berberine has been researched along with Invasiveness, Neoplasm in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was aimed to investigate the effect of berberine on cell migration and invasion in human retinoblastoma (Rb) cells." | 7.88 | Inhibition of migration and invasion by berberine via inactivation of PI3K/Akt and p38 in human retinoblastoma cell line. ( Chen, K; Gong, Y; Gui, M; Guo, X; Jin, Y; Ma, R; Wang, P; Wang, X; Wang, Y; Wu, Y; Yang, L; Yuan, J; Zhong, Y, 2018) |
| "The main purpose of this work was to investigate the effect of berberine hydrochloride (BH) on the proliferation, apoptosis, migration, and invasion of CNE-1 nasopharyngeal carcinoma cells." | 7.80 | Berberine hydrochloride impact on physiological processes and modulation of twist levels in nasopharyngeal carcinoma CNE-1 cells. ( Ding, H; Li, CH; Wu, DF; Xu, DF; Zhao, Y; Zhou, KY, 2014) |
| "Effects of coptisine on highly metastatic human breast cancer cell MDA-MB-231 proliferation were evaluated by trypan blue assay and on cell adhesion, migration and invasion by gelatin adhesion, wound-healing and matrigel invasion chamber assays, respectively." | 7.80 | Suppression of human breast cancer cell metastasis by coptisine in vitro. ( Cao, SP; Chen, SH; Li, J; Qiu, DM; Xia, XL, 2014) |
| "Berberine, a quaternary amine and isoquinoline alkaloid, has been proposed to have antimetastatic effects on many types of tumor cells; however, its exact inhibitory mechanisms with bladder cancer cells remain unclear." | 7.79 | Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase. ( Fan, Y; Gu, G; Jiao, W; Kun, W; Ma, Q; Tang, Y; Xu, L; Xu, Z; Yan, K; Yan, L, 2013) |
| " Here, we investigated the effect of the natural alkaloid berberine on As2O3-mediated inhibition of cancer cell migration using rat and human glioma cell lines." | 7.74 | Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide. ( Chou, FP; Kuo, HC; Lin, TH; Lu, FJ, 2008) |
| "We examined the effect of berberine, a major component with anti-fungal properties contained in Coptidis Rhizoma and Phellodendri Cortex, on the lymph node metastasis of murine lung cancer." | 7.71 | Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma. ( Ikeda, T; Mitani, N; Murakami, K; Saiki, I; Yamaura, T, 2001) |
| "Berberine (BBR) is a natural compound derived from some medicinal plants, and accumulating evidence has shown its potent anti-tumor activity with diverse action on tumor cells, including inducing cancer cell death and blocking cell cycle and migration." | 5.43 | Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. ( Cao, F; Feng, Y; Li, H; Liu, M; Tan, Y; Wang, N; Wang, X; Xiang, L; Yu, X; Zhang, J, 2016) |
| "Berberine could suppress the transcription level of Id-1 through inhibiting its promotor activity." | 5.42 | Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma. ( Cheung, KC; Cheung, YC; Feng, Y; Lui, VW; Man, K; Tsang, CM; Tsao, SW, 2015) |
| "Berberine can inhibit the oncogentic H-Ras and c-fos in T24 cells, and can induce the activation of the caspase-3 and caspase-9 apoptosis." | 5.37 | Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells. ( Fan, Y; Feng, J; Hou, L; Liu, C; Liu, Z; Xu, Z; Yan, K; Yan, L; Zhang, C; Zheng, B; Zhou, Z, 2011) |
| "This study was aimed to investigate the effect of berberine on cell migration and invasion in human retinoblastoma (Rb) cells." | 3.88 | Inhibition of migration and invasion by berberine via inactivation of PI3K/Akt and p38 in human retinoblastoma cell line. ( Chen, K; Gong, Y; Gui, M; Guo, X; Jin, Y; Ma, R; Wang, P; Wang, X; Wang, Y; Wu, Y; Yang, L; Yuan, J; Zhong, Y, 2018) |
| "The main purpose of this work was to investigate the effect of berberine hydrochloride (BH) on the proliferation, apoptosis, migration, and invasion of CNE-1 nasopharyngeal carcinoma cells." | 3.80 | Berberine hydrochloride impact on physiological processes and modulation of twist levels in nasopharyngeal carcinoma CNE-1 cells. ( Ding, H; Li, CH; Wu, DF; Xu, DF; Zhao, Y; Zhou, KY, 2014) |
| "Effects of coptisine on highly metastatic human breast cancer cell MDA-MB-231 proliferation were evaluated by trypan blue assay and on cell adhesion, migration and invasion by gelatin adhesion, wound-healing and matrigel invasion chamber assays, respectively." | 3.80 | Suppression of human breast cancer cell metastasis by coptisine in vitro. ( Cao, SP; Chen, SH; Li, J; Qiu, DM; Xia, XL, 2014) |
