berberine has been researched along with Reperfusion Injury in 25 studies
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our previous studies have shown that berberine can improve the nerve function deficits in ischemic stroke by inhibiting inflammation." | 8.31 | Astrocytes-derived exosomes pre-treated by berberine inhibit neuroinflammation after stroke via miR-182-5p/Rac1 pathway. ( Ding, W; Gu, Q; Liu, M; Sun, J; Zhu, J; Zou, J, 2023) |
| "In this study, hypoxia-reoxygenation (H/R)-treated L02 cells were pretreated with berberine to study the role and mechanism of berberine in resisting hepatic ischemia-reperfusion injury." | 8.31 | Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2. ( Li, C; Li, J; Liu, H; Ming, Y; Peng, B; Zhang, P; Zhu, Y, 2023) |
| "To investigate the effect of berberine on angiogenesis and signal transduction pathway of hypoxia-inducible growth factor-1α (HIF-1α) / vascular endothelial growth factor (VEGF) in rats with cerebral ischemia-reperfusion injury." | 7.88 | Effect of Berberine on Angiogenesis and HIF-1α / VEGF Signal Transduction Pathway in Rats with Cerebral Ischemia - Reperfusion Injury. ( Liu, H; Ma, C; Ren, X, 2018) |
| " This study aimed at investigating the effects of Berberine nanoparticles (BBR-NP) on the ischemia-reperfusion injury of renal tubular epithelial cells and underlying the mechanisms." | 7.85 | Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury. ( Hailun, L; Jing, W; Juxiang, Z; Lin, YT; Xie, D; Xu, Y; Yu, H; Zheng, DH, 2017) |
| " The present investigation was deliberated to scrutinize the renoprotective potential of berberine in animal model of renal ischemia reperfusion (RIR) induced dent via assessment of various biochemical and molecular biomarkers." | 7.81 | Renoprotective effect of berberine via intonation on apoptosis and mitochondrial-dependent pathway in renal ischemia reperfusion-induced mutilation. ( Bodhankar, SL; Kandhare, AD; Visnagri, A, 2015) |
| "Berberine is a natural medicine possessing multiple beneficial biological activities." | 6.61 | Berberine protects against ischemia-reperfusion injury: A review of evidence from animal models and clinical studies. ( Chen, N; Chen, SP; Liu, DQ; Sun, J; Tian, YK; Wang, XM; Ye, DW; Zhou, YQ, 2019) |
| "Berberine (BBR) is an anti-inflammatory alkaloid compound extracted from herbs." | 5.62 | Berberine exerts neuroprotective activities against cerebral ischemia/reperfusion injury through up-regulating PPAR-γ to suppress NF-κB-mediated pyroptosis. ( Li, Z; Lu, E; Sheng, Q; Zhao, Y, 2021) |
| "Berberine (BBR) has been demonstrated to protect against hepatic ischemia/reperfusion (I/R) injury." | 5.42 | Protective effect of Berberine pretreatment in hepatic ischemia/reperfusion injury of rat. ( Du, H; Sheng, M; Weng, Y; Xu, R; Yu, W; Zhou, Y, 2015) |
| "Berberine is a candidate clinical neuroprotective agent against ischemic stroke." | 5.38 | PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia-reperfusion. ( Chai, Y; Du, L; Hu, J; Kheir, MM; Lei, F; Li, H; Wan, H; Wang, Y; Xing, D; Yuan, Z, 2012) |
| "Our previous studies have shown that berberine can improve the nerve function deficits in ischemic stroke by inhibiting inflammation." | 4.31 | Astrocytes-derived exosomes pre-treated by berberine inhibit neuroinflammation after stroke via miR-182-5p/Rac1 pathway. ( Ding, W; Gu, Q; Liu, M; Sun, J; Zhu, J; Zou, J, 2023) |
