berberine has been researched along with Osteosarcoma in 8 studies
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cells from the human osteosarcoma cell line MG-63 were exposed to γ-ray irradiation (0, 2, 4, 6, and 8 Gy) and berberine (20 μM)." | 7.96 | Berberine enhances the radiosensitivity of osteosarcoma by targeting Rad51 and epithelial-mesenchymal transition. ( Du, G; Wang, D; Wang, J; Zhang, KF; Zhao, J, 2020) |
| "Berberine (BBR) has been reported to have potent anticancer activity and can increase the anticancer effects of chemotherapy drugs." | 5.62 | Berberine and Cisplatin Exhibit Synergistic Anticancer Effects on Osteosarcoma MG-63 Cells by Inhibiting the MAPK Pathway. ( Gao, X; Hong, T; Wang, Y; Zhang, C; Zhang, J; Zhang, P, 2021) |
| "Osteosarcoma is the most frequently occurring cancer in children as well as young adolescents and the metastatic forms worsen this condition to a further great extent." | 5.56 | Berberine reverses epithelial-mesenchymal transition and modulates histone methylation in osteosarcoma cells. ( Mishra, R; Nathani, S; Roy, P; Sircar, D; Varshney, R, 2020) |
| "Berberine is an isoquinoline alkaloid extracted from the dry root of Coptidis Rhizoma, which has been found to exhibit significant anticancer effects on a wide spectrum of carcinomas including osteosarcoma." | 5.46 | Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis. ( Cao, B; Jin, H; Jin, X; Wang, W, 2017) |
| "Cells from the human osteosarcoma cell line MG-63 were exposed to γ-ray irradiation (0, 2, 4, 6, and 8 Gy) and berberine (20 μM)." | 3.96 | Berberine enhances the radiosensitivity of osteosarcoma by targeting Rad51 and epithelial-mesenchymal transition. ( Du, G; Wang, D; Wang, J; Zhang, KF; Zhao, J, 2020) |
| "Berberine (BBR) has been reported to have potent anticancer activity and can increase the anticancer effects of chemotherapy drugs." | 1.62 | Berberine and Cisplatin Exhibit Synergistic Anticancer Effects on Osteosarcoma MG-63 Cells by Inhibiting the MAPK Pathway. ( Gao, X; Hong, T; Wang, Y; Zhang, C; Zhang, J; Zhang, P, 2021) |
| "Osteosarcoma is the most frequently occurring cancer in children as well as young adolescents and the metastatic forms worsen this condition to a further great extent." | 1.56 | Berberine reverses epithelial-mesenchymal transition and modulates histone methylation in osteosarcoma cells. ( Mishra, R; Nathani, S; Roy, P; Sircar, D; Varshney, R, 2020) |
| "Berberine is an isoquinoline alkaloid extracted from the dry root of Coptidis Rhizoma, which has been found to exhibit significant anticancer effects on a wide spectrum of carcinomas including osteosarcoma." | 1.46 | Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis. ( Cao, B; Jin, H; Jin, X; Wang, W, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, D | 1 |
| Zhang, KF | 1 |
| Du, G | 1 |
| Wang, J | 1 |
| Zhao, J | 1 |
| Mishra, R | 1 |
| Nathani, S | 1 |
| Varshney, R | 1 |
| Sircar, D | 1 |
| Roy, P | 1 |
| Gao, X | 1 |
| Zhang, C | 1 |
| Wang, Y | 1 |
| Zhang, P | 1 |
| Zhang, J | 1 |
| Hong, T | 1 |
| Hsu, HK | 1 |
| Hsu, KH | 1 |
| Cheng, YM | 1 |
| Suen, HY | 1 |
| Peng, SF | 1 |
| Yu, D | 1 |
| Fu, S | 1 |
| Cao, Z | 1 |
| Bao, M | 1 |
| Zhang, G | 1 |
| Pan, Y | 1 |
| Liu, W | 1 |
| Zhou, Q | 1 |
| Zhu, Y | 1 |
| Ma, N | 1 |
| Li, HX | 1 |
| Tian, L | 1 |
| Ba, YF | 1 |
| Hao, B | 1 |
| Jin, H | 1 |
| Jin, X | 1 |
| Cao, B | 1 |
| Wang, W | 1 |
| Liu, Z | 1 |
| Liu, Q | 1 |
| Xu, B | 1 |
| Wu, J | 1 |
| Guo, C | 1 |
| Zhu, F | 1 |
| Yang, Q | 1 |
| Gao, G | 1 |
| Gong, Y | 1 |
| Shao, C | 1 |
8 other studies available for berberine and Osteosarcoma
| Article | Year |
|---|---|
Berberine enhances the radiosensitivity of osteosarcoma by targeting Rad51 and epithelial-mesenchymal transition.
Topics: Berberine; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Epithelial-Mesen | 2020 |
Berberine reverses epithelial-mesenchymal transition and modulates histone methylation in osteosarcoma cells.
Topics: Actin Cytoskeleton; Berberine; beta Catenin; Cadherins; Cell Line, Tumor; Cell Movement; Cell Prolif | 2020 |
Berberine and Cisplatin Exhibit Synergistic Anticancer Effects on Osteosarcoma MG-63 Cells by Inhibiting the MAPK Pathway.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Berberine; Ce | 2021 |
Development and In Vitro Evaluation of Linear PEI-Shelled Heparin/Berberine Nanoparticles in Human Osteosarcoma U-2 OS Cells.
Topics: Antineoplastic Agents; Berberine; Bone Neoplasms; Drug Carriers; Heparin; Humans; Nanoparticles; Ost | 2018 |
Unraveling the novel anti-osteosarcoma function of coptisine and its mechanisms.
Topics: Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; Berberine; Bone Neoplasms; Cadherins; Cell | 2014 |
Berberine induces apoptosis and DNA damage in MG‑63 human osteosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Bone Neoplasms; Cell Line, Tumor; Coptis chinensis; DNA | 2014 |
Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis.
Topics: Animals; Apoptosis; Berberine; Blotting, Western; Bone Neoplasms; Caspase 1; Cell Proliferation; Dow | 2017 |
Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage.
Topics: Apoptosis; Berberine; Cell Cycle; Cell Proliferation; DNA Damage; G1 Phase; G2 Phase; Gene Expressio | 2009 |