berotek has been researched along with Muscle Contraction in 42 studies
Fenoterol: A synthetic adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
fenoterol : A member of the class resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic exposure of human isolated bronchi to beta2-adrenergic agonists, especially fenoterol, potentiates smooth muscle contraction in response to endothelin-1 (ET-1), a peptide implicated in chronic inflammatory airway diseases." | 3.73 | Phosphodiesterase 4 inhibitors modulate beta2-adrenoceptor agonist-induced human airway hyperresponsiveness. ( Advenier, C; Devillier, P; Fagon, JY; Faisy, C; Guerot, E; Naline, E; Risse, PA, 2006) |
| "In the present study, we investigated the effect of fenoterol-induced constitutive beta(2)-adrenoceptor activity on muscarinic receptor agonist- and histamine-induced bovine tracheal smooth muscle contractions." | 3.71 | Effect of fenoterol-induced constitutive beta(2)-adrenoceptor activity on contractile receptor function in airway smooth muscle. ( de Vries, B; Meurs, H; Roffel, AF; Zaagsma, J, 2001) |
| "Clenbuterol treatment increased fiber cross-sectional area (CSA) by 6% and maximal isometric force (P(o)) by 20% in extensor digitorum longus (EDL) muscles, whereas fiber CSA in soleus muscles decreased by 3% and P(o) was unchanged, compared with untreated controls." | 1.31 | Beta 2-agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol. ( Gregorevic, P; Lynch, GS; Plant, DR; Ryall, JG; Sillence, MN, 2002) |
| "The isoproterenol effects were blocked by the antagonist propranolol." | 1.31 | Systemic and topical drug administration in the pig ureter: effect of phosphodiesterase inhibitors alpha1, beta and beta2-adrenergic receptor agonists and antagonists on the frequency and amplitude of ureteral contractions. ( Abel, D; Danuser, H; Mettler, D; Scholtysik, G; Studer, UE; Walter, B; Weiss, R, 2001) |
| "Scheduled chronic administration of beta 2-adrenoceptor agonist bronchodilators in patients with asthma recently has been reported to be associated with a worsening of symptoms and an increase in bronchial responsiveness." | 1.29 | Chronic exposure to a beta 2-adrenoceptor agonist increases the airway response to methacholine. ( Bloom, JW; Halonen, M; Palmer, JD; Witt-Enderby, PA; Yamamura, HI, 1993) |
| " At 72 h after the last administration of saline, fenoterol, and ovalbumin, the dose-response relationship between pulmonary resistance (RL) and nebulized acetylcholine (ACh) was measured." | 1.29 | Chronic fenoterol exposure increases in vivo and in vitro airway responses in guinea pigs. ( Bai, TR; Bramley, AM; McNamara, A; Paré, PD; Wang, ZL, 1994) |
| " The dose-response curves for these agonists were shifted slightly to the right when the amplitude of the twitch was increased up to twice its original size." | 1.28 | Dissociation constants and relative efficacies estimated from the functional antagonism of beta-adrenoceptor agonists on transmural stimulation in rat vas deferens. ( Diaz-Toledo, A; Jurkiewicz, A, 1990) |
| "6 Procaterol appears to be a particularly useful drug for detecting a functional population of beta 2-adrenoceptors in tissues, whether they are the minor or the predominant receptor sub-type present." | 1.27 | Responses to the beta 2-selective agonist procaterol of vascular and atrial preparations with different functional beta-adrenoceptor populations. ( O'Donnell, SR; Wanstall, JC, 1985) |
| " In the presence of increasing concentrations of ACh (2 X 10(-4) and 2 X 10(-3) mol/L), dose-response curves of the relaxant effect of F were shifted to the right (0." | 1.27 | Interaction between fenoterol, ipratropium, and acetylcholine on human isolated bronchus. ( Advenier, C; Bakdach, H; Matran, R; Naline, E; Toty, L, 1988) |
| "Clenbuterol (Contraspasmin, Spiropent) was used to treat threatened delivery in a dosage of three times 0." | 1.27 | [Effect of the oral beta-mimetic drug clenbuterol (Contraspasmin, Spiropent) and orally and intravenously administered Partusisten on the rheobase]. ( Jäger, KH; Niedner, W; Wagner, F; Weisbach, W, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (30.95) | 18.7374 |
