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beta-alanine and Diabetes Mellitus, Adult-Onset

beta-alanine has been researched along with Diabetes Mellitus, Adult-Onset in 19 studies

Research Excerpts

ExcerptRelevanceReference
"Dabigatran is a direct thrombin inhibitor indicated for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation."3.80[Patient with acute renal injury presenting dabigatran overdose: Hemodialysis for surgery]. ( Bachellerie, B; Conil, JM; Crognier, L; Fourcade, O; Georges, B; Ruiz, S; Seguin, T, 2014)
"To conduct a dose-response assessment of the efficacy and safety of the glucagon receptor antagonist PF-06291874 in adults with type 2 diabetes (T2DM) using stable doses of metformin."2.87Efficacy and safety of the glucagon receptor antagonist PF-06291874: A 12-week, randomized, dose-response study in patients with type 2 diabetes mellitus on background metformin therapy. ( Bergman, AJ; Calle, RA; Chidsey, K; Kazierad, DJ; Somayaji, VR, 2018)
" In an acute dog glucagon challenge test, compound 13K significantly inhibited glucagon-mediated blood glucose increase when dosed orally at 10 mg/kg."1.51Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes. ( Demarest, K; DesJarlais, RL; DiLoreto, K; Du, F; Eckardt, A; Gaul, MD; Liang, Y; Rentzeperis, D; Santulli, R; Shook, B; Song, F; Xu, G, 2019)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.53)29.6817
2010's13 (68.42)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Sugimoto, T3
Kamei, Y3
Matthews, JJ3
Turner, MD3
Santos, L3
Elliott-Sale, KJ3
Sale, C3
Xu, G1
Gaul, MD1
Song, F1
Du, F1
Liang, Y1
DesJarlais, RL1
DiLoreto, K1
Shook, B1
Rentzeperis, D1
Santulli, R1
Eckardt, A1
Demarest, K1
Dolan, E2
Swinton, PA2
Artioli, GG2
Sa, Z1
Zhou, J1
Zou, Y1
Su, Z1
Gu, X1
Savolainen, O1
Lind, MV1
Bergström, G1
Fagerberg, B1
Sandberg, AS1
Ross, A1
Kazierad, DJ2
Chidsey, K1
Somayaji, VR1
Bergman, AJ1
Calle, RA1
Li, J1
Qiu, P1
Wang, S1
Wu, J1
He, Q1
Li, K1
Xu, L1
Ribés-Cruz, JJ1
Torregrosa-Maicas, I1
Ramos-Tomás, C1
Solís-Salguero, MA1
Puchades-Montesa, MJ1
González-Rico, MA1
Juan-García, I1
Tomás-Simó, P1
Tejedor-Alonso, S1
Zambrano-Esteves, P1
Miguel-Carrasco, A1
Bachellerie, B1
Ruiz, S1
Conil, JM1
Crognier, L1
Seguin, T1
Georges, B1
Fourcade, O1
Grover, S1
Dhanjal, JK1
Goyal, S1
Grover, A1
Sundar, D1
Guan, HP1
Yang, X2
Lu, K1
Wang, SP1
Castro-Perez, JM1
Previs, S1
Wright, M1
Shah, V1
Herath, K1
Xie, D1
Szeto, D1
Forrest, G1
Xiao, JC1
Palyha, O1
Sun, LP1
Andryuk, PJ1
Engel, SS1
Xiong, Y2
Lin, S1
Kelley, DE1
Erion, MD1
Davis, HR1
Wang, L1
Bergman, A1
Tan, B1
Erion, DM1
Somayaji, V1
Lee, DS1
Rolph, T1
Pelantová, H1
Bugáňová, M1
Holubová, M1
Šedivá, B1
Zemenová, J1
Sýkora, D1
Kaválková, P1
Haluzík, M1
Železná, B1
Maletínská, L1
Kuneš, J1
Kuzma, M1
Guo, J1
Candelore, MR1
Liang, R1
Miller, C1
Dallas-Yang, Q1
Jiang, G1
McCann, PE1
Qureshi, SA1
Tong, X1
Xu, SS1
Shang, J1
Vincent, SH1
Tota, LM1
Wright, MJ1
Zhang, BB1
Tata, JR1
Parmee, ER1
de Gea-García, JH1
Alvarez, M1
Ruiz-Villa, G1
Jiménez-Parra, JD1
Kobayashi, Y1
Yasuba, H1
Yamashita, K1
Kita, H1
Chiba, W1
Hitomi, S1
Lau, J1
Behrens, C1
Sidelmann, UG1
Knudsen, LB1
Lundt, B1
Sams, C1
Ynddal, L1
Brand, CL1
Pridal, L1
Ling, A1
Kiel, D1
Plewe, M1
Shi, S1
Madsen, P1

Reviews

2 reviews available for beta-alanine and Diabetes Mellitus, Adult-Onset

ArticleYear
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Regulation of Skeletal Muscle Function by Amino Acids, Especially Non-Proteinogenic Amino Acids.
    Journal of nutritional science and vitaminology, 2022, Volume: 68, Issue:Supplement

    Topics: Aged; Amino Acids; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Humans; Leucine; Mammals; Mice;

