berberine has been researched along with Multiple Myeloma in 9 studies
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent studies have suggested the potency of berberine (BBR) for multiple cancer treatments, including multiple myeloma (MM)." | 8.12 | Discovery of the oncogenic MDM2, a direct binding target of berberine and a potential therapeutic, in multiple myeloma. ( Fei, J; Gu, C; Huang, G; Li, C; Liu, Y; Su, R; Wang, X; Yang, J; Yin, Z, 2022) |
| "Berberine downregulated miR-19a/92a cluster expression in multiple myeloma (MM) cells." | 7.88 | Signal pathways, diseases, and functions associated with the miR-19a/92a cluster and the use of berberine to modulate the expression of this cluster in multiple myeloma cells. ( Fei, J; Feng, M; Gu, C; Li, Y; Liu, Y; Ning, R; Yang, J; Yin, Z, 2018) |
| "Our results suggest that berberine suppresses multiple myeloma cell growth, at least in part, by down-regulating miR-21 levels possibly through IL6/STAT3." | 7.80 | Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine. ( Fei, J; Feng, M; Gu, J; Li, Y; Luo, X; Zhu, R; Zhu, X, 2014) |
| "To investigate the mechanisms by which berberine suppressed the proliferation of human multiple myeloma cells." | 7.79 | Set9, NF-κB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells. ( Dong, RH; Guo, HB; Hu, HY; Li, KP; Liu, Y; Lu, ZG; Wang, XJ; Zhang, MX, 2013) |
| "Current therapies for multiple myeloma (MM) are associated with toxicity and resistance, highlighting the need for novel effective therapeutics." | 5.56 | Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1. ( Chen, L; Fei, J; Gu, C; Huang, G; Liu, Y; Nie, H; Shen, J; Yang, J; Yin, Z, 2020) |
| "Berberine (BBR) is a natural alkaloid derived from a traditional Chinese herbal medicine." | 5.42 | Systematic analysis of berberine-induced signaling pathway between miRNA clusters and mRNAs and identification of mir-99a ∼ 125b cluster function by seed-targeting inhibitors in multiple myeloma cells. ( Fei, J; Feng, M; Gu, C; Li, Y; Luo, X; Zhu, X, 2015) |
| "Berberine has multiple pharmacological activities, such as anti-oxidative, anti-inflammation and anticancer activity." | 5.40 | Berberine induces apoptosis in human multiple myeloma cell line U266 through hypomethylation of p53 promoter. ( Feng, T; Hu, H; Jiang, L; Liu, Y; Meng, W; Qing, Y; Sun, Y; Yao, Y, 2014) |
| "Recent studies have suggested the potency of berberine (BBR) for multiple cancer treatments, including multiple myeloma (MM)." | 4.12 | Discovery of the oncogenic MDM2, a direct binding target of berberine and a potential therapeutic, in multiple myeloma. ( Fei, J; Gu, C; Huang, G; Li, C; Liu, Y; Su, R; Wang, X; Yang, J; Yin, Z, 2022) |
| "Berberine downregulated miR-19a/92a cluster expression in multiple myeloma (MM) cells." | 3.88 | Signal pathways, diseases, and functions associated with the miR-19a/92a cluster and the use of berberine to modulate the expression of this cluster in multiple myeloma cells. ( Fei, J; Feng, M; Gu, C; Li, Y; Liu, Y; Ning, R; Yang, J; Yin, Z, 2018) |
| "Our results suggest that berberine suppresses multiple myeloma cell growth, at least in part, by down-regulating miR-21 levels possibly through IL6/STAT3." | 3.80 | Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine. ( Fei, J; Feng, M; Gu, J; Li, Y; Luo, X; Zhu, R; Zhu, X, 2014) |
| "To investigate the mechanisms by which berberine suppressed the proliferation of human multiple myeloma cells." | 3.79 | Set9, NF-κB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells. ( Dong, RH; Guo, HB; Hu, HY; Li, KP; Liu, Y; Lu, ZG; Wang, XJ; Zhang, MX, 2013) |
| "Current therapies for multiple myeloma (MM) are associated with toxicity and resistance, highlighting the need for novel effective therapeutics." | 1.56 | Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1. ( Chen, L; Fei, J; Gu, C; Huang, G; Liu, Y; Nie, H; Shen, J; Yang, J; Yin, Z, 2020) |
| "Berberine (BBR) is a natural alkaloid derived from a traditional Chinese herbal medicine." | 1.42 | Systematic analysis of berberine-induced signaling pathway between miRNA clusters and mRNAs and identification of mir-99a ∼ 125b cluster function by seed-targeting inhibitors in multiple myeloma cells. ( Fei, J; Feng, M; Gu, C; Li, Y; Luo, X; Zhu, X, 2015) |
| "Berberine has multiple pharmacological activities, such as anti-oxidative, anti-inflammation and anticancer activity." | 1.40 | Berberine induces apoptosis in human multiple myeloma cell line U266 through hypomethylation of p53 promoter. ( Feng, T; Hu, H; Jiang, L; Liu, Y; Meng, W; Qing, Y; Sun, Y; Yao, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Su, R | 1 |
| Wang, X | 1 |
| Huang, G | 2 |
| Liu, Y | 5 |
| Yang, J | 3 |
| Yin, Z | 4 |
| Gu, C | 5 |
| Fei, J | 6 |
| Nie, H | 1 |
| Shen, J | 2 |
| Chen, L | 1 |
| Ning, R | 1 |
| Feng, M | 3 |
| Li, Y | 3 |
| Qing, Y | 1 |
| Hu, H | 1 |
| Feng, T | 1 |
| Meng, W | 1 |
| Jiang, L | 1 |
| Sun, Y | 1 |
| Yao, Y | 1 |
| Luo, X | 2 |
| Gu, J | 1 |
| Zhu, R | 1 |
| Zhu, X | 2 |
| Li, T | 1 |
| Chen, S | 1 |
| Zhang, Y | 1 |
| Hu, HY | 1 |
| Li, KP | 1 |
| Wang, XJ | 1 |
| Lu, ZG | 1 |
| Dong, RH | 1 |
| Guo, HB | 1 |
| Zhang, MX | 1 |
| Wu, SN | 1 |
| Yu, HS | 1 |
| Jan, CR | 1 |
| Li, HF | 1 |
| Yu, CL | 1 |
9 other studies available for berberine and Multiple Myeloma
| Article | Year |
|---|---|
Discovery of the oncogenic MDM2, a direct binding target of berberine and a potential therapeutic, in multiple myeloma.
Topics: Animals; Apoptosis; Berberine; Bortezomib; Carcinogenesis; Cell Line, Tumor; Humans; Mice; Molecular | 2022 |
Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1.
Topics: Animals; Anticarcinogenic Agents; Berberine; Cell Line, Tumor; Humans; Mice; Mice, Inbred BALB C; Mi | 2020 |
Signal pathways, diseases, and functions associated with the miR-19a/92a cluster and the use of berberine to modulate the expression of this cluster in multiple myeloma cells.
Topics: Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; Gene | 2018 |
Berberine induces apoptosis in human multiple myeloma cell line U266 through hypomethylation of p53 promoter.
Topics: Apoptosis; Berberine; Cell Line, Tumor; DNA Methylation; Humans; Multiple Myeloma; Promoter Regions, | 2014 |
Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Berberine; Cell Line, Tumor; Cell P | 2014 |
Systematic analysis of berberine-induced signaling pathway between miRNA clusters and mRNAs and identification of mir-99a ∼ 125b cluster function by seed-targeting inhibitors in multiple myeloma cells.
Topics: Alkaloids; Berberine; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Humans; MicroRNAs; Multiple | 2015 |
Integrative analysis of signaling pathways and diseases associated with the miR-106b/25 cluster and their function study in berberine-induced multiple myeloma cells.
Topics: Berberine; Cell Line, Tumor; Humans; MicroRNAs; Multiple Myeloma; Signal Transduction | 2017 |
Set9, NF-κB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Cell Line, Tumor; Cell Survival; Gene Expre | 2013 |
Inhibitory effects of berberine on voltage- and calcium-activated potassium currents in human myeloma cells.
Topics: Antineoplastic Agents; Berberine; Calcium; Cell Division; Humans; Membrane Potentials; Multiple Myel | 1998 |