berkelic-acid has been researched along with Ovarian-Neoplasms* in 1 studies
1 other study(ies) available for berkelic-acid and Ovarian-Neoplasms
Article | Year |
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Scalable total synthesis of (-)-berkelic acid by using a protecting-group-free strategy.
Supply chain: the polycyclic core of (-)-berkelic acid (1) was constructed in just one step from very simple starting materials. The total synthesis of 1 involves a seven-step linear sequence. Protection/deprotection steps were avoided and all but the last step were performed on a gram scale. This synthesis could solve the supply problem associated with the exhaustion of the natural source. Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Ovarian Neoplasms; Spiro Compounds; Stereoisomerism | 2012 |