Page last updated: 2024-10-16

beta-alanine and Kidney Diseases

beta-alanine has been researched along with Kidney Diseases in 15 studies

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"The comparative safety of dabigatran versus warfarin for treatment of nonvalvular atrial fibrillation in general practice settings has not been established."7.81Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation. ( Goulding, MR; Graham, DJ; Houstoun, M; Kelman, JA; Levenson, M; MaCurdy, TE; Mott, K; Reichman, ME; Sheu, TC; Southworth, MR; Wernecke, M; Worrall, C; Zhang, R, 2015)
"A 65-year-old man, who had been treated with dabigatran for 66 days prior to electrical cardioversion, developed extensive intestinal, renal and cerebral thromboembolism five days after cardioversion."7.79[Extensive thromboembolism after cardioversion in a patient treated with dabigatran]. ( Buch, TN; Holm, J; Munck, LK, 2013)
"Dabigatran, administered orally as the prodrug dabigatran etexilate (DE), is a direct thrombin inhibitor shown to be effective in the prevention of stroke and systemic embolism in patients with atrial fibrillation (AF)."7.78Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation. ( Clemens, A; Friedman, J; Haertter, S; Lehr, T; Liesenfeld, KH; Reilly, PA; Staab, A, 2012)
"The comparative safety of dabigatran versus warfarin for treatment of nonvalvular atrial fibrillation in general practice settings has not been established."3.81Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation. ( Goulding, MR; Graham, DJ; Houstoun, M; Kelman, JA; Levenson, M; MaCurdy, TE; Mott, K; Reichman, ME; Sheu, TC; Southworth, MR; Wernecke, M; Worrall, C; Zhang, R, 2015)
"A 65-year-old man, who had been treated with dabigatran for 66 days prior to electrical cardioversion, developed extensive intestinal, renal and cerebral thromboembolism five days after cardioversion."3.79[Extensive thromboembolism after cardioversion in a patient treated with dabigatran]. ( Buch, TN; Holm, J; Munck, LK, 2013)
"Dabigatran, administered orally as the prodrug dabigatran etexilate (DE), is a direct thrombin inhibitor shown to be effective in the prevention of stroke and systemic embolism in patients with atrial fibrillation (AF)."3.78Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation. ( Clemens, A; Friedman, J; Haertter, S; Lehr, T; Liesenfeld, KH; Reilly, PA; Staab, A, 2012)
"The objective of this work was to derive a dosing regimen for dabigatran in patients with severe renal impairment by modeling and simulation."2.77Clinical pharmacology basis of deriving dosing recommendations for dabigatran in patients with severe renal impairment. ( Hariharan, S; Madabushi, R, 2012)
" In contrast to warfarin, most NOACs need dosage adjustments in renal impairment and are contraindicated in severe liver impairment, and there are no specific antidotes for treating NOAC-related over-anticoagulation."2.50New oral anticoagulants in practice: pharmacological and practical considerations. ( Bajorek, B; Wang, Y, 2014)
"Dabigatran is an oral direct thrombin inhibitor widely used to prevent and treat various thromboembolic complications."2.49Dabigatran and kidney disease: a bad combination. ( Berns, JS; Chaknos, CM; Knauf, F; Perazella, MA, 2013)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (73.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Liu, L1
Liu, F1
Guan, Y1
Zou, J1
Zhang, C1
Xiong, C1
Zhao, TC1
Bayliss, G1
Li, X1
Zhuang, S1
Buch, TN1
Holm, J1
Munck, LK1
Knauf, F1
Chaknos, CM1
Berns, JS1
Perazella, MA1
Wang, Y1
Bajorek, B1
Tran, H1
Joseph, J1
Young, L1
McRae, S1
Curnow, J1
Nandurkar, H1
Wood, P1
McLintock, C1
Graham, DJ1
Reichman, ME1
Wernecke, M1
Zhang, R1
Southworth, MR1
Levenson, M1
Sheu, TC1
Mott, K1
Goulding, MR1
Houstoun, M1
MaCurdy, TE1
Worrall, C1
Kelman, JA1
Lane, DA1
Wood, K1
Kooiman, J1
van de Peppel, WR1
van der Meer, FJ1
Huisman, MV1
Lehr, T1
Haertter, S1
Liesenfeld, KH1
Staab, A1
Clemens, A1
Reilly, PA1
Friedman, J1
Hariharan, S1
Madabushi, R1
Lillo-Le Louët, A1
Wolf, M1
Soufir, L1
Galbois, A1
Dumenil, AS1
Offenstadt, G1
Samama, MM1
de Gea-García, JH1
Alvarez, M1
Ruiz-Villa, G1
Jiménez-Parra, JD1
Klingensmith, WC2
Fritzberg, AR2
Spitzer, VM2
Johnson, DL1
Kuni, CC2
Williamson, MR1
Washer, G1
Weil, R1
Soini, I1
Vorne, M1
Karhunen, M1
Latteier, JL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Monitor System for the Safety of Dabigatran Anticoagulation Treatment in Nonvalvular Atrial Fibrillation[NCT02414035]1,496 participants (Actual)Observational2015-03-22Completed
Randomized Evaluation of Decision Support Interventions for Atrial Fibrillation[NCT04357288]1,200 participants (Anticipated)Interventional2020-12-16Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for beta-alanine and Kidney Diseases

