Page last updated: 2024-09-04

beta-lactams and Cystic Fibrosis

beta-lactams has been researched along with Cystic Fibrosis in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (13.89)	18.7374
1990's	11 (15.28)	18.2507
2000's	6 (8.33)	29.6817
2010's	35 (48.61)	24.3611
2020's	10 (13.89)	2.80

Authors

Authors	Studies
Cocuzza, CE; Galletti, P; Giacomini, D; Musumeci, R; Pori, M; Quintavalla, A	1
Dogru, D; Emiralioglu, N; Kiper, N; Ozcelik, U; Sahiner, UM; Sekerel, BE; Soyer, O; Tugcu, GD; Yalcin, E	1
Flume, PA; Goss, CH; Heltshe, SL; Sanders, DB; Skalland, M; VanDevanter, DR; West, NE	1
Brockow, K; de Monestrol, I; Gülen, T; Kowalik, A; Sorjonen, K	1
Burrell, A; Chaney, H; Crandall, KA; Freishtat, RJ; Hahn, A; Koumbourlis, AC; Sami, I; Zemanick, ET	1
Chiarelli, LR; Degiacomi, G; Gutierrez, DL; Pasca, MR; Recchia, D; Stamilla, A; Stelitano, G	1
Braun, C; Durieu, I; Durupt, S; Jubin, V; Mainguy, C; Nicolas, JF; Nosbaum, A; Nove-Josserand, R; Ohlmann, C; Reix, P	1
Flanagan, JN; Kavanaugh, LG; Steck, TR	1
Abdul-Aziz, MH; Portunato, F; Roberts, JA	1
Burrell, A; Chaney, H; Crandall, KA; Freishtat, RJ; Hahn, A; Koumbourlis, AC; Louie, S; Sami, I; Zemanick, ET	1
Holland, P; Jahnke, N	1
Bhatt, J; Nevitt, SJ; Smyth, AR	1
Calaresu, E; Cocuzza, CE; Giacomini, D; Martelli, G; Musumeci, R; Piccichè, M	1
Deka, R; Hong, LT; King, JB; Liou, TG; Stevens, V; Young, DC	1
Bulitta, JB; Drescher, SK; Drusano, GL; Jiao, Y; Landersdorfer, CB; Louie, A; Moya, B; Oliver, A; Shin, BS; Sörgel, F; Tao, X; Tsuji, BT; Wittau, M; Zavascki, AP	1
Compain, F; Grohs, P; Mathy, V	1
Floch, P; Gaudru, C; Guet-Revillet, H; Massip, C; Mathieu, C; Miaut, V; Oswald, E; Segonds, C	1
Fluit, AC; Franssens, BT; Rentenaar, RJ	1
Clark, ST; Coburn, B; Donaldson, SL; Guttman, DS; Hwang, DM; Sinha, U; Tullis, DE; Wang, PW; Waters, VJ; Yau, YCW; Zhang, Y	1
Bost, JE; Chaney, H; Crandall, KA; Fanous, H; Freishtat, RJ; Hahn, A; Jensen, C; Koumbourlis, AC; Louie, S; Perez, GF; Sami, I; van den Anker, JN; Zemanick, ET	1
Castells, MC; Foer, D; Marquis, K; Romero, N	1
Barbosa, C; Bewig, B; Bobis, I; Fickenscher, H; Franke, A; Friedrichs, A; Höppner, M; Krenz-Weinreich, A; Rosenstiel, P; Rühlemann, M; Schreiber, S; Schubert, S; Schulenburg, H; Tueffers, L	1
Cavallo, JD; Fichant, G; Llanes, C; Mérens, A; Plésiat, P; Pourcel, C; Richardot, C	1
El-Ghaiesh, S; Farrell, J; Hamlett, J; Jenkins, RE; Meng, X; Monshi, MM; Naisbitt, DJ; Park, BK; Peckham, D; Pirmohamed, M; Sanderson, JP; Whitaker, P; Yaseen, FS	1
de Blic, J; Le Bourgeois, M; Matar, R; Ponvert, C; Scheinmann, P	1
Elphick, HE; Jahnke, N	1
Armoni, S; Breuer, O; Cohen-Cymberknoh, M; Kerem, E; Shoseyov, D	1
Falagas, ME; Trigkidis, KK; Vardakas, KZ	1
