Page last updated: 2024-10-23

berberine and Neoplasms

berberine has been researched along with Neoplasms in 56 studies

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Berberine is a bioactive alkaloid found in herbal plants (e."6.82Effects of Berberine on Leukemia with a Focus on Its Molecular Targets. ( Asemi, Z; Dana, PM; Hallajzadeh, J; Mansournia, MA; Mazandaranian, MR; Yousefi, B, 2022)
" Various in vitro and in vivo studies have reported the anti-inflammatory role of berberine (BRB), an organic heteropentacyclic phytochemical and natural isoquinoline, in inhibiting NLRP3 inflammasome-dependent inflammation against many disorders."5.12Inhibitory Role of Berberine, an Isoquinoline Alkaloid, on NLRP3 Inflammasome Activation for the Treatment of Inflammatory Diseases. ( Abrahamse, H; George, BP; Sarbadhikary, P, 2021)
"Berberine is a bioactive alkaloid found in herbal plants (e."2.82Effects of Berberine on Leukemia with a Focus on Its Molecular Targets. ( Asemi, Z; Dana, PM; Hallajzadeh, J; Mansournia, MA; Mazandaranian, MR; Yousefi, B, 2022)
"Berberine exhibits an anticancer role through scavenging free radicals, induction of apoptosis, cell cycle arrest, inhibition of angiogenesis, inflammation, PI3K/AKT/mammalian target of rapamycin (mTOR), Wnt/β-catenin, and the MAPK/ERK signaling pathway."2.82Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways. ( Almatroodi, SA; Alsahli, MA; Rahmani, AH, 2022)
"Cancer is the second leading cause of death in the world."2.72Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives. ( Akter, R; Bibi, P; Hassan, SSU; Mubin, S; Najda, A; Rahman, MH; Saeeda, S; Shah, M; Wesołowska, S, 2021)
"BBR prevents cancer cell proliferation by inducing apoptosis and controlling the cell cycle as well as autophagy."2.72Berberine as a Potential Anticancer Agent: A Comprehensive Review. ( Abu-Izneid, T; Alhumaydhi, FA; Aljohani, ASM; Emran, TB; Gondal, TA; Imran, M; Jeandet, P; Khalil, AA; Khan, I; Khan, Z; Mitra, S; Rahman, MM; Rauf, A; Shah, ZA, 2021)
"BBR effectively sensitizes refractory cancers to chemotherapy and radiotherapy by ameliorating the diverse events underlying therapy resistance."2.72Berberine-A potent chemosensitizer and chemoprotector to conventional cancer therapies. ( Devarajan, N; Ganesan, SK; Jayaraman, S; Mahendra, J; Palaniappan, H; Rajagopal, P; Venkatratnam, P, 2021)
"Berberine (BBR) is a nature-driven phytochemical component originated from different plant groups such as Berberis vulgaris, Berberis aquifolium, and Berberis aristata."2.66Berberine: A novel therapeutic strategy for cancer. ( Aghebati-Maleki, L; Asenjan, KS; Gholipour, E; Hojjat-Farsangi, M; Motavalli, R; Samadi, P; Sarvarian, P; Yousefi, M, 2020)
"The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant cancers make an urgent need to develop more effective anti-cancer candidates."2.61Quinolone hybrids and their anti-cancer activities: An overview. ( Gao, F; Wang, T; Xiao, J; Zhang, X, 2019)
"00001) in a linear The dose-response relationship (Pearson r = - 0."2.61Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis. ( Long, Y; Ni, L; Tao, J; Wu, R; Xu, J; Yu, N; Yuan, X; Zhang, Y, 2019)
"Berberine (BBR) is an isoquinoline alkaloid found in different plant families such as Berberidaceae, Ranunculaceae, and Papaveraceae."2.55Regulatory effects of berberine on microRNome in Cancer and other conditions. ( Ayati, SH; Cicero, AFG; Fazeli, B; Momtazi-Borojeni, AA; Pirro, M; Sahebkar, A, 2017)
" It is necessary to improve the oral bioavailability of BBR before it can be used in many clinical applications."2.53Research progress on berberine with a special focus on its oral bioavailability. ( Liu, CS; Long, XY; Zhang, YF; Zheng, YR, 2016)
"Unspecified cancer type and staging, fluctuated dose information and variants of targets across studies of berberine/ Coptidis Rhizoma impede their clinical use for cancer treatment."2.52Berberine and Coptidis Rhizoma as potential anticancer agents: Recent updates and future perspectives. ( Feng, Y; Li, L; Tan, HY; Wang, N; Yuen, MF, 2015)
"Cancer is a multifactorial and multistep disease, so the treatment effect of combination formulas and prescriptions in TCMs involving multi-targets and multi-signal pathways on tumor may be superior than that of agents targeting a single molecular target alone."2.50Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development. ( Bai, XY; Wang, CH; Wang, CY, 2014)
"Breast cancer is the most common cancer among women worldwide and novel therapeutic agents are needed to treat this disease."2.50Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer. ( Ismail, P; Jabbarzadeh Kaboli, P; Ling, KH; Rahmat, A, 2014)