| "In this study, hypoxia-reoxygenation (H/R)-treated L02 cells were pretreated with berberine to study the role and mechanism of berberine in resisting hepatic ischemia-reperfusion injury." | 4.31 | Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2. ( Li, C; Li, J; Liu, H; Ming, Y; Peng, B; Zhang, P; Zhu, Y, 2023) |
| "Berberine (BBR) has been demonstrated to protect against renal ischemia/reperfusion injury; however, the underlying molecular mechanism is largely unknown." | 3.88 | Berberine protects renal tubular cells against hypoxia/reoxygenation injury via the Sirt1/p53 pathway. ( Ding, Y; Du, H; Lin, Y; Lu, N; Sheng, M; Song, Y; Yu, W; Zhang, N, 2018) |
| "To investigate the effect of berberine on angiogenesis and signal transduction pathway of hypoxia-inducible growth factor-1α (HIF-1α) / vascular endothelial growth factor (VEGF) in rats with cerebral ischemia-reperfusion injury." | 3.88 | Effect of Berberine on Angiogenesis and HIF-1α / VEGF Signal Transduction Pathway in Rats with Cerebral Ischemia - Reperfusion Injury. ( Liu, H; Ma, C; Ren, X, 2018) |
| " This study aimed at investigating the effects of Berberine nanoparticles (BBR-NP) on the ischemia-reperfusion injury of renal tubular epithelial cells and underlying the mechanisms." | 3.85 | Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury. ( Hailun, L; Jing, W; Juxiang, Z; Lin, YT; Xie, D; Xu, Y; Yu, H; Zheng, DH, 2017) |
| " The present investigation was deliberated to scrutinize the renoprotective potential of berberine in animal model of renal ischemia reperfusion (RIR) induced dent via assessment of various biochemical and molecular biomarkers." | 3.81 | Renoprotective effect of berberine via intonation on apoptosis and mitochondrial-dependent pathway in renal ischemia reperfusion-induced mutilation. ( Bodhankar, SL; Kandhare, AD; Visnagri, A, 2015) |
| "To investigate the protective mechanism of geniposide, baicalin and berberine on hypoxia and reoxygenation injury in cultured rat cerebral microvascular endothelial cells." | 3.74 | [Effect of effective components of huanglian jiedu decoction on hypoxia, reoxygenation injury and the expression of VCAM in cultured rat cerebral microvascular endothelial cells]. ( Gao, YH; Niu, FL; Pang, H; Shan, ZS; Wang, SR; Yuan, ZZ; Zhu, LQ, 2008) |
| "Berberine is a natural medicine possessing multiple beneficial biological activities." | 2.61 | Berberine protects against ischemia-reperfusion injury: A review of evidence from animal models and clinical studies. ( Chen, N; Chen, SP; Liu, DQ; Sun, J; Tian, YK; Wang, XM; Ye, DW; Zhou, YQ, 2019) |
| "Berberine (BBR) is a known alkaloid that has verified its protective effects against ischemia/reperfusion (I/RN) lesion in multiple organs but its poor oral bioavailability limited its use." | 1.72 | Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy. ( Allam, MM; El-Haddad, AE; El-Mancy, SS; Elnagar, MR; Elnahas, OS; Fayez, SM; Gendy, AM; Khodir, AE; Mousa, MR, 2022) |
| "Berberine (BBR) is an anti-inflammatory alkaloid compound extracted from herbs." | 1.62 | Berberine exerts neuroprotective activities against cerebral ischemia/reperfusion injury through up-regulating PPAR-γ to suppress NF-κB-mediated pyroptosis. ( Li, Z; Lu, E; Sheng, Q; Zhao, Y, 2021) |
