berberine has been researched along with Neoplasms in 56 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine is a bioactive alkaloid found in herbal plants (e." | 6.82 | Effects of Berberine on Leukemia with a Focus on Its Molecular Targets. ( Asemi, Z; Dana, PM; Hallajzadeh, J; Mansournia, MA; Mazandaranian, MR; Yousefi, B, 2022) |
| " Various in vitro and in vivo studies have reported the anti-inflammatory role of berberine (BRB), an organic heteropentacyclic phytochemical and natural isoquinoline, in inhibiting NLRP3 inflammasome-dependent inflammation against many disorders." | 5.12 | Inhibitory Role of Berberine, an Isoquinoline Alkaloid, on NLRP3 Inflammasome Activation for the Treatment of Inflammatory Diseases. ( Abrahamse, H; George, BP; Sarbadhikary, P, 2021) |
| "Berberine is a bioactive alkaloid found in herbal plants (e." | 2.82 | Effects of Berberine on Leukemia with a Focus on Its Molecular Targets. ( Asemi, Z; Dana, PM; Hallajzadeh, J; Mansournia, MA; Mazandaranian, MR; Yousefi, B, 2022) |
| "Berberine exhibits an anticancer role through scavenging free radicals, induction of apoptosis, cell cycle arrest, inhibition of angiogenesis, inflammation, PI3K/AKT/mammalian target of rapamycin (mTOR), Wnt/β-catenin, and the MAPK/ERK signaling pathway." | 2.82 | Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways. ( Almatroodi, SA; Alsahli, MA; Rahmani, AH, 2022) |
| "Cancer is the second leading cause of death in the world." | 2.72 | Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives. ( Akter, R; Bibi, P; Hassan, SSU; Mubin, S; Najda, A; Rahman, MH; Saeeda, S; Shah, M; Wesołowska, S, 2021) |
| "BBR prevents cancer cell proliferation by inducing apoptosis and controlling the cell cycle as well as autophagy." | 2.72 | Berberine as a Potential Anticancer Agent: A Comprehensive Review. ( Abu-Izneid, T; Alhumaydhi, FA; Aljohani, ASM; Emran, TB; Gondal, TA; Imran, M; Jeandet, P; Khalil, AA; Khan, I; Khan, Z; Mitra, S; Rahman, MM; Rauf, A; Shah, ZA, 2021) |
| "BBR effectively sensitizes refractory cancers to chemotherapy and radiotherapy by ameliorating the diverse events underlying therapy resistance." | 2.72 | Berberine-A potent chemosensitizer and chemoprotector to conventional cancer therapies. ( Devarajan, N; Ganesan, SK; Jayaraman, S; Mahendra, J; Palaniappan, H; Rajagopal, P; Venkatratnam, P, 2021) |
| "Berberine (BBR) is a nature-driven phytochemical component originated from different plant groups such as Berberis vulgaris, Berberis aquifolium, and Berberis aristata." | 2.66 | Berberine: A novel therapeutic strategy for cancer. ( Aghebati-Maleki, L; Asenjan, KS; Gholipour, E; Hojjat-Farsangi, M; Motavalli, R; Samadi, P; Sarvarian, P; Yousefi, M, 2020) |
| "The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant cancers make an urgent need to develop more effective anti-cancer candidates." | 2.61 | Quinolone hybrids and their anti-cancer activities: An overview. ( Gao, F; Wang, T; Xiao, J; Zhang, X, 2019) |
