berberine has been researched along with Melanoma in 12 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on melanoma cells, including inhibiting cancer viability, blocking cell cycle and migration." | 7.83 | Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells. ( Du, B; Kou, Y; Li, B; Li, H; Li, L; Tan, Y; Wang, K, 2016) |
| "Melanoma is the most lethal form of skin cancer, and its incidence has increased considerably in the last decades." | 5.72 | Berberine increases the expression of cytokines and proteins linked to apoptosis in human melanoma cells. ( Assmann, CE; Bianchin, NB; das Neves Oliveira, M; de Andrade, CM; de Oliveira, JS; Morsch, VM; Palma, TV; Pillat, MM; Schetinger, MRC; Ulrich, H, 2022) |
| "Berberine is an isoquinoline alkaloid, which has been reported to show high photosensitizing activity." | 5.62 | Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways. ( Fang, J; Gong, Q; Huang, X; Liang, X; Liu, J; Song, C; Wang, X; Yang, Y, 2021) |
| "Malignant melanoma is a critical and aggressive skin tumor with a steeply rising incidence and a less favorable prognosis due to the lack of efficient treatment." | 5.62 | Berberine-photodynamic induced apoptosis by activating endoplasmic reticulum stress-autophagy pathway involving CHOP in human malignant melanoma cells. ( Fang, J; Huang, X; Liang, X; Liu, J; Wang, X; Yang, Y, 2021) |
| "In this study, we investigated the anti-metastasis mechanisms of berberine in human melanoma cancer A375." | 5.48 | Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro. ( Chueh, FS; Chung, JG; Huang, AC; Huang, WW; Huang, YP; Lai, KC; Liu, JF; Maraming, P; Peng, SF, 2018) |
| "Berberine (BBR) is a naturally occurring alkaloid compound that can be found in Chinese medicinal herbs such as Rhizoma Coptidis and Phellodendri Cortex." | 5.46 | Computational and experimental prediction of molecules involved in the anti-melanoma action of berberine. ( Fu, XQ; Guo, H; Li, T; Liu, B; Liu, SM; Su, T; Tse, AK; Yu, ZL; Zhu, PL, 2017) |
| " Herein, we studied the anticancer effects of berberine, a plant alkaloid, in combination with doxorubicin on murine melanoma B16F10 cells in vitro and in vivo." | 5.40 | Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft. ( Mittal, A; Singh, RP; Tabasum, S, 2014) |
| "Malignant melanoma is the most aggressive form of skin cancer." | 5.39 | Jatrorrhizine hydrochloride inhibits the proliferation and neovascularization of C8161 metastatic melanoma cells. ( Cao, Z; Guo, P; Liu, R; Pan, Y; Yang, P; Zhang, G; Zhou, Q, 2013) |
| "Melanoma is the leading cause of death from skin disease due, in large part, to its propensity to metastasize." | 5.37 | Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E₂ and prostaglandin E₂ receptors. ( Katiyar, N; Katiyar, SK; Sharma, S; Singh, T; Vaid, M, 2011) |
| "Berberine is a natural compound extracted from Coptidis rhizoma, and accumulating proof has shown its potent anti-tumor properties with diverse action on melanoma cells, including inhibiting cancer viability, blocking cell cycle and migration." | 3.83 | Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells. ( Du, B; Kou, Y; Li, B; Li, H; Li, L; Tan, Y; Wang, K, 2016) |
| "Melanoma is the most lethal form of skin cancer, and its incidence has increased considerably in the last decades." | 1.72 | Berberine increases the expression of cytokines and proteins linked to apoptosis in human melanoma cells. ( Assmann, CE; Bianchin, NB; das Neves Oliveira, M; de Andrade, CM; de Oliveira, JS; Morsch, VM; Palma, TV; Pillat, MM; Schetinger, MRC; Ulrich, H, 2022) |
| "Berberine is an isoquinoline alkaloid, which has been reported to show high photosensitizing activity." | 1.62 | Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways. ( Fang, J; Gong, Q; Huang, X; Liang, X; Liu, J; Song, C; Wang, X; Yang, Y, 2021) |
| "In this study, we investigated the anti-metastasis mechanisms of berberine in human melanoma cancer A375." | 1.48 | Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro. ( Chueh, FS; Chung, JG; Huang, AC; Huang, WW; Huang, YP; Lai, KC; Liu, JF; Maraming, P; Peng, SF, 2018) |
| "Malignant melanoma has exhibited a rising incidence in recent years worldwide." | 1.46 | Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma. ( Hayakawa, Y; Saiki, I; Xu, X; Yokoyama, S, 2017) |
| "Berberine (BBR) is a naturally occurring alkaloid compound that can be found in Chinese medicinal herbs such as Rhizoma Coptidis and Phellodendri Cortex." | 1.46 | Computational and experimental prediction of molecules involved in the anti-melanoma action of berberine. ( Fu, XQ; Guo, H; Li, T; Liu, B; Liu, SM; Su, T; Tse, AK; Yu, ZL; Zhu, PL, 2017) |