"The National Cancer Institute 60 (NCI60), which consists of 60 cell lines from various human cancer types, remains the most powerful human cancer cell line panel for high throughput screening of anticancer drugs."2.48JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs. ( Kong, D; Yamori, T, 2012)
" The present review supplies evidence that berberine is a safe anti-cancer agent, exerting several effects on mitochondria, including inhibition of mitochondrial Complex I and interaction with the adenine nucleotide translocator which can explain several of the described effects on tumor cells."2.47Berberine as a promising safe anti-cancer agent - is there a role for mitochondria? ( Barbosa, IA; Burgeiro, A; Diogo, CV; Machado, NG; Oliveira, PJ; Serafim, TL, 2011)
"Berberine hydrochloride is a conventional component in Chinese medicine, and is characterized by a diversity of pharmacological effects."2.47Berberine hydrochloride: anticancer activity and nanoparticulate delivery system. ( Chen, M; Li, Y; Tan, W; Wang, Y, 2011)
"Berberine is an isoquinoline alkaloid isolated from Chinese herbs such as Coptidis Rhizome."2.47Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine. ( Chen, WM; Huang, ZJ; Lan, P; Sun, PH; Zeng, Y, 2011)
" Here, a 3D tumor-immune cell coculture spheroid model was developed to mimic tumor-immune interactions, combined with mass spectrometry imaging-based spatially resolved metabolomics to visualize tumor immunometabolic alterations during immune response."1.91Spatially Resolved Metabolomics Combined with the 3D Tumor-Immune Cell Coculture Spheroid Highlights Metabolic Alterations during Antitumor Immune Response. ( Chen, P; Chen, X; Han, Y; Sun, C; Wang, L; Wang, X; Zhang, M; Zhao, Y; Zheng, Y; Zhu, Z, 2023)
"Berberine (BBR) is a commonly used anti-intestinal inflammation drug, and its anti-cancer activity has been found recently."1.91Identification of FtfL as a novel target of berberine in intestinal bacteria. ( Fang, C; Fang, J; Gu, Y; Jiang, W; Li, J; Liu, Y; Yan, J; Yang, G; Yang, P; Zhang, L; Zhang, Y, 2023)
"Its anticancer activity in vivo was demonstrated by the mouse xenograft model."1.72Improvement of anticancer effect of berberine by salt formation modifications. ( Liao, Y; Liu, M; Liu, Z; Xu, F; Zeng, Y; Zhang, P; Zhou, Y, 2022)
"Berberine-LCNs were prepared by mixing berberine, monoolein and poloxamer 407 (P407) using ultrasonication method."1.62Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro. ( Chellappan, DK; Dua, K; Hansbro, PM; Malyla, V; Mehta, M; Oliver, BG; Paudel, KR, 2021)
"Berberine is an effective component of rhizoma coptidis, with a very good antitumor effect."1.62[Research progress in mechanism of berberine's antitumor action]. ( Chen, T; Gong, YY; Luo, MJ; Luo, S; Yang, XH; Zhang, LJ, 2021)
"Paclitaxel (PTX) is a broad-spectrum anticancer drug, but its therapeutic effect is highly limited due to the development of multidrug resistance."1.56Mitochondria-targeting nanomedicine self-assembled from GSH-responsive paclitaxel-ss-berberine conjugate for synergetic cancer treatment with enhanced cytotoxicity. ( Cheng, Y; Ji, Y, 2020)
"Berberine is an isoquinoline alkaloid extracted from the root, rhizome and stem bark of Coptidis Rhizoma."1.56Berberine inhibits cancer cells growth by suppressing fatty acid synthesis and biogenesis of extracellular vesicles. ( Gu, S; Huang, D; Li, Q; Liang, B; Ouyang, C; Song, X; Su, T; Xie, L; Xie, R; Xu, M; Xu, T, 2020)
"Lung cancer is the worldwide leading cause of cancer-related death."1.518-Cetylcoptisine, a new coptisine derivative, induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest in human A549 cells. ( Han, B; Jiang, P; Li, X; Liu, L; Liu, W; Ma, W; Wu, S; Xu, H; Ye, X; Zhang, J, 2019)
"Berberine (BBR) is an alkaloid that is widely distributed in different plant species."1.48Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment. ( Ismail, P; Jabbarzadeh Kaboli, P; Ling, KH, 2018)
"Berberine was found to interact with Lys395 of Smo receptor via hydrogen bonding and cation-π interactions."1.46Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs. ( Bazrafkan, M; Ismail, P; Kaboli, PJ; Ling, KH, 2017)
"Berberine (BBR) has shown promising antitumour effects in vitro."1.46Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes. ( Liu, Z; Wang, Q; Wang, X; Zheng, X, 2017)
"Cancer is one of the main causes of death for human beings."1.42[18F-Berberine Derivatives: a Potential Molecular Imaging Agent for Tumor Targeting by PET/CT Tumor]. ( Fan, C; Liang, M; Mei, X; Wu, X; Zhang, T, 2015)
"In a Panc 02 pancreatic cancer model in mice, lovastatin-berberine combination slightly, but significantly, slowed down tumor growth."1.37Antitumor effects of the combination of cholesterol reducing drugs. ( Bil, J; Golab, J; Issat, T; Jakobisiak, M; Nowis, D; Winiarska, M, 2011)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (3.57)29.6817
2010's31 (55.36)24.3611
2020's23 (41.07)2.80

