berberine has been researched along with Kidney Diseases in 17 studies
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine acts via multiple pathways to alleviate fibrosis in various tissues and shows renoprotective effects." | 8.31 | Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction. ( Gao, Z; Han, B; Hou, Y; Shi, H; Tan, E; Wang, L; Wang, Q; Zhu, G, 2023) |
| "The nephroprotective effects of berberine were mediated in part by downregulating P2X7R and modulating DUSP6-mediated inactivation of ERK1/2 as well as by suppressing SIRT2/MDM2-triggered renal fibrosis." | 8.12 | Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats. ( Ahmedy, OA; Al-Mokaddem, AK; El-Said, YAM; El-Tanbouly, DM, 2022) |
| "Berberine (BBR) is an active component of Phellodendri Cortex (PC), which is a traditional Chinese medicine that has been prescribed clinically for hyperuricemia (HUA) for hundreds of years." | 8.02 | Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model. ( Chen, J; Huang, Z; Li, Q; Li, Y; Liu, D; Su, Z; Xie, J; Zeng, H; Zheng, J, 2021) |
| "To investigate the potential effects of berberine on renal interstitial fibrosis (RIF) of obstructed kidneys in a unilateral ureteral obstruction (UUO) rat model." | 7.80 | Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats. ( He, YQ; Ma, LL; Tian, XJ; Wang, FM; Yang, YJ, 2014) |
| " However, BBR exhibits low bioavailability due to its extensive metabolism and limited absorption." | 5.62 | Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway. ( Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q, 2021) |
| "Berberine (BBR) has been reported in several studies in cell and animal models." | 5.42 | Protective effects of berberine on high fat-induced kidney damage by increasing serum adiponectin and promoting insulin sensitivity. ( Cha, Y; Chen, Z; Ding, H; Huang, X; Liu, J; Sheng, L; Wang, F; Wu, U; Xu, J, 2015) |
| "Berberine acts via multiple pathways to alleviate fibrosis in various tissues and shows renoprotective effects." | 4.31 | Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction. ( Gao, Z; Han, B; Hou, Y; Shi, H; Tan, E; Wang, L; Wang, Q; Zhu, G, 2023) |
| "The nephroprotective effects of berberine were mediated in part by downregulating P2X7R and modulating DUSP6-mediated inactivation of ERK1/2 as well as by suppressing SIRT2/MDM2-triggered renal fibrosis." | 4.12 | Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats. ( Ahmedy, OA; Al-Mokaddem, AK; El-Said, YAM; El-Tanbouly, DM, 2022) |
| "Berberine (BBR) is an active component of Phellodendri Cortex (PC), which is a traditional Chinese medicine that has been prescribed clinically for hyperuricemia (HUA) for hundreds of years." | 4.02 | Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model. ( Chen, J; Huang, Z; Li, Q; Li, Y; Liu, D; Su, Z; Xie, J; Zeng, H; Zheng, J, 2021) |
| "To investigate the potential effects of berberine on renal interstitial fibrosis (RIF) of obstructed kidneys in a unilateral ureteral obstruction (UUO) rat model." | 3.80 | Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats. ( He, YQ; Ma, LL; Tian, XJ; Wang, FM; Yang, YJ, 2014) |
| "Berberine is an isoquinoline derivative alkaloid with biological functions like antioxidant and anti-inflammatory." | 1.72 | Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice. ( Goudarzi, M; Kalantar, H; Kalantar, M; Khalili, H; Mombeini, MA; Sadeghi, E, 2022) |
| " However, BBR exhibits low bioavailability due to its extensive metabolism and limited absorption." | 1.62 | Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway. ( Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q, 2021) |
| " However, AA-containing herbs are highly safe in combination with berberine (Ber)-containing herbs in traditional medicine, suggesting the possible neutralizing effect of Ber on the toxicity of AA." | 1.62 | Berberine-Based Heterogeneous Linear Supramolecules Neutralized the Acute Nephrotoxicity of Aristolochic Acid by the Self-Assembly Strategy. ( Feng, Y; Guo, W; Huang, G; Huang, X; Lei, H; Li, T; Li, Y; Tian, X; Wang, P; Xu, A; Yuan, K; Zhao, L; Zhen, J, 2021) |
| "Berberine-treated rats significantly decreased urinary albumin excretion, a marker of renal injury (p < 0." | 1.42 | Effects of Berberine on Adipose Tissues and Kidney Function in 3T3-L1 Cells and Spontaneously Hypertensive Rats. ( Dong, SF; Ikeda, K; Kishimoto, A; Negishi, H; Sun, JN; Yasui, N, 2015) |
| "Berberine (BBR) has been reported in several studies in cell and animal models." | 1.42 | Protective effects of berberine on high fat-induced kidney damage by increasing serum adiponectin and promoting insulin sensitivity. ( Cha, Y; Chen, Z; Ding, H; Huang, X; Liu, J; Sheng, L; Wang, F; Wu, U; Xu, J, 2015) |
| "Treated with berberine for 4 weeks, elevated blood pressure and heightened levels of urine protein, blood urea nitrogen and serum creatinine in model rats were depressed significantly (P < 0." | 1.37 | [Effects and mechanism of berberine on the hypertensive renal injury rats induced by enriched high fat-salt-fructose diet]. ( Cai, Y; Li, HB; Lv, JH; Qi, CL, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 10 (58.82) | 2.80 |
| Authors | Studies |
|---|---|
| Avila-Carrasco, L | 1 |
| García-Mayorga, EA | 1 |
| Díaz-Avila, DL | 1 |
| Garza-Veloz, I | 1 |
| Martinez-Fierro, ML | 1 |
| González-Mateo, GT | 1 |
| Lin, G | 1 |
| Yu, Q | 1 |
| Xu, L | 1 |
| Huang, Z | 2 |
| Mai, L | 1 |
| Jiang, L | 1 |
| Su, Z | 2 |
| Xie, J | 2 |
| Li, Y | 3 |
| Liu, Y | 1 |
| Lin, Z | 1 |
| Chen, J | 2 |
| Mombeini, MA | 1 |
| Kalantar, H | 1 |
| Sadeghi, E | 1 |
| Goudarzi, M | 1 |
| Khalili, H | 1 |
| Kalantar, M | 1 |
| Ahmedy, OA | 1 |
| El-Tanbouly, DM | 1 |
| Al-Mokaddem, AK | 1 |
| El-Said, YAM | 1 |
| Alagal, RI | 1 |
| AlFaris, NA | 1 |
| Alshammari, GM | 1 |
| ALTamimi, JZ | 1 |
| AlMousa, LA | 1 |
| Yahya, MA | 1 |
| Tan, E | 1 |
| Gao, Z | 1 |
| Wang, Q | 1 |
| Han, B | 1 |
| Shi, H | 1 |
| Wang, L | 1 |
| Zhu, G | 1 |
| Hou, Y | 1 |
| Verma, VK | 1 |
| Malik, S | 1 |
| Mutneja, E | 1 |
| Sahu, AK | 1 |
| Rupashi, K | 1 |
| Dinda, AK | 1 |
| Arya, DS | 1 |
| Bhatia, J | 1 |
| Wang, P | 1 |
| Guo, W | 1 |
| Huang, G | 1 |
| Zhen, J | 1 |
| Li, T | 1 |
| Zhao, L | 1 |
| Yuan, K | 1 |
| Tian, X | 1 |
| Huang, X | 3 |
| Feng, Y | 1 |
| Lei, H | 1 |
| Xu, A | 1 |
| Li, Q | 1 |
| Liu, D | 1 |
| Zheng, J | 1 |
| Zeng, H | 1 |
| Ibrahim Fouad, G | 1 |
| Ahmed, KA | 1 |
| Su, G | 1 |
| Wang, H | 1 |
| Gao, Y | 1 |
| Chen, G | 1 |
| Pei, Y | 1 |
| Bai, J | 1 |
| Wu, Y | 1 |
| Yang, M | 1 |
| Xu, J | 2 |
| Chen, Z | 2 |
| Yu, Z | 1 |
| Liu, J | 2 |
| Wang, FM | 1 |
| Yang, YJ | 1 |
| Ma, LL | 1 |
| Tian, XJ | 1 |
| He, YQ | 1 |
| Kishimoto, A | 1 |
| Dong, SF | 1 |
| Negishi, H | 1 |
| Yasui, N | 1 |
| Sun, JN | 1 |
| Ikeda, K | 1 |
| Wu, U | 1 |
| Cha, Y | 1 |
| Wang, F | 1 |
| Sheng, L | 1 |
| Ding, H | 1 |
| Chen, X | 1 |
| Zhang, Y | 1 |
| Zhu, Z | 1 |
| Liu, H | 1 |
| Guo, H | 1 |
| Xiong, C | 1 |
| Xie, K | 1 |
| Zhang, X | 1 |
| Su, S | 1 |
| Li, HB | 1 |
| Cai, Y | 1 |
| Qi, CL | 1 |
| Lv, JH | 1 |
1 review available for berberine and Kidney Diseases
| Article | Year |
|---|---|
Potential Therapeutic Effects of Natural Plant Compounds in Kidney Disease.
Topics: Antioxidants; Berberine; Beta vulgaris; Betalains; Biological Products; Catechin; Curcumin; Disulfid | 2021 |
16 other studies available for berberine and Kidney Diseases
| Article | Year |
|---|---|
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Berberine; Blood Urea Nitrogen; Ch | 2021 |
Protective effects of berberine as a natural antioxidant and anti-inflammatory agent against nephrotoxicity induced by cyclophosphamide in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antioxidants; Berberine; Cyclo | 2022 |
Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats.
Topics: Actins; Animals; Berberine; Cisplatin; Dual Specificity Phosphatase 6; Fibrosis; Galectin 3; Kidney | 2022 |
The protection afforded by Berberine against chemotherapy-mediated nephropathy in rats involves regulation of the antioxidant axis.
Topics: Animals; Antioxidants; Berberine; Doxorubicin; Glutathione; Kelch-Like ECH-Associated Protein 1; Kid | 2023 |
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Fatty Acids; Fibrosis; Inflammasomes; Inflammatio | 2023 |
Mechanism Involved in Fortification by Berberine in CDDP-Induced Nephrotoxicity.
Topics: Animals; Apoptosis; Beclin-1; Berberine; Biomarkers; Cisplatin; Heme Oxygenase-1; Inflammation; Kidn | 2020 |
Berberine-Based Heterogeneous Linear Supramolecules Neutralized the Acute Nephrotoxicity of Aristolochic Acid by the Self-Assembly Strategy.
Topics: Animals; Aristolochic Acids; Berberine; Drug Interactions; Drugs, Chinese Herbal; Dysbiosis; Gastroi | 2021 |
Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model.
Topics: Animals; Berberine; Disease Models, Animal; Hyperuricemia; Kidney; Kidney Diseases; Male; Mice; Mole | 2021 |
The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats.
Topics: Animals; Apoptosis; Berberine; Biomarkers; Body Weight; Doxorubicin; Fibrillar Collagens; Inflammati | 2021 |
¹H-NMR-Based Metabonomics of the Protective Effect of Coptis chinensis and Berberine on Cinnabar-Induced Hepatotoxicity and Nephrotoxicity in Rats.
Topics: Animals; Berberine; Blood; Chemical and Drug Induced Liver Injury; Coptis; Kidney Diseases; Magnetic | 2017 |
Ameliorative effect of berberine coated bio-active nanoparticles in acetaminophen induced hepato-renal damage in diabetic rats.
Topics: Acetaminophen; Animals; Antioxidants; Berberine; Diabetes Mellitus, Experimental; Drug Carriers; Kid | 2018 |
Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats.
Topics: Actins; Animals; Berberine; Biomarkers; Catalase; Cytoprotection; Disease Models, Animal; Fibrosis; | 2014 |
Effects of Berberine on Adipose Tissues and Kidney Function in 3T3-L1 Cells and Spontaneously Hypertensive Rats.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Albuminuria; Animals; Berberine; Cell Differentiation; Gen | 2015 |
Protective effects of berberine on high fat-induced kidney damage by increasing serum adiponectin and promoting insulin sensitivity.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Berberine; Blood Glucose; C-Reactive Protein; C | 2015 |
Protective effect of berberine on doxorubicin‑induced acute hepatorenal toxicity in rats.
Topics: Animals; Berberine; Chemical and Drug Induced Liver Injury; Doxorubicin; Kidney Diseases; Male; Rats | 2016 |
[Effects and mechanism of berberine on the hypertensive renal injury rats induced by enriched high fat-salt-fructose diet].
Topics: Animals; Berberine; Blood Pressure; Body Weight; Creatinine; Diet; Diet, High-Fat; Disease Models, A | 2011 |