Cies, JJ; Kuti, JL; Lapin, C; Muhlebach, MS; Neu, N; Nguyen, ST; Nicolau, DP; Novak, KJ; Pettit, RS; Saiman, L	1
Fischer, DR; Namanny, H; Zobell, JT	1
Elborn, JS; Gilpin, DF; Hatch, J; McGrath, SJ; McIlreavey, L; Muhlebach, MS; Sherrard, LJ; Tunney, MM; Wolfgang, MC	1
Burgess, DR; Burgess, DS; Martin, CA; Rutter, WC; Thompson, RZ	1
Abdel-Haq, N; Ang, JY; Nicolau, DP; Satlin, MJ; Thabit, AK; van Duin, D; Zhu, F	1
Elphick, HE; Scott, A	1
Attrée, I; Ducruix, A; El Garch, F; Llanes, C; Muller, C; Phan, G; Plésiat, P; Vettoretti, L	1
Boersma, WG; van der Eerden, MM	1
Flume, PA; Goss, CH; Kuhn, RJ; Marshall, BC; Mogayzel, PJ; Robinson, KA; Rosenblatt, RL	1
Amenomori, M; Fujita, H; Hara, A; Izumikawa, K; Kakeya, H; Kohno, S; Miyazaki, T; Nagayasu, T; Sakamoto, N; Seki, M; Tagawa, T; Takasaki, K; Tsuchiya, T; Yamamoto, Y; Yamasaki, N; Yanagihara, K	1
Ampofo, K; Cash, J; Chatfield, BA; Marshall, BC; Olson, J; Waters, CD; Young, DC; Zobell, JT	1
Kirkpatrick, CM; Lipman, J; Mohd Hafiz, AA; Roberts, JA; Staatz, CE	1
Hayes, D; Mansour, HM	1
Antunes, AL; Barth, AL; Freitas, AL; Perez, LR	1
Bhatt, J; Smyth, AR	1
El-Ghaiesh, S; Elsheikh, A; Farrell, J; French, N; Jenkins, R; Meng, X; Monshi, MM; Naisbitt, DJ; Park, BK; Peckham, D; Pirmohamed, M; Whitaker, P	1
Ciofu, O; Høiby, N; Mandsberg, LF; Wang, H	1
Chatfield, BA; Young, DC; Zobell, JT	1
Chao, C; Nair, CG; Ryall, B; Williams, HD	1
Jain, M; Prickett, M	1
Burns, JL; Emerson, JC; Foster, JM; Gibson, RL; Moskowitz, SM	1
Bell, SC; Burrows, JA; Kirkpatrick, CM; Nissen, LM	1
Anstead, MI; Hayes, D; Kanga, JF; Kuhn, RJ	1
Neu, HC; Prince, AS	1
Bryan, LE; Godfrey, AJ; Rabin, HR	1
Marks, MI; Scribner, RK; Tarpay, MM; Weber, AH; Welch, DF	1
Corkill, JE; Deveney, J; Hart, CA; Heaf, D; Pratt, J; Shears, P; Smyth, A	1
Cahen, P; Coustère, C; de Blic, J; Delacourt, C; Gaillard, JL; Le Bourgeois, M; Lenoir, G; Scheinmann, P; Silly, C	1
Ciofu, O; Giwercman, B; Høiby, N; Pedersen, SS; Pressler, T; Walter-Rasmussen, J	1
Pleasants, RA; Samuelson, WM; Walker, TR	1
Cheng, K; Denning, N; Doherty, C; Govan, JR; Hart, CA; Heaf, DP; Smyth, RL; van Saene, H; Winstanley, C	1
Ciofu, O; Giwercman, B; Høiby, N; Pedersen, SS; Petersen, TD; Pressler, T	1
Brownlee, KG; Conway, SP; Denton, M; Littlewood, JM; Todd, NJ	1
Denton, M; Hawkey, PM; Keer, V	1
Giwercman, B; Høiby, N; Lambert, PA; Meyer, C; Reinert, C	1
Gordon, CA; Hodges, NA	1
Basker, M; Bolister, N; Hodges, NA; Marriott, C	1
Croize, J; Gout, JP; Le Noc, P; Robert, J	1
Aronoff, SC	1
Lietman, PS	1
Böwing, HB; Dominick, HC; Geldmacher von Mallinckrodt, M; Gottschalk, B; Rey, M; Sörgel, F; Stehr, C; Stephan, U; Wiesemann, HG	1
Earl, HS; Sullivan, TJ	1
Maki, DG; Nichols, L	1
Nelson, JD	1