| 1990's | 9 (21.43) | 18.2507 |
| 2000's | 13 (30.95) | 29.6817 |
| 2010's | 5 (11.90) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Pirotte, B | 1 |
| Ouedraogo, R | 1 |
| de Tullio, P | 1 |
| Khelili, S | 1 |
| Somers, F | 1 |
| Boverie, S | 1 |
| Dupont, L | 1 |
| Fontaine, J | 1 |
| Damas, J | 1 |
| Lebrun, P | 1 |
| Buonsanti, MF | 1 |
| Bertinaria, M | 1 |
| Stilo, AD | 1 |
| Cena, C | 1 |
| Fruttero, R | 1 |
| Gasco, A | 1 |
| Erdogan, BR | 1 |
| Yesilyurt, ZE | 1 |
| Arioglu-Inan, E | 1 |
| Michel, MC | 2 |
| Pozzoli, C | 1 |
| Bertini, S | 1 |
| Poli, E | 1 |
| Placenza, G | 1 |
| Menozzi, A | 1 |
| Birrell, MA | 1 |
| Bonvini, SJ | 1 |
| Wortley, MA | 1 |
| Buckley, J | 1 |
| Yew-Booth, L | 1 |
| Maher, SA | 1 |
| Dale, N | 1 |
| Dubuis, ED | 1 |
| Belvisi, MG | 1 |
| Duarte, T | 1 |
| Menezes-Rodrigues, FS | 1 |
| Godinho, RO | 1 |
| Dekkers, BG | 1 |
| Pehlic, A | 1 |
| Mariani, R | 1 |
| Bos, IS | 1 |
| Meurs, H | 4 |
| Zaagsma, J | 8 |
| Palea, S | 1 |
| Rekik, M | 1 |
| Rouget, C | 1 |
| Camparo, P | 1 |
| Botto, H | 1 |
| Rischmann, P | 1 |
| Lluel, P | 1 |
| Westfall, TD | 1 |
| Ryall, JG | 2 |
| Gregorevic, P | 1 |
| Plant, DR | 2 |
| Sillence, MN | 1 |
| Lynch, GS | 2 |
| Pinto, FM | 1 |
| Saulnier, JP | 1 |
| Faisy, C | 2 |
| Naline, E | 3 |
| Molimard, M | 1 |
| Prieto, L | 1 |
| Martin, JD | 1 |
| Emonds-Alt, X | 1 |
| Advenier, C | 3 |
| Candenas, ML | 1 |
| Oostendorp, J | 1 |
| Obels, PP | 1 |
| Terpstra, AR | 1 |
| Nelemans, SA | 1 |
| Schertzer, JD | 1 |
| Beitzel, F | 1 |
| Stupka, N | 1 |
| Maltaris, T | 1 |
| Dragonas, C | 1 |
| Hoffmann, I | 1 |
| Mueller, A | 1 |
| Schild, RL | 1 |
| Schmidt, W | 1 |
| Beckmann, MW | 1 |
| Dittrich, R | 1 |
| Risse, PA | 1 |
| Guerot, E | 1 |
| Fagon, JY | 1 |
| Devillier, P | 1 |
| O'Donnell, SR | 2 |
| Wanstall, JC | 2 |
| Mian, MA | 1 |
| Malta, E | 1 |
| Raper, C | 1 |
| Urban, J | 1 |
| Krygicz, J | 1 |
| Diether, K | 1 |
| Barnikol, WK | 1 |
| Ten Berge, RE | 1 |
| Weening, EC | 1 |
| Roffel, AF | 5 |
| Witt-Enderby, PA | 1 |
| Yamamura, HI | 1 |
| Halonen, M | 1 |
| Palmer, JD | 1 |
| Bloom, JW | 1 |
| Wang, ZL | 2 |
| Bramley, AM | 1 |
| McNamara, A | 1 |
| Paré, PD | 2 |
| Bai, TR | 2 |
| Lemoine, H | 2 |
| Worth, H | 2 |
| Reinhardt, D | 2 |
| Walker, BA | 1 |
| Weir, TD | 1 |
| Yarema, MC | 1 |
| Roberts, CR | 1 |
| Okazawa, M | 1 |
| Huang, Y | 1 |
| Kwok, KH | 1 |
| Carcano, R | 1 |
| Belloli, C | 1 |
| Arioli, F | 1 |
| Beretta, C | 1 |
| Mak, JC | 1 |
| Katsunuma, T | 1 |
| Elzinga, CR | 2 |
| Barnes, PJ | 1 |
| de Vries, B | 3 |
| Hoiting, BH | 1 |
| de Vries, MM | 1 |
| Kooistra, JM | 1 |
| Danuser, H | 1 |
| Weiss, R | 1 |
| Abel, D | 1 |
| Walter, B | 1 |
| Scholtysik, G | 1 |
| Mettler, D | 1 |
| Studer, UE | 1 |
| Kords, H | 1 |
| Overlack, C | 1 |
| Köhl, A | 1 |
| Diaz-Toledo, A | 1 |
| Jurkiewicz, A | 1 |
| van Amsterdam, RG | 1 |
| Brouwer, F | 1 |
| Kolbeck, RC | 1 |
| Chaudhary, BA | 1 |
| Speir, WA | 1 |
| Peiker, G | 1 |
| Mares, J | 1 |
| Hasanova, M | 1 |
| Glöckner, R | 1 |
| Suzuki, S | 1 |
| Numata, H | 1 |
| Sano, F | 1 |
| Yoshiike, Y | 1 |
| Miyashita, A | 1 |
| Okubo, T | 1 |
| Goldie, RG | 1 |
| Spina, D | 1 |
| Paterson, JW | 1 |
| Matran, R | 1 |
| Toty, L | 1 |
| Bakdach, H | 1 |
| Weisbach, W | 1 |
| Niedner, W | 1 |
| Wagner, F | 1 |
| Jäger, KH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005279] | 0 participants | Observational | 1971-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
42 other studies available for berotek and Muscle Contraction
| Article | Year |
|---|---|
3-Alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides structurally related to diazoxide and pinacidil as potassium channel openers acting on vascular smooth muscle cells: design, synthesis, and pharmacological evaluation.
