Page last updated: 2024-10-16

beta-alanine and Cerebral Hemorrhage

beta-alanine has been researched along with Cerebral Hemorrhage in 28 studies

Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"A network meta-analysis of the three new oral anticoagulants was performed from the three trials comparing dabigatran, rivaroxaban and apixaban with warfarin in patients with atrial fibrillation."8.88Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis. ( Diener, HC; Harenberg, J; Lip, GY; Marder, VJ; Marx, S; Wehling, M; Weiss, C, 2012)
"This experimental study of a rat ICH model indicates that dabigatran-related ICH may not increase the risk of delayed hematoma expansion."7.81Does dabigatran increase the risk of delayed hematoma expansion in a rat model of collagenase-induced intracerebral hemorrhage? ( Hirose, Y; Inamasu, J; Tanoue, S; Toyama, H; Yamada, M, 2015)
"Warfarin-related intracerebral hemorrhage carries a particularly high risk of neurologic deterioration and death because of a high rate of hematoma expansion of about 50%."5.40Dabigatran-related intracerebral hemorrhage resulting in hematoma expansion. ( Damgaard, D; Simonsen, CZ; Steiner, T; Tietze, A, 2014)
"Ischemic stroke was induced by transient middle cerebral artery occlusion (tMCAO) for 1 h or 3 h."5.38No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke. ( Bohmann, F; Foerch, C; Lindhoff-Last, E; Mirceska, A; Pfeilschifter, J; Pfeilschifter, W; Steinmetz, H, 2012)
"A network meta-analysis of the three new oral anticoagulants was performed from the three trials comparing dabigatran, rivaroxaban and apixaban with warfarin in patients with atrial fibrillation."4.88Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis. ( Diener, HC; Harenberg, J; Lip, GY; Marder, VJ; Marx, S; Wehling, M; Weiss, C, 2012)
"This experimental study of a rat ICH model indicates that dabigatran-related ICH may not increase the risk of delayed hematoma expansion."3.81Does dabigatran increase the risk of delayed hematoma expansion in a rat model of collagenase-induced intracerebral hemorrhage? ( Hirose, Y; Inamasu, J; Tanoue, S; Toyama, H; Yamada, M, 2015)
"Severe bleeding associated with dabigatran frequently requires intensive care management."3.81Comparison of intermittent and continuous extracorporeal treatments for the enhanced elimination of dabigatran. ( Bernier-Jean, A; Bouchard, J; Eris, JM; Ghannoum, M; Kershaw, G; Patel, JP; Roberts, DM; Tran, H; Weatherburn, C; Williamson, D, 2015)
"Lack of specific antidotes is a major concern in intracerebral hemorrhage (ICH) related to direct anticoagulants including dabigatran (OAC-ICH)."3.81Idarucizumab Improves Outcome in Murine Brain Hemorrhage Related to Dabigatran. ( Mracsko, E; Na, SY; van Ryn, J; Veltkamp, R, 2015)
"Due to lack of an available antidote, activated prothrombin complex concentrate was utilized as a nonspecific procoagulant to stabilize an intracerebral hemorrhage in a patient on dabigatran."3.80Management of dabigatran-associated intracerebral and intraventricular hemorrhage: a case report. ( Faust, AC; Peterson, EJ, 2014)
" We determined intracerebral hemorrhage volume and functional outcome in a standardized TBI model in mice treated with warfarin or dabigatran."3.80Translational insights into traumatic brain injury occurring during dabigatran or warfarin anticoagulation. ( Foerch, C; Lauer, A; Leung, W; Lo, EH; Lok, J; Schaefer, JH; Van Cott, EM; van Leyen, K; van Ryn, J; Whalen, M; Wu, L, 2014)
"Dabigatran etexilate (DE) has recently been introduced for stroke prevention in atrial fibrillation, but management of acute ischaemic stroke during therapy with DE is a challenge."3.79Anticoagulation with dabigatran does not increase secondary intracerebral haemorrhage after thrombolysis in experimental cerebral ischaemia. ( Ploen, R; Sun, L; Veltkamp, R; Zhou, W; Zorn, M, 2013)
"Dabigatran has the advantage of providing rapid and steady anticoagulation without requiring laboratory monitoring."2.49Dabigatran: a primer for neurosurgeons. ( Fugate, JE; Lanzino, G; McBane, RD; Rabinstein, AA, 2013)
"Stroke is a common disease, which is associated with high morbidity and high mortality."2.49[Anticoagulant therapy in stroke patients]. ( Grove, EL; Husted, SE; Kraglund, KL; Modrau, B, 2013)
"Warfarin-related intracerebral hemorrhage carries a particularly high risk of neurologic deterioration and death because of a high rate of hematoma expansion of about 50%."1.40Dabigatran-related intracerebral hemorrhage resulting in hematoma expansion. ( Damgaard, D; Simonsen, CZ; Steiner, T; Tietze, A, 2014)
"Contrast medium extravasation (CE) in intracerebral hemorrhage (ICH) is a marker of ongoing bleeding and a predictor of hematoma expansion."1.39Imaging of contrast medium extravasation in anticoagulation-associated intracerebral hemorrhage with dual-energy computed tomography. ( Dinkel, J; Foerch, C; Gupta, R; Hayakawa, K; Karatas, H; Lauer, A; Leung, W; Lo, EH; Schlunk, F; Steinmetz, H; Won, SY, 2013)
"Ischemic stroke was induced by transient middle cerebral artery occlusion (tMCAO) for 1 h or 3 h."1.38No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke. ( Bohmann, F; Foerch, C; Lindhoff-Last, E; Mirceska, A; Pfeilschifter, J; Pfeilschifter, W; Steinmetz, H, 2012)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's28 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, L1
Zhou, W2
Ploen, R1
Zorn, M2
Veltkamp, R3
Bauer, KA1
Won, SY1
Schlunk, F1
Dinkel, J1
Karatas, H1
Leung, W2
Hayakawa, K1
Lauer, A2
Steinmetz, H3
Lo, EH2
Foerch, C4
Gupta, R1
Simonsen, CZ1
Steiner, T1
Tietze, A1
Damgaard, D1
Yasaka, M2
Okada, Y2
Laroche, JP1
Hanon, O1
Faust, AC1
Peterson, EJ1
Schaefer, JH1
Wu, L1
Van Cott, EM1
Lok, J1
Whalen, M1
van Leyen, K1
van Ryn, J3
Konturek, P1
Hess, T1
Hana, A2
Berthold, C1
Gunness, VR1
Dooms, G1
Standhardt, H1
Koy, J1
Matgé, G1
Boecher-Schwarz, H1
Hertel, F1
Ammollo, CT1
Zaccaria, F1
Visino, F1
Testa, S1
Semeraro, N1
Colucci, M1
Tanoue, S1
Inamasu, J1
Yamada, M1
Toyama, H1
Hirose, Y1
Bouchard, J1
Ghannoum, M1
Bernier-Jean, A1
Williamson, D1
Kershaw, G1
Weatherburn, C1
Eris, JM1
Tran, H1
Patel, JP1
Roberts, DM1
Na, SY1
Mracsko, E1
Michota, F1
Schwarting, S1
Illanes, S1
Liesz, A1
Middelhoff, M1
Bendszus, M1
Heiland, S1
Casado Naranjo, I1
Portilla-Cuenca, JC1
Jiménez Caballero, PE1
Calle Escobar, ML1
Romero Sevilla, RM1
Dempfle, CE1
Hennerici, MG1
Diener, HC2
Eikelboom, J1
Granger, CB1
Hacke, W1
Moll, S1
Pfeilschifter, W2
Bohmann, F2
Baumgarten, P1
Mittelbronn, M1
Pfeilschifter, J2
Lindhoff-Last, E2
Kowey, PR1
Naccarelli, GV1
Fugate, JE1
Rabinstein, AA1
McBane, RD1
Lanzino, G1
Harenberg, J1
Marx, S1
Lip, GY1
Marder, VJ1
Wehling, M1
Weiss, C1
Mirceska, A1
Kraglund, KL1
Husted, SE1
Modrau, B1
Grove, EL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation[NCT03021928]Phase 3200 participants (Actual)Interventional2017-06-14Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for beta-alanine and Cerebral Hemorrhage

