Page last updated: 2024-10-23

berberine and Weight Gain

berberine has been researched along with Weight Gain in 14 studies

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"This study suggests that berberine is a potential weight loss and weight maintenance drug for patients with schizophrenia."9.51Berberine treatment for weight gain in patients with schizophrenia by regulating leptin rather than adiponectin. ( Jia, Q; Li, J; Li, M; Liu, Y; Qiu, Y; Zhang, J; Zhang, Y; Zhao, Y, 2022)
"The aim of this study was to evaluate the efficacy and safety of berberine as an adjuvant in treating antipsychotic-associated weight gain and metabolic syndrome."9.51Adjunctive berberine reduces antipsychotic-associated weight gain and metabolic syndrome in patients with schizophrenia: a randomized controlled trial. ( Chan, M; Chen, EYH; Feng, Y; Han, F; Lai, WH; Lam, M; Lee, CK; Lee, EHM; Liu, L; Man, SC; Ng, RMK; Qin, Z; Wong, HK; Wong, TL; Zhang, ZJ, 2022)
"To elucidate the protective effect of berberine on olanzapine induced-metabolic syndrome."7.91Berberine attenuates olanzapine induced-metabolic syndrome. ( Al-Gareeb, AI; Al-Kuraishy, HM; Al-Naimi, MS; Rasheed, HA, 2019)
"Olanzapine is a first line medication for the treatment of schizophrenia, but it is also one of the atypical antipsychotics carrying the highest risk of weight gain."7.80Metformin and berberine prevent olanzapine-induced weight gain in rats. ( Davies, GE; Davies, PS; Droke, EA; Ehli, EA; Hu, Y; Nowotny, D; Soundy, TJ; Young, AJ, 2014)
"This study suggests that berberine is a potential weight loss and weight maintenance drug for patients with schizophrenia."5.51Berberine treatment for weight gain in patients with schizophrenia by regulating leptin rather than adiponectin. ( Jia, Q; Li, J; Li, M; Liu, Y; Qiu, Y; Zhang, J; Zhang, Y; Zhao, Y, 2022)
"The aim of this study was to evaluate the efficacy and safety of berberine as an adjuvant in treating antipsychotic-associated weight gain and metabolic syndrome."5.51Adjunctive berberine reduces antipsychotic-associated weight gain and metabolic syndrome in patients with schizophrenia: a randomized controlled trial. ( Chan, M; Chen, EYH; Feng, Y; Han, F; Lai, WH; Lam, M; Lee, CK; Lee, EHM; Liu, L; Man, SC; Ng, RMK; Qin, Z; Wong, HK; Wong, TL; Zhang, ZJ, 2022)
"Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic manifestation of metabolic syndrome."5.46Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease. ( Cang, Z; Lu, Y; Nie, X; Sun, H; Wang, N; Zhao, L, 2017)
"To elucidate the protective effect of berberine on olanzapine induced-metabolic syndrome."3.91Berberine attenuates olanzapine induced-metabolic syndrome. ( Al-Gareeb, AI; Al-Kuraishy, HM; Al-Naimi, MS; Rasheed, HA, 2019)
"Berberine could reduce weight gain and lipolysis in the high-fat diet-fed group."3.83Modulation of Microbiota-Gut-Brain Axis by Berberine Resulting in Improved Metabolic Status in High-Fat Diet-Fed Rats. ( Cang, Z; Cheng, J; Lu, Y; Nie, X; Sun, H; Wang, N; Xia, F; Zhai, H; Zhao, L; Zhu, C, 2016)
"Epiberberine was found to be associated with the inhibition of weight gain."1.72Toxicity and toxicokinetics of the ethanol extract of Zuojin formula. ( Gao, Y; Li, L; Li, Y; Liu, X; Shan, D; Wang, Q; Wang, S; Yang, Z; Zhang, T; Zhang, Y, 2022)
"Berberine has been reported to have pharmacological activity in adipose tissue to anti-obesity, while the mechanism remains unclear."1.62Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway. ( Cao, L; He, Z; Jiang, X; Kong, J; Li, N; Ma, G; Song, X; Wang, Z; Wen, D; Xu, Y; Yang, F; Yu, T; Yu, Y; Zheng, L, 2021)
"Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic manifestation of metabolic syndrome."1.46Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease. ( Cang, Z; Lu, Y; Nie, X; Sun, H; Wang, N; Zhao, L, 2017)
" lycium extracts as well as berberine were not lethal up to dosage of 2000 mg/kg body weight."1.40In vivo anticoccidial activity of berberine [18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium]--an isoquinoline alkaloid present in the root bark of Berberis lycium. ( Ahad, S; Chishti, MZ; Johri, RK; Kamili, AN; Malik, TA; Tanveer, S, 2014)
"Berberine treatments were either provided in preventive or therapeutic mode respectively."1.39Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study. ( Chitra, P; Manikandan, R; Saiprasad, G; Sudhandiran, G, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (64.29)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Qiu, Y1
Li, M2
Zhang, Y3
Liu, Y1
Zhao, Y2
Zhang, J2
Jia, Q1
Li, J1
Chan, M1
Qin, Z1
Man, SC1
Lam, M1
Lai, WH1
Ng, RMK1
Lee, CK1
Wong, TL1
Lee, EHM1
Wong, HK1
Feng, Y1
Liu, L1
Han, F1
Chen, EYH1
Zhang, ZJ1
Wang, S1
Zhang, T1
Liu, X1
Yang, Z1
Li, L1
Shan, D1
Gao, Y1
Li, Y2
Wang, Q1
Urasaki, Y1
Le, TT1
Al-Naimi, MS1
Rasheed, HA1
Al-Kuraishy, HM1
Al-Gareeb, AI1
Xu, Y1
Yu, T1
Ma, G1
Zheng, L1
Jiang, X1
Yang, F1
Wang, Z1
Li, N1
He, Z1
Song, X1
Wen, D1
Kong, J1
Yu, Y1
Cao, L1
Chitra, P1
Saiprasad, G1
Manikandan, R1
Sudhandiran, G1
Malik, TA1
Kamili, AN1
Chishti, MZ1
Tanveer, S1
Ahad, S1
Johri, RK1
Hu, Y2
Young, AJ1
Ehli, EA1
Nowotny, D1
Davies, PS1
Droke, EA1
Soundy, TJ1
Davies, GE2
Sun, H2
Wang, N2
Cang, Z2
Zhu, C1
Zhao, L3
Nie, X2
Cheng, J1
Xia, F1
Zhai, H1
Lu, Y2
Zhao, X1
Tong, N1
Liao, X1
Wang, E1
Li, Z1
Luo, Y1
Zuo, H1
Zhang, X1
Zhang, M1
Pang, X1
Xu, J1
Kang, C1
Zhang, C1
Zhang, Z1
Li, X1
Ning, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Randomized, Placebo-controlled Trial of Berberine as an Adjuvant to Treat Antipsychotic-induced Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders[NCT02983188]Phase 2/Phase 3113 participants (Actual)Interventional2018-04-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for berberine and Weight Gain