| "00001) in a linear The dose-response relationship (Pearson r = - 0." | 2.61 | Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis. ( Long, Y; Ni, L; Tao, J; Wu, R; Xu, J; Yu, N; Yuan, X; Zhang, Y, 2019) |
| "Berberine (BBR) is an isoquinoline alkaloid found in different plant families such as Berberidaceae, Ranunculaceae, and Papaveraceae." | 2.55 | Regulatory effects of berberine on microRNome in Cancer and other conditions. ( Ayati, SH; Cicero, AFG; Fazeli, B; Momtazi-Borojeni, AA; Pirro, M; Sahebkar, A, 2017) |
| " It is necessary to improve the oral bioavailability of BBR before it can be used in many clinical applications." | 2.53 | Research progress on berberine with a special focus on its oral bioavailability. ( Liu, CS; Long, XY; Zhang, YF; Zheng, YR, 2016) |
| "Unspecified cancer type and staging, fluctuated dose information and variants of targets across studies of berberine/ Coptidis Rhizoma impede their clinical use for cancer treatment." | 2.52 | Berberine and Coptidis Rhizoma as potential anticancer agents: Recent updates and future perspectives. ( Feng, Y; Li, L; Tan, HY; Wang, N; Yuen, MF, 2015) |
| "Cancer is a multifactorial and multistep disease, so the treatment effect of combination formulas and prescriptions in TCMs involving multi-targets and multi-signal pathways on tumor may be superior than that of agents targeting a single molecular target alone." | 2.50 | Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development. ( Bai, XY; Wang, CH; Wang, CY, 2014) |
| "Breast cancer is the most common cancer among women worldwide and novel therapeutic agents are needed to treat this disease." | 2.50 | Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. ( Ismail, P; Jabbarzadeh Kaboli, P; Ling, KH; Rahmat, A, 2014) |
| "The National Cancer Institute 60 (NCI60), which consists of 60 cell lines from various human cancer types, remains the most powerful human cancer cell line panel for high throughput screening of anticancer drugs." | 2.48 | JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs. ( Kong, D; Yamori, T, 2012) |
| " The present review supplies evidence that berberine is a safe anti-cancer agent, exerting several effects on mitochondria, including inhibition of mitochondrial Complex I and interaction with the adenine nucleotide translocator which can explain several of the described effects on tumor cells." | 2.47 | Berberine as a promising safe anti-cancer agent - is there a role for mitochondria? ( Barbosa, IA; Burgeiro, A; Diogo, CV; Machado, NG; Oliveira, PJ; Serafim, TL, 2011) |
| "Berberine hydrochloride is a conventional component in Chinese medicine, and is characterized by a diversity of pharmacological effects." | 2.47 | Berberine hydrochloride: anticancer activity and nanoparticulate delivery system. ( Chen, M; Li, Y; Tan, W; Wang, Y, 2011) |