| "Berberine, a quaternary amine and isoquinoline alkaloid, has been proposed to have antimetastatic effects on many types of tumor cells; however, its exact inhibitory mechanisms with bladder cancer cells remain unclear." | 3.79 | Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase. ( Fan, Y; Gu, G; Jiao, W; Kun, W; Ma, Q; Tang, Y; Xu, L; Xu, Z; Yan, K; Yan, L, 2013) |
| " Here, we investigated the effect of the natural alkaloid berberine on As2O3-mediated inhibition of cancer cell migration using rat and human glioma cell lines." | 3.74 | Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide. ( Chou, FP; Kuo, HC; Lin, TH; Lu, FJ, 2008) |
| "We examined the effect of berberine, a major component with anti-fungal properties contained in Coptidis Rhizoma and Phellodendri Cortex, on the lymph node metastasis of murine lung cancer." | 3.71 | Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma. ( Ikeda, T; Mitani, N; Murakami, K; Saiki, I; Yamaura, T, 2001) |
| "Anti-metastasis mechanism of skin cancer by 13-butoxyberberine bromide, a novel berberine derivative, has not yet been reported." | 1.91 | 13-Butoxyberberine Bromide Inhibits Migration and Invasion in Skin Cancer A431 Cells. ( Laomethakorn, P; Samosorn, S; Tananyuthawongse, C; Tayeh, M; Watanapokasin, R, 2023) |
| "Gastric cancer is a prevalent malignant tumor that seriously affects human health." | 1.72 | Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6. ( Fan, J; Huang, L; Li, X; Ren, L; Xu, M; Ye, X; Zhou, L, 2022) |
| "The biological function of BBR in endometrial cancer (EC) and the underlying molecular mechanisms, however, remain unknown." | 1.48 | Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2. ( Wang, Y; Zhang, S, 2018) |
| "In endometriosis and endometrial cancer, LSR was observed not only in the subapical region but also throughout the lateral region as well as in normal endometrial epithelial cells in the secretory phase, and LSR in the cancer was reduced in correlation with the malignancy." | 1.43 | The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells. ( Hatakeyama, T; Kohno, T; Kojima, T; Konno, T; Saito, T; Satohisa, S; Shimada, H; Takahashi, S; Tsujiwaki, M, 2016) |
| "Berberine (BBR) is a natural compound derived from some medicinal plants, and accumulating evidence has shown its potent anti-tumor activity with diverse action on tumor cells, including inducing cancer cell death and blocking cell cycle and migration." | 1.43 | Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. ( Cao, F; Feng, Y; Li, H; Liu, M; Tan, Y; Wang, N; Wang, X; Xiang, L; Yu, X; Zhang, J, 2016) |
| "Berberine could suppress the transcription level of Id-1 through inhibiting its promotor activity." | 1.42 | Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma. ( Cheung, KC; Cheung, YC; Feng, Y; Lui, VW; Man, K; Tsang, CM; Tsao, SW, 2015) |
| "Berberine treatment also decreased various biochemical parameters associated with lung metastasis." | 1.38 | Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells. ( Hamsa, TP; Kuttan, G, 2012) |
| "Berberine- and AICAR-treated groups demonstrated significantly decreased lung metastases in the pulmonary metastasis model in vivo." | 1.38 | Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. ( Kim, EJ; Kim, HS; Kim, MJ; Lee, MS; Lim, JS; Yang, Y, 2012) |
| "Berberine can inhibit the oncogentic H-Ras and c-fos in T24 cells, and can induce the activation of the caspase-3 and caspase-9 apoptosis." | 1.37 | Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells. ( Fan, Y; Feng, J; Hou, L; Liu, C; Liu, Z; Xu, Z; Yan, K; Yan, L; Zhang, C; Zheng, B; Zhou, Z, 2011) |
| "Berberine is an active ingredient extracted from Coptidis rhizoma which has been used for centuries as a traditional Chinese medicine for treatment of inflammatory diseases." | 1.35 | Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells. ( Cheung, AL; Cheung, PY; Ching, YP; Di, K; Feng, Y; Hau, PM; Lau, EP; Tong, Y; Tsang, CM; Tsao, SW; Wan, TS; Wong, YC, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 16 (61.54) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, M | 1 |
| Ren, L | 1 |
| Fan, J | 1 |
| Huang, L | 1 |
| Zhou, L | 2 |
| Li, X | 1 |
| Ye, X | 1 |
| Laomethakorn, P | 1 |
| Tayeh, M | 1 |
| Samosorn, S | 1 |
| Tananyuthawongse, C | 1 |
| Watanapokasin, R | 1 |
| Zheng, F | 1 |
| Wu, J | 1 |
| Tang, Q | 1 |
| Xiao, Q | 1 |
| Wu, W | 1 |
| Hann, SS | 1 |
| Wang, Y | 2 |
| Yuan, J | 1 |
| Yang, L | 1 |
| Wang, P | 1 |
| Wang, X | 2 |