Reviews

14 review(s) available for beta-lactams and Cystic Fibrosis

Article	Year
The controversy of drug hypersensitivity in patients with cystic fibrosis and review of the literature. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2022, Volume: 33, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Child; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Male; Skin Tests	2022
International journal of molecular sciences, 2023, Feb-27, Volume: 24, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Mycobacterium abscessus; Mycobacterium Infections, Nontuberculous	2023
Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base. Current opinion in infectious diseases, 2020, Volume: 33, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Critical Illness; Cystic Fibrosis; Drug Monitoring; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Infusions, Intravenous; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections; Severity of Illness Index	2020
Single versus combination intravenous anti-pseudomonal antibiotic therapy for people with cystic fibrosis. The Cochrane database of systematic reviews, 2021, 06-23, Volume: 6 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cephalosporins; Child; Cystic Fibrosis; Drug Therapy, Combination; Humans; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections	2021
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2017, 03-27, Volume: 3 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Body Mass Index; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Vital Capacity; Young Adult	2017
Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis. Clinical pharmacokinetics, 2019, Volume: 58, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Humans	2019
Single versus combination intravenous antibiotic therapy for people with cystic fibrosis. The Cochrane database of systematic reviews, 2014, Apr-30, Issue:4 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Humans; Injections, Intravenous; Randomized Controlled Trials as Topic; Respiratory Tract Infections	2014
Inhaled antibiotics beyond aminoglycosides, polymyxins and aztreonam: A systematic review. International journal of antimicrobial agents, 2015, Volume: 45, Issue:3 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Bronchiectasis; Cystic Fibrosis; Fosfomycin; Humans; Pneumonia, Ventilator-Associated; Quinolones; Respiratory Tract Infections; Treatment Outcome	2015
Single versus combination intravenous anti-pseudomonal antibiotic therapy for people with cystic fibrosis. The Cochrane database of systematic reviews, 2016, 12-01, Volume: 12 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Humans; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections	2016
Cystic fibrosis pulmonary guidelines: treatment of pulmonary exacerbations. American journal of respiratory and critical care medicine, 2009, Nov-01, Volume: 180, Issue:9 Topics: Adrenal Cortex Hormones; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Drug Synergism; Humans; Respiratory Therapy	2009
Continuous infusion vs. bolus dosing: implications for beta-lactam antibiotics. Minerva anestesiologica, 2012, Volume: 78, Issue:1 Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Child; Critical Care; Critical Illness; Cystic Fibrosis; Fever; Humans; Infusions, Intravenous; Length of Stay; Leukocyte Count; Neoplasms; Respiration, Artificial; Treatment Outcome	2012
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2012, Feb-15, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intravenous; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2012
Phenotypes selected during chronic lung infection in cystic fibrosis patients: implications for the treatment of Pseudomonas aeruginosa biofilm infections. FEMS immunology and medical microbiology, 2012, Volume: 65, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Biofilms; Chronic Disease; Cystic Fibrosis; Humans; Lung; Phenotype; Pseudomonas aeruginosa; Pseudomonas Infections; Selection, Genetic	2012
High dose treatment with antibiotics in cystic fibrosis--a reappraisal with special reference to the pharmacokinetics of beta-lactams and new fluoroquinolones in adult CF-patients. Infection, 1987, Volume: 15, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Humans; Quinolines	1987

