; Instillation, Drug; Lung Diseases; Male; Mesocricetus; Neutrophils; Pancreatic Elastase; Thermolysin; Trachea	1990
Colonial morphology of staphylococci on Memphis agar: phase variation of slime production, resistance to beta-lactam antibiotics, and virulence. The Journal of infectious diseases, 1990, Volume: 161, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Culture Media; Disease Models, Animal; Drug Resistance, Microbial; Endocarditis, Bacterial; Male; Mice; Microscopy, Electron; Mutation; Phagocytosis; Phenotype; Rats; Rats, Inbred Strains; Staphylococcal Infections; Staphylococcus; Staphylococcus epidermidis; Urinary Tract Infections; Virulence	1990
[Synergism or antagonism in combinations of beta-lactam antibiotics]. Presse medicale (Paris, France : 1983), 1986, May-31, Volume: 15, Issue:22 Topics: Animals; Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Humans	1986
Emergence of resistance during beta-lactam therapy of gram-negative infections. Bacterial mechanisms and medical responses. Drugs, 1988, Volume: 35 Suppl 2 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carrier Proteins; Cell Membrane Permeability; Disease Models, Animal; Drug Resistance, Microbial; Enzyme Induction; Gram-Negative Bacteria; Hexosyltransferases; Mice; Mice, Inbred ICR; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Peritonitis	1988
Animal model for evaluating the convulsive liability of beta-lactam antibiotics. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding, Competitive; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Disease Models, Animal; Drug Combinations; gamma-Aminobutyric Acid; Imipenem; Lactams; Male; Mice; Pentylenetetrazole; Seizures; Thienamycins	1988