| "Berberine (BBR) is a pharmacological compound with a potential protective effect of the mitochondrial function in the context of I/R." | 1.48 | Addition of Berberine to Preservation Solution in an Animal Model of Ex Vivo Liver Transplant Preserves Mitochondrial Function and Bioenergetics from the Damage Induced by Ischemia/Reperfusion. ( Caetano Oliveira, R; Furtado, E; Marques Palmeira, C; Martins, RM; Pinto Rolo, A; Soeiro Teodoro, J; Tralhão, JG, 2018) |
| "Berberine (BBR) has been demonstrated to protect against hepatic ischemia/reperfusion (I/R) injury." | 1.42 | Protective effect of Berberine pretreatment in hepatic ischemia/reperfusion injury of rat. ( Du, H; Sheng, M; Weng, Y; Xu, R; Yu, W; Zhou, Y, 2015) |
| "Berberine (BBR) has been shown to attenuate the deleterious effects of ischemia/reperfusion (I/R) injury in the brain." | 1.39 | Berberine reduces rat intestinal tight junction injury induced by ischemia-reperfusion associated with the suppression of inducible nitric oxide synthesis. ( Gong, J; Gu, L; Li, J; Li, N; Li, Q; Yu, W; Zhu, W, 2013) |
| "Berberine (BBR) has been showed to attenuate ischemia/reperfusion injury by inhibiting oxidative stress." | 1.39 | Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways. ( Cui, K; Du, H; Ren, H; Sheng, M; Shi, L; Tong, J; Xu, R; Yu, J; Yu, W, 2013) |
| "Berberine is a candidate clinical neuroprotective agent against ischemic stroke." | 1.38 | PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia-reperfusion. ( Chai, Y; Du, L; Hu, J; Kheir, MM; Lei, F; Li, H; Wan, H; Wang, Y; Xing, D; Yuan, Z, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 17 (68.00) | 24.3611 |
| 2020's | 6 (24.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gendy, AM | 1 |
| Elnagar, MR | 1 |
| Allam, MM | 1 |
| Mousa, MR | 1 |
| Khodir, AE | 1 |
| El-Haddad, AE | 1 |
| Elnahas, OS | 1 |
| Fayez, SM | 1 |
| El-Mancy, SS | 1 |
| Zhao, Y | 2 |
| Li, Z | 1 |
| Lu, E | 1 |
| Sheng, Q | 1 |
| Ding, W | 1 |
| Gu, Q | 1 |
| Liu, M | 1 |
| Zou, J | 1 |
| Sun, J | 2 |
| Zhu, J | 1 |
| Zhu, Y | 1 |
| Li, J | 2 |
| Zhang, P | 1 |
| Peng, B | 1 |
| Li, C | 1 |
| Ming, Y | 1 |
| Liu, H | 2 |
| Liu, DQ | 1 |
| Chen, SP | 1 |
| Wang, XM | 1 |
| Chen, N | 1 |
| Zhou, YQ | 1 |
| Tian, YK | 1 |
| Ye, DW | 1 |
| Xie, P | 1 |
| Ren, ZK | 1 |
| Lv, J | 1 |
| Hu, YM | 1 |
| Guan, ZZ | 1 |
| Yu, WF | 1 |
| Xie, D | 1 |
| Xu, Y | 1 |
| Jing, W | 1 |
| Juxiang, Z | 1 |
| Hailun, L | 1 |
| Yu, H | 1 |
| Zheng, DH | 1 |
| Lin, YT | 1 |
| Martins, RM | 1 |
| Pinto Rolo, A | 1 |
| Soeiro Teodoro, J | 1 |
| Furtado, E | 1 |
| Caetano Oliveira, R | 1 |
| Tralhão, JG | 1 |
| Marques Palmeira, C | 1 |
| Yang, J | 1 |
| Yan, H | 1 |
| Li, S | 1 |
| Zhang, M | 1 |
| Lin, Y | 2 |
| Sheng, M | 4 |
| Ding, Y | 1 |
| Zhang, N | 1 |
| Song, Y | 1 |
| Du, H | 4 |
| Lu, N | 2 |
| Yu, W | 5 |
| Ren, X | 1 |
| Ma, C | 1 |
| Zhu, JR | 1 |
| Lu, HD | 1 |
| Guo, C | 1 |
| Fang, WR | 1 |
| Zhao, HD | 1 |
| Zhou, JS | 1 |
| Wang, F | 1 |
| Zhao, YL | 1 |
| Li, YM | 1 |
| Zhang, YD | 1 |
| Yang, CQ | 1 |
| Sun, JG | 1 |
| Kazaz, IO | 1 |
| Mentese, A | 1 |
| Demir, S | 1 |
| Kerimoglu, G | 1 |
| Colak, F | 1 |
| Bodur, A | 1 |
| Alver, A | 1 |
| Kutlu, O | 1 |