Trials

2 trial(s) available for beta-lactams and Cystic Fibrosis

Article	Year
Correlation between activity of beta-lactam agents in vitro and bacteriological outcome in acute pulmonary exacerbations of cystic fibrosis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1995, Volume: 14, Issue:4 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Infant; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Respiratory Tract Infections; Serum Bactericidal Test; Sputum; Treatment Outcome	1995
Pharmacokinetics of antimicrobial drugs in cystic fibrosis. Beta-lactam antibiotics. Chest, 1988, Volume: 94, Issue:2 Suppl Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Child; Clinical Trials as Topic; Cystic Fibrosis; Humans; Infant, Newborn; Lung Diseases; Respiratory Tract Infections	1988

Article

Year

Correlation between activity of beta-lactam agents in vitro and bacteriological outcome in acute pulmonary exacerbations of cystic fibrosis.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1995, Volume: 14, Issue:4

Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Infant; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Respiratory Tract Infections; Serum Bactericidal Test; Sputum; Treatment Outcome

1995

Pharmacokinetics of antimicrobial drugs in cystic fibrosis. Beta-lactam antibiotics.

Chest, 1988, Volume: 94, Issue:2 Suppl

Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Child; Clinical Trials as Topic; Cystic Fibrosis; Humans; Infant, Newborn; Lung Diseases; Respiratory Tract Infections

