Page last updated: 2024-10-23

berberine and Malaria

berberine has been researched along with Malaria in 6 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
" In this study, a new semi-synthetic berberine analogue, 5,6-didehydro-8,8-diethyl-13-oxodihydroberberine chloride (1), showed nanomolar level potency against in vitro models of leishmaniasis, malaria, and trypanosomiasis as well as activity in an in vivo visceral leishmaniasis model."3.77Potent antiprotozoal activity of a novel semi-synthetic berberine derivative. ( Anklin, C; Bahar, M; Deng, Y; Doskotch, RW; Drew, ME; Gil, RR; He, S; Kinghorn, AD; Navarro-Vázquez, A; Pandharkar, T; Werbovetz, KA; Zhu, X, 2011)
"Berberine is an isoquinoline alkaloid isolated from Chinese herbs such as Coptidis Rhizome."2.47Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine. ( Chen, WM; Huang, ZJ; Lan, P; Sun, PH; Zeng, Y, 2011)
"KRas is frequently mutated in pancreatic cancers."1.62GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals. ( Abrams, SL; Akula, SM; Candido, S; Cervello, M; Cocco, L; Duda, P; Falzone, L; Gizak, A; Libra, M; Martelli, AM; McCubrey, JA; Meher, AK; Montalto, G; Rakus, D; Ratti, S; Ruvolo, P; Steelman, LS, 2021)
" The orally bioavailable lead imidazolopiperazine confers complete causal prophylactic protection (15 milligrams/kilogram) in rodent models of malaria and shows potent in vivo blood-stage therapeutic activity."1.37Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. ( Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Meister, S1
Plouffe, DM1
Kuhen, KL1
Bonamy, GM1
Wu, T1
Barnes, SW1
Bopp, SE1
Borboa, R1
Bright, AT1
Che, J1
Cohen, S1
Dharia, NV1
Gagaring, K1
Gettayacamin, M1
Gordon, P1
Groessl, T1
Kato, N1
Lee, MC1
McNamara, CW1
Fidock, DA1
Nagle, A1
Nam, TG1
Richmond, W1
Roland, J1
Rottmann, M1
Zhou, B1
Froissard, P1
Glynne, RJ1
Mazier, D1
Sattabongkot, J1
Schultz, PG1
Tuntland, T1
Walker, JR1
Zhou, Y1
Chatterjee, A1
Diagana, TT1
Winzeler, EA1
Abrams, SL1
Akula, SM1
Meher, AK1
Steelman, LS1
Gizak, A1
Duda, P1
Rakus, D1
Martelli, AM1
Ratti, S1
Cocco, L1
Montalto, G1
Cervello, M1
Ruvolo, P1
Libra, M1
Falzone, L1
Candido, S1
McCubrey, JA1
Kume, A1
Herbas, MS1
Shichiri, M1
Ishida, N1
Suzuki, H1
Bahar, M1
Deng, Y1
Zhu, X1
He, S1
Pandharkar, T1
Drew, ME1
Navarro-Vázquez, A1
Anklin, C1
Gil, RR1
Doskotch, RW1
Werbovetz, KA1
Kinghorn, AD1
Huang, ZJ1
Zeng, Y1
Lan, P1
Sun, PH1
Chen, WM1
Talwalkar, SS1
Vaidya, AB1
Godse, C1
Vaidya, A1
Vaidya, R1

Reviews

1 review available for berberine and Malaria

ArticleYear
Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine.
    Mini reviews in medicinal chemistry, 2011, Volume: 11, Issue:13

    Topics: Alzheimer Disease; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antimalarials; Antineop

2011

Other Studies

5 other studies available for berberine and Malaria

ArticleYear
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resista

2011
GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals.
    Cells, 2021, 04-06, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Adenylate Kinase; Antineoplastic Agents; bcl-X Protein; Berberine; Biphenyl Compound

2021
Effect of anti-hyperlipidemia drugs on the alpha-tocopherol concentration and their potential for murine malaria infection.
    Parasitology research, 2016, Volume: 115, Issue:1

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antimalarials; Berberine; Cholestyramine Resin;

2016
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
    Bioorganic & medicinal chemistry letters, 2011, May-01, Volume: 21, Issue:9

    Topics: Animals; Antiprotozoal Agents; Berberine; Chlorocebus aethiops; Disease Models, Animal; Inhibitory C

2011
Plasmodium DNA fluoresces with berberine: a novel approach for diagnosis of malarial parasites.
    American journal of clinical pathology, 2005, Volume: 124, Issue:3

    Topics: Animals; Berberine; DNA, Protozoan; Fluorescence; Humans; Malaria; Plasmodium; Staining and Labeling

2005