Page last updated: 2024-10-23

berberine and Pregnancy

berberine has been researched along with Pregnancy in 19 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"To study whether a combination of berberine and letrozole results in higher live births than letrozole alone in infertile women with polycystic ovary syndrome (PCOS)."9.22Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome. ( Liang, RN; Liu, JP; Ma, HX; Ng, EH; Shao, XG; Wang, YY; Wu, XK; Xue, HY, 2016)
"Berberine and metformin treatments prior to IVF improved the pregnancy outcome by normalizing the clinical, endocrine and metabolic parameters in PCOS women."9.19The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. ( An, Y; Guan, Y; Liu, B; Lu, M; Sun, Z; Zhang, Y, 2014)
" In conclusion, the use of berberine for PCOS is safe and promising, even if more studies are needed to create a consensus about the dosage of berberine useful for long-term therapy."6.66Polycystic ovary syndrome management: a review of the possible amazing role of berberine. ( Faliva, MA; Gasparri, C; Infantino, V; Naso, M; Nichetti, M; Perna, S; Peroni, G; Petrangolini, G; Riva, A; Rondanelli, M; Spadaccini, D, 2020)
"To study whether a combination of berberine and letrozole results in higher live births than letrozole alone in infertile women with polycystic ovary syndrome (PCOS)."5.22Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome. ( Liang, RN; Liu, JP; Ma, HX; Ng, EH; Shao, XG; Wang, YY; Wu, XK; Xue, HY, 2016)
"Berberine and metformin treatments prior to IVF improved the pregnancy outcome by normalizing the clinical, endocrine and metabolic parameters in PCOS women."5.19The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. ( An, Y; Guan, Y; Liu, B; Lu, M; Sun, Z; Zhang, Y, 2014)
"A study was made of the effect of berberine, the major ingredient of the Chinese herb huanglian (coptis chinensis) reported to pose some risk for kernicterus among jaundiced newborn Chinese infants, on the protein binding of bilirubin, using the peroxidase kinetic method."3.68Displacement of bilirubin from albumin by berberine. ( Chan, E, 1993)
" In conclusion, the use of berberine for PCOS is safe and promising, even if more studies are needed to create a consensus about the dosage of berberine useful for long-term therapy."2.66Polycystic ovary syndrome management: a review of the possible amazing role of berberine. ( Faliva, MA; Gasparri, C; Infantino, V; Naso, M; Nichetti, M; Perna, S; Peroni, G; Petrangolini, G; Riva, A; Rondanelli, M; Spadaccini, D, 2020)
"Berberine (BBR) is an isoquinoline alkaloid extracted from Chinese herbs and exhibits glucose lowering properties."1.62Supplemental Berberine in a High-Fat Diet Reduces Adiposity and Cardiac Dysfunction in Offspring of Mouse Dams with Gestational Diabetes Mellitus. ( Chen, L; Cole, LK; Dolinsky, VW; Hatch, GM; Sparagna, GC; Vandel, M; Xiang, B; Zhang, M, 2021)
"Berberine (BBR) is an isoquinoline alkaloid from plants known to improve cardiac mitochondrial function in gestational diabetes mellitus (GDM) offspring but the mechanism is poorly understood."1.62Berberine elevates cardiolipin in heart of offspring from mouse dams with high fat diet-induced gestational diabetes mellitus. ( Cole, LK; Dolinsky, VW; Hatch, GM; Sparagna, GC; Vandel, M; Xiang, B, 2021)
"Berberine is an isoquinoline derivative alkaloid with anti-inflammatory activity."1.48The protective effect of berberine against lipopolysaccharide-induced abortion by modulation of inflammatory/immune responses. ( Barati, E; Fazel Nasab, N; Jalilvand, T; Mahdavi Siuki, M; Namdar Ahmadabad, H; Nezafat Firizi, M, 2018)
"Berberine was administered p."1.48Berberine Alleviates Tau Hyperphosphorylation and Axonopathy-Associated with Diabetic Encephalopathy via Restoring PI3K/Akt/GSK3β Pathway. ( Chen, J; Chen, Q; Feng, Z; Hang, W; He, B; Wang, S; Wang, X; Wu, N; Xia, L; Zhang, Q; Zhou, X, 2018)
" The rat maternal lowest observed adverse effect level (LOAEL), based on reduced maternal weight gain, was 7,250 ppm."1.33Developmental toxicity evaluation of berberine in rats and mice. ( George, JD; Jahnke, GD; Marr, MC; Myers, CB; Price, CJ, 2006)
"Pregnancy is associated with a suppression of maternal specific immune responses, which process underlies the protection of fetal tissues expressing paternally inherited alloantigens."1.31Enhanced tumor necrosis factor-alpha-specific and decreased interleukin-10-specific immune responses to LPS during the third trimester of pregnancy in mice. ( Haskó, G; Németh, ZH; Papp, Z; Selmeczy, ZS; Szelényi, J; Vizi, ES, 2001)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's1 (5.26)18.2507
2000's3 (15.79)29.6817
2010's8 (42.11)24.3611
2020's6 (31.58)2.80

