beta-endorphin and Brain-Neoplasms

beta-endorphin has been researched along with Brain-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for beta-endorphin and Brain-Neoplasms

Article	Year
Pituitary pro-opiomelanocortin-cell carcinoma occurring in conjunction with a glioblastoma in a patient with Cushing's disease and subsequent Nelson's syndrome. Clinical endocrinology, 1986, Volume: 25, Issue:2 Pituitary carcinoma is defined as a malignant pituitary tumour associated with blood- or lymph-borne metastases. Cushing's disease is frequently present in patients with this condition. After adrenalectomy for Cushing's disease, a 37-year-old man developed Nelson's syndrome resulting from a pituitary carcinoma with metastases to the spinal cord, cauda equina, heart, liver, and pancreas. The primary tumour and its metastases showed immunocytochemical staining for ACTH, beta-lipotrophin, and variably for beta-endorphin and alpha-melanocyte stimulating hormone (alpha-MSH). A coincidental glioblastoma was also present. Nine cases of Cushing's disease associated with pituitary carcinoma, including the present patient, are documented in the literature. The case reported is only the second in which immunohistochemical staining of the primary pituitary tumour and its metastases was performed, and the first in which ACTH-related peptides, in addition to ACTH itself, were demonstrated in the carcinoma cells. Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Brain Neoplasms; Cushing Syndrome; Endorphins; Glioma; Humans; Male; Melanocyte-Stimulating Hormones; Nelson Syndrome; Neoplasms, Multiple Primary; Pituitary Neoplasms; Pro-Opiomelanocortin	1986
Beta-endorphin concentrations in pituitary and brain areas of animals bearing pituitary hormone secreting tumors. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1983, Volume: 15, Issue:6 Beta-endorphin-like immunoreactivity was measured in the pituitary and brain areas of rats and mice bearing tumors which secrete different pituitary hormones. The DCCXLIIId tumor secretes both luteinizing hormone and follicle stimulating hormone, and the AtT20 tumor secretes corticotropin, beta-lipotropin and beta-endorphin. Beta-endorphin concentrations in the pituitary and brain areas of rats or mice bearing these tumors are similar to those present in the respective controls, but for a decrease in the hindbrain of AtT20 tumor bearing mice. We conclude that peripheral concentrations of gonadotropins, corticotropins, beta-lipotropin and beta-endorphin do not affect the pituitary and brain concentrations of beta-endorphin. Topics: Animals; beta-Endorphin; beta-Lipotropin; Brain Neoplasms; Endorphins; Follicle Stimulating Hormone; Luteinizing Hormone; Mice; Pituitary Hormones; Pituitary Neoplasms; Rats	1983

Article

Year

Pituitary pro-opiomelanocortin-cell carcinoma occurring in conjunction with a glioblastoma in a patient with Cushing's disease and subsequent Nelson's syndrome.

Clinical endocrinology, 1986, Volume: 25, Issue:2

Pituitary carcinoma is defined as a malignant pituitary tumour associated with blood- or lymph-borne metastases. Cushing's disease is frequently present in patients with this condition. After adrenalectomy for Cushing's disease, a 37-year-old man developed Nelson's syndrome resulting from a pituitary carcinoma with metastases to the spinal cord, cauda equina, heart, liver, and pancreas. The primary tumour and its metastases showed immunocytochemical staining for ACTH, beta-lipotrophin, and variably for beta-endorphin and alpha-melanocyte stimulating hormone (alpha-MSH). A coincidental glioblastoma was also present. Nine cases of Cushing's disease associated with pituitary carcinoma, including the present patient, are documented in the literature. The case reported is only the second in which immunohistochemical staining of the primary pituitary tumour and its metastases was performed, and the first in which ACTH-related peptides, in addition to ACTH itself, were demonstrated in the carcinoma cells.

Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; beta-Endorphin; beta-Lipotropin; Brain Neoplasms; Cushing Syndrome; Endorphins; Glioma; Humans; Male; Melanocyte-Stimulating Hormones; Nelson Syndrome; Neoplasms, Multiple Primary; Pituitary Neoplasms; Pro-Opiomelanocortin

1986

Beta-endorphin concentrations in pituitary and brain areas of animals bearing pituitary hormone secreting tumors.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1983, Volume: 15, Issue:6

Beta-endorphin-like immunoreactivity was measured in the pituitary and brain areas of rats and mice bearing tumors which secrete different pituitary hormones. The DCCXLIIId tumor secretes both luteinizing hormone and follicle stimulating hormone, and the AtT20 tumor secretes corticotropin, beta-lipotropin and beta-endorphin. Beta-endorphin concentrations in the pituitary and brain areas of rats or mice bearing these tumors are similar to those present in the respective controls, but for a decrease in the hindbrain of AtT20 tumor bearing mice. We conclude that peripheral concentrations of gonadotropins, corticotropins, beta-lipotropin and beta-endorphin do not affect the pituitary and brain concentrations of beta-endorphin.

Topics: Animals; beta-Endorphin; beta-Lipotropin; Brain Neoplasms; Endorphins; Follicle Stimulating Hormone; Luteinizing Hormone; Mice; Pituitary Hormones; Pituitary Neoplasms; Rats

1983