Page last updated: 2024-10-16

beta-alanine and Acute Kidney Injury

beta-alanine has been researched along with Acute Kidney Injury in 9 studies

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Excessive anticoagulation with warfarin can result in acute kidney injury (AKI) by causing glomerular hemorrhage and renal tubular obstruction by red blood cell (RBC) casts in some patients, especially in those with chronic kidney disease (CKD)."7.80Warfarin-related nephropathy is the tip of the iceberg: direct thrombin inhibitor dabigatran induces glomerular hemorrhage with acute kidney injury in rats. ( Brodsky, SV; Hebert, L; Nadasdy, G; Nadasdy, T; Qamri, Z; Rovin, B; Ryan, M; Satoskar, A; Ware, K; Wu, H, 2014)
"Excessive anticoagulation with warfarin can result in acute kidney injury (AKI) by causing glomerular hemorrhage and renal tubular obstruction by red blood cell (RBC) casts in some patients, especially in those with chronic kidney disease (CKD)."3.80Warfarin-related nephropathy is the tip of the iceberg: direct thrombin inhibitor dabigatran induces glomerular hemorrhage with acute kidney injury in rats. ( Brodsky, SV; Hebert, L; Nadasdy, G; Nadasdy, T; Qamri, Z; Rovin, B; Ryan, M; Satoskar, A; Ware, K; Wu, H, 2014)
"Dabigatran is a direct thrombin inhibitor indicated for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation."3.80[Patient with acute renal injury presenting dabigatran overdose: Hemodialysis for surgery]. ( Bachellerie, B; Conil, JM; Crognier, L; Fourcade, O; Georges, B; Ruiz, S; Seguin, T, 2014)
"This was a prospective observational study of ED patients under treatment with dabigatran or warfarin who were admitted with bleeding complications during a 6-month period."3.79Hemorrhagic complications in emergency department patients who are receiving dabigatran compared with warfarin. ( Berger, R; Chase, M; Ganetsky, M; Salhanick, SD, 2013)
"Dabigatran is a direct thrombin inhibitor that reduces the risk of systemic embolism in patients with nonvalvular atrial fibrillation."3.79A case of dabigatran-associated acute renal failure. ( Julius, CJ; Negrete, H; Roy, P; Sarac, E; Shafi, ST, 2013)
"A 66-year-old woman treated with dabigatran for atrial fibrillation developed acute renal failure and upper gastrointestinal bleeding."3.78Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment. ( Kouides, PA; Wychowski, MK, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fountzilas, C1
George, J1
Levine, R1
Berger, R1
Salhanick, SD1
Chase, M1
Ganetsky, M1
Ryan, M1
Ware, K1
Qamri, Z1
Satoskar, A1
Wu, H1
Nadasdy, G1
Rovin, B1
Hebert, L1
Nadasdy, T1
Brodsky, SV1
Holmes, D1
Bachellerie, B1
Ruiz, S1
Conil, JM1
Crognier, L1
Seguin, T1
Georges, B1
Fourcade, O1
Shafi, ST1
Negrete, H1
Roy, P1
Julius, CJ1
Sarac, E1
Wychowski, MK1
Kouides, PA1
Maddry, JK1
Amir, MK1
Sessions, D1
Heard, K1
Kaltenbach, JP1
Carone, FA1
Ganote, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Can Rivaroxaban Lead to Anticoagulation-Related Nephropathy?[NCT02900170]8 participants (Actual)Observational2016-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Anticoagulant-related Nephropathy in the Cohort

Primary endpoint - Incidence of ARN is the primary outcome of this study and this is based on a documentation of AKI (defined as an increase in baseline serum creatinine ≥ 0.3 mg/dL), in the absence of any other obvious etiology for the AKI identified after a standard clinical evaluation and work up by the patient's primary care physician, cardiologist or nephrologist. This incidence will be expressed as a percentage. (NCT02900170)
Timeframe: 6 months

InterventionPercentage of participants (Number)
Participants0

Other Studies

9 other studies available for beta-alanine and Acute Kidney Injury

ArticleYear
Dabigatran overdose secondary to acute kidney injury and amiodarone use.
    The New Zealand medical journal, 2013, Mar-01, Volume: 126, Issue:1370

    Topics: Acute Kidney Injury; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Antithrombins; Atrial Fi

2013
Hemorrhagic complications in emergency department patients who are receiving dabigatran compared with warfarin.
    Annals of emergency medicine, 2013, Volume: 61, Issue:4

    Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Antithrombins; Atrial Fibrillation; Benzi

2013
Warfarin-related nephropathy is the tip of the iceberg: direct thrombin inhibitor dabigatran induces glomerular hemorrhage with acute kidney injury in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2014, Volume: 29, Issue:12

    Topics: Acute Kidney Injury; Animals; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Dabigatra

2014
Acute kidney injury: renal hazards of anticoagulant therapy.
    Nature reviews. Nephrology, 2013, Volume: 9, Issue:11

    Topics: Acute Kidney Injury; Animals; Anticoagulants; Benzimidazoles; beta-Alanine; Dabigatran; Humans; Rats

2013
[Patient with acute renal injury presenting dabigatran overdose: Hemodialysis for surgery].
    Annales francaises d'anesthesie et de reanimation, 2014, Volume: 33, Issue:1

    Topics: Acute Kidney Injury; Aged, 80 and over; Alzheimer Disease; Antithrombins; Atrial Fibrillation; Benzi

2014
A case of dabigatran-associated acute renal failure.
    WMJ : official publication of the State Medical Society of Wisconsin, 2013, Volume: 112, Issue:4

    Topics: Acute Kidney Injury; Aged; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Biopsy;

2013
Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:4

    Topics: Acute Kidney Injury; Aged; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Creati

2012
Fatal dabigatran toxicity secondary to acute renal failure.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Aged; Antithrombins; Benzimidazoles; beta-Alanine; Dabigatran; Fatal Outcome; H

2013
Compounds protective against renal tubular necrosis induced by D-serine and D-2,3-diaminopropionic acid in the rat.
    Experimental and molecular pathology, 1982, Volume: 37, Issue:2

    Topics: Acute Kidney Injury; Alanine; Amino Acids; Animals; beta-Alanine; Kidney Tubular Necrosis, Acute; Ra

1982