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berberine and Kernicterus

berberine has been researched along with Kernicterus in 1 studies

Kernicterus: A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)

Research Excerpts

ExcerptRelevanceReference
"A study was made of the effect of berberine, the major ingredient of the Chinese herb huanglian (coptis chinensis) reported to pose some risk for kernicterus among jaundiced newborn Chinese infants, on the protein binding of bilirubin, using the peroxidase kinetic method."3.68Displacement of bilirubin from albumin by berberine. ( Chan, E, 1993)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, E1

Other Studies

1 other study available for berberine and Kernicterus

ArticleYear
Displacement of bilirubin from albumin by berberine.
    Biology of the neonate, 1993, Volume: 63, Issue:4

    Topics: Animals; Berberine; Bilirubin; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; In

1993