Authors

AuthorsStudies
Kong, D1
Yamori, T1
Mohd Siddique, MU1
Barbhuiya, TK1
Sinha, BN1
Jayaprakash, V1
Gao, F1
Zhang, X2
Wang, T1
Xiao, J1
Liu, Y4
He, S1
Chen, Y1
Feng, F1
Liu, W2
Guo, Q1
Zhao, L1
Sun, H1
Fu, DJ1
Li, J2
Yu, B1
Mehta, M1
Malyla, V1
Paudel, KR1
Chellappan, DK1
Hansbro, PM1
Oliver, BG1
Dua, K1
Akter, R1
Najda, A1
Rahman, MH1
Shah, M1
Wesołowska, S1
Hassan, SSU1
Mubin, S1
Bibi, P1
Saeeda, S1
Sarbadhikary, P1
George, BP1
Abrahamse, H1
Rauf, A1
Abu-Izneid, T1
Khalil, AA1
Imran, M1
Shah, ZA1
Emran, TB1
Mitra, S1
Khan, Z1
Alhumaydhi, FA1
Aljohani, ASM1
Khan, I1
Rahman, MM1
Jeandet, P1
Gondal, TA1
Mazandaranian, MR1
Dana, PM1
Asemi, Z1
Hallajzadeh, J1
Mansournia, MA1
Yousefi, B1
Xu, F1
Liu, M1
Liao, Y1
Zhou, Y2
Zhang, P1
Zeng, Y2
Liu, Z2
Zhao, T1
Zhang, Q1
Cang, F1
Wu, S2
Jiang, Y1
Zhao, Q1
Qu, X1
Jin, Y1
Li, Y2
Fu, Y1
Almatroodi, SA1
Alsahli, MA1
Rahmani, AH1
Zhu, C1
Li, K1
Peng, XX1
Yao, TJ1
Wang, ZY1
Hu, P1
Cai, D1
Liu, HY1
Devarajan, N2
Nathan, J1
Mathangi, R1
Mahendra, J2
Ganesan, SK2
Zhong, X1
Deng, H1
Long, M1
Yin, H1
Zhong, Q1
Zheng, S1
Gong, T1
He, L1
Wang, G1
Sun, Q1
Chen, P1
Han, Y1
Wang, L1
Zheng, Y1
Zhu, Z1
Zhao, Y1
Zhang, M1
Chen, X1
Wang, X2
Sun, C1
Yan, J1
Fang, C1
Yang, G1
Zhang, L1
Yang, P1
Fang, J1
Gu, Y1
Zhang, Y4
Jiang, W1
Wang, ZC1
Wang, J1
Chen, H1
Tang, J1
Bian, AW1
Liu, T1
Yu, LF1
Yi, Z1
Yang, F1
Cheng, Y1
Ji, Y1
D'Arcy, MS1
Gu, S1
Song, X1
Xie, R1
Ouyang, C1
Xie, L1
Li, Q1
Su, T1
Xu, M1
Xu, T1
Huang, D1
Liang, B1
Samadi, P1
Sarvarian, P1
Gholipour, E1
Asenjan, KS1
Aghebati-Maleki, L1
Motavalli, R1
Hojjat-Farsangi, M1
Yousefi, M1
Jayaraman, S1
Venkatratnam, P1
Rajagopal, P1
Palaniappan, H1
Yang, XH1
Zhang, LJ1
Luo, MJ1
Luo, S1
Gong, YY1
Chen, T1
Šudomová, M1
Berchová-Bímová, K1
Marzocco, S1
Liskova, A1
Kubatka, P1
Hassan, STS1
McCubrey, JA2
Lertpiriyapong, K2