1988

Other Studies

56 other study(ies) available for beta-lactams and Cystic Fibrosis

Article	Year
Antibacterial agents and cystic fibrosis: synthesis and antimicrobial evaluation of a series of N-thiomethylazetidinones. ChemMedChem, 2011, Oct-04, Volume: 6, Issue:10 Topics: Anti-Bacterial Agents; Azetidines; Cystic Fibrosis; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests	2011
Antipseudomonal treatment decisions during CF exacerbation management. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2022, Volume: 21, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Female; Fluoroquinolones; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies	2022
Antibiotic hypersensitivity in cystic fibrosis - Low frequency of anaphylaxis over 16 000 courses. British journal of clinical pharmacology, 2022, Volume: 88, Issue:11 Topics: Adult; Anaphylaxis; Anti-Bacterial Agents; beta-Lactams; Child; Cystic Fibrosis; Drug Hypersensitivity; Humans; Piperacillin; Retrospective Studies	2022
Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with reductions in microbial richness and diversity in persons with cystic fibrosis. Scientific reports, 2023, 01-21, Volume: 13, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Child; Cystic Fibrosis; Humans; Lung	2023
The diagnosis of hypersensitivity to antibiotics is rarely confirmed by allergy work-up in cystic fibrosis patients. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2020, Volume: 31, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactams; Child; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Male; Prevalence; Retrospective Studies; Risk Factors; Skin Tests; Young Adult	2020
Reciprocal antibiotic collateral sensitivity in Burkholderia multivorans. International journal of antimicrobial agents, 2020, Volume: 56, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactams; Burkholderia; Burkholderia Infections; Cystic Fibrosis; Drug Collateral Sensitivity; Drug Resistance, Bacterial; Genome, Bacterial; Humans; Lung; Microbial Sensitivity Tests; Whole Genome Sequencing	2020
Importance of beta-lactam pharmacokinetics and pharmacodynamics on the recovery of microbial diversity in the airway of persons with cystic fibrosis. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2021, Volume: 69, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactams; Child; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Microbiota; Prospective Studies; Respiratory System	2021
Design and Synthesis of 4-Alkylidene-β-lactams: Benzyl- and Phenethyl-carbamates as Key Fragments to Switch on Antibacterial Activity. ChemMedChem, 2017, 09-21, Volume: 12, Issue:18 Topics: Anti-Bacterial Agents; beta-Lactams; Carbamates; Cystic Fibrosis; Drug Design; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship	2017
Pharmacokinetics of Continuous Infusion Beta-lactams in the Treatment of Acute Pulmonary Exacerbations in Adult Patients With Cystic Fibrosis. Chest, 2018, Volume: 154, Issue:5 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Retrospective Studies; Symptom Flare Up; Tobramycin	2018
In vitro activity of β-lactams in combination with avibactam against multidrug-resistant Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Achromobacter xylosoxidans isolates from patients with cystic fibrosis. Journal of medical microbiology, 2018, Volume: 67, Issue:9 Topics: Achromobacter denitrificans; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactams; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Stenotrophomonas maltophilia	2018
In vitro activity of seven β-lactams including ceftolozane/tazobactam and ceftazidime/avibactam against Burkholderia cepacia complex, Burkholderia gladioli and other non-fermentative Gram-negative bacilli isolated from cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 2019, 02-01, Volume: 74, Issue:2 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactams; Burkholderia cepacia complex; Burkholderia gladioli; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Combinations; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Tazobactam	2019
Reproducibility between two readout methods of a commercial broth microdilution assay for Pseudomonas aeruginosa isolates from patients with Cystic Fibrosis. Infectious diseases (London, England), 2019, Volume: 51, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactams; Colistin; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reproducibility of Results	2019
Penicillin-binding protein 3 is a common adaptive target among Pseudomonas aeruginosa isolates from adult cystic fibrosis patients treated with β-lactams. International journal of antimicrobial agents, 2019, Volume: 53, Issue:5 Topics: Adaptation, Biological; Adult; Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Cystic Fibrosis; Female; Humans; Longitudinal Studies; Male; Microbial Sensitivity Tests; Mutation, Missense; Penicillin-Binding Proteins; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA; Sputum	2019
Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis. Scientific reports, 2019, 02-22, Volume: 9, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Child; Cystic Fibrosis; DNA, Bacterial; Genetic Variation; Humans; Microbiota; Respiratory System; RNA, Ribosomal, 16S	2019
