Page last updated: 2024-10-23

berberine and Neoplasm Metastasis

berberine has been researched along with Neoplasm Metastasis in 20 studies

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on melanoma cells, including inhibiting cancer viability, blocking cell cycle and migration."7.83Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells. ( Du, B; Kou, Y; Li, B; Li, H; Li, L; Tan, Y; Wang, K, 2016)
"Effects of coptisine on highly metastatic human breast cancer cell MDA-MB-231 proliferation were evaluated by trypan blue assay and on cell adhesion, migration and invasion by gelatin adhesion, wound-healing and matrigel invasion chamber assays, respectively."7.80Suppression of human breast cancer cell metastasis by coptisine in vitro. ( Cao, SP; Chen, SH; Li, J; Qiu, DM; Xia, XL, 2014)
"In this study, we investigated the anti-metastasis mechanisms of berberine in human melanoma cancer A375."5.48Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro. ( Chueh, FS; Chung, JG; Huang, AC; Huang, WW; Huang, YP; Lai, KC; Liu, JF; Maraming, P; Peng, SF, 2018)
"Berberine could suppress the transcription level of Id-1 through inhibiting its promotor activity."5.42Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma. ( Cheung, KC; Cheung, YC; Feng, Y; Lui, VW; Man, K; Tsang, CM; Tsao, SW, 2015)
"Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on melanoma cells, including inhibiting cancer viability, blocking cell cycle and migration."3.83Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells. ( Du, B; Kou, Y; Li, B; Li, H; Li, L; Tan, Y; Wang, K, 2016)
"Effects of coptisine on highly metastatic human breast cancer cell MDA-MB-231 proliferation were evaluated by trypan blue assay and on cell adhesion, migration and invasion by gelatin adhesion, wound-healing and matrigel invasion chamber assays, respectively."3.80Suppression of human breast cancer cell metastasis by coptisine in vitro. ( Cao, SP; Chen, SH; Li, J; Qiu, DM; Xia, XL, 2014)
"Berberine is an effective component extracted from the rhizomes of coptis chinensis and phellodendron chinensis."1.62Berberine inhibited metastasis through miR-145/MMP16 axis in vitro. ( Jiang, Y; Li, J; Pei, M; Wu, L; Zhang, S, 2021)
"KRas is frequently mutated in pancreatic cancers."1.62GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals. ( Abrams, SL; Akula, SM; Candido, S; Cervello, M; Cocco, L; Duda, P; Falzone, L; Gizak, A; Libra, M; Martelli, AM; McCubrey, JA; Meher, AK; Montalto, G; Rakus, D; Ratti, S; Ruvolo, P; Steelman, LS, 2021)
"The biological function of BBR in endometrial cancer (EC) and the underlying molecular mechanisms, however, remain unknown."1.48Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2. ( Wang, Y; Zhang, S, 2018)
"In this study, we investigated the anti-metastasis mechanisms of berberine in human melanoma cancer A375."1.48Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro. ( Chueh, FS; Chung, JG; Huang, AC; Huang, WW; Huang, YP; Lai, KC; Liu, JF; Maraming, P; Peng, SF, 2018)
"Berberine could suppress the transcription level of Id-1 through inhibiting its promotor activity."1.42Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma. ( Cheung, KC; Cheung, YC; Feng, Y; Lui, VW; Man, K; Tsang, CM; Tsao, SW, 2015)
"Berberine has several anti-inflammation and anticancer biologic effects."1.40Berberine reverses epithelial-to-mesenchymal transition and inhibits metastasis and tumor-induced angiogenesis in human cervical cancer cells. ( Chen, KS; Chen, PN; Chu, SC; Hsu, LS; Su, MY; Yu, CC, 2014)
"Berberine treatment also decreased various biochemical parameters associated with lung metastasis."1.38Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells. ( Hamsa, TP; Kuttan, G, 2012)
"Berberine is an active ingredient extracted from Coptidis rhizoma which has been used for centuries as a traditional Chinese medicine for treatment of inflammatory diseases."1.35Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells. ( Cheung, AL; Cheung, PY; Ching, YP; Di, K; Feng, Y; Hau, PM; Lau, EP; Tong, Y; Tsang, CM; Tsao, SW; Wan, TS; Wong, YC, 2009)
"Berberine treatment in vivo resulted in a 51."1.35Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567. ( Cao, Y; Chen, Y; Deng, F; Duan, C; He, Z; Huang, D; Liu, S; Meng, J; Tang, F; Tian, D; Wang, D; Wang, L; Wang, W; Wu, B; Wu, Y; Xie, C; Zhu, F, 2009)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (15.00)29.6817
2010's12 (60.00)24.3611
2020's5 (25.00)2.80

Authors

AuthorsStudies
Cheng, CS1
Tan, HY1
Zhang, C1
Chan, YT1
Zhang, ZJ1
Man, K2
Yuen, MF1
Wang, N1
Feng, Y3
Liu, J1
Luo, X1
Guo, R1
Jing, W1
Lu, H1
Li, J3
Zhang, S2
Wu, L1
Pei, M1
Jiang, Y1
Zhao, Y1
Yang, X1
Zhao, J1
Gao, M1
Zhang, M1
Shi, T1
Zhang, F1
Zheng, X1
Pan, Y1
Shao, D1
He, K1
Chen, L1
Abrams, SL1
Akula, SM1
Meher, AK1
Steelman, LS1
Gizak, A1
Duda, P1
Rakus, D1
Martelli, AM1
Ratti, S1
Cocco, L1
Montalto, G1
Cervello, M1
Ruvolo, P1
Libra, M1
Falzone, L1
Candido, S1
McCubrey, JA1
Wang, Y1
Liu, JF1
Lai, KC1
Peng, SF1
Maraming, P1
Huang, YP1
Huang, AC1
Chueh, FS1
Huang, WW1
Chung, JG1
Qi, HW1
Xin, LY1
Xu, X1
Ji, XX1
Fan, LH1
Qiu, DM1
Chen, SH1
Cao, SP1
Xia, XL1
Chu, SC1
Yu, CC1
Hsu, LS1
Chen, KS1
Su, MY1
Chen, PN1
Luo, Z1
Zeng, W1
Tang, W1
Long, T1
Zhang, J1
Xie, X1
Kuang, Y1
Chen, M1
Su, J1
Chen, X1
Tsang, CM2
Cheung, KC1
Cheung, YC1
Lui, VW1
Tsao, SW2
Liu, X1
Ji, Q1
Ye, N1
Sui, H1
Zhou, L1
Zhu, H1
Fan, Z1
Cai, J1
Li, Q1
Kou, Y1
Li, L1
Li, H1
Tan, Y1
Li, B1
Wang, K1
Du, B1
Lau, EP1
Di, K1
Cheung, PY1
Hau, PM1
Ching, YP1
Wong, YC1
Cheung, AL1
Wan, TS1
Tong, Y1
Tang, F2
Wang, D1
Duan, C1
Huang, D2
Wu, Y1
Chen, Y2
Wang, W2
Xie, C2
Meng, J2
Wang, L2
Wu, B1
Liu, S1
Tian, D1
Zhu, F1
He, Z1
Deng, F1
Cao, Y1
Feng, Z1
Hamsa, TP1
Kuttan, G1
Tillhon, M1
Guamán Ortiz, LM1
Lombardi, P1
Scovassi, AI1
Matsuo, M1
Sakurai, H1
Koizumi, K1
Saiki, I1

Reviews

1 review available for berberine and Neoplasm Metastasis

ArticleYear
Berberine: new perspectives for old remedies.
    Biochemical pharmacology, 2012, Nov-15, Volume: 84, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Auto

2012

Other Studies

19 other studies available for berberine and Neoplasm Metastasis

ArticleYear
Berberine suppresses metastasis and recurrence of hepatocellular carcinoma by targeting circulating tumour cells: abridged secondary publication.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2022, Volume: 28 Suppl 6, Issue:6

    Topics: Berberine; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Neoplasm Metastasis

2022
Cell Metabolomics Reveals Berberine-Inhibited Pancreatic Cancer Cell Viability and Metastasis by Regulating Citrate Metabolism.
    Journal of proteome research, 2020, 09-04, Volume: 19, Issue:9

    Topics: Berberine; Cell Survival; Citrates; Humans; Metabolome; Metabolomics; Neoplasm Metastasis; Pancreati

2020
Berberine inhibited metastasis through miR-145/MMP16 axis in vitro.
    Journal of ovarian research, 2021, Jan-06, Volume: 14, Issue:1

    Topics: Berberine; Cell Line, Tumor; Female; Humans; Matrix Metalloproteinase 16; MicroRNAs; Neoplasm Metast

2021
Berberine inhibits chemotherapy-exacerbated ovarian cancer stem cell-like characteristics and metastasis through GLI1.
    European journal of pharmacology, 2021, Mar-15, Volume: 895

    Topics: Antineoplastic Agents; Berberine; Carboplatin; Cell Line, Tumor; Cell Movement; Coculture Techniques

2021
GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals.
    Cells, 2021, 04-06, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Adenylate Kinase; Antineoplastic Agents; bcl-X Protein; Berberine; Biphenyl Compound

2021
Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Animals; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygena

2018
Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro.
    Molecules (Basel, Switzerland), 2018, Aug-13, Volume: 23, Issue:8

    Topics: Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Resistance, Neop

2018
Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis.
    Journal of translational medicine, 2014, Jan-24, Volume: 12

    Topics: Animals; Apoptosis; Berberine; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferatio

2014
Suppression of human breast cancer cell metastasis by coptisine in vitro.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:14

    Topics: Berberine; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Col

2014
Berberine reverses epithelial-to-mesenchymal transition and inhibits metastasis and tumor-induced angiogenesis in human cervical cancer cells.
    Molecular pharmacology, 2014, Volume: 86, Issue:6

    Topics: Animals; Berberine; beta Catenin; Cell Line, Tumor; Cell Movement; Chickens; Chorioallantoic Membran

2014
CD147 interacts with NDUFS6 in regulating mitochondrial complex I activity and the mitochondrial apoptotic pathway in human malignant melanoma cells.
    Current molecular medicine, 2014, Volume: 14, Issue:10

    Topics: Apoptosis; Basigin; Berberine; Cell Line, Tumor; Cell Nucleus; Electron Transport Complex I; Gene Ex

2014
Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:3

    Topics: Animals; Berberine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Gene Expression

2015
Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cell Movement; Colon; Color

2015
Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells.
    Biochemical and biophysical research communications, 2016, Oct-14, Volume: 479, Issue:2

    Topics: Animals; Antineoplastic Agents; Berberine; Chromones; Epithelial-Mesenchymal Transition; Gene Expres

2016
Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells.
    International journal of molecular medicine, 2009, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Do

2009
Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567.
    The Journal of biological chemistry, 2009, Oct-02, Volume: 284, Issue:40

    Topics: Animals; Antineoplastic Agents; Berberine; Cell Line, Tumor; Cytoskeletal Proteins; Enzyme Activatio

2009
Berberine inhibits the invasion and metastasis of nasopharyngeal carcinoma cells through Ezrin phosphorylation.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cytoskeletal Proteins; Humans; Nasop

2011
Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:4

    Topics: Activating Transcription Factor 2; Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line,

2012
Curcumin inhibits the formation of capillary-like tubes by rat lymphatic endothelial cells.
    Cancer letters, 2007, Jun-28, Volume: 251, Issue:2

    Topics: Animals; Berberine; Capillaries; Cell Adhesion; Cell Line, Tumor; Cell Survival; Curcumin; Dose-Resp

2007