Steelman, LS2
Abrams, SL2
Cocco, L2
Ratti, S2
Martelli, AM2
Candido, S2
Libra, M2
Montalto, G2
Cervello, M2
Gizak, A2
Rakus, D2
Ayati, SH1
Fazeli, B1
Momtazi-Borojeni, AA1
Cicero, AFG1
Pirro, M1
Sahebkar, A1
Kaboli, PJ1
Bazrafkan, M1
Ismail, P3
Ling, KH3
Murata, RM1
Rosalen, PL1
Lombardi, P3
Jabbarzadeh Kaboli, P2
Geng, C1
Hidru, TH1
Zhi, L1
Tao, M1
Zou, L2
Chen, C1
Li, H1
Yahuafai, J1
Asai, T1
Oku, N1
Siripong, P1
Agnarelli, A1
Natali, M1
Garcia-Gil, M1
Pesi, R1
Tozzi, MG1
Ippolito, C1
Bernardini, N1
Vignali, R1
Batistoni, R1
Bianucci, AM1
Marracci, S1
Han, B1
Jiang, P1
Xu, H1
Zhang, J1
Liu, L1
Ma, W1
Li, X1
Ye, X1
Xu, J1
Long, Y1
Ni, L1
Yuan, X1
Yu, N1
Wu, R1
Tao, J1
Yao, J1
Kong, W1
Jiang, J1
Pund, S1
Borade, G1
Rasve, G1
Wang, CY1
Bai, XY1
Wang, CH1
Rahmat, A1
Ortiz, LM1
Tillhon, M1
Scovassi, AI1
Mei, X1
Wu, X1
Zhang, T1
Liang, M1
Fan, C1
Bao, J1
Huang, B1
Chen, S2
Zhang, C1
Chen, M2
Wan, JB1
Su, H1
Wang, Y2
He, C1
Wang, N1
Tan, HY1
Li, L1
Yuen, MF1
Feng, Y1
Liu, CS1
Zheng, YR1
Zhang, YF1
Long, XY1
Park, GB1
Park, SH1
Kim, D1
Kim, YS1
Yoon, SH1
Hur, DY1
Wang, Q1
Zheng, X1
Youns, M1
Hoheisel, JD1
Efferth, T1
Diogo, CV1
Machado, NG1
Barbosa, IA1
Serafim, TL1
Burgeiro, A1
Oliveira, PJ1
Issat, T1
Nowis, D1
Bil, J1
Winiarska, M1
Jakobisiak, M1
Golab, J1
Tan, W1
Bhowmik, D1
Hossain, M1
Buzzetti, F1
D'Auria, R1
Kumar, GS1
Huang, ZJ1
Lan, P1
Sun, PH1
Chen, WM1
Xiao, N1
Ma, Y1
Qiu, J1
Tan, JH1
Ou, TM1
Gu, LQ1
Huang, ZS1
Li, D1
Ovádeková, R1
Jantová, S1
Letasiová, S1
Stepánek, I1
Labuda, J1
Yang, J1
Ljn, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I, Randomized, Crossover, Double-blind, Pharmacokinetic Study of Berberine Released From Cyclodextrin in Healthy Volunteers[NCT04918667]Phase 116 participants (Anticipated)Interventional2024-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