| "Berberine is an isoquinoline alkaloid isolated from Chinese herbs such as Coptidis Rhizome." | 2.47 | Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine. ( Chen, WM; Huang, ZJ; Lan, P; Sun, PH; Zeng, Y, 2011) |
| " Here, a 3D tumor-immune cell coculture spheroid model was developed to mimic tumor-immune interactions, combined with mass spectrometry imaging-based spatially resolved metabolomics to visualize tumor immunometabolic alterations during immune response." | 1.91 | Spatially Resolved Metabolomics Combined with the 3D Tumor-Immune Cell Coculture Spheroid Highlights Metabolic Alterations during Antitumor Immune Response. ( Chen, P; Chen, X; Han, Y; Sun, C; Wang, L; Wang, X; Zhang, M; Zhao, Y; Zheng, Y; Zhu, Z, 2023) |
| "Berberine (BBR) is a commonly used anti-intestinal inflammation drug, and its anti-cancer activity has been found recently." | 1.91 | Identification of FtfL as a novel target of berberine in intestinal bacteria. ( Fang, C; Fang, J; Gu, Y; Jiang, W; Li, J; Liu, Y; Yan, J; Yang, G; Yang, P; Zhang, L; Zhang, Y, 2023) |
| "Its anticancer activity in vivo was demonstrated by the mouse xenograft model." | 1.72 | Improvement of anticancer effect of berberine by salt formation modifications. ( Liao, Y; Liu, M; Liu, Z; Xu, F; Zeng, Y; Zhang, P; Zhou, Y, 2022) |
| "Berberine-LCNs were prepared by mixing berberine, monoolein and poloxamer 407 (P407) using ultrasonication method." | 1.62 | Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro. ( Chellappan, DK; Dua, K; Hansbro, PM; Malyla, V; Mehta, M; Oliver, BG; Paudel, KR, 2021) |
| "Berberine is an effective component of rhizoma coptidis, with a very good antitumor effect." | 1.62 | [Research progress in mechanism of berberine's antitumor action]. ( Chen, T; Gong, YY; Luo, MJ; Luo, S; Yang, XH; Zhang, LJ, 2021) |
| "Paclitaxel (PTX) is a broad-spectrum anticancer drug, but its therapeutic effect is highly limited due to the development of multidrug resistance." | 1.56 | Mitochondria-targeting nanomedicine self-assembled from GSH-responsive paclitaxel-ss-berberine conjugate for synergetic cancer treatment with enhanced cytotoxicity. ( Cheng, Y; Ji, Y, 2020) |
| "Berberine is an isoquinoline alkaloid extracted from the root, rhizome and stem bark of Coptidis Rhizoma." | 1.56 | Berberine inhibits cancer cells growth by suppressing fatty acid synthesis and biogenesis of extracellular vesicles. ( Gu, S; Huang, D; Li, Q; Liang, B; Ouyang, C; Song, X; Su, T; Xie, L; Xie, R; Xu, M; Xu, T, 2020) |
| "Lung cancer is the worldwide leading cause of cancer-related death." | 1.51 | 8-Cetylcoptisine, a new coptisine derivative, induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest in human A549 cells. ( Han, B; Jiang, P; Li, X; Liu, L; Liu, W; Ma, W; Wu, S; Xu, H; Ye, X; Zhang, J, 2019) |
| "Berberine (BBR) is an alkaloid that is widely distributed in different plant species." | 1.48 | Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment. ( Ismail, P; Jabbarzadeh Kaboli, P; Ling, KH, 2018) |