Topics: Animals; Aorta; Cyclic S-Oxides; Diazoxide; Drug Design; Female; Guinea Pigs; Ileum; In Vitro Techni | 2000 |
Nitric oxide donor beta2-agonists: furoxan derivatives containing the fenoterol moiety and related furazans.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Antioxidants; Aorta; Fenoterol; Guinea Pigs; In Vitro | 2007 |
Validation of Fenoterol to Study β2-Adrenoceptor Function in the Rat Urinary Bladder.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Aminophenols; Animals; Carbachol; | 2022 |
Relaxing effects of clenbuterol, ritodrine, salbutamol and fenoterol on the contractions of horse isolated bronchi induced by different stimuli.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Bronchi; Bronchodilator Agents; Clenbuterol | 2020 |
Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; | 2014 |
The role of adenylyl cyclase isoform 6 in β-adrenoceptor signalling in murine airways.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dinoprostone; Eth | 2015 |
Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.
Topics: Adenosine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Clenbuterol; Colf | 2012 |
Glucocorticosteroids and β₂-adrenoceptor agonists synergize to inhibit airway smooth muscle remodeling.
Topics: Adrenergic beta-2 Receptor Agonists; Airway Remodeling; Androstadienes; Animals; Budesonide; Cattle; | 2012 |
Fenoterol functionally activates the β₃-adrenoceptor in human urinary bladder, comparison with rat and mouse: implications for drug discovery.
Topics: Adrenergic beta-Agonists; Aged; Animals; Drug Discovery; Electric Stimulation; Female; Fenoterol; Hu | 2012 |
Beta 2-agonist fenoterol has greater effects on contractile function of rat skeletal muscles than clenbuterol.
Topics: Adrenal Glands; Adrenergic beta-Agonists; Animals; Clenbuterol; Fenoterol; Heart; Male; Muscle Contr | 2002 |
SR 142801, a tachykinin NK(3) receptor antagonist, prevents beta(2)-adrenoceptor agonist-induced hyperresponsiveness to neurokinin A in guinea-pig isolated trachea.
Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Culture Techn | 2002 |
Modulation of beta2- and beta3-adrenoceptor-mediated relaxation of rat oesophagus smooth muscle by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Esophagus; E | 2004 |
Beta2-agonist administration increases sarcoplasmic reticulum Ca2+-ATPase activity in aged rat skeletal muscle.
Topics: Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Calcium; Calcium-Transporting ATPases; | 2005 |
The extracorporeal perfusion of the swine uterus as an experimental model: The effect of tocolytic drugs.
Topics: Animals; Dinoprostone; Female; Fenoterol; Models, Animal; Muscle Contraction; Myometrium; Organ Cult | 2006 |
Phosphodiesterase 4 inhibitors modulate beta2-adrenoceptor agonist-induced human airway hyperresponsiveness.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; | 2006 |
Pharmacological approaches to the characterization of beta-adrenoreceptor populations in tissues.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cats; Female; Fenoterol; Guinea Pigs; Male; Muscle C | 1981 |
An homogeneous population of beta 1-adrenoceptors subserves inhibitory responses in guinea-pig ileal preparations.
Topics: Animals; Atenolol; Fenoterol; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Muscle Contrac | 1984 |
[Effect of beta-mimetics on the contractile reactivity of isolated human placental blood vessels].
Topics: Arteries; Culture Techniques; Depression, Chemical; Ethanolamines; Female; Fenoterol; Humans; Muscle | 1983 |
[The broncholytic effect of buffers applied by inhalation. A new pharmacological concept (author's transl)].