| Turedi, S | 1 |
| Chai, YS | 2 |
| Hu, J | 3 |
| Lei, F | 3 |
| Wang, YG | 2 |
| Yuan, ZY | 2 |
| Lu, X | 2 |
| Wang, XP | 1 |
| Du, F | 2 |
| Zhang, D | 1 |
| Xing, DM | 2 |
| Du, LJ | 2 |
| Gu, L | 1 |
| Li, N | 1 |
| Gong, J | 1 |
| Li, Q | 1 |
| Zhu, W | 1 |
| Jiang, JF | 1 |
| Visnagri, A | 1 |
| Kandhare, AD | 1 |
| Bodhankar, SL | 1 |
| Zhou, Y | 1 |
| Weng, Y | 2 |
| Xu, R | 3 |
| Huang, ZY | 1 |
| Pan, BB | 1 |
| Huang, CY | 1 |
| Ye, YL | 1 |
| Liu, DD | 1 |
| Yu, YP | 1 |
| Zhang, Q | 2 |
| Wang, J | 1 |
| Zhang, C | 1 |
| Liao, S | 1 |
| Li, P | 1 |
| Xu, D | 1 |
| Lv, Y | 1 |
| Yang, M | 1 |
| Kong, L | 1 |
| Yoo, KY | 1 |
| Hwang, IK | 1 |
| Kim, JD | 1 |
| Kang, IJ | 1 |
| Park, J | 1 |
| Yi, JS | 1 |
| Kim, JK | 1 |
| Bae, YS | 1 |
| Won, MH | 1 |
| Yuan, ZZ | 1 |
| Zhu, LQ | 1 |
| Pang, H | 1 |
| Shan, ZS | 1 |
| Wang, SR | 1 |
| Gao, YH | 1 |
| Niu, FL | 1 |
| Chai, Y | 1 |
| Wang, Y | 1 |
| Kheir, MM | 1 |
| Li, H | 1 |
| Yuan, Z | 1 |
| Wan, H | 1 |
| Xing, D | 1 |
| Du, L | 1 |
| Yu, J | 1 |
| Cui, K | 1 |
| Tong, J | 1 |
| Shi, L | 1 |
| Ren, H | 1 |
1 review available for berberine and Reperfusion Injury
| Article | Year |
|---|---|
Berberine protects against ischemia-reperfusion injury: A review of evidence from animal models and clinical studies.
Topics: Animals; Apoptosis; Autophagy; Berberine; Humans; Models, Animal; Protective Agents; Reperfusion Inj | 2019 |
24 other studies available for berberine and Reperfusion Injury
| Article | Year |
|---|---|
Berberine-loaded nanostructured lipid carriers mitigate warm hepatic ischemia/reperfusion-induced lesion through modulation of HMGB1/TLR4/NF-κB signaling and autophagy.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Autophagy; Berberine; Drug Carriers; HMGB1 Protein; Li | 2022 |
Berberine exerts neuroprotective activities against cerebral ischemia/reperfusion injury through up-regulating PPAR-γ to suppress NF-κB-mediated pyroptosis.
Topics: Animals; Berberine; Brain Ischemia; DNA-Binding Proteins; NF-kappa B; PPAR gamma; Pyroptosis; Rats; | 2021 |
Astrocytes-derived exosomes pre-treated by berberine inhibit neuroinflammation after stroke via miR-182-5p/Rac1 pathway.
Topics: Animals; Apoptosis; Astrocytes; Berberine; Exosomes; Glucose; Inflammation; Ischemic Stroke; Mice; M | 2023 |
Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2.
Topics: Berberine; Cytokines; Hepatocytes; Humans; Hypoxia; Reperfusion Injury | 2023 |
Berberine Ameliorates Oxygen-glucose Deprivation/Reperfusion-induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress and Autophagy in PC12 Cells.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Proteins; Berberine; Endoplasmic Reticulum Stress; | 2020 |
Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Berberine; Disease Models, Animal; Epithelial Cells; Kidney Function Tests; Kidn | 2017 |
Addition of Berberine to Preservation Solution in an Animal Model of Ex Vivo Liver Transplant Preserves Mitochondrial Function and Bioenergetics from the Damage Induced by Ischemia/Reperfusion.
Topics: Animals; Apoptosis; Berberine; Cold Ischemia; Disease Models, Animal; Humans; Liver; Liver Transplan | 2018 |
Berberine Ameliorates MCAO Induced Cerebral Ischemia/Reperfusion Injury via Activation of the BDNF-TrkB-PI3K/Akt Signaling Pathway.