| "Berberine was found to interact with Lys395 of Smo receptor via hydrogen bonding and cation-π interactions." | 1.46 | Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs. ( Bazrafkan, M; Ismail, P; Kaboli, PJ; Ling, KH, 2017) |
| "Berberine (BBR) has shown promising antitumour effects in vitro." | 1.46 | Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes. ( Liu, Z; Wang, Q; Wang, X; Zheng, X, 2017) |
| "Cancer is one of the main causes of death for human beings." | 1.42 | [18F-Berberine Derivatives: a Potential Molecular Imaging Agent for Tumor Targeting by PET/CT Tumor]. ( Fan, C; Liang, M; Mei, X; Wu, X; Zhang, T, 2015) |
| "In a Panc 02 pancreatic cancer model in mice, lovastatin-berberine combination slightly, but significantly, slowed down tumor growth." | 1.37 | Antitumor effects of the combination of cholesterol reducing drugs. ( Bil, J; Golab, J; Issat, T; Jakobisiak, M; Nowis, D; Winiarska, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (3.57) | 29.6817 |
| 2010's | 31 (55.36) | 24.3611 |
| 2020's | 23 (41.07) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, D | 1 |
| Yamori, T | 1 |
| Mohd Siddique, MU | 1 |
| Barbhuiya, TK | 1 |
| Sinha, BN | 1 |
| Jayaprakash, V | 1 |
| Gao, F | 1 |
| Zhang, X | 2 |
| Wang, T | 1 |
| Xiao, J | 1 |
| Liu, Y | 4 |
| He, S | 1 |
| Chen, Y | 1 |
| Feng, F | 1 |
| Liu, W | 2 |
| Guo, Q | 1 |
| Zhao, L | 1 |
| Sun, H | 1 |
| Fu, DJ | 1 |
| Li, J | 2 |
| Yu, B | 1 |
| Mehta, M | 1 |
| Malyla, V | 1 |
| Paudel, KR | 1 |
| Chellappan, DK | 1 |
| Hansbro, PM | 1 |
| Oliver, BG | 1 |
| Dua, K | 1 |
| Akter, R | 1 |
| Najda, A | 1 |
| Rahman, MH | 1 |
| Shah, M | 1 |
| Wesołowska, S | 1 |
| Hassan, SSU | 1 |
| Mubin, S | 1 |
| Bibi, P | 1 |
| Saeeda, S | 1 |
| Sarbadhikary, P | 1 |
| George, BP | 1 |
| Abrahamse, H | 1 |
| Rauf, A | 1 |
| Abu-Izneid, T | 1 |
| Khalil, AA | 1 |
| Imran, M | 1 |
| Shah, ZA | 1 |
| Emran, TB | 1 |
| Mitra, S | 1 |
| Khan, Z | 1 |
| Alhumaydhi, FA | 1 |
| Aljohani, ASM | 1 |
| Khan, I | 1 |
| Rahman, MM | 1 |
| Jeandet, P | 1 |
| Gondal, TA | 1 |
| Mazandaranian, MR | 1 |
| Dana, PM | 1 |
| Asemi, Z | 1 |
| Hallajzadeh, J | 1 |
| Mansournia, MA | 1 |
| Yousefi, B | 1 |
| Xu, F | 1 |
| Liu, M | 1 |
| Liao, Y | 1 |
| Zhou, Y | 2 |
| Zhang, P | 1 |
| Zeng, Y | 2 |
| Liu, Z | 2 |
| Zhao, T | 1 |
| Zhang, Q | 1 |
| Cang, F | 1 |
| Wu, S | 2 |
| Jiang, Y | 1 |
| Zhao, Q | 1 |
| Qu, X | 1 |
| Jin, Y | 1 |
| Li, Y | 2 |
| Fu, Y | 1 |
| Almatroodi, SA | 1 |
| Alsahli, MA | 1 |
| Rahmani, AH | 1 |
| Zhu, C | 1 |
| Li, K | 1 |
| Peng, XX | 1 |
| Yao, TJ | 1 |
| Wang, ZY | 1 |
| Hu, P | 1 |
| Cai, D | 1 |
| Liu, HY | 1 |
| Devarajan, N | 2 |
| Nathan, J | 1 |
| Mathangi, R | 1 |
| Mahendra, J | 2 |
| Ganesan, SK | 2 |
| Zhong, X | 1 |
| Deng, H | 1 |
| Long, M | 1 |
| Yin, H | 1 |
| Zhong, Q | 1 |
| Zheng, S | 1 |
| Gong, T | 1 |
| He, L | 1 |
| Wang, G | 1 |
| Sun, Q | 1 |
| Chen, P | 1 |
| Han, Y | 1 |
| Wang, L | 1 |
| Zheng, Y | 1 |
