Page last updated: 2024-10-23

berberine and Stomach Neoplasms

berberine has been researched along with Stomach Neoplasms in 17 studies

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
"Gastric cancer is a prevalent malignant tumor that seriously affects human health."1.72Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6. ( Fan, J; Huang, L; Li, X; Ren, L; Xu, M; Ye, X; Zhou, L, 2022)
"Treatment with berberine triggered cell autophagy, as demonstrated by the punctuate distribution of monodansylcadaverine staining and GFP-LC3, as well as the LC3-II, Beclin-1 and p-ULK1 promotion, and p62 degradation."1.56Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways. ( Cao, S; Duan, J; He, X; Jiang, B; Kang, N; Qiu, F; Sun, Y; Wang, X; Yu, Y; Zhang, Q, 2020)
"Berberine (BBR) is a traditional Chinese medicine normally used for gastroenteritis, and recent research found that it could fight against tumors."1.48Integration of microRNA-mRNA profiles and pathway analysis of plant isoquinoline alkaloid berberine in SGC-7901 gastric cancers cells. ( Chen, J; Li, K; Qiu, L; Yang, Y; Zhang, J; Zhang, N, 2018)
"Gastric cancer is the second leading cause of cancer-associated mortality worldwide."1.43MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo. ( Li, HL; Shi, HL; Wu, H; Wu, XJ; Zhang, BB, 2016)
"Berberine was found to inhibit growth in GC cell lines and to induce apoptosis."1.43Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer. ( Cai, X; Cao, H; Chen, Z; Dong, J; Fan, D; Hao, J; Jin, T; Lu, D; Nie, Y; Wang, J; Wang, R; Yang, S; Zhang, S, 2016)
"Berberine was more effective in inhibiting survivin expression as compared to other herbal agents."1.42Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil. ( Bharti, AC; Dwivedi, M; Mahata, S; Mehrotra, R; Misra, SP; Misra, V; Pandey, A; Tripathi, SC; Vishnoi, K, 2015)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's8 (47.06)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Xu, M1
Ren, L1
Fan, J1
Huang, L1
Zhou, L1
Li, X1
Ye, X1
Peng, Z1
Wangmu, T1
Li, L1
Han, G1
Huang, D1
Yi, P1
Liu, Q1
Tang, J2
Chen, S1
Hu, S1
Shen, C2
Xiang, J1
Chen, N2
Wang, J2
Ma, X1
Zhang, Y1
Zeng, J2
Zhao, M1
Yang, Y2
Nian, Q1
Xiao, X1
Liao, W1
Zheng, Q1
Zhang, G1
Gong, D1
Wen, Y1
Zhang, Q1
Wang, X1
Cao, S1
Sun, Y1
He, X1
Jiang, B1
Yu, Y1
Duan, J1
Qiu, F1
Kang, N1
Zhang, N1
Li, K1
Chen, J1
Qiu, L1
Zhang, J1
Shi, HL2
Wu, XJ2
Liu, Y1
Xie, JQ1
Zhang, XZ1
Wang, L1
Liu, DW1
Tang, GY1
Zhang, HY1
Yi, T1
Zhuang, L1
Song, G1
Zhang, B1
Li, G1
Hu, T1
Pandey, A1
Vishnoi, K1
Mahata, S1
Tripathi, SC1
Misra, SP1
Misra, V1
Mehrotra, R1
Dwivedi, M1
Bharti, AC1
You, HY1
Xie, XM1
Zhang, WJ1
Zhu, HL1
Jiang, FZ1
Li, HL1
Wu, H1
Zhang, BB1
Yang, S1
Cai, X1
Dong, J1
Chen, Z1
Wang, R1
Zhang, S1
Cao, H1
Lu, D1
Jin, T1
Nie, Y1
Hao, J1
Fan, D1
Lin, JP1
Yang, JS1
Lee, JH1
Hsieh, WT1
Chung, JG1
Lin, HL1
Liu, TY1
Wu, CW1
Chi, CW1
Iwasa, K1
Moriyasu, M1
Yamori, T1
Turuo, T1
Lee, DU1
Wiegrebe, W1
Wang, MX1
Huo, LM1
Yang, HC1
Gao, YJ1
E, Z1