ArticleYear
Dabigatran and kidney disease: a bad combination.
    Clinical journal of the American Society of Nephrology : CJASN, 2013, Volume: 8, Issue:9

    Topics: Antidotes; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation Factors; Blood Coagulation

2013
New oral anticoagulants in practice: pharmacological and practical considerations.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:3

    Topics: Administration, Oral; Aging; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Comp

2014

Trials

1 trial available for beta-alanine and Kidney Diseases

ArticleYear
Clinical pharmacology basis of deriving dosing recommendations for dabigatran in patients with severe renal impairment.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:1 Suppl

    Topics: Adult; Aged; Antithrombins; Benzimidazoles; beta-Alanine; Computer Simulation; Dabigatran; Female; H

2012

Other Studies

12 other studies available for beta-alanine and Kidney Diseases

ArticleYear
Critical roles of SMYD2 lysine methyltransferase in mediating renal fibroblast activation and kidney fibrosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:7

    Topics: Animals; Benzoxazines; beta-Alanine; Cell Proliferation; Epithelial Cells; Epithelial-Mesenchymal Tr

2021
[Extensive thromboembolism after cardioversion in a patient treated with dabigatran].
    Ugeskrift for laeger, 2013, Feb-04, Volume: 175, Issue:6

    Topics: Aged; Antithrombins; Benzimidazoles; beta-Alanine; Cerebral Infarction; Dabigatran; Electric Counter

2013
New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural/bleeding management. Australasian Society of Thrombosis and Haemostasis.
    Internal medicine journal, 2014, Volume: 44, Issue:6

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Coagu

2014
Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation.
    Circulation, 2015, Jan-13, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles

2015
Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation.
    Circulation, 2015, Jan-13, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles

2015
Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation.
    Circulation, 2015, Jan-13, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles

2015
Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation.
    Circulation, 2015, Jan-13, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles

2015
Cardiology patient page. Patient guide for taking the non-vitamin K antagonist oral anticoagulants for atrial fibrillation.
    Circulation, 2015, Apr-21, Volume: 131, Issue:16

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Contraindic

2015
Incidence of chronic kidney disease in patients with atrial fibrillation and its relevance for prescribing new oral antithrombotic drugs.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:8

    Topics: Administration, Oral; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Biomarkers; Chronic Disease

2011
Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:9

    Topics: Antithrombins; Area Under Curve; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Computer Simulat

2012
Life-threatening bleeding in four patients with an unusual excessive response to dabigatran: implications for emergency surgery and resuscitation.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:3

    Topics: Aged; Aged, 80 and over; Antithrombins; Arthroplasty, Replacement; Atrial Fibrillation; Benzimidazol

2012
[Wünderlich syndrome in patient anticoagulated with dabigatran].
    Medicina clinica, 2013, Aug-17, Volume: 141, Issue:4

    Topics: Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Brain Ischemia

2013
Clinical evaluation of Tc-99m N,N'-bis(mercaptoacetyl)-2,3-diaminopropanoate as a replacement for I-131 hippurate: concise communication.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1984, Volume: 25, Issue:1

    Topics: Alanine; beta-Alanine; Computers; Computers, Analog; Hippurates; Humans; Iodine Radioisotopes; Kidne

1984
[New indications of kidney function by gamma imaging].
    Duodecim; laaketieteellinen aikakauskirja, 1989, Volume: 105, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Alanine; beta-Alanine; Female; Humans; Iodohippuric Acid; Kidney Dis

1989
Clinical comparison of technetium-99m-N,N-bis(mercaptoacetyl)-2,3-diaminopropanoate with technetium-99m DTPA for renal imaging.
    Clinical nuclear medicine, 1985, Volume: 10, Issue:11

    Topics: Alanine; beta-Alanine; Humans; Kidney; Kidney Diseases; Organotechnetium Compounds; Pentetic Acid; R

1985