2022
Effect of Carnosine or β-Alanine Supplementation on Markers of Glycemic Control and Insulin Resistance in Humans and Animals: A Systematic Review and Meta-analysis.
    Advances in nutrition (Bethesda, Md.), 2021, 12-01, Volume: 12, Issue:6

    Topics: Animals; Bayes Theorem; beta-Alanine; Blood Glucose; Carnosine; Diabetes Mellitus, Type 2; Dietary S

2021

Trials

2 trials available for beta-alanine and Diabetes Mellitus, Adult-Onset

ArticleYear
Efficacy and safety of the glucagon receptor antagonist PF-06291874: A 12-week, randomized, dose-response study in patients with type 2 diabetes mellitus on background metformin therapy.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:11

    Topics: Adolescent; Adult; Aged; beta-Alanine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dos

2018
Effects of multiple ascending doses of the glucagon receptor antagonist PF-06291874 in patients with type 2 diabetes mellitus.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:8

    Topics: Adult; Aged; Alanine Transaminase; Amino Acids; Aspartate Aminotransferases; beta-Alanine; Blood Glu

2016

Other Studies

15 other studies available for beta-alanine and Diabetes Mellitus, Adult-Onset

ArticleYear
Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells.
    Amino acids, 2023, Volume: 55, Issue:3

    Topics: beta-Alanine; Carnosine; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Resistance; Ma

2023
Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes.
    Bioorganic & medicinal chemistry letters, 2019, 10-15, Volume: 29, Issue:20

    Topics: Amino Acid Sequence; Animals; beta-Alanine; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitu

2019
The effect of carnosine or β-alanine supplementation on markers of glycaemic control and insulin resistance in human and animal studies: a protocol for a systematic review and meta-analysis.
    Systematic reviews, 2020, 12-05, Volume: 9, Issue:1

    Topics: Bayes Theorem; beta-Alanine; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Glycemic Con

2020
Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis.
    Genomics, proteomics & bioinformatics, 2017, Volume: 15, Issue:4

    Topics: Amino Acid Sequence; Animals; beta-Alanine; Binding Sites; Diabetes Mellitus, Type 2; Glucagon-Like

2017
Biomarkers of food intake and nutrient status are associated with glucose tolerance status and development of type 2 diabetes in older Swedish women.
    The American journal of clinical nutrition, 2017, Volume: 106, Issue:5

    Topics: alpha-Tocopherol; beta-Alanine; Biomarkers; Case-Control Studies; Cholesterol; Diabetes Mellitus, Ty

2017
β-N-Oxalyl-L-α,β-diaminopropionic acid from Panax notoginseng plays a major role in the treatment of type 2 diabetic nephropathy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 114

    Topics: Amino Acids, Diamino; Animals; beta-Alanine; Cell Line; Cell Proliferation; Diabetes Mellitus, Exper

2019
Dabigatran-induced upper intestinal bleeding in a patient with chronic kidney disease.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2013, Nov-13, Volume: 33, Issue:6

    Topics: Aged, 80 and over; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Diabetes Mellitus,

2013
[Patient with acute renal injury presenting dabigatran overdose: Hemodialysis for surgery].
    Annales francaises d'anesthesie et de reanimation, 2014, Volume: 33, Issue:1

    Topics: Acute Kidney Injury; Aged, 80 and over; Alzheimer Disease; Antithrombins; Atrial Fibrillation; Benzi

2014
Computational identification of novel natural inhibitors of glucagon receptor for checking type II diabetes mellitus.
    BMC bioinformatics, 2014, Volume: 15 Suppl 16

    Topics: beta-Alanine; Blood Glucose; Computational Biology; Diabetes Mellitus, Type 2; Glucagon; High-Throug

2014
Glucagon receptor antagonism induces increased cholesterol absorption.
    Journal of lipid research, 2015, Volume: 56, Issue:11

    Topics: Animals; beta-Alanine; Cholesterol; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Humans;

2015
Urinary metabolomic profiling in mice with diet-induced obesity and type 2 diabetes mellitus after treatment with metformin, vildagliptin and their combination.
    Molecular and cellular endocrinology, 2016, 08-15, Volume: 431

    Topics: Adamantane; Animals; beta-Alanine; Diabetes Mellitus, Type 2; Diet; Glucose Tolerance Test; Hypoglyc

2016
Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the treatment of type II diabetes.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Area Under Curve; beta-Alanine; Blood Glucose; CHO Cells; Cricetinae; Cricetulus; Diabetes

2012
[Wünderlich syndrome in patient anticoagulated with dabigatran].
    Medicina clinica, 2013, Aug-17, Volume: 141, Issue:4

    Topics: Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Brain Ischemia

2013
[A case of successful medical treatment for necrotizing fasciitis of the chest wall with diabetic nephropathy].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2005, Volume: 43, Issue:3

    Topics: Anti-Bacterial Agents; beta-Alanine; Cilastatin; Cilastatin, Imipenem Drug Combination; Diabetes Mel

2005
New beta-alanine derivatives are orally available glucagon receptor antagonists.
    Journal of medicinal chemistry, 2007, Jan-11, Volume: 50, Issue:1

    Topics: Administration, Oral; Animals; beta-Alanine; Biological Availability; Diabetes Mellitus, Experimenta

2007