ArticleYear
Berberine treatment for weight gain in patients with schizophrenia by regulating leptin rather than adiponectin.
    Asian journal of psychiatry, 2022, Volume: 67

    Topics: Adiponectin; Antipsychotic Agents; Berberine; Body Mass Index; Double-Blind Method; Humans; Leptin;

2022
Adjunctive berberine reduces antipsychotic-associated weight gain and metabolic syndrome in patients with schizophrenia: a randomized controlled trial.
    Psychiatry and clinical neurosciences, 2022, Volume: 76, Issue:3

    Topics: Antipsychotic Agents; Berberine; Double-Blind Method; Humans; Metabolic Syndrome; Schizophrenia; Wei

2022

Other Studies

12 other studies available for berberine and Weight Gain

ArticleYear
Toxicity and toxicokinetics of the ethanol extract of Zuojin formula.
    BMC complementary medicine and therapies, 2022, Aug-15, Volume: 22, Issue:1

    Topics: Alkaloids; Animals; Berberine; Body Weight; Coptis; Drugs, Chinese Herbal; Ethanol; Female; Male; Ra

2022
A Composition of Phytonutrients for Glycemic and Weight Management.
    Nutrients, 2022, Sep-14, Volume: 14, Issue:18

    Topics: Acrolein; Animals; Berberine; Blood Glucose; Curcumin; Diabetes Mellitus; Disease Models, Animal; Fa

2022
Berberine attenuates olanzapine induced-metabolic syndrome.
    JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69(Suppl 3), Issue:8

    Topics: Animals; Berberine; Biomarkers; Insulin Resistance; Male; Metabolic Syndrome; Olanzapine; Prospectiv

2019
Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway.
    International journal of biological sciences, 2021, Volume: 17, Issue:12

    Topics: Adipose Tissue, Brown; AMP-Activated Protein Kinases; Animals; Berberine; Blotting, Western; Body We

2021
Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: a biphasic experimental study.
    Toxicology letters, 2013, May-23, Volume: 219, Issue:2

    Topics: Animals; Antimetabolites; Berberine; Bleomycin; Blotting, Western; Bronchoalveolar Lavage Fluid; Col

2013
In vivo anticoccidial activity of berberine [18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium]--an isoquinoline alkaloid present in the root bark of Berberis lycium.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Apr-15, Volume: 21, Issue:5

    Topics: Animals; Berberine; Berberis; Chickens; Coccidiosis; Coccidiostats; Male; Parasite Egg Count; Phytot

2014
Metformin and berberine prevent olanzapine-induced weight gain in rats.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Adipose Tissue, White; Animals; Antipyretics; Benzodiazepines; Berberine; Eating; Female; Ion Channe

2014
Modulation of Microbiota-Gut-Brain Axis by Berberine Resulting in Improved Metabolic Status in High-Fat Diet-Fed Rats.
    Obesity facts, 2016, Volume: 9, Issue:6

    Topics: Animals; Berberine; Brain; Diet, High-Fat; Energy Metabolism; Gastrointestinal Microbiome; Glucagon-

2016
Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease.
    BMC endocrine disorders, 2017, Feb-28, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Carbohydrate Metabolism; Diet, High-Fat

2017
Berberine inhibits adipogenesis in high-fat diet-induced obesity mice.
    Fitoterapia, 2010, Volume: 81, Issue:5

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; Berberine; Blood Glucose; Cholesterol; Diet, Atherogenic; Dieta

2010
Berberine attenuates doxorubicin-induced cardiotoxicity in mice.
    The Journal of international medical research, 2011, Volume: 39, Issue:5

    Topics: Animals; Berberine; Cardiotonic Agents; Cardiotoxins; Doxorubicin; Electrocardiography; Female; L-La

2011
Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Adiposity; Animals; Berberine; Diet, High-Fat; Fatty Acids, Volatile; Feces; Feeding Behavior; Gastr

2012