| Zhu, Z | 1 |
| Zhao, Y | 1 |
| Zhang, M | 1 |
| Chen, X | 1 |
| Wang, X | 2 |
| Sun, C | 1 |
| Yan, J | 1 |
| Fang, C | 1 |
| Yang, G | 1 |
| Zhang, L | 1 |
| Yang, P | 1 |
| Fang, J | 1 |
| Gu, Y | 1 |
| Zhang, Y | 4 |
| Jiang, W | 1 |
| Wang, ZC | 1 |
| Wang, J | 1 |
| Chen, H | 1 |
| Tang, J | 1 |
| Bian, AW | 1 |
| Liu, T | 1 |
| Yu, LF | 1 |
| Yi, Z | 1 |
| Yang, F | 1 |
| Cheng, Y | 1 |
| Ji, Y | 1 |
| D'Arcy, MS | 1 |
| Gu, S | 1 |
| Song, X | 1 |
| Xie, R | 1 |
| Ouyang, C | 1 |
| Xie, L | 1 |
| Li, Q | 1 |
| Su, T | 1 |
| Xu, M | 1 |
| Xu, T | 1 |
| Huang, D | 1 |
| Liang, B | 1 |
| Samadi, P | 1 |
| Sarvarian, P | 1 |
| Gholipour, E | 1 |
| Asenjan, KS | 1 |
| Aghebati-Maleki, L | 1 |
| Motavalli, R | 1 |
| Hojjat-Farsangi, M | 1 |
| Yousefi, M | 1 |
| Jayaraman, S | 1 |
| Venkatratnam, P | 1 |
| Rajagopal, P | 1 |
| Palaniappan, H | 1 |
| Yang, XH | 1 |
| Zhang, LJ | 1 |
| Luo, MJ | 1 |
| Luo, S | 1 |
| Gong, YY | 1 |
| Chen, T | 1 |
| Šudomová, M | 1 |
| Berchová-Bímová, K | 1 |
| Marzocco, S | 1 |
| Liskova, A | 1 |
| Kubatka, P | 1 |
| Hassan, STS | 1 |
| McCubrey, JA | 2 |
| Lertpiriyapong, K | 2 |
| Steelman, LS | 2 |
| Abrams, SL | 2 |
| Cocco, L | 2 |
| Ratti, S | 2 |
| Martelli, AM | 2 |
| Candido, S | 2 |
| Libra, M | 2 |
| Montalto, G | 2 |
| Cervello, M | 2 |
| Gizak, A | 2 |
| Rakus, D | 2 |
| Ayati, SH | 1 |
| Fazeli, B | 1 |
| Momtazi-Borojeni, AA | 1 |
| Cicero, AFG | 1 |
| Pirro, M | 1 |
| Sahebkar, A | 1 |
| Kaboli, PJ | 1 |
| Bazrafkan, M | 1 |
| Ismail, P | 3 |
| Ling, KH | 3 |
| Murata, RM | 1 |
| Rosalen, PL | 1 |
| Lombardi, P | 3 |
| Jabbarzadeh Kaboli, P | 2 |
| Geng, C | 1 |
| Hidru, TH | 1 |
| Zhi, L | 1 |
| Tao, M | 1 |
| Zou, L | 2 |
| Chen, C | 1 |
| Li, H | 1 |
| Yahuafai, J | 1 |
| Asai, T | 1 |
| Oku, N | 1 |
| Siripong, P | 1 |
| Agnarelli, A | 1 |
| Natali, M | 1 |
| Garcia-Gil, M | 1 |
| Pesi, R | 1 |
| Tozzi, MG | 1 |
| Ippolito, C | 1 |
| Bernardini, N | 1 |
| Vignali, R | 1 |
| Batistoni, R | 1 |
| Bianucci, AM | 1 |
| Marracci, S | 1 |
| Han, B | 1 |
| Jiang, P | 1 |
| Xu, H | 1 |
| Zhang, J | 1 |
| Liu, L | 1 |
| Ma, W | 1 |
| Li, X | 1 |
| Ye, X | 1 |
| Xu, J | 1 |
| Long, Y | 1 |
| Ni, L | 1 |
| Yuan, X | 1 |
| Yu, N | 1 |
| Wu, R | 1 |
| Tao, J | 1 |
| Yao, J | 1 |
| Kong, W | 1 |
| Jiang, J | 1 |
| Pund, S | 1 |
| Borade, G | 1 |
| Rasve, G | 1 |
| Wang, CY | 1 |
| Bai, XY | 1 |
| Wang, CH | 1 |
| Rahmat, A | 1 |
| Ortiz, LM | 1 |
| Tillhon, M | 1 |
| Scovassi, AI | 1 |
| Mei, X | 1 |
| Wu, X | 1 |
| Zhang, T | 1 |
| Liang, M | 1 |
| Fan, C | 1 |
| Bao, J | 1 |
| Huang, B | 1 |
| Chen, S | 2 |
| Zhang, C | 1 |
| Chen, M | 2 |
| Wan, JB | 1 |
| Su, H | 1 |
| Wang, Y | 2 |
| He, C | 1 |
| Wang, N | 1 |
| Tan, HY | 1 |
| Li, L | 1 |
| Yuen, MF | 1 |
| Feng, Y | 1 |
| Liu, CS | 1 |
| Zheng, YR | 1 |
| Zhang, YF | 1 |
| Long, XY | 1 |
| Park, GB | 1 |
| Park, SH | 1 |
| Kim, D | 1 |
| Kim, YS | 1 |
| Yoon, SH | 1 |
| Hur, DY | 1 |
| Wang, Q | 1 |