31 reviews available for berberine and Neoplasms

ArticleYear
JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.
    Bioorganic & medicinal chemistry, 2012, Mar-15, Volume: 20, Issue:6

    Topics: Algorithms; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Discovery; Drug Screening Assays,

2012
Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Animals; Antineoplastic Agents, Phytogenic; Classification; Cluster Analysis; Cytochrome P-450 CYP1B

2019
Quinolone hybrids and their anti-cancer activities: An overview.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship

2019
Overview of AKR1C3: Inhibitor Achievements and Disease Insights.
    Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20

    Topics: Aldo-Keto Reductase Family 1 Member C3; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cl

2020
Annual review of LSD1/KDM1A inhibitors in 2020.
    European journal of medicinal chemistry, 2021, Mar-15, Volume: 214

    Topics: Antineoplastic Agents, Phytogenic; Enzyme Inhibitors; Histone Demethylases; Humans; Molecular Struct

2021
Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives.
    Molecules (Basel, Switzerland), 2021, Oct-02, Volume: 26, Issue:19

    Topics: Berberine; Biological Products; Curcumin; Emodin; Genistein; Humans; Neoplasms; Pentacyclic Triterpe

2021
Inhibitory Role of Berberine, an Isoquinoline Alkaloid, on NLRP3 Inflammasome Activation for the Treatment of Inflammatory Diseases.
    Molecules (Basel, Switzerland), 2021, Oct-15, Volume: 26, Issue:20

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Humans; Inflammasomes; Inflammation; Metabolic Disease

2021
Berberine as a Potential Anticancer Agent: A Comprehensive Review.
    Molecules (Basel, Switzerland), 2021, Dec-04, Volume: 26, Issue:23

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Berberine; Cell Cycle; Cell Proliferation; Hum

2021
Effects of Berberine on Leukemia with a Focus on Its Molecular Targets.
    Anti-cancer agents in medicinal chemistry, 2022, 08-04, Volume: 22, Issue:15

    Topics: Antineoplastic Agents; Berberine; Drugs, Chinese Herbal; Female; Humans; Leukemia; Male; Neoplasms

2022
Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways.
    Molecules (Basel, Switzerland), 2022, Sep-10, Volume: 27, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Berberine; beta Catenin; Biological Products; Cell Line, Tumor; Ce

2022
Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Anti-Inflammatory Agents; Berberine; Colitis, Ulcerative; Drug Repositioning; Humans; Inflammation;

2022
Pharmacotherapeutic values of berberine: A Chinese herbal medicine for the human cancer management.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Berberine; Drugs, Chinese Herbal; Humans; Neoplasms

2023
A review of the chemopreventative and chemotherapeutic properties of the phytochemicals berberine, resveratrol and curcumin, and their influence on cell death via the pathways of apoptosis and autophagy.
    Cell biology international, 2020, Volume: 44, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Berberine; Curcumin; Humans; Neoplasms; Phytochemicals;

2020
Berberine: A novel therapeutic strategy for cancer.
    IUBMB life, 2020, Volume: 72, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Berberine; Berberis; Cell Cycle Ch

2020
Berberine-A potent chemosensitizer and chemoprotector to conventional cancer therapies.
    Phytotherapy research : PTR, 2021, Volume: 35, Issue:6

    Topics: Animals; Antineoplastic Agents; Berberine; Humans; Neoplasms

2021
Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers.
    Viruses, 2021, 05-28, Volume: 13, Issue:6

    Topics: Animals; Antiviral Agents; Berberine; Carcinogenesis; Clinical Trials as Topic; Herpesviridae; Herpe

2021
Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.
    Advances in biological regulation, 2017, Volume: 65

    Topics: Berberine; Cardiovascular Diseases; Curcumin; Gene Expression Regulation; Glycogen Synthase Kinase 3

2017
Regulatory effects of berberine on microRNome in Cancer and other conditions.
    Critical reviews in oncology/hematology, 2017, Volume: 116

    Topics: Animals; Apoptosis; Berberine; Cell Proliferation; Gene Expression Regulation; Humans; MicroRNAs; Ne

2017
Sonodynamic therapy: A potential treatment for atherosclerosis.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chal

2018
Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis.
    BMC cancer, 2019, Jun-17, Volume: 19, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Berberine; Berberis; Body Weight; Cricetina

2019
Learning from berberine: Treating chronic diseases through multiple targets.
    Science China. Life sciences, 2015, Volume: 58, Issue:9

    Topics: Berberine; China; Chronic Disease; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hyperlipidemia

2015
Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development.
    The American journal of Chinese medicine, 2014, Volume: 42, Issue:3

    Topics: Alkaloids; Amphibian Venoms; Animals; Antineoplastic Agents, Phytogenic; Berberine; Diterpenes; Drug

2014
Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Humans; Neoplasms

2014
Berberine, an epiphany against cancer.
    Molecules (Basel, Switzerland), 2014, Aug-15, Volume: 19, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Drug Screening Assays, Antitumor; Humans; Neo

2014
Berberine and Coptidis Rhizoma as potential anticancer agents: Recent updates and future perspectives.
    Journal of ethnopharmacology, 2015, Dec-24, Volume: 176

    Topics: Animals; Antineoplastic Agents; Berberine; Coptis; Coptis chinensis; Drugs, Chinese Herbal; Humans;

2015
Research progress on berberine with a special focus on its oral bioavailability.
    Fitoterapia, 2016, Volume: 109

    Topics: Administration, Oral; Animals; Berberine; Biological Availability; Diabetes Mellitus; Humans; Hyperl

2016
Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.
    Current drug discovery technologies, 2010, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Artemisinins; Artesunate;

2010
Berberine as a promising safe anti-cancer agent - is there a role for mitochondria?
    Current drug targets, 2011, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberidaceae; Berberine; Drug Delivery Systems; Electro

2011
Berberine hydrochloride: anticancer activity and nanoparticulate delivery system.
    International journal of nanomedicine, 2011, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Drug Delivery Systems; Glucose; Humans; Lipid

2011
Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine.
    Mini reviews in medicinal chemistry, 2011, Volume: 11, Issue:13

    Topics: Alzheimer Disease; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antimalarials; Antineop

2011
[Advance on study in anti-tumor mechamism of bererine (Ber)].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cell Proliferation; DNA, Ne

2007

Other Studies

25 other studies available for berberine and Neoplasms

ArticleYear
Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro.
    Journal of food biochemistry, 2021, Volume: 45, Issue:11

    Topics: A549 Cells; Anti-Inflammatory Agents; Berberine; Cell Proliferation; Humans; Nanoparticles; Neoplasm

2021
Improvement of anticancer effect of berberine by salt formation modifications.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 104

    Topics: Animals; Apoptosis; Berberine; Cell Line, Tumor; Cell Proliferation; Fatty Acids; Humans; Isoquinoli

2022
Yolk-shell shaped Au-Bi
    Nanotechnology, 2022, Aug-23, Volume: 33, Issue:45

    Topics: Berberine; Bismuth; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Drug Liberation; Gold; Hum

2022
Discovery of berberine analogs as potent and highly selective p300/CBP HAT inhibitors.
    Bioorganic chemistry, 2023, Volume: 138

    Topics: Acetylation; Berberine; Histone Acetyltransferases; Humans; Neoplasms; p300-CBP Transcription Factor

2023
Spatially Resolved Metabolomics Combined with the 3D Tumor-Immune Cell Coculture Spheroid Highlights Metabolic Alterations during Antitumor Immune Response.
    Analytical chemistry, 2023, 10-17, Volume: 95, Issue:41

    Topics: Berberine; Coculture Techniques; Humans; Immunity; Neoplasms; Spheroids, Cellular; Tumor Microenviro

2023
Identification of FtfL as a novel target of berberine in intestinal bacteria.
    BMC biology, 2023, Dec-05, Volume: 21, Issue:1

    Topics: Bacteria; Berberine; Humans; Intestines; Neoplasms

2023
Synthesis and anticancer activity of novel 9,13-disubstituted berberine derivatives.
    Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2

    Topics: Berberine; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship

2020
Mitochondria-targeting nanomedicine self-assembled from GSH-responsive paclitaxel-ss-berberine conjugate for synergetic cancer treatment with enhanced cytotoxicity.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, Volume: 318

    Topics: Berberine; Cell Line, Tumor; Drug Delivery Systems; Escherichia coli; Mitochondria; Nanomedicine; Na

2020
Berberine inhibits cancer cells growth by suppressing fatty acid synthesis and biogenesis of extracellular vesicles.
    Life sciences, 2020, Sep-15, Volume: 257

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Antineoplastic Agents; Berberine; Blotting, W

2020
[Research progress in mechanism of berberine's antitumor action].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2021, Volume: 46, Issue:10

    Topics: Berberine; Cell Proliferation; Drugs, Chinese Herbal; Humans; Medicine, Chinese Traditional; Neoplas

2021
Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs.
    Recent patents on anti-cancer drug discovery, 2017, Nov-20, Volume: 12, Issue:4

    Topics: Algorithms; Antineoplastic Agents; Berberine; Computer Simulation; Hedgehog Proteins; Humans; Hydrog

2017
Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals.
    Advances in biological regulation, 2018, Volume: 67

    Topics: Animals; Antineoplastic Agents; Berberine; Cardiovascular Diseases; Curcumin; Dietary Supplements; H

2018
Molecular modeling, dynamics simulations, and binding efficiency of berberine derivatives: A new group of RAF inhibitors for cancer treatment.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Berberine; Humans; Molecular Docking Simulation; Mutation; Neoplasms; Protein

2018
Anticancer Efficacy of the Combination of Berberine and PEGylated Liposomal Doxorubicin in Meth A Sarcoma-Bearing Mice.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Berberine; Cell Line, Tumor; Doxorubicin; D

2018
Cell-specific pattern of berberine pleiotropic effects on different human cell lines.
    Scientific reports, 2018, Jul-13, Volume: 8, Issue:1

    Topics: Apoptosis; Autophagy; Berberine; Carcinogenesis; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Pr

2018
8-Cetylcoptisine, a new coptisine derivative, induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest in human A549 cells.
    Chemico-biological interactions, 2019, Feb-01, Volume: 299

    Topics: A549 Cells; Animals; Apoptosis; Berberine; Body Weight; Caspase 3; Cell Line, Tumor; Cyclin D; Cycli

2019
Improvement of anti-inflammatory and anti-angiogenic activity of berberine by novel rapid dissolving nanoemulsifying technique.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Feb-15, Volume: 21, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Berberine; Biological Availability; Chic

2014
[18F-Berberine Derivatives: a Potential Molecular Imaging Agent for Tumor Targeting by PET/CT Tumor].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2015, Volume: 32, Issue:2

    Topics: Berberine; Fluorodeoxyglucose F18; Humans; Molecular Imaging; Neoplasms; Positron-Emission Tomograph

2015
Hormetic Effect of Berberine Attenuates the Anticancer Activity of Chemotherapeutic Agents.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Proliferation; Coptis chinensis; D

2015
Berberine induces mitochondrial apoptosis of EBV-transformed B cells through p53-mediated regulation of XAF1 and GADD45α.
    International journal of oncology, 2016, Volume: 49, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Berberine; Cell Cycl

2016
Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes.
    The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:6

    Topics: Animals; Antineoplastic Agents; Berberine; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Nude; N

2017
Antitumor effects of the combination of cholesterol reducing drugs.
    Oncology reports, 2011, Volume: 26, Issue:1

    Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Berberine; Cell Cycle; Cell Line, Tumor; D

2011
Biophysical studies on the effect of the 13 position substitution of the anticancer alkaloid berberine on its DNA binding.
    The journal of physical chemistry. B, 2012, Feb-23, Volume: 116, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Binding Sites; Calorimetry, Differential Scan

2012
Interaction of Berberine derivative with protein POT1 affect telomere function in cancer cells.
    Biochemical and biophysical research communications, 2012, Mar-16, Volume: 419, Issue:3

    Topics: Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitatio

2012
Nanostructured electrochemical DNA biosensors for detection of the effect of berberine on DNA from cancer cells.
    Analytical and bioanalytical chemistry, 2006, Volume: 386, Issue:7-8

    Topics: Berberine; Biosensing Techniques; Cell Line, Tumor; Cobalt; DNA; Electrochemistry; Humans; Molecular

2006