Challenges and safety of beta-lactam desensitization during extracorporeal membrane oxygenation. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2019, Volume: 122, Issue:6 Topics: Acetates; Allergens; Anaphylaxis; Anti-Infective Agents; Antibiotic Prophylaxis; beta-Lactams; Cetirizine; Cyclopropanes; Cystic Fibrosis; Desensitization, Immunologic; Drug Hypersensitivity; Extracorporeal Membrane Oxygenation; Famotidine; Female; Humans; Immune Tolerance; Male; Quinolines; Respiratory Insufficiency; Sulfides	2019
Pseudomonas aeruginosa populations in the cystic fibrosis lung lose susceptibility to newly applied β-lactams within 3 days. The Journal of antimicrobial chemotherapy, 2019, 10-01, Volume: 74, Issue:10 Topics: Adult; Anti-Bacterial Agents; Bacterial Load; beta-Lactam Resistance; beta-Lactams; Cluster Analysis; Cohort Studies; Cystic Fibrosis; DNA, Bacterial; DNA, Ribosomal; Female; Humans; Lung; Male; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Young Adult	2019
Diversity of β-lactam resistance mechanisms in cystic fibrosis isolates of Pseudomonas aeruginosa: a French multicentre study. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:8 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Child; Child, Preschool; Cystic Fibrosis; Female; France; Gene Expression Profiling; Genes, Bacterial; Genetic Variation; Genotype; Hospitals, University; Humans; Infant; Isoelectric Focusing; Male; Microbial Sensitivity Tests; Middle Aged; Minisatellite Repeats; Molecular Typing; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Young Adult	2013
β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis. Chemical research in toxicology, 2013, Jun-17, Volume: 26, Issue:6 Topics: Aztreonam; beta-Lactamase Inhibitors; beta-Lactams; Cystic Fibrosis; Drug Hypersensitivity; Haptens; Humans; Hypersensitivity; Meropenem; Molecular Structure; Piperacillin; Serum Albumin; T-Lymphocytes; Thienamycins	2013
Beta-lactam hypersensitivity in children with cystic fibrosis: a study in a specialized pediatric center for cystic fibrosis and drug allergy. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2014, Volume: 25, Issue:1 Topics: Adolescent; Adult; beta-Lactams; Child; Cystic Fibrosis; Drug Hypersensitivity; Female; Hospitals, Special; Humans; Immune Tolerance; Male; Pediatrics; Prevalence; Retrospective Studies; Young Adult	2014
Continuous intravenous β-lactam antibiotics in cystic fibrosis patients with severe drug hypersensitivity. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2014, Volume: 113, Issue:2 Topics: Administration, Intravenous; Adolescent; Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Desensitization, Immunologic; Drug Administration Schedule; Drug Hypersensitivity; Female; Humans; Male; Young Adult	2014
Microbiological activity of ceftolozane/tazobactam, ceftazidime, meropenem, and piperacillin/tazobactam against Pseudomonas aeruginosa isolated from children with cystic fibrosis. Diagnostic microbiology and infectious disease, 2015, Volume: 83, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Cystic Fibrosis; Female; Humans; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2015
Follow-up survey of the utilization of anti-pseudomonal beta-lactam antibiotics at U.S. cystic fibrosis centers. Pediatric pulmonology, 2016, Volume: 51, Issue:7 Topics: Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Follow-Up Studies; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Surveys and Questionnaires	2016
Production of extended-spectrum β-lactamases and the potential indirect pathogenic role of Prevotella isolates from the cystic fibrosis respiratory microbiota. International journal of antimicrobial agents, 2016, Volume: 47, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Ceftazidime; Child; Cystic Fibrosis; Female; Humans; Male; Microbial Sensitivity Tests; Microbial Viability; Middle Aged; Prevotella; Pseudomonas aeruginosa; Respiratory Tract Infections; Sequence Analysis, DNA; Young Adult	2016
Optimizing beta-lactam pharmacodynamics against Pseudomonas aeruginosa in adult cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:5 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Drug Administration Routes; Female; Humans; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Models, Theoretical; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections	2016
Multidrug-Resistant Pseudomonas aeruginosa Infection in a Child with Cystic Fibrosis. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Cystic Fibrosis; Drug Hypersensitivity; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2016
Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Cystic Fibrosis; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum	2009
Impact of macrolide therapy on mortality in severe sepsis caused by pneumonia. The European respiratory journal, 2009, Volume: 34, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Bronchiolitis; Community-Acquired Infections; Critical Care; Cystic Fibrosis; Humans; Inflammation; Macrolides; Pneumonia; Randomized Controlled Trials as Topic; Sepsis; Treatment Outcome	2009
