beta-2--deoxythioguanosine has been researched along with Vomiting* in 1 studies
1 other study(ies) available for beta-2--deoxythioguanosine and Vomiting
Article | Year |
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Phase I evaluation of beta-2'-deoxythioguanosine in pediatric patients with leukemia.
Thirty-one pediatric patients with acute leukemia who had relapsed on either 6-mercaptopurine or 6-thioguanine were treated with beta-2'-deoxythioguanosine, which was administered as an iv infusion every 12 hours for three or six doses every 2 weeks. Severe nausea and vomiting and urate nephropathy were the dose-limiting toxic effects. Therapeutic responses occurred in four of 24 children with acute lymphocytic leukemia and in two of seven with acute nonlymphoblastic leukemia. Topics: Acute Disease; Acute Kidney Injury; Child; Deoxyguanosine; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Nausea; Thionucleosides; Uric Acid; Vomiting | 1985 |