Reviews

2 reviews available for berberine and Stomach Neoplasms

ArticleYear
Berberine for gastric cancer prevention and treatment: Multi-step actions on the Correa's cascade underlie its therapeutic effects.
    Pharmacological research, 2022, Volume: 184

    Topics: Anti-Bacterial Agents; Berberine; Carcinogenesis; Cytokines; Gastritis; Gastritis, Atrophic; Helicob

2022
Phytochemicals and mitochondria: Therapeutic allies against gastric cancer.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 110

    Topics: Apoptosis; Berberine; Cell Line, Tumor; Humans; Mitochondria; Phytochemicals; Reactive Oxygen Specie

2023

Other Studies

15 other studies available for berberine and Stomach Neoplasms

ArticleYear
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
    Life sciences, 2022, Feb-01, Volume: 290

    Topics: Animals; Apoptosis; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; China; Gene Expr

2022
Combination of berberine and low glucose inhibits gastric cancer through the PP2A/GSK3β/MCL-1 signaling pathway.
    European journal of pharmacology, 2022, May-05, Volume: 922

    Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Glucose; Glycogen Synthase Kinase 3 beta; Huma

2022
Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: Animals; Antineoplastic Agents; Autophagy; Autophagy-Related Proteins; Berberine; Cell Line, Tumor;

2020
Integration of microRNA-mRNA profiles and pathway analysis of plant isoquinoline alkaloid berberine in SGC-7901 gastric cancers cells.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Down-

2018
Berberine counteracts enhanced IL-8 expression of AGS cells induced by evodiamine.
    Life sciences, 2013, Nov-19, Volume: 93, Issue:22

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Cell Adhesion; Cell Cycle; Cell Movement; Cell Prolife

2013
Synergistic inhibitory effect of berberine and d-limonene on human gastric carcinoma cell line MGC803.
    Journal of medicinal food, 2014, Volume: 17, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Caspase 3; Cell Cycle Checkpoints; Cell Lin

2014
Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells.
    Nutrition and cancer, 2015, Volume: 67, Issue:3

    Topics: Animals; Apoptosis; Berberine; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Mitochon

2015
Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil.
    Nutrition and cancer, 2015, Volume: 67, Issue:8

    Topics: Berberine; Cell Line, Tumor; Cell Survival; Curcumin; DNA; Drug Resistance, Neoplasm; Drug Synergism

2015
Berberine modulates cisplatin sensitivity of human gastric cancer cells by upregulation of miR-203.
    In vitro cellular & developmental biology. Animal, 2016, Volume: 52, Issue:8

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Berberine; Cell Line, Tumor; Cell Proliferation; Cisplatin

2016
MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo.
    Molecular medicine reports, 2016, Volume: 14, Issue:2

    Topics: Animals; Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Proliferation; Disease Models, Ani

2016
Berberine inhibits EGFR signaling and enhances the antitumor effects of EGFR inhibitors in gastric cancer.
    Oncotarget, 2016, Nov-15, Volume: 7, Issue:46

    Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell

2016
Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line.
    World journal of gastroenterology, 2006, Jan-07, Volume: 12, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Berberine; Calcium; Caspase 3; Caspase Inhibitors; Cell

2006
Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel.
    British journal of cancer, 1999, Volume: 81, Issue:3

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Carcinoma; C

1999
In vitro cytotoxicity of the protoberberine-type alkaloids.
    Journal of natural products, 2001, Volume: 64, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast

2001
An experimental study on the photodynamic activity of berberine in vitro on cancer cells.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1986, Volume: 6, Issue:2

    Topics: Berberine; Berberine Alkaloids; Cell Line; Humans; Microscopy, Fluorescence; Photochemotherapy; Stom

1986