Topics: Adult; Bronchodilator Agents; Buffers; Fenoterol; Humans; Muscle Contraction; Muscle, Smooth | 1982 |
Beta 2- but not beta 3-adrenoceptors mediate prejunctional inhibition of non-adrenergic non-cholinergic contraction of guinea pig main bronchi.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Dose-Response Relationship, Drug; Electric St | 1995 |
Chronic exposure to a beta 2-adrenoceptor agonist increases the airway response to methacholine.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bronchi; Female; Fenoterol; Male; Methacholine Compoun | 1993 |
Chronic fenoterol exposure increases in vivo and in vitro airway responses in guinea pigs.
Topics: Aerosols; Analysis of Variance; Animals; Bronchi; Dose-Response Relationship, Drug; Fenoterol; Guine | 1994 |
[Pharmacologic characterization of formoterol in comparison with isoprenaline, fenoterol and salbutamol in tracheal muscle strips and lung membranes of the guinea pig].
Topics: Airway Resistance; Albuterol; Animals; Carbachol; Culture Techniques; Dose-Response Relationship, Dr | 1993 |
Effect of chronic antigen and beta 2 agonist exposure on airway remodeling in guinea pigs.
Topics: Adrenergic beta-Agonists; Animals; Antigens; Bromodeoxyuridine; Bronchi; Cell Division; Fenoterol; G | 1995 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotox | 1997 |
Suitability of the old fowl rectal caecum preparation for investigating the selectivity of beta-adrenergic drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cecum; Chickens; Clenbuterol; Dobutami | 1998 |
Up-regulation of airway smooth muscle histamine H(1) receptor mRNA, protein, and function by beta(2)-adrenoceptor activation.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Northern; Cattle; Fenoterol; Glucocorticoids; Muscle Co | 2000 |
Beta-agonist-induced constitutive beta(2)-adrenergic receptor activity in bovine tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cattle; Dose-Response Relationship, | 2000 |
Effects of fenoterol on beta-adrenoceptor and muscarinic M2 receptor function in bovine tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cattle; Drug Interact | 2001 |
Systemic and topical drug administration in the pig ureter: effect of phosphodiesterase inhibitors alpha1, beta and beta2-adrenergic receptor agonists and antagonists on the frequency and amplitude of ureteral contractions.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Ag | 2001 |
Effect of fenoterol-induced constitutive beta(2)-adrenoceptor activity on contractile receptor function in airway smooth muscle.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Cattle; Dose-Response Relationship, Drug; Drug Interac | 2001 |
[Influence of fenoterol of cAMP levels and motility on the rat uterus in vitro (author's transl)].
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Ethanolamines; Female; Fenoterol; Muscle Cont | 1975 |
Formoterol, fenoterol, and salbutamol as partial agonists for relaxation of maximally contracted guinea pig tracheae: comparison of relaxation with receptor binding.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Animals; Binding, Competitive; Carbachol; Cu | 1992 |
Dissociation constants and relative efficacies estimated from the functional antagonism of beta-adrenoceptor agonists on transmural stimulation in rat vas deferens.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Dose-Response Relationship, Drug; Electric Stimulation | 1990 |
Analysis of the beta-adrenoceptor mediated inhibition of IgG1 and IgE dependent guinea-pig anaphylactic tracheal smooth muscle contraction.
Topics: Anaphylaxis; Animals; Chromones; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-ace | 1989 |
Effect of glucocorticoids on the response of airway smooth muscle to catecholamine and resorcinol beta-agonists.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Fenoterol; Glucocorticoids; Guinea Pigs; Hydro | 1989 |
[The effect of partusisten, dilatol, papaverine and magnesium sulfate on uterine smooth muscle in vitro].
Topics: Animals; Female; Fenoterol; In Vitro Techniques; Magnesium Sulfate; Muscle Contraction; Muscle, Smoo | 1989 |
Effects and mechanism of fenoterol on fatigued canine diaphragm.
Topics: Aminophylline; Animals; Bucladesine; Diaphragm; Dogs; Electric Stimulation; Fatigue; Fenoterol; Musc | 1988 |
Responses to the beta 2-selective agonist procaterol of vascular and atrial preparations with different functional beta-adrenoceptor populations.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Atenolol; Coronary Vessels; Ethanolamines; Female; Fenoter | 1985 |
Beta agonist-induced desensitization in pig bronchus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Bronchi; Colforsi | 1986 |
Interaction between fenoterol, ipratropium, and acetylcholine on human isolated bronchus.
Topics: Acetylcholine; Atropine Derivatives; Bronchi; Dose-Response Relationship, Drug; Drug Interactions; F | 1988 |
[Effect of the oral beta-mimetic drug clenbuterol (Contraspasmin, Spiropent) and orally and intravenously administered Partusisten on the rheobase].
Topics: Administration, Oral; Clenbuterol; Electric Stimulation; Ethanolamines; Female; Fenoterol; Humans; I | 1985 |