Page last updated: 2024-10-16

beta-alanine and Thrombopenia

beta-alanine has been researched along with Thrombopenia in 6 studies

Research Excerpts

ExcerptRelevanceReference
"To present a case of dabigatran use for nonvalvular atrial fibrillation in a patient from a population for whom it has not been studied."7.78Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies. ( Fieland, D; Taylor, M, 2012)
"To present a case of dabigatran use for nonvalvular atrial fibrillation in a patient from a population for whom it has not been studied."3.78Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies. ( Fieland, D; Taylor, M, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takami, H1
Oshiro, N1
Hiraoka, F1
Murao, M1
Ide, T1
Krauel, K1
Hackbarth, C1
Fürll, B1
Greinacher, A1
Fieland, D1
Taylor, M1
Bilen, O1
Teruya, J1
Bednar, B1
Cook, JJ1
Holahan, MA1
Cunningham, ME1
Jumes, PA1
Bednar, RA1
Hartman, GD1
Gould, RJ1
Vermes, A1
Guchelaar, HJ1
van Kuilenburg, AB1
Dankert, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2 O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Patients Receiving Induction or Consolidation Therapy for Acute Myeloid Leukemia[NCT02056782]Phase 112 participants (Actual)Interventional2013-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Subjects Who Achieved a Morphologic Complete Remission

"A secondary endpoint of this study was to determine whether there was preliminary evidence of an effect of dociparstat on remission rate following cytarabine and idarubicin induction in acute myeloid leukemia (AML) patients, which included complete remission (CR) rate (with neutrophil and platelet count recovery) after the first induction cycle.~Morphologic CR was defined as absolute neutrophil count (ANC) >1000/μL, platelet count >100,000/μL, <5% bone marrow blasts, no Auer rods, and no evidence of extramedullary disease." (NCT02056782)
Timeframe: Day 1 to Day 35 (35 days)

InterventionParticipants (Count of Participants)
Dociparstat11

Time (Days) to Transfusion-independent Platelet Recovery (Platelet Counts Values ≥ 20,000/μL and ≥ 50,000/μL Without a Platelet Transfusion)

A primary endpoint of this study was evidence of an effect of dociparstat on transfusion independent platelet recovery time. The time (days) to transfusion-independent platelet recovery will be defined as the number of days from the first day of chemotherapy until the first of 5 consecutive days with platelet counts values ≥ 20,000/μL and ≥ 50,000/μL without a platelet transfusion. (NCT02056782)
Timeframe: Day 1 to Day 35 (35 days)

Interventiondays (Mean)
Platelet count of ≥20,000/µLPlatelet count of ≥50,000/µL
Dociparstat21.323.1

Reviews

1 review available for beta-alanine and Thrombopenia

ArticleYear
Complications of anticoagulation.
    Disease-a-month : DM, 2012, Volume: 58, Issue:8

    Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Dabigatran; Drug Contamination;

2012

Trials

1 trial available for beta-alanine and Thrombopenia

ArticleYear
5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:1

    Topics: Adult; Aged; beta-Alanine; Biotransformation; Bone Marrow; Candidiasis; Female; Flucytosine; Fluorou

2002

Other Studies

4 other studies available for beta-alanine and Thrombopenia

ArticleYear
Rapid resolution of a spontaneous large chronic subdural haematoma in the posterior fossa under conservative treatment with platelet administration to aplastic anaemia.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Aged, 80 and over; Anemia, Aplastic; Anticoagulants; Benzimidazoles; beta-Alanine; Cranial Fossa, Po

2013
Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies.
    Blood, 2012, Feb-02, Volume: 119, Issue:5

    Topics: Antibodies; Anticoagulants; Benzimidazoles; beta-Alanine; Blood Cells; Cells, Cultured; Dabigatran;

2012
Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:1

    Topics: Aged; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Coronary Artery Bypass; Dabi

2012
Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa.
    Blood, 1999, Jul-15, Volume: 94, Issue:2

    Topics: Animals; Autoantibodies; Autoimmune Diseases; Azepines; beta-Alanine; Blood Platelets; Disease Susce

1999