| Zheng, X | 1 |
| Youns, M | 1 |
| Hoheisel, JD | 1 |
| Efferth, T | 1 |
| Diogo, CV | 1 |
| Machado, NG | 1 |
| Barbosa, IA | 1 |
| Serafim, TL | 1 |
| Burgeiro, A | 1 |
| Oliveira, PJ | 1 |
| Issat, T | 1 |
| Nowis, D | 1 |
| Bil, J | 1 |
| Winiarska, M | 1 |
| Jakobisiak, M | 1 |
| Golab, J | 1 |
| Tan, W | 1 |
| Bhowmik, D | 1 |
| Hossain, M | 1 |
| Buzzetti, F | 1 |
| D'Auria, R | 1 |
| Kumar, GS | 1 |
| Huang, ZJ | 1 |
| Lan, P | 1 |
| Sun, PH | 1 |
| Chen, WM | 1 |
| Xiao, N | 1 |
| Ma, Y | 1 |
| Qiu, J | 1 |
| Tan, JH | 1 |
| Ou, TM | 1 |
| Gu, LQ | 1 |
| Huang, ZS | 1 |
| Li, D | 1 |
| Ovádeková, R | 1 |
| Jantová, S | 1 |
| Letasiová, S | 1 |
| Stepánek, I | 1 |
| Labuda, J | 1 |
| Yang, J | 1 |
| Ljn, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I, Randomized, Crossover, Double-blind, Pharmacokinetic Study of Berberine Released From Cyclodextrin in Healthy Volunteers[NCT04918667] | Phase 1 | 16 participants (Anticipated) | Interventional | 2024-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
31 reviews available for berberine and Neoplasms
| Article | Year |
|---|---|
JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.
Topics: Algorithms; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Discovery; Drug Screening Assays, | 2012 |
Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1.
Topics: Animals; Antineoplastic Agents, Phytogenic; Classification; Cluster Analysis; Cytochrome P-450 CYP1B | 2019 |
Quinolone hybrids and their anti-cancer activities: An overview.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship | 2019 |
Overview of AKR1C3: Inhibitor Achievements and Disease Insights.
Topics: Aldo-Keto Reductase Family 1 Member C3; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cl | 2020 |
Annual review of LSD1/KDM1A inhibitors in 2020.
Topics: Antineoplastic Agents, Phytogenic; Enzyme Inhibitors; Histone Demethylases; Humans; Molecular Struct | 2021 |
Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives.
Topics: Berberine; Biological Products; Curcumin; Emodin; Genistein; Humans; Neoplasms; Pentacyclic Triterpe | 2021 |
Inhibitory Role of Berberine, an Isoquinoline Alkaloid, on NLRP3 Inflammasome Activation for the Treatment of Inflammatory Diseases.
Topics: Animals; Anti-Inflammatory Agents; Berberine; Humans; Inflammasomes; Inflammation; Metabolic Disease | 2021 |
Berberine as a Potential Anticancer Agent: A Comprehensive Review.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Berberine; Cell Cycle; Cell Proliferation; Hum | 2021 |
Effects of Berberine on Leukemia with a Focus on Its Molecular Targets.
Topics: Antineoplastic Agents; Berberine; Drugs, Chinese Herbal; Female; Humans; Leukemia; Male; Neoplasms | 2022 |
Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways.
Topics: Antineoplastic Agents; Apoptosis; Berberine; beta Catenin; Biological Products; Cell Line, Tumor; Ce | 2022 |
Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy.