Topics: Animals; Apoptosis; Berberine; Brain Ischemia; Brain-Derived Neurotrophic Factor; Infarction, Middle | 2018 |
Berberine protects renal tubular cells against hypoxia/reoxygenation injury via the Sirt1/p53 pathway.
Topics: Apoptosis; Berberine; Cell Hypoxia; Humans; Protective Agents; Reperfusion Injury; Sirtuin 1; Transf | 2018 |
Effect of Berberine on Angiogenesis and HIF-1α / VEGF Signal Transduction Pathway in Rats with Cerebral Ischemia - Reperfusion Injury.
Topics: Animals; Berberine; Brain Ischemia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Random Allocati | 2018 |
Berberine attenuates ischemia-reperfusion injury through inhibiting HMGB1 release and NF-κB nuclear translocation.
Topics: Animals; Berberine; Brain; Brain Edema; Down-Regulation; Glycyrrhizic Acid; HMGB1 Protein; Infarctio | 2018 |
Berberine inhibits the ischemia-reperfusion induced testicular injury through decreasing oxidative stress.
Topics: Animals; Antioxidants; Berberine; Disease Models, Animal; Humans; Male; Malondialdehyde; Oxidative S | 2020 |
Effect of berberine on cell cycle arrest and cell survival during cerebral ischemia and reperfusion and correlations with p53/cyclin D1 and PI3K/Akt.
Topics: Animals; Berberine; Brain Ischemia; Cell Cycle Checkpoints; Cell Survival; Cells, Cultured; Cyclin D | 2013 |
Berberine reduces rat intestinal tight junction injury induced by ischemia-reperfusion associated with the suppression of inducible nitric oxide synthesis.
Topics: Animals; Berberine; Disease Models, Animal; Intestinal Diseases; Intestinal Mucosa; Male; Membrane M | 2013 |
Inhibition of retinoblastoma mRNA degradation through Poly (A) involved in the neuroprotective effect of berberine against cerebral ischemia.
Topics: Animals; Apoptosis; Berberine; Brain Ischemia; Cell Cycle Checkpoints; Cell Survival; Hippocampus; M | 2014 |
Renoprotective effect of berberine via intonation on apoptosis and mitochondrial-dependent pathway in renal ischemia reperfusion-induced mutilation.
Topics: Acute Kidney Injury; Animals; Apoptosis; Berberine; Biomarkers; Caspase 3; Creatinine; Disease Model | 2015 |
Protective effect of Berberine pretreatment in hepatic ischemia/reperfusion injury of rat.
Topics: Animals; Apoptosis; Berberine; Caspase 3; In Situ Nick-End Labeling; Liver; Male; Oxidative Stress; | 2015 |
[Screening of Active Fractions from Huanglian Jiedu Decoction against Primary Neuron Injury after Oxygen-Glucose Deprivation].
Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal | 2015 |
The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model.
Topics: Animals; Berberine; Brain; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Flavonoids | 2016 |
Berberine protects against ischemia/reperfusion injury after orthotopic liver transplantation via activating Sirt1/FoxO3α induced autophagy.
Topics: Animals; Apoptosis; Autophagy; Berberine; Carbazoles; Forkhead Box Protein O3; Liver; Liver Transpla | 2017 |
Antiinflammatory effect of the ethanol extract of Berberis koreana in a gerbil model of cerebral ischemia/reperfusion.
Topics: Animals; Anti-Inflammatory Agents; Berberine; Berberis; Cyclooxygenase 2; Dinoprostone; Disease Mode | 2008 |
[Effect of effective components of huanglian jiedu decoction on hypoxia, reoxygenation injury and the expression of VCAM in cultured rat cerebral microvascular endothelial cells].
Topics: Animals; Berberine; Cell Hypoxia; Cells, Cultured; Cerebrum; Drugs, Chinese Herbal; Endothelium, Vas | 2008 |
PI3K p55γ promoter activity enhancement is involved in the anti-apoptotic effect of berberine against cerebral ischemia-reperfusion.
Topics: Animals; Apoptosis; Berberine; Brain Ischemia; Caspase 3; Enzyme Activation; Gene Expression Regulat | 2012 |
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways.
Topics: Apoptosis; Berberine; Blotting, Western; Caspase 3; Cell Line; Endoplasmic Reticulum; Enzyme Activat | 2013 |