Authors

AuthorsStudies
Miao, X1
Cui, W1
Ghavipanje, N1
Fathi Nasri, MH1
Farhangfar, SH1
Ghiasi, SE1
Vargas-Bello-Pérez, E1
Xia, Q1
Wang, W1
Liu, Z1
Xiao, J1
Qiao, C1
Zhao, Y1
Li, B1
Liu, Y1
Peng, Y1
Yang, X1
Shi, J1
Gao, X1
Wang, D1
Wang, Y1
Gong, W1
Lv, S1
Qu, H1
He, Y1
Rondanelli, M1
Infantino, V1
Riva, A1
Petrangolini, G1
Faliva, MA1
Peroni, G1
Naso, M1
Nichetti, M1
Spadaccini, D1
Gasparri, C1
Perna, S1
Cole, LK2
Zhang, M1
Chen, L1
Sparagna, GC2
Vandel, M2
Xiang, B2
Dolinsky, VW2
Hatch, GM2
Huang, CH1
Huang, ZW1
Ho, FM1
Chan, WH1
Mahdavi Siuki, M1
Fazel Nasab, N1
Barati, E1
Nezafat Firizi, M1
Jalilvand, T1
Namdar Ahmadabad, H1
Wang, S1
He, B1
Hang, W1
Wu, N1
Xia, L1
Wang, X1
Zhang, Q1
Zhou, X1
Feng, Z1
Chen, Q1
Chen, J1
Wang, JL1
Zhang, C2
Liu, B2
Huang, XM1
Dai, JG1
Tian, JH2
Gao, JM2
An, Y1
Sun, Z1
Zhang, Y1
Guan, Y1
Lu, M1
Shi, YR1
Liu, XR1
Cao, YC1
Zhen, D1
Jia, ZY1
Jiang, JQ1
Wu, XK1
Wang, YY1
Liu, JP1
Liang, RN1
Xue, HY1
Ma, HX1
Shao, XG1
Ng, EH1
Gold, AB1
Keller, AB1
Perry, DC1
Jahnke, GD1
Price, CJ1
Marr, MC1
Myers, CB1
George, JD1
Vaidya, AB1
Rajagopalan, TG1
Kale, AG1
Levine, RJ1
Chan, E1
Vizi, ES1
Szelényi, J1
Selmeczy, ZS1
Papp, Z1
Németh, ZH1
Haskó, G1

Reviews

2 reviews available for berberine and Pregnancy

ArticleYear
New insights into mechanisms of berberine in alleviating reproductive disorders of polycystic ovary syndrome: Anti-inflammatory properties.
    European journal of pharmacology, 2023, Jan-15, Volume: 939

    Topics: Anti-Inflammatory Agents; Berberine; Female; Humans; Polycystic Ovary Syndrome; Pregnancy; Pregnancy

2023
Polycystic ovary syndrome management: a review of the possible amazing role of berberine.
    Archives of gynecology and obstetrics, 2020, Volume: 301, Issue:1

    Topics: Adult; Berberine; Female; Humans; Polycystic Ovary Syndrome; Pregnancy

2020

Trials

3 trials available for berberine and Pregnancy

ArticleYear
Berberine supplementation modulates the somatotropic axis and ameliorates glucose tolerance in dairy goats during late gestation and early lactation.
    BMC veterinary research, 2022, Sep-24, Volume: 18, Issue:1

    Topics: Animals; Berberine; Blood Glucose; Diet; Dietary Supplements; Female; Glucagon; Glucose; Goats; Hydr

2022
The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment.
    Clinical endocrinology, 2014, Volume: 80, Issue:3

    Topics: Adult; Berberine; Female; Fertilization in Vitro; Humans; Hypoglycemic Agents; Infertility, Female;

2014
Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome.
    Fertility and sterility, 2016, Sep-01, Volume: 106, Issue:3