Topics: Anti-Inflammatory Agents; Berberine; Colitis, Ulcerative; Drug Repositioning; Humans; Inflammation; | 2022 |
Pharmacotherapeutic values of berberine: A Chinese herbal medicine for the human cancer management.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Drugs, Chinese Herbal; Humans; Neoplasms | 2023 |
A review of the chemopreventative and chemotherapeutic properties of the phytochemicals berberine, resveratrol and curcumin, and their influence on cell death via the pathways of apoptosis and autophagy.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Berberine; Curcumin; Humans; Neoplasms; Phytochemicals; | 2020 |
Berberine: A novel therapeutic strategy for cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Berberine; Berberis; Cell Cycle Ch | 2020 |
Berberine-A potent chemosensitizer and chemoprotector to conventional cancer therapies.
Topics: Animals; Antineoplastic Agents; Berberine; Humans; Neoplasms | 2021 |
Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers.
Topics: Animals; Antiviral Agents; Berberine; Carcinogenesis; Clinical Trials as Topic; Herpesviridae; Herpe | 2021 |
Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.
Topics: Berberine; Cardiovascular Diseases; Curcumin; Gene Expression Regulation; Glycogen Synthase Kinase 3 | 2017 |
Regulatory effects of berberine on microRNome in Cancer and other conditions.
Topics: Animals; Apoptosis; Berberine; Cell Proliferation; Gene Expression Regulation; Humans; MicroRNAs; Ne | 2017 |
Sonodynamic therapy: A potential treatment for atherosclerosis.
Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chal | 2018 |
Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Berberine; Berberis; Body Weight; Cricetina | 2019 |
Learning from berberine: Treating chronic diseases through multiple targets.
Topics: Berberine; China; Chronic Disease; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hyperlipidemia | 2015 |
Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development.
Topics: Alkaloids; Amphibian Venoms; Animals; Antineoplastic Agents, Phytogenic; Berberine; Diterpenes; Drug | 2014 |
Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Humans; Neoplasms | 2014 |
Berberine, an epiphany against cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Drug Screening Assays, Antitumor; Humans; Neo | 2014 |
Berberine and Coptidis Rhizoma as potential anticancer agents: Recent updates and future perspectives.
Topics: Animals; Antineoplastic Agents; Berberine; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Humans; | 2015 |
Research progress on berberine with a special focus on its oral bioavailability.
Topics: Administration, Oral; Animals; Berberine; Biological Availability; Diabetes Mellitus; Humans; Hyperl | 2016 |
Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Artemisinins; Artesunate; | 2010 |
Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberidaceae; Berberine; Drug Delivery Systems; Electro | 2011 |
Berberine hydrochloride: anticancer activity and nanoparticulate delivery system.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Drug Delivery Systems; Glucose; Humans; Lipid | 2011 |
Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine.
Topics: Alzheimer Disease; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antimalarials; Antineop | 2011 |
[Advance on study in anti-tumor mechamism of bererine (Ber)].
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cell Proliferation; DNA, Ne | 2007 |
25 other studies available for berberine and Neoplasms
| Article | Year |
|---|---|
Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro.
Topics: A549 Cells; Anti-Inflammatory Agents; Berberine; Cell Proliferation; Humans; Nanoparticles; Neoplasm | 2021 |
Improvement of anticancer effect of berberine by salt formation modifications.
Topics: Animals; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Fatty Acids; Humans; Isoquinoli | 2022 |
Yolk-shell shaped Au-Bi
Topics: Berberine; Bismuth; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Drug Liberation; Gold; Hum | 2022 |
Discovery of berberine analogs as potent and highly selective p300/CBP HAT inhibitors.
Topics: Acetylation; Berberine; Histone Acetyltransferases; Humans; Neoplasms; p300-CBP Transcription Factor | 2023 |
Spatially Resolved Metabolomics Combined with the 3D Tumor-Immune Cell Coculture Spheroid Highlights Metabolic Alterations during Antitumor Immune Response.