ArticleYear
Dabigatran, ROCKET atrial fibrillation, and beyond: basic science, mechanisms of agents, monitoring, and reversal.
    Stroke, 2013, Volume: 44, Issue:6 Suppl 1

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Coagulation

2013
[Novel oral anticoagulants and atrial fibrillation in the elderly].
    Geriatrie et psychologie neuropsychiatrie du vieillissement, 2013, Volume: 11, Issue:1 Suppl

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Benzimidazoles;

2013
[Gastrointestinal bleeding under treatment with new oral anticoagulants].
    MMW Fortschritte der Medizin, 2014, Feb-06, Volume: 156, Issue:2

    Topics: Administration, Oral; Aged; Anticoagulants; Arthroplasty, Replacement, Hip; Arthroplasty, Replacemen

2014
NOAC and intracerebral bleeding--presentation of four cases and review of the literature.
    Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg, 2014, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Dabiga

2014
Intracerebral hemorrhage: Pick your poison.
    Cleveland Clinic journal of medicine, 2010, Volume: 77, Issue:11

    Topics: Anticoagulants; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Chronic Disease; Dabigatran; Huma

2010
Dabigatran: a primer for neurosurgeons.
    World neurosurgery, 2013, Volume: 79, Issue:1

    Topics: Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation; Cerebral Hemorrhage; Dabigatran; Hum

2013
Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis.
    International angiology : a journal of the International Union of Angiology, 2012, Volume: 31, Issue:4

