berkelic-acid and Ovarian-Neoplasms

berkelic-acid has been researched along with Ovarian-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for berkelic-acid and Ovarian-Neoplasms

ArticleYear
Scalable total synthesis of (-)-berkelic acid by using a protecting-group-free strategy.
    Angewandte Chemie (International ed. in English), 2012, May-14, Volume: 51, Issue:20

    Supply chain: the polycyclic core of (-)-berkelic acid (1) was constructed in just one step from very simple starting materials. The total synthesis of 1 involves a seven-step linear sequence. Protection/deprotection steps were avoided and all but the last step were performed on a gram scale. This synthesis could solve the supply problem associated with the exhaustion of the natural source.

    Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Ovarian Neoplasms; Spiro Compounds; Stereoisomerism

2012