beta-escin has been researched along with Venous-Thrombosis* in 2 studies
2 trial(s) available for beta-escin and Venous-Thrombosis
Article | Year |
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Treatment of superficial vein thrombosis with standardized application of Essaven gel--a placebo-controlled, randomized study.
The aim of this randomized, placebo-controlled study was to evaluate the effect of local treatment with Essaven gel (EG) in comparison with placebo in 30 patients with superficial vein thrombosis (SVT). The 4-week study evaluated the average skin temperature and an analogue symptomatic score. Below-knee SVT was associated with large varicose veins. In patients treated with active EG the decrease in score and in the average, composite skin temperature was significantly larger than in the placebo and control groups. No intolerance was observed. The decrease in score and temperature in the placebo group was mainly due to skin manipulation and massage. In conclusion, treatment with EG in SVT improves symptoms and decreases skin temperature faster. This study confirms earlier observations on the effective use of EG in SVT. Topics: Administration, Topical; Drug Combinations; Escin; Female; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Phospholipids; Skin Temperature; Venous Thrombosis | 2001 |
Treatment of superficial vein thrombosis: clinical evaluation of Essaven gel--a placebo-controlled, 8-week, randomized study.
The aim of this randomized, placebo-controlled study was to evaluate the effect of local treatment with Essaven gel (EG), in comparison with placebo in 30 patients with superficial vein thrombosis (SVT). The 8-week study evaluated SVT with an analogue clinical/symptomatic score. SVT was associated with varicose veins. In patients treated with active EG the decrease in score was significantly larger (p< 0.02) than in the placebo group. No intolerance was observed. The decrease in score in the placebo group was due to spontaneous resolution and to skin manipulation and massage. In conclusion local treatment with EG in SVT improves signs/symptoms much faster than placebo. This study confirms earlier observation on the effective, local use of EG in SVT. Topics: Drug Combinations; Escin; Female; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Phospholipids; Varicose Veins; Venous Thrombosis | 2001 |