Page last updated: 2024-10-16

beta-alanine and Corneal Edema

beta-alanine has been researched along with Corneal Edema in 10 studies

Corneal Edema: An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.

Research Excerpts

ExcerptRelevanceReference
"Twenty-nine subjects with symptomatic Fuchs dystrophy were enrolled and randomized to use netarsudil or placebo eye drops once daily for 3 months."3.01Randomized, Double-Masked, Pilot Study of Netarsudil 0.02% Ophthalmic Solution for Treatment of Corneal Edema in Fuchs Dystrophy. ( Price, FW; Price, MO, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's9 (90.00)2.80

Authors

AuthorsStudies
Lyons, LJ1
Wu, KY1
Baratz, KH1
Sit, AJ1
Wisely, CE1
Liu, KC1
Gupta, D1
Carlson, AN1
Asrani, SG1
Kim, T1
Moumneh, K1
Sheybani, A1
Fellman, RL1
Godfrey, DG1
Grover, DS1
Chen, TC1
Jurkunas, U1
Chodosh, J1
Chen, H1
McMillin, JC1
Frankfort, BJ1
Al-Mohtaseb, Z1
Davies, E1
LoBue, SA1
Moustafa, GA1
Vu, A1
Amin, M1
Nguyen, T1
Goyal, H1
Price, MO1
Price, FW1
Chu, MJ1
Song, M1
Palmares, T1
Song, A1
Song, J1
Fernandez, MM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Primary Rhegmatogenous Detachments and Retinal Detachment Due to Proliferative Vitreoretinopathy or Open-Globe Injury: A Phase I/II Clinical Trial[NCT06033703]Phase 1/Phase 248 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Prospective Randomized Study to Determine Whether Use of Rhopressa™ Can Ameliorate Corneal Edema Associated With Fuchs Dystrophy[NCT04051463]Phase 2/Phase 329 participants (Actual)Interventional2019-08-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Central Corneal Thickness

Central corneal thickness at 1 month after randomization minus central corneal thickness at baseline (NCT04051463)
Timeframe: 1 month

Interventionmicrons (Mean)
Netarsudil-23
Placebo-2

Change in Corrected Distance Visual Acuity (CDVA)

Change in CDVA (lines read on the eye chart at 3 months minus lines read at baseline) (NCT04051463)
Timeframe: 3 months

Interventionlines on the eye chart (Mean)
Netarsudil1.9
Placebo0.3

Reviews

2 reviews available for beta-alanine and Corneal Edema

ArticleYear
Honeycomb Epithelial Edema Associated With Rho Kinase Inhibition: A Case Series and Review of the Literature.
    Cornea, 2022, Feb-01, Volume: 41, Issue:2

    Topics: Benzoates; beta-Alanine; Corneal Edema; Epithelium, Corneal; Humans; Intraocular Pressure; Ocular Hy

2022
Rhopressa-induced corneal edema: a case report.
    Journal of medical case reports, 2021, Apr-02, Volume: 15, Issue:1

    Topics: Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Edema; Female; Humans; Ophthalmic So

2021

Trials

1 trial available for beta-alanine and Corneal Edema

ArticleYear
Randomized, Double-Masked, Pilot Study of Netarsudil 0.02% Ophthalmic Solution for Treatment of Corneal Edema in Fuchs Dystrophy.
    American journal of ophthalmology, 2021, Volume: 227

    Topics: Administration, Ophthalmic; Aged; Benzoates; beta-Alanine; Corneal Edema; Corneal Pachymetry; Double

2021

Other Studies

7 other studies available for beta-alanine and Corneal Edema

ArticleYear
Reticular Bullous Epithelial Edema in Corneas Treated with Netarsudil: A Case Series.
    American journal of ophthalmology, 2020, Volume: 217

    Topics: Aged; Aged, 80 and over; Benzoates; beta-Alanine; Corneal Edema; Epithelium, Corneal; Female; Humans

2020
Reticular Corneal Edema or Corneal Honeycombing in Eyes Treated With Netarsudil: A Case Series.
    Journal of glaucoma, 2020, Volume: 29, Issue:7

    Topics: Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Edema; Female; Glaucoma, Open-Angle;

2020
A Patient With Glaucoma With Corneal Edema.
    JAMA ophthalmology, 2020, 08-01, Volume: 138, Issue:8

    Topics: Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Edema; Epithelium, Corneal; Glaucoma, Open

2020
Reticular Epithelial Edema: An Uncommon Side Effect of ROCK/NET Inhibitor Netarsudil.
    Journal of glaucoma, 2020, Volume: 29, Issue:11

    Topics: Aged; Benzoates; beta-Alanine; Cataract Extraction; Corneal Diseases; Corneal Edema; Descemet Stripp

2020
Case Series: Novel Utilization of Rho-Kinase Inhibitor for the Treatment of Corneal Edema.
    Cornea, 2021, Volume: 40, Issue:1

    Topics: Aged; Aged, 80 and over; Benzoates; beta-Alanine; Corneal Edema; Corneal Endothelial Cell Loss; Corn

2021
Transient Reticular Cystic Corneal Epithelial Edema With Topical Netarsudil: A Case Series and Review.
    Cornea, 2021, 08-01, Volume: 40, Issue:8

    Topics: Aged; Aged, 80 and over; Benzoates; beta-Alanine; Corneal Edema; Epithelium, Corneal; Humans; Intrao

2021
Reticular Epithelial Edema in Edematous Corneas Treated with Netarsudil.
    Ophthalmology, 2018, Volume: 125, Issue:11

    Topics: Benzoates; beta-Alanine; Corneal Edema; Epithelium, Corneal; Humans; rho-Associated Kinases; Tomogra

2018