Page last updated: 2024-08-25

beta-hydroxyisovaleric acid and Cachexia

beta-hydroxyisovaleric acid has been researched along with Cachexia in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Higaki, Y; Kunitake, N; Kuroki, K; Masuda, M; Rikimaru, F; Toh, S1
Holeček, M1
Jo, E; Khamoui, AV; Kim, JS; Lee, WJ; Park, BS1
Bonatto, SJ; Brito, GA; Fernandes, LC; Kryczyk, M; Kuczera, D; Mund, RC; Nunes, EA; Tanhoffer, RA; Yamazaki, RK1
Aversa, Z; Baccino, FM; Bonetto, A; Costelli, P; Lucia, S; Minero, VG; Muscaritoli, M; Penna, F; Rossi Fanelli, F1
Lemmey, A; Maddison, P; Marcora, S1
Baxter, JH; Eley, HL; Mukerji, P; Russell, ST; Tisdale, MJ1
Berk, L; Hug, E; James, J; Kachnic, L; Mahadevan, A; Samuels, M; Schwartz, A1
Abumrad, NN; Barber, A; D'Olimpio, JT; Hourihane, A; May, PE1

Reviews

2 review(s) available for beta-hydroxyisovaleric acid and Cachexia

ArticleYear
Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions.
    Journal of cachexia, sarcopenia and muscle, 2017, Volume: 8, Issue:4

    Topics: Animals; Cachexia; Dietary Supplements; Health; Humans; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Sarcopenia; Valerates; Wasting Syndrome

2017
β-Hydroxy-β-methylbutyrate as a countermeasure for cancer cachexia: a cellular and molecular rationale.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:8

    Topics: Animals; Cachexia; Humans; Muscle, Skeletal; Neoplasms; Proteolysis; Signal Transduction; Valerates

2013

Trials

4 trial(s) available for beta-hydroxyisovaleric acid and Cachexia

ArticleYear
Efficacy of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for the prevention of mucositis induced by platinum-based chemoradiation in head and neck cancer: A phase II study.
    Clinical nutrition ESPEN, 2023, Volume: 57

    Topics: Arginine; Cachexia; Chemoradiotherapy; Glutamine; Head and Neck Neoplasms; Humans; Mucositis; Squamous Cell Carcinoma of Head and Neck

2023
Dietary treatment of rheumatoid cachexia with beta-hydroxy-beta-methylbutyrate, glutamine and arginine: a randomised controlled trial.
    Clinical nutrition (Edinburgh, Scotland), 2005, Volume: 24, Issue:3

    Topics: Arginine; Arthritis, Rheumatoid; Body Composition; Body Mass Index; Cachexia; Dietary Supplements; Double-Blind Method; Female; Glutamine; Hand Strength; Humans; Male; Middle Aged; Surveys and Questionnaires; Valerates

2005
A randomized, double-blind, placebo-controlled trial of a beta-hydroxyl beta-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122).
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2008, Volume: 16, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Arginine; Cachexia; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Placebos; Plethysmography; Quality of Life; Statistics, Nonparametric; Treatment Outcome; Valerates

2008
Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.
    American journal of surgery, 2002, Volume: 183, Issue:4

    Topics: Aged; Arginine; Body Composition; Cachexia; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Muscle, Skeletal; Neoplasms; Treatment Outcome; Valerates

2002

Other Studies

3 other study(ies) available for beta-hydroxyisovaleric acid and Cachexia

ArticleYear
Beta-hydroxy-beta-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-kappaB expression.
    Nutrition research (New York, N.Y.), 2008, Volume: 28, Issue:7

    Topics: Animals; Cachexia; Carcinoma 256, Walker; Cell Division; Glycogen; Liver; Male; Muscle, Skeletal; NF-kappa B; Rats; Rats, Wistar; Valerates

2008
β-hydroxy-β-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia.
    International journal of oncology, 2011, Volume: 38, Issue:3

    Topics: Animals; Body Weight; Cachexia; Down-Regulation; Drug Evaluation, Preclinical; Male; Muscle, Skeletal; Muscular Atrophy; Neoplasms; Neoplasms, Experimental; Random Allocation; Rats; Rats, Wistar; Valerates; Weight Loss

2011
Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli.
    American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cachexia; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Eukaryotic Initiation Factors; Male; Mice; Mice, Inbred Strains; Muscle Fibers, Skeletal; Muscle Neoplasms; Muscle, Skeletal; Neoplasm Transplantation; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Kinases; Proteoglycans; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Valerates

2007