Page last updated: 2024-10-23

berberine and Ovarian Neoplasms

berberine has been researched along with Ovarian Neoplasms in 11 studies

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study is to analyze the impact of berberine on the two human epithelial ovarian carcinoma cell lines OVCAR-3 and SKOV-3 in relation to the potential usefulness of berberine in the treatment of epithelial ovarian cancer."3.78Berberine-induced growth inhibition of epithelial ovarian carcinoma cell lines. ( Bae, J; Kim, JB; Lee, SJ; Park, KS, 2012)
"Berberine is an effective component extracted from the rhizomes of coptis chinensis and phellodendron chinensis."1.62Berberine inhibited metastasis through miR-145/MMP16 axis in vitro. ( Jiang, Y; Li, J; Pei, M; Wu, L; Zhang, S, 2021)
"Berberine is an extract of a traditional Chinese herbal medicine and has been shown to inhibit the proliferation and induce apoptosis in a wide variety of tumour cells."1.42Berberine exhibits antitumor effects in human ovarian cancer cells. ( Jin, P; Li, N; Zhang, C, 2015)
"Berberine could inhibit miR-21 expression and function in ovarian cancer, as shown by an enhancement of its target PDCD4, an important tumor suppressor in ovarian cancer."1.39Berberine sensitizes ovarian cancer cells to cisplatin through miR-21/PDCD4 axis. ( Fang, Y; Li, H; Liu, S; Shen, H; Xu, W, 2013)
"Berberine is a natural isoquinoline alkaloid with significant antitumor activity against many types of cancer cells, including ovarian tumors."1.39Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells. ( Costi, MP; Ferrari, S; Frassineti, C; Ligabue, A; Lombardi, P; Marverti, G; Monti, MG, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Chuang, TC1
Wu, K1
Lin, YY1
Kuo, HP1
Kao, MC1
Wang, V1
Hsu, SC1
Lee, SL1
Li, J2
Zhang, S1
Wu, L1
Pei, M1
Jiang, Y1
Zhao, Y2
Yang, X1
Zhao, J1
Gao, M1
Zhang, M1
Shi, T1
Zhang, F2
Zheng, X2
Pan, Y2
Shao, D2
He, K2
Chen, L2
Hou, D1
Xu, G1
Zhang, C2
Li, B1
Qin, J1
Hao, X1
Liu, Q1
Zhang, X1
Liu, J2
Wei, J1
Gong, Y1
Liu, Z1
Shao, C1
Cui, L1
Zhang, H1
Liu, L1
Fan, J1
Ai, G1
Luo, N1
Li, C1
Cheng, Z1
Liu, S1
Fang, Y1
Shen, H1
Xu, W1
Li, H1
Marverti, G1
Ligabue, A1
Lombardi, P1
Ferrari, S1
Monti, MG1
Frassineti, C1
Costi, MP1
Jin, P1
Li, N1
Park, KS1
Kim, JB1
Lee, SJ1
Bae, J1
Iwasa, K1
Moriyasu, M1
Yamori, T1
Turuo, T1
Lee, DU1
Wiegrebe, W1

Other Studies

11 other studies available for berberine and Ovarian Neoplasms

ArticleYear
Dual down-regulation of EGFR and ErbB2 by berberine contributes to suppression of migration and invasion of human ovarian cancer cells.
    Environmental toxicology, 2021, Volume: 36, Issue:5

    Topics: Berberine; Cell Line, Tumor; Down-Regulation; ErbB Receptors; Female; Humans; Ovarian Neoplasms; Pho

2021
Berberine inhibited metastasis through miR-145/MMP16 axis in vitro.
    Journal of ovarian research, 2021, Jan-06, Volume: 14, Issue:1

    Topics: Berberine; Cell Line, Tumor; Female; Humans; Matrix Metalloproteinase 16; MicroRNAs; Neoplasm Metast

2021
Berberine inhibits chemotherapy-exacerbated ovarian cancer stem cell-like characteristics and metastasis through GLI1.
    European journal of pharmacology, 2021, Mar-15, Volume: 895

    Topics: Antineoplastic Agents; Berberine; Carboplatin; Cell Line, Tumor; Cell Movement; Coculture Techniques

2021
Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition.
    Cell death & disease, 2017, 10-05, Volume: 8, Issue:10

    Topics: Apoptosis; Berberine; Cell Line, Tumor; DNA Damage; Female; Humans; Ovarian Neoplasms; Oxidative Str

2017
Berberine inhibits the chemotherapy-induced repopulation by suppressing the arachidonic acid metabolic pathway and phosphorylation of FAK in ovarian cancer.
    Cell proliferation, 2017, Volume: 50, Issue:6

    Topics: Apoptosis; Arachidonic Acid; Berberine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Prolif

2017
Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells.
    Biological research, 2019, Jul-18, Volume: 52, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Berberine; Caspase

2019
Berberine sensitizes ovarian cancer cells to cisplatin through miR-21/PDCD4 axis.
    Acta biochimica et biophysica Sinica, 2013, Volume: 45, Issue:9

    Topics: 3' Untranslated Regions; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Berberine;

2013
Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells.
    International journal of oncology, 2013, Volume: 43, Issue:4

    Topics: Acetyltransferases; Berberine; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neo

2013
Berberine exhibits antitumor effects in human ovarian cancer cells.
    Anti-cancer agents in medicinal chemistry, 2015, Volume: 15, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Berberine; Cell Line, Tumor;

2015
Berberine-induced growth inhibition of epithelial ovarian carcinoma cell lines.
    The journal of obstetrics and gynaecology research, 2012, Volume: 38, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Carcinoma, Ovarian Epithelial; Cell Cycle;

2012
In vitro cytotoxicity of the protoberberine-type alkaloids.
    Journal of natural products, 2001, Volume: 64, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast

2001