beta-endorphin and Atrophy

beta-endorphin has been researched along with Atrophy* in 1 studies

Other Studies

1 other study(ies) available for beta-endorphin and Atrophy

ArticleYear
Beta-endorphin, beta-lipotropin and adrenocorticotropic hormone levels in cerebrospinal fluid, and brain damage in chronic alcoholics.
    European neurology, 1983, Volume: 22, Issue:4

    In 34 chronic alcoholics, subdivided into two groups according to the state of the blood-brain barrier (BBB), beta-lipotropin (beta-LPH), beta-endorphin (beta-EP), ACTH and cortisol levels were determined in basal conditions in the plasma and cerebrospinal fluid (CSF). Hormonal concentrations were correlated with brain damage and mnesic function. The results indicate the reduced CSF beta-EP content in chronic alcoholics and suggest that peripheral beta-EP may penetrate into the CSF compartment when there is BBB damage. They also sustain the different origins of central and peripheral pro-opiocortin-related peptides, and support the concept that beta-EP, beta-LPH and ACTH may be autonomously regulated at the central level. Moreover, both morphological brain damage and mnesic impairment in chronic alcoholics are unrelated to CSF peptide levels. The role of opioid peptides in the nature of alcohol-seeking behavior is supported.

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Alcoholism; Atrophy; beta-Endorphin; beta-Lipotropin; Brain; Brain Damage, Chronic; Endorphins; Humans; Male; Middle Aged; Tomography, X-Ray Computed

1983