Importance of controlling drug-resistant Pseudomonas aeruginosa infection: experience from lung transplantation in a cystic fibrosis case. Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:21 Topics: Aminoglycosides; beta-Lactam Resistance; beta-Lactams; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Lung Transplantation; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Young Adult	2010
A survey of the utilization of anti-pseudomonal beta-lactam therapy in cystic fibrosis patients. Pediatric pulmonology, 2011, Volume: 46, Issue:10 Topics: Anti-Bacterial Agents; beta-Lactams; Cross-Sectional Studies; Cystic Fibrosis; Data Collection; Disease Progression; Drug Utilization; Humans; Pseudomonas	2011
Improved outcomes of patients with end-stage cystic fibrosis requiring invasive mechanical ventilation for acute respiratory failure. Lung, 2011, Volume: 189, Issue:5 Topics: Acute Disease; Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Female; Humans; Male; Malnutrition; Respiration, Artificial; Respiratory Function Tests; Respiratory Insufficiency; Retrospective Studies; Severity of Illness Index; Tobramycin; Treatment Outcome; Young Adult	2011
When the resistance gets clingy: Pseudomonas aeruginosa harboring metallo-β-lactamase gene shows high ability to produce biofilm. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012, Volume: 31, Issue:5 Topics: beta-Lactam Resistance; beta-Lactams; Biofilms; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum	2012
Characterization of the antigen specificity of T-cell clones from piperacillin-hypersensitive patients with cystic fibrosis. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:3 Topics: Adolescent; Adult; Anti-Bacterial Agents; Antigen-Presenting Cells; beta-Lactams; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemokine CCL4; Clone Cells; Cystic Fibrosis; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Humans; Interleukins; Lymphocyte Activation; Male; Mass Spectrometry; Piperacillin; Receptors, Antigen, T-Cell; Young Adult	2012
Intermittent and extended-infusion beta-lactam utilization in cystic fibrosis. Pediatric pulmonology, 2013, Volume: 48, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Humans	2013
Sub-lethal concentrations of antibiotics increase mutation frequency in the cystic fibrosis pathogen Pseudomonas aeruginosa. Letters in applied microbiology, 2013, Volume: 56, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation Rate; Pseudomonas aeruginosa	2013
Efficacy of β-lactams as single agents for treating severe pulmonary exacerbations during pregnancy in cystic fibrosis. American journal of respiratory and critical care medicine, 2012, Dec-15, Volume: 186, Issue:12 Topics: Administration, Intravenous; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Contraindications; Cystic Fibrosis; Disease Progression; Female; Humans; Pregnancy; Pregnancy Complications, Infectious; Pseudomonas Infections; Treatment Outcome	2012
Use of Pseudomonas biofilm susceptibilities to assign simulated antibiotic regimens for cystic fibrosis airway infection. The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Biofilms; Cystic Fibrosis; Drug Combinations; Fluoroquinolones; Humans; Macrolides; Microbial Sensitivity Tests; Pseudomonas	2005
Beta-lactam allergy in adults with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2007, Volume: 6, Issue:4 Topics: Adolescent; Adult; beta-Lactams; Cystic Fibrosis; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Prevalence; Queensland; Retrospective Studies; Risk Factors	2007
Novel approach to the eradication of Pseudomonas aeruginosa in an infant with CF after outpatient treatment failure. Pediatric pulmonology, 2008, Volume: 43, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Area Under Curve; beta-Lactams; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Infusions, Intravenous; Inpatients; Outpatients; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Failure; Treatment Outcome	2008
Activities of new beta-lactam antibiotics against isolates of Pseudomonas aeruginosa from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Carbenicillin; Cefoperazone; Cefotaxime; Ceftazidime; Cephalosporins; Cystic Fibrosis; Imipenem; Penicillins; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections	1981
beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment. Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:5 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carrier Proteins; Cystic Fibrosis; Female; Hexosyltransferases; Humans; Muramoylpentapeptide Carboxypeptidase; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Piperacillin; Pseudomonas aeruginosa; Sputum; Tobramycin	1981
Activities of various beta-lactams and aminoglycosides, alone and in combination, against isolates of Pseudomonas aeruginosa from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:6 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1982
Effect of pH and CO2 on in vitro susceptibility of Pseudomonas cepacia to beta-lactams. Pediatric research, 1994, Volume: 35, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactamase Inhibitors; beta-Lactams; Burkholderia cepacia; Carbon Dioxide; Child; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Microbial Sensitivity Tests; Opportunistic Infections; Pseudomonas Infections; Sputum	1994
