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berberine and Renal Insufficiency

berberine has been researched along with Renal Insufficiency in 3 studies

Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the protective effects of berberine (BBR) against D-galactose (D-gal)-induced renal aging in rats, pointing to its ability to modulate phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt signalling, and to attenuate oxidative stress, inflammation and apoptosis."7.96Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism. ( El-Horany, HE; Gaballah, HH; Helal, DS, 2020)
"This study aimed to investigate the protective effects of berberine (BBR) against D-galactose (D-gal)-induced renal aging in rats, pointing to its ability to modulate phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt signalling, and to attenuate oxidative stress, inflammation and apoptosis."3.96Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism. ( El-Horany, HE; Gaballah, HH; Helal, DS, 2020)
" Moreover, in vitro assessment clearly showed BRB had a toxic effect on renal cell lines, while the primary metabolite, berberrubine-9-O-β-d-glucuronide (BRBG), did not show any obvious toxicity."1.43High fat diet aggravates the nephrotoxicity of berberrubine by influencing on its pharmacokinetic profile. ( Aa, J; Fei, F; Feng, S; Fu, F; Geng, J; Guo, J; He, J; Liao, X; Sun, R; Wang, G; Wang, H; Wang, J; Xie, Y; Yang, N; Zhao, Y; Zhen, L; Zhu, X, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Alorabi, M1
Cavalu, S1
Al-Kuraishy, HM1
Al-Gareeb, AI1
Mostafa-Hedeab, G1
Negm, WA1
Youssef, A1
El-Kadem, AH1
Saad, HM1
Batiha, GE1
El-Horany, HE1
Gaballah, HH1
Helal, DS1
Yang, N1
Sun, R1
Zhao, Y1
He, J1
Zhen, L1
Guo, J1
Geng, J1
Xie, Y1
Wang, J1
Feng, S1
Fei, F1
Liao, X1
Zhu, X1
Wang, H1
Fu, F1
Aa, J1
Wang, G1

Other Studies

3 other studies available for berberine and Renal Insufficiency

ArticleYear
Pentoxifylline and berberine mitigate diclofenac-induced acute nephrotoxicity in male rats via modulation of inflammation and oxidative stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 152

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Diclofenac; D

2022
Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism.
    Archives of physiology and biochemistry, 2020, Volume: 126, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aging; Animals; Anti-Inflammatory Agents; Antioxi

2020
High fat diet aggravates the nephrotoxicity of berberrubine by influencing on its pharmacokinetic profile.
    Environmental toxicology and pharmacology, 2016, Volume: 46

    Topics: Animals; Anti-Obesity Agents; Berberine; Cell Line; Cell Survival; Diet, High-Fat; Humans; Kidney; K

2016