    Topics: Administration, Oral; Adult; Berberine; China; Double-Blind Method; Drug Administration Schedule; Dr

2016

Other Studies

14 other studies available for berberine and Pregnancy

ArticleYear
Berberine alleviates LPS-induced apoptosis, oxidation, and skewed lineages during mouse preimplantation development†.
    Biology of reproduction, 2022, 04-26, Volume: 106, Issue:4

    Topics: Animals; Apoptosis; Berberine; Cell Lineage; Female; Humans; Lipopolysaccharides; Mammals; Mice; Pol

2022
Berberine improves insulin resistance in adipocyte models by regulating the methylation of hypoxia-inducible factor-3α.
    Bioscience reports, 2019, 10-30, Volume: 39, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; Adult; Animals; Apoptosis Regulatory Proteins; Berberine; Diabetes, Gestat

2019
Supplemental Berberine in a High-Fat Diet Reduces Adiposity and Cardiac Dysfunction in Offspring of Mouse Dams with Gestational Diabetes Mellitus.
    The Journal of nutrition, 2021, 04-08, Volume: 151, Issue:4

    Topics: Adiposity; Animals; Berberine; Body Weight; Diabetes, Gestational; Diet, High-Fat; Dietary Supplemen

2021
Berberine elevates cardiolipin in heart of offspring from mouse dams with high fat diet-induced gestational diabetes mellitus.
    Scientific reports, 2021, 08-04, Volume: 11, Issue:1

    Topics: Acyltransferases; Animals; Berberine; Cardiolipins; Diabetes, Gestational; Diet, High-Fat; Electron

2021
Berberine impairs embryonic development in vitro and in vivo through oxidative stress-mediated apoptotic processes.
    Environmental toxicology, 2018, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; Berberine; Blastocyst; Cell Count; Embryo Implantation; Embryonic Development; F

2018
The protective effect of berberine against lipopolysaccharide-induced abortion by modulation of inflammatory/immune responses.
    Immunopharmacology and immunotoxicology, 2018, Volume: 40, Issue:4

    Topics: Abortion, Septic; Animals; Berberine; Female; Inflammation; Lipopolysaccharides; Male; Mice; Mice, I

2018
Berberine Alleviates Tau Hyperphosphorylation and Axonopathy-Associated with Diabetic Encephalopathy via Restoring PI3K/Akt/GSK3β Pathway.
    Journal of Alzheimer's disease : JAD, 2018, Volume: 65, Issue:4

    Topics: Animals; Axons; Berberine; Cells, Cultured; Chromones; Diabetes Mellitus, Type 2; Diabetic Nephropat

2018
Function of berberine on porcine in vitro fertilization embryo development and differential expression analysis of microRNAs.
    Reproduction in domestic animals = Zuchthygiene, 2019, Volume: 54, Issue:3

    Topics: Animals; Berberine; Blastocyst; Embryonic Development; Female; Fertilization in Vitro; Gene Expressi

2019
The Anti-Apoptotic Role of Berberine in Preimplantation Embryo In Vitro Development through Regulation of miRNA-21.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Apoptosis; Berberine; Blastocyst; Cell Count; Embryonic Development; Female; Gene Expressio

2015
Prenatal exposure of rats to nicotine causes persistent alterations of nicotinic cholinergic receptors.
    Brain research, 2009, Jan-23, Volume: 1250

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Berberine; Brain; Cerebral Cortex; Corpus Striatum;

2009
Developmental toxicity evaluation of berberine in rats and mice.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2006, Volume: 77, Issue:3

    Topics: Animals; Animals, Outbred Strains; Berberine; Embryonic Development; Feeding Behavior; Female; Fetal

2006
Inhibition of human pregnancy plasma diamine oxidase with alkaloids of Argemone mexicana--berberine and sanguinarine.
    Journal of postgraduate medicine, 1980, Volume: 26, Issue:1

    Topics: Alkaloids; Amine Oxidase (Copper-Containing); Benzophenanthridines; Berberine; Berberine Alkaloids;

1980
Displacement of bilirubin from albumin by berberine.
    Biology of the neonate, 1993, Volume: 63, Issue:4

    Topics: Animals; Berberine; Bilirubin; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; In

1993
Enhanced tumor necrosis factor-alpha-specific and decreased interleukin-10-specific immune responses to LPS during the third trimester of pregnancy in mice.
    The Journal of endocrinology, 2001, Volume: 171, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Berberine; Female; Gestational A

2001