Antibodies against Pseudomonas aeruginosa chromosomal beta-lactamase inpatients with cystic fibrosis are markers of the development of resistance of P. aeruginosa to beta-lactams. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:2 Topics: Adolescent; Adult; Antibodies, Bacterial; beta-Lactamases; beta-Lactams; Biomarkers; Child; Child, Preschool; Chromosomes, Bacterial; Cross-Sectional Studies; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Infant; Longitudinal Studies; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Reproducibility of Results; Sensitivity and Specificity	1995
Allergic reactions to parenteral beta-lactam antibiotics in patients with cystic fibrosis. Chest, 1994, Volume: 106, Issue:4 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Drug Hypersensitivity; Female; Fever; Humans; Incidence; Male; Pseudomonas Infections; Retrospective Studies; Time Factors	1994
Spread of beta-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis clinic. Lancet (London, England), 1996, Sep-07, Volume: 348, Issue:9028 Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Cross Infection; Cystic Fibrosis; DNA Fingerprinting; Drug Resistance, Microbial; Genotype; Humans; Infant; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Sputum	1996
Quantitative analysis of the IgG and IgG subclass immune responses to chromosomal Pseudomonas aeruginosa beta-lactamase in serum from patients with cystic fibrosis by western blotting and laser scanning densitometry. Thorax, 1996, Volume: 51, Issue:7 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Blotting, Western; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Densitometry; Drug Resistance, Microbial; Humans; Immunoglobulin G; Infant; Longitudinal Studies; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests	1996
Spread of beta-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis unit. Lancet (London, England), 1996, Dec-07, Volume: 348, Issue:9041 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Cross Infection; Cystic Fibrosis; England; Humans; Outpatient Clinics, Hospital; Pseudomonas aeruginosa; Pseudomonas Infections	1996
Correlation between genotype and beta-lactamases of clinical and environmental strains of Stenotrophomonas maltophilia. The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cystic Fibrosis; Electrophoresis, Gel, Pulsed-Field; Gram-Negative Bacterial Infections; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Sputum; Xanthomonas	1999
High-level beta-lactamase activity in sputum samples from cystic fibrosis patients during antipseudomonal treatment. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Child; Cystic Fibrosis; Female; Humans; Isoelectric Focusing; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum	1992
Protection of Pseudomonas aeruginosa against ciprofloxacin and beta-lactams by homologous alginate. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11 Topics: Alginates; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Polysaccharides; Pseudomonas aeruginosa	1991
The diffusion of beta-lactam antibiotics through mixed gels of cystic fibrosis-derived mucin and Pseudomonas aeruginosa alginate. The Journal of antimicrobial chemotherapy, 1991, Volume: 27, Issue:3 Topics: Alginates; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Diffusion; Humans; Molecular Weight; Mucins; Pseudomonas aeruginosa; Time Factors	1991
[In vitro effect of various antibiotics: beta lactams, aminoglycosides and fluoroquinolones alone and in combination against P. aeruginosa isolated from patients with mucoviscidosis]. Pathologie-biologie, 1989, Volume: 37, Issue:5 Pt 2 Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Ofloxacin; Pseudomonas aeruginosa	1989
Outer membrane permeability in Pseudomonas cepacia: diminished porin content in a beta-lactam-resistant mutant and in resistant cystic fibrosis isolates. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:11 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactamases; beta-Lactams; Cell Membrane Permeability; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Isoelectric Focusing; Lipopolysaccharides; Porins; Pseudomonas	1988
Acute desensitization of a patient with cystic fibrosis allergic to both beta-lactam and aminoglycoside antibiotics. The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:3 Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Skin Tests; Tobramycin	1987
The emergence of resistance to beta-lactam antibiotics during treatment of Pseudomonas aeruginosa lower respiratory tract infections: is combination therapy the solution? Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Pseudomonas Infections; Respiratory Tract Infections	1985
Current needs for new beta-lactam antibiotics in pediatrics. The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B Topics: Abdomen; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Child, Preschool; Cystic Fibrosis; Fever; Humans; Infant; Infant, Newborn; Kinetics; Meningitis; Neutropenia	1985