Page last updated: 2024-10-23

berberine and Ventricular Fibrillation

berberine has been researched along with Ventricular Fibrillation in 7 studies

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"The effects of berberine (Ber 5 mg/kg iv) on ventricular tachyarrhythmias and electrophysiologic consequences in both normal and ischemic myocardium were studied in the open-chest dogs subjected to programmed electrical stimulation (PES) and intimal surface anodal direct current stimulation of the circumflex coronary artery on 5-8 d after acute myocardial infarction."7.67[Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction]. ( Cao, HY; Li, Q; Xu, Z, 1989)
" We hypothesized that CPU86017, derived from berberine, which possesses multi-channel blocking activity, could suppress inflammatory factors, resulting in inhibition of over-expression of ether-a-go-go (ERG) and an augmented incidence of ventricular fibrillation (VF) in ischaemia/reperfusion (I/R)."3.74Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent. ( Dai, DZ; Dai, Y; Du, RH; Tang, WH; Yi, HW, 2008)
"Electric stimulation and drug-induced ventricular fibrillation (VF), monophasic action potentials (MAP), and triggered activity were studied before and after administration of tetrahydroberberine (THB) in rabbits, rats or guinea pigs."3.68Antifibrillatory effect of tetrahydroberberine. ( Li, DX; Sun, AY, 1993)
"The effects of berberine (Ber 5 mg/kg iv) on ventricular tachyarrhythmias and electrophysiologic consequences in both normal and ischemic myocardium were studied in the open-chest dogs subjected to programmed electrical stimulation (PES) and intimal surface anodal direct current stimulation of the circumflex coronary artery on 5-8 d after acute myocardial infarction."3.67[Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction]. ( Cao, HY; Li, Q; Xu, Z, 1989)
"It is active in suppressing arrhythmias in several animal models."2.43CPU86017: a novel Class III antiarrhythmic agent with multiple actions at ion channels. ( Dai, DZ, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Du, RH1
Yi, HW1
Dai, DZ4
Tang, WH1
Dai, Y3
Na, T1
Huang, ZJ1
Zhang, Y1
Sun, AY1
Li, DX1
Xu, Z1
Cao, HY1
Li, Q1
Fang, DC1
Zong, XG1
Jin, MW1
Zhou, SM1
Jiang, MX1

Reviews

2 reviews available for berberine and Ventricular Fibrillation

ArticleYear
Induced ion currents and the endothelin pathway as targets for anti-arrhythmic agents.
    Current opinion in investigational drugs (London, England : 2000), 2008, Volume: 9, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Berberine; Death, Sudden, Cardiac; Endothelin

2008
CPU86017: a novel Class III antiarrhythmic agent with multiple actions at ion channels.
    Cardiovascular drug reviews, 2006,Summer, Volume: 24, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Berberine; Death, Sudden, Cardiac; Humans; Io

2006

Other Studies

5 other studies available for berberine and Ventricular Fibrillation

ArticleYear
Inflammatory factors that contribute to upregulation of ERG and cardiac arrhythmias are suppressed by CPU86017, a class III antiarrhythmic agent.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Aspartic Acid Endopeptidases; Berberine; Cardiomegaly

2008
Abrupt changes in FKBP12.6 and SERCA2a expression contribute to sudden occurrence of ventricular fibrillation on reperfusion and are prevented by CPU86017.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Aspartic Acid Endopeptidases; Berberine; Calcium; Cardiomyopathies;

2007
Antifibrillatory effect of tetrahydroberberine.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:4

    Topics: Aconitine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barium Compound

1993
[Protective effects of berberine on spontaneous ventricular fibrillation in dogs after myocardial infarction].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:4

    Topics: Animals; Berberine; Berberine Alkaloids; Dogs; Female; Male; Myocardial Infarction; Procainamide; Ve

1989
[Antifibrillatory effect of berberine].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:4

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Berberine; Berberine Alkaloids; Cats; Dose-Respo

1986