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cereb

2012
[Anticoagulant therapy in stroke patients].
    Ugeskrift for laeger, 2013, Jan-28, Volume: 175, Issue:5

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Brain Ischemia; Cerebral He

2013

Other Studies

20 other studies available for beta-alanine and Cerebral Hemorrhage

ArticleYear
Anticoagulation with dabigatran does not increase secondary intracerebral haemorrhage after thrombolysis in experimental cerebral ischaemia.
    Thrombosis and haemostasis, 2013, Volume: 110, Issue:1

    Topics: Animals; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Blood-Brain Barrier; Cerebral

2013
Imaging of contrast medium extravasation in anticoagulation-associated intracerebral hemorrhage with dual-energy computed tomography.
    Stroke, 2013, Volume: 44, Issue:10

    Topics: Animals; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation Factors; Cer

2013
Dabigatran-related intracerebral hemorrhage resulting in hematoma expansion.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:2

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cereb

2014
[Prevention and treatment of major bleeding during anticoagulation].
    Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11

    Topics: Administration, Oral; Alcohol Drinking; Anticoagulants; Benzimidazoles; beta-Alanine; Cerebral Hemor

2013
[New anticoagulants: stop or more?].
    Journal des maladies vasculaires, 2014, Volume: 39, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Anticoagulants; Antidotes; Benzimidazoles; beta-Alanine; Ce

2014
Management of dabigatran-associated intracerebral and intraventricular hemorrhage: a case report.
    The Journal of emergency medicine, 2014, Volume: 46, Issue:4

    Topics: Aged, 80 and over; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation Factors; Cerebral

2014
Translational insights into traumatic brain injury occurring during dabigatran or warfarin anticoagulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:5

    Topics: Animals; Anticoagulants; Benzimidazoles; beta-Alanine; Blood Coagulation; Blood Coagulation Factors;

2014
Influence of cell-associated tissue factor concentration on the anticoagulant activity of dabigatran. A possible explanation for the reduced incidence of intracranial bleeding.
    British journal of haematology, 2015, Volume: 168, Issue:6

    Topics: Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Coagulation; Case-Control St

2015
Does dabigatran increase the risk of delayed hematoma expansion in a rat model of collagenase-induced intracerebral hemorrhage?
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:2

    Topics: Animals; Antithrombins; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Collagenases; Dabigatran;

2015
Comparison of intermittent and continuous extracorporeal treatments for the enhanced elimination of dabigatran.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:3

    Topics: Aged; Aged, 80 and over; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation; Blood Coagu

2015
Idarucizumab Improves Outcome in Murine Brain Hemorrhage Related to Dabigatran.
    Annals of neurology, 2015, Volume: 78, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alan

2015
Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran.
    Stroke, 2011, Volume: 42, Issue:12

    Topics: Animals; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation; Brain; Cerebral Hemorrhage;

2011
Fatal intracerebral hemorrhage associated with administration of recombinant tissue plasminogen activator in a stroke patient on treatment with dabigatran.
    Cerebrovascular diseases (Basel, Switzerland), 2011, Volume: 32, Issue:6

    Topics: Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Cerebrovascular Circulation;

2011
Fibrinolytic treatment of acute ischemic stroke for patients on new oral anticoagulant drugs.
    Cerebrovascular diseases (Basel, Switzerland), 2011, Volume: 32, Issue:6

    Topics: Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Dabigatran; Fibrinolytic Agents; Humans; Male; St

2011
The king is dead (warfarin): direct thrombin and factor Xa inhibitors: the next Diadochian War?
    International journal of stroke : official journal of the International Stroke Society, 2012, Volume: 7, Issue:2

    Topics: Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Brain Ischemia; Cerebral Hemorrha

2012
Letter by Moll regarding article, "Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran".
    Stroke, 2012, Volume: 43, Issue:2

    Topics: Animals; Antithrombins; Benzimidazoles; beta-Alanine; Brain; Cerebral Hemorrhage

2012
Thrombolysis with recombinant tissue plasminogen activator under dabigatran anticoagulation in experimental stroke.
    Annals of neurology, 2012, Volume: 71, Issue:5

    Topics: Animals; Anticoagulants; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Dabigatran; Disease Mode

2012
The Food and Drug Administration decision not to approve the 110 mg dose of dabigatran: give us a way out.
    The American journal of medicine, 2012, Volume: 125, Issue:8

    Topics: Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Dabigatran;

2012
No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Administration, Oral; Animals; Antithrombins; Benzimidazoles; beta-Alanine; Blood Coagulation; Cereb

2012
[Management of intracranial hemorrhage during anticoagulant therapy with warfarin or novel anticoagulants].
    Rinsho shinkeigaku = Clinical neurology, 2012, Volume: 52, Issue:11

    Topics: Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Cerebral Hemorrhage; Dabigatran; Humans

2012