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beta-alanine and Acute Coronary Syndrome

beta-alanine has been researched along with Acute Coronary Syndrome in 33 studies

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"After an acute coronary syndrome, patients remain at risk of recurrent ischaemic events, despite contemporary treatment, including aspirin and clopidogrel."9.15Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial. ( Budaj, A; Granger, CB; Khder, Y; Oldgren, J; Roberts, J; Siegbahn, A; Tijssen, JG; Van de Werf, F; Wallentin, L, 2011)
"Dabigatran is a direct, competitive inhibitor of thrombin recently approved for the prophylaxis of stroke and systemic embolism in patients with nonvalvular atrial fibrillation."8.90Increased risk of myocardial infarction with dabigatran: fact or fiction? ( Basile, E; Di Biase, L; Giglio, AF; Natale, A; Santangeli, P; Trotta, F, 2014)
"After an acute coronary syndrome, patients remain at risk of recurrent ischaemic events, despite contemporary treatment, including aspirin and clopidogrel."5.15Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial. ( Budaj, A; Granger, CB; Khder, Y; Oldgren, J; Roberts, J; Siegbahn, A; Tijssen, JG; Van de Werf, F; Wallentin, L, 2011)
" In Thrombin Receptor Antagonists for Clinical Event Reduction (TRA-CER), compared with standard care alone, bleeding complications including intracranial hemorrhage (ICH) were increased with the addition of vorapaxar, without efficacy benefit."4.90New antithrombotics for secondary prevention of acute coronary syndrome. ( Goto, S; Tomita, A, 2014)
"Dabigatran is a direct, competitive inhibitor of thrombin recently approved for the prophylaxis of stroke and systemic embolism in patients with nonvalvular atrial fibrillation."4.90Increased risk of myocardial infarction with dabigatran: fact or fiction? ( Basile, E; Di Biase, L; Giglio, AF; Natale, A; Santangeli, P; Trotta, F, 2014)
"There are concerns regarding increased risk of acute coronary syndrome with dabigatran."4.90Comparative coronary risks of apixaban, rivaroxaban and dabigatran: a meta-analysis and adjusted indirect comparison. ( Kwok, CS; Loke, YK; Pradhan, S; Yeong, JK, 2014)
" In the second part of the review is discussed higher incidence of myocardial infarction in controlled group in the trial comparing treatment of dabigatran with warfarin."4.90[Anticoagulant therapy in secondary prevention of coronary events]. ( Bultas, J, 2014)
"The novel oral anticoagulant drugs, comprising dabigatran, rivaroxaban, and apixaban, have emerged as compelling alternatives to vitamin K antagonists for stroke prevention in atrial fibrillation, and low‑molecular‑weight heparin for thromboprophylaxis following hip and knee arthroplasty."4.89Is there a role for novel oral anticoagulants in patients with an acute coronary syndrome? A review of the clinical trials. ( Darvish-Kazem, S; Douketis, JD; Liew, A, 2013)
"The new oral agents demonstrate several advantages over traditional anticoagulants, including administration at fixed doses and no requirement for routine coagulation monitoring On the basis of phase III clinical trials, rivaroxaban, apixaban and dabigatran etexilate have been approved in many countries for the prevention of venous thromboembolism after hip and knee replacement surgery."4.89Implications of new anticoagulants in primary practice. ( Eraso, LH; Merli, GJ; Perez, A, 2013)
"The original RE-LY (Randomized Evaluation of Long-term Anticoagulant Therapy) trial suggested a small increased risk of myocardial infarction (MI) with the use of dabigatran etexilate vs warfarin in patients with atrial fibrillation."4.88Dabigatran association with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials. ( Hernandez, AV; Uchino, K, 2012)
" The factor Xa inhibitor, rivaroxaban, has shown promising results in the treatment of acute coronary syndrome but is not yet approved for that indication."4.88What did we learn from new oral anticoagulant treatment? ( Esmon, CT, 2012)
"Warfarin and heparins have been the predominant anticoagulants used until the past decade."2.50The newer direct oral anticoagulants: a practical guide. ( Thachil, J, 2014)
"Warfarin has been the only available oral anticoagulant therapy for several decades."2.48Novel oral anticoagulation in management of venous thromboembolism, atrial fibrillation, and acute coronary syndrome. ( Khemasuwan, D; Suramaethakul, N, 2012)
" Clinicians are increasingly being challenged with making uncertain anticoagulant dosing decisions, as the optimal dosing strategy for most anticoagulants in the obese patient population remains unknown."2.47Anticoagulating obese patients in the modern era. ( Arya, R; Patel, JP; Roberts, LN, 2011)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's33 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fernández, D1
Penela, D1
Heras, M1
Bennaghmouch, N1
Ten Berg, JM1
Cove, CL1
Hylek, EM1
Goto, S1
Tomita, A1
Liew, A1
Darvish-Kazem, S1
Douketis, JD1
Giglio, AF1
Basile, E1
Santangeli, P1
Di Biase, L1
Trotta, F1
Natale, A1
Singh, D1
Gupta, K1
Vacek, JL1
Capodanno, D1
Angiolillo, DJ1
Loke, YK1
Pradhan, S1
Yeong, JK1
Kwok, CS1
Bassand, JP1
Thachil, J1
Chatterjee, S1
Sardar, P1
Giri, JS1
Ghosh, J1
Mukherjee, D1
Pontillo, D1
Patruno, N1
Messori, A1
Bultas, J1
Oldgren, J1
Budaj, A1
Granger, CB1
Khder, Y1
Roberts, J1
Siegbahn, A1
Tijssen, JG1
Van de Werf, F1
Wallentin, L1
Moser, M1
Bode, C1
Patel, JP1
Roberts, LN1
Arya, R1
Eerenberg, ES1
van Es, J1
Sijpkens, MK1
Büller, HR1
Kamphuisen, PW1
Redberg, RF1
Jacobs, JM1
Stessman, J1
Uchino, K1
Hernandez, AV1
Soff, GA1
Khemasuwan, D1
Suramaethakul, N1
Eikelboom, JW1
Weitz, JI1
Correia, LC1
Lopes, AA1
Kar, S1
Bhatt, DL1
Reed, SD1
Costopoulos, C1
Niespialowska-Steuden, M1
Kukreja, N1
Gorog, DA1
Esmon, CT1
Graf, L1
Tsakiris, DA1
Brasselet, C1
Duval, S1
Perez, A1
Eraso, LH1
Merli, GJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CHoosing Triple or Double therApy in the Era of nOac for patientS Undergoing PCI: the CHAOS a Multicenter Study.[NCT03558295]1,000 participants (Anticipated)Observational [Patient Registry]2018-05-01Recruiting
Comparison of Accidents and Their Circumstances With Oral Anticoagulants. The CACAO Study[NCT02376777]4,162 participants (Actual)Observational2014-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

22 reviews available for beta-alanine and Acute Coronary Syndrome

ArticleYear
[Contribution of the new oral anticoagulants to the treatment of acute coronary syndrome].
    Medicina clinica, 2012, Volume: 139 Suppl 2

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Azepines; Azetidines; Benzamides; Ben

2012
New oral anticoagulants after acute coronary syndrome.
    Best practice & research. Clinical haematology, 2013, Volume: 26, Issue:2

    Topics: Acute Coronary Syndrome; Administration, Oral; Aged; Anticoagulants; Benzimidazoles; beta-Alanine; C

2013
An updated review of target-specific oral anticoagulants used in stroke prevention in atrial fibrillation, venous thromboembolic disease, and acute coronary syndromes.
    Journal of the American Heart Association, 2013, Oct-23, Volume: 2, Issue:5

    Topics: Acute Coronary Syndrome; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatr

2013
New antithrombotics for secondary prevention of acute coronary syndrome.
    Clinical cardiology, 2014, Volume: 37, Issue:3

    Topics: Acute Coronary Syndrome; Anticoagulants; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Cor

2014
Is there a role for novel oral anticoagulants in patients with an acute coronary syndrome? A review of the clinical trials.
    Polskie Archiwum Medycyny Wewnetrznej, 2013, Volume: 123, Issue:11

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles;

2013
Increased risk of myocardial infarction with dabigatran: fact or fiction?
    Journal of cardiovascular medicine (Hagerstown, Md.), 2014, Volume: 15, Issue:1

    Topics: Acute Coronary Syndrome; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatra

2014
Anticoagulation and antiplatelet therapy in acute coronary syndromes.
    Cleveland Clinic journal of medicine, 2014, Volume: 81, Issue:2

    Topics: Acute Coronary Syndrome; Adenosine; Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine; Clopidogr

2014
Management of antiplatelet and anticoagulant therapy in patients with atrial fibrillation in the setting of acute coronary syndromes or percutaneous coronary interventions.
    Circulation. Cardiovascular interventions, 2014, Volume: 7, Issue:1

    Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzi

2014
Comparative coronary risks of apixaban, rivaroxaban and dabigatran: a meta-analysis and adjusted indirect comparison.
    British journal of clinical pharmacology, 2014, Volume: 78, Issue:4

    Topics: Acute Coronary Syndrome; Antithrombins; Benzimidazoles; beta-Alanine; Dabigatran; Factor Xa Inhibito

2014
Novel oral anticoagulants in acute coronary syndrome: re-evaluating the thrombin hypothesis.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, Mar-20, Volume: 9, Issue:11

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Azepines; Azetidines; Benzamides; Ben

2014
The newer direct oral anticoagulants: a practical guide.
    Clinical medicine (London, England), 2014, Volume: 14, Issue:2

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles;

2014
Treatment discontinuations with new oral agents for long-term anticoagulation: insights from a meta-analysis of 18 randomized trials including 101,801 patients.
    Mayo Clinic proceedings, 2014, Volume: 89, Issue:7

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Dabigat

2014
[Anticoagulant therapy in secondary prevention of coronary events].
    Vnitrni lekarstvi, 2014, Volume: 60, Issue:12

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Aspirin; Benzimidazoles; beta-Alanine

2014
Anticoagulating obese patients in the modern era.
    British journal of haematology, 2011, Volume: 155, Issue:2

    Topics: Acute Coronary Syndrome; Anticoagulants; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Dab

2011
Dabigatran association with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials.
    Archives of internal medicine, 2012, Mar-12, Volume: 172, Issue:5

    Topics: Acute Coronary Syndrome; Adult; Benzimidazoles; beta-Alanine; Dabigatran; Female; Humans; Incidence;

2012
A new generation of oral direct anticoagulants.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:3

    Topics: Acute Coronary Syndrome; Administration, Oral; Animals; Anticoagulants; Atrial Fibrillation; Benzimi

2012
Novel oral anticoagulation in management of venous thromboembolism, atrial fibrillation, and acute coronary syndrome.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2012, Volume: 18, Issue:5

    Topics: Acute Coronary Syndrome; Administration, Oral; Antithrombins; Atrial Fibrillation; Benzimidazoles; b

2012
Anticoagulants for the treatment of acute coronary syndrome in the era of new oral agents.
    Coronary artery disease, 2012, Volume: 23, Issue:6

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Antithrombins; Aspirin; Benzimidazole

2012
Novel oral anticoagulants in acute coronary syndrome.
    International journal of cardiology, 2013, Sep-10, Volume: 167, Issue:6

    Topics: Acute Coronary Syndrome; Administration, Oral; Animals; Anticoagulants; Benzimidazoles; beta-Alanine

2013
What did we learn from new oral anticoagulant treatment?
    Thrombosis research, 2012, Volume: 130 Suppl 1

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; B

2012
Anticoagulant treatment: the end of the old agents?
    Swiss medical weekly, 2012, Volume: 142

    Topics: Acute Coronary Syndrome; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Dabigatran; Dr

2012
Implications of new anticoagulants in primary practice.
    International journal of clinical practice, 2013, Volume: 67, Issue:2

    Topics: Acute Coronary Syndrome; Administration, Oral; Anticoagulants; Arthroplasty, Replacement, Hip; Arthr

2013

Trials

1 trial available for beta-alanine and Acute Coronary Syndrome

ArticleYear
Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial.
    European heart journal, 2011, Volume: 32, Issue:22

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Dose-

2011

Other Studies

10 other studies available for beta-alanine and Acute Coronary Syndrome

ArticleYear
Pitfalls of the interpretation of myocardial infarction data in patients on dabigatran treatment.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2015, Volume: 16, Issue:2

    Topics: Acute Coronary Syndrome; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Humans; M

2015
Cardiovascular safety of new oral anticoagulants: re-analysis of 27 randomized trials based on Bayesian network meta-analysis.
    British journal of clinical pharmacology, 2015, Volume: 80, Issue:1

    Topics: Acute Coronary Syndrome; Antithrombins; Benzimidazoles; beta-Alanine; Factor Xa Inhibitors; Humans;

2015
Redemption by RE-DEEM?
    European heart journal, 2011, Volume: 32, Issue:22

    Topics: Acute Coronary Syndrome; Benzimidazoles; beta-Alanine; Dabigatran; Female; Fibrinolytic Agents; Huma

2011
New anticoagulants: moving on from scientific results to clinical implementation.
    Annals of medicine, 2011, Volume: 43, Issue:8

    Topics: Acute Coronary Syndrome; Anticoagulants; Arthroplasty, Replacement, Hip; Atrial Fibrillation; Benzim

2011
Important data after drug approval: comment on "Dabigatran association with higher risk of acute coronary events".
    Archives of internal medicine, 2012, Mar-12, Volume: 172, Issue:5

    Topics: Acute Coronary Syndrome; Benzimidazoles; beta-Alanine; Dabigatran; Female; Humans; Male; Myocardial

2012
Dabigatran: do we have sufficient data?: comment on "Dabigatran association with higher risk of acute coronary events".
    Archives of internal medicine, 2012, Mar-12, Volume: 172, Issue:5

    Topics: Acute Coronary Syndrome; Benzimidazoles; beta-Alanine; Dabigatran; Female; Humans; Male; Myocardial

2012
Anticoagulation therapy. Dabigatran and risk of myocardial infarction.
    Nature reviews. Cardiology, 2012, Mar-13, Volume: 9, Issue:5

    Topics: Acute Coronary Syndrome; Benzimidazoles; beta-Alanine; Female; Humans; Male; Myocardial Infarction;

2012
Dabigatran and myocardial infarction: meta-illusion?
    Archives of internal medicine, 2012, May-28, Volume: 172, Issue:10

    Topics: Acute Coronary Syndrome; Benzimidazoles; beta-Alanine; Female; Humans; Male; Myocardial Infarction;

2012
How country-specific should a country-specific cost-effectiveness analysis be?
    European heart journal, 2013, Volume: 34, Issue:3

    Topics: Acute Coronary Syndrome; Adenosine; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanin

2013
[Role of new oral anticoagulants in interventional cardiology].
    Annales de cardiologie et d'angeiologie, 2012, Volume: 61, Issue:6

    Topics: Acute Coronary Syndrome; Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Benzi

2012