beta-endorphin and Neurotic-Disorders

The object of this study was to discover mental functions, humoral regulation and large intestinal motor dysfunction in patients with the irritable bowels syndrome (IBS) in order to develop principles of their differential correction. A group of 106 patients (26 men and 80 women) with the irritable bowels syndrome was examined. The IBS diagnosis was made in accordance with the Rome criteria (1999). The control group included 21 somatically healthy volunteers (16 women and 5 men). Patients from both of the groups underwent clinical and psychological as well as plasma beta-endorphin concentration studies; colonic motor activity was also studied in patients with the IBS by the method of electric colonoscopy. Mental changes and certain particular features of the large intestine humoral regulation and motor activity determining the differential treatment for this category of patients were discovered.

Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Antibody Formation; beta-Endorphin; Female; Gastrointestinal Motility; Humans; Intestine, Large; Irritable Bowel Syndrome; Male; Middle Aged; Neurotic Disorders

Objective. To study the relationship between personality type and variation of plasma peptides in pilots with neurosis. Method. A case-control study was used. 124 male pilots were evaluated with Eysenck's personality checklist, and then level of certain plasma peptides, such as vasoactive intestinal peptide (VIP), beta-endorphin (beta-EP) and angiotensin-II (A-II) were determined. Result. There were significant difference in personality characteristics and personality types between pilots with neuroses and the control. The contents of VIP and beta-EP in plasma showed visible difference between disease group and control. Content of beta-EP in those with inner-unstable type personality was lowest among all the various types. Conclusion. Personality characteristics were different between pilots with neurosis and controls. Levels of VIP and beta-EP in disease group were lower than those in the control. Different personality types had different levels of beta-EP in pilots with neurosis.

Topics: Adult; Aerospace Medicine; Angiotensins; Aviation; beta-Endorphin; Humans; Male; Neurotic Disorders; Personality; Vasoactive Intestinal Peptide

Topics: Animals; beta-Endorphin; Cats; Conditioning, Classical; Higher Nervous Activity; Immunization; Neurotic Disorders; Serum Albumin, Bovine

The relationship among therapeutically induced affective arousal, depressive symptoms, pain and beta-endorphin levels were explored on 6 patients with chronic, active rheumatoid arthritis. An ABA, n of 1 study methodology was utilized, replicated 5 times. This procedure allowed the analysis of individualized changes across time in response to the therapeutic regimen. The results indicated that the treatment regimen activated the beta-endorphin system, particularly during the early and late phases of treatment. However, beta-endorphin response had little effect on reports of subjective pain. Depressive symptoms were affected positively by the treatment but were not strongly correlated to the beta-endorphin response. The results suggest that pain and depression represent independent systems and that beta-endorphin levels serve more as stress markers than analgesics in chronic, organic pain.

Topics: Adult; Aged; Arthritis, Rheumatoid; beta-Endorphin; Defense Mechanisms; Depression; Endorphins; Female; Gestalt Therapy; Humans; Middle Aged; Neurotic Disorders; Pain; Pain Management; Psychotherapy

Topics: Animals; beta-Endorphin; Conditioning, Classical; Macaca mulatta; Motor Activity; Neural Inhibition; Neurotic Disorders; Serum Albumin, Bovine

Topics: Aldosterone; Angiotensin II; beta-Endorphin; Diagnosis, Differential; Ego; Endorphins; Female; Gender Identity; Gonadal Steroid Hormones; Humans; Neurotic Disorders; Oedipus Complex; Premenstrual Syndrome; Prolactin; Social Adjustment; Social Environment