Topics: Berberine; Coculture Techniques; Humans; Immunity; Neoplasms; Spheroids, Cellular; Tumor Microenviro | 2023 |
Identification of FtfL as a novel target of berberine in intestinal bacteria.
Topics: Bacteria; Berberine; Humans; Intestines; Neoplasms | 2023 |
Synthesis and anticancer activity of novel 9,13-disubstituted berberine derivatives.
Topics: Berberine; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship | 2020 |
Mitochondria-targeting nanomedicine self-assembled from GSH-responsive paclitaxel-ss-berberine conjugate for synergetic cancer treatment with enhanced cytotoxicity.
Topics: Berberine; Cell Line, Tumor; Drug Delivery Systems; Escherichia coli; Mitochondria; Nanomedicine; Na | 2020 |
Berberine inhibits cancer cells growth by suppressing fatty acid synthesis and biogenesis of extracellular vesicles.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Antineoplastic Agents; Berberine; Blotting, W | 2020 |
[Research progress in mechanism of berberine's antitumor action].
Topics: Berberine; Cell Proliferation; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Neoplas | 2021 |
Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs.
Topics: Algorithms; Antineoplastic Agents; Berberine; Computer Simulation; Hedgehog Proteins; Humans; Hydrog | 2017 |
Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals.
Topics: Animals; Antineoplastic Agents; Berberine; Cardiovascular Diseases; Curcumin; Dietary Supplements; H | 2018 |
Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment.
Topics: Antineoplastic Agents; Berberine; Humans; Molecular Docking Simulation; Mutation; Neoplasms; Protein | 2018 |
Anticancer Efficacy of the Combination of Berberine and PEGylated Liposomal Doxorubicin in Meth A Sarcoma-Bearing Mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Berberine; Cell Line, Tumor; Doxorubicin; D | 2018 |
Cell-specific pattern of berberine pleiotropic effects on different human cell lines.
Topics: Apoptosis; Autophagy; Berberine; Carcinogenesis; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Pr | 2018 |
8-Cetylcoptisine, a new coptisine derivative, induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest in human A549 cells.
Topics: A549 Cells; Animals; Apoptosis; Berberine; Body Weight; Caspase 3; Cell Line, Tumor; Cyclin D; Cycli | 2019 |
Improvement of anti-inflammatory and anti-angiogenic activity of berberine by novel rapid dissolving nanoemulsifying technique.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Berberine; Biological Availability; Chic | 2014 |
[18F-Berberine Derivatives: a Potential Molecular Imaging Agent for Tumor Targeting by PET/CT Tumor].
Topics: Berberine; Fluorodeoxyglucose F18; Humans; Molecular Imaging; Neoplasms; Positron-Emission Tomograph | 2015 |
Hormetic Effect of Berberine Attenuates the Anticancer Activity of Chemotherapeutic Agents.
Topics: Animals; Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Proliferation; Coptis chinensis; D | 2015 |
Berberine induces mitochondrial apoptosis of EBV-transformed B cells through p53-mediated regulation of XAF1 and GADD45α.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Berberine; Cell Cycl | 2016 |
Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes.
Topics: Animals; Antineoplastic Agents; Berberine; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; N | 2017 |
Antitumor effects of the combination of cholesterol reducing drugs.
Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Berberine; Cell Cycle; Cell Line, Tumor; D | 2011 |
Biophysical studies on the effect of the 13 position substitution of the anticancer alkaloid berberine on its DNA binding.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Binding Sites; Calorimetry, Differential Scan | 2012 |
Interaction of Berberine derivative with protein POT1 affect telomere function in cancer cells.
Topics: Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitatio | 2012 |
Nanostructured electrochemical DNA biosensors for detection of the effect of berberine on DNA from cancer cells.
Topics: Berberine; Biosensing Techniques; Cell Line, Tumor; Cobalt; DNA; Electrochemistry; Humans; Molecular | 2006 |