| " Herein, we studied the anticancer effects of berberine, a plant alkaloid, in combination with doxorubicin on murine melanoma B16F10 cells in vitro and in vivo." | 1.40 | Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft. ( Mittal, A; Singh, RP; Tabasum, S, 2014) |
| "Malignant melanoma is the most aggressive form of skin cancer." | 1.39 | Jatrorrhizine hydrochloride inhibits the proliferation and neovascularization of C8161 metastatic melanoma cells. ( Cao, Z; Guo, P; Liu, R; Pan, Y; Yang, P; Zhang, G; Zhou, Q, 2013) |
| "Melanoma is the leading cause of death from skin disease due, in large part, to its propensity to metastasize." | 1.37 | Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E₂ and prostaglandin E₂ receptors. ( Katiyar, N; Katiyar, SK; Sharma, S; Singh, T; Vaid, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palma, TV | 1 |
| Bianchin, NB | 1 |
| de Oliveira, JS | 1 |
| Assmann, CE | 1 |
| das Neves Oliveira, M | 1 |
| Schetinger, MRC | 1 |
| Morsch, VM | 1 |
| Ulrich, H | 1 |
| Pillat, MM | 1 |
| de Andrade, CM | 1 |
| Wang, X | 2 |
| Gong, Q | 1 |
| Song, C | 1 |
| Fang, J | 2 |
| Yang, Y | 2 |
| Liang, X | 2 |
| Huang, X | 2 |
| Liu, J | 2 |
| Xu, X | 1 |
| Yokoyama, S | 1 |
| Hayakawa, Y | 1 |
| Saiki, I | 1 |
| Liu, B | 1 |
| Fu, XQ | 1 |
| Li, T | 1 |
| Su, T | 1 |
| Guo, H | 1 |
| Zhu, PL | 1 |
| Tse, AK | 1 |
| Liu, SM | 1 |
| Yu, ZL | 1 |
| Liu, JF | 1 |
| Lai, KC | 1 |
| Peng, SF | 1 |
| Maraming, P | 1 |
| Huang, YP | 1 |
| Huang, AC | 1 |
| Chueh, FS | 1 |
| Huang, WW | 1 |
| Chung, JG | 1 |
| Liu, R | 1 |
| Cao, Z | 1 |
| Pan, Y | 1 |
| Zhang, G | 1 |
| Yang, P | 1 |
| Guo, P | 1 |
| Zhou, Q | 1 |
| Mittal, A | 1 |
| Tabasum, S | 1 |
| Singh, RP | 1 |
| Luo, Z | 1 |
| Zeng, W | 1 |
| Tang, W | 1 |
| Long, T | 1 |
| Zhang, J | 1 |
| Xie, X | 1 |
| Kuang, Y | 1 |
| Chen, M | 1 |
| Su, J | 1 |
| Chen, X | 1 |
| Kou, Y | 1 |
| Li, L | 1 |
| Li, H | 1 |
| Tan, Y | 1 |
| Li, B | 1 |
| Wang, K | 1 |
| Du, B | 1 |
| Singh, T | 1 |
| Vaid, M | 1 |
| Katiyar, N | 1 |
| Sharma, S | 1 |
| Katiyar, SK | 1 |
| Burgeiro, A | 1 |
| Gajate, C | 1 |
| Dakir, el H | 1 |
| Villa-Pulgarín, JA | 1 |
| Oliveira, PJ | 1 |
| Mollinedo, F | 1 |
12 other studies available for berberine and Melanoma
| Article | Year |
|---|---|
Berberine increases the expression of cytokines and proteins linked to apoptosis in human melanoma cells.
Topics: Apoptosis; Berberine; Cell Line, Tumor; Cytokines; Humans; Melanoma | 2022 |
Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Berberine; Cell Line, Tumor; Cell P | 2021 |
Berberine-photodynamic induced apoptosis by activating endoplasmic reticulum stress-autophagy pathway involving CHOP in human malignant melanoma cells.
Topics: Apoptosis; Autophagy; Berberine; Blotting, Western; Cell Line, Tumor; Endoplasmic Reticulum Stress; | 2021 |
Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonis | 2017 |
Computational and experimental prediction of molecules involved in the anti-melanoma action of berberine.
Topics: Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dihydroorotat | 2017 |
Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro.
Topics: Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Resistance, Neop | 2018 |
Jatrorrhizine hydrochloride inhibits the proliferation and neovascularization of C8161 metastatic melanoma cells.
Topics: Animals; Berberine; Cell Line, Tumor; Growth Inhibitors; Humans; Melanoma; Mice; Mice, Inbred BALB C | 2013 |
Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Caspase 3; Cell Cycle; Cell Line, | 2014 |
CD147 interacts with NDUFS6 in regulating mitochondrial complex I activity and the mitochondrial apoptotic pathway in human malignant melanoma cells.
Topics: Apoptosis; Basigin; Berberine; Cell Line, Tumor; Cell Nucleus; Electron Transport Complex I; Gene Ex | 2014 |
Berberine suppressed epithelial mesenchymal transition through cross-talk regulation of PI3K/AKT and RARα/RARβ in melanoma cells.
Topics: Animals; Antineoplastic Agents; Berberine; Chromones; Epithelial-Mesenchymal Transition; Gene Expres | 2016 |
Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E₂ and prostaglandin E₂ receptors.
Topics: Antineoplastic Agents; Berberine; Blotting, Western; Cell Line, Tumor; Cell Movement; Cyclooxygenase | 2011 |
Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells.
Topics: Adenine Nucleotides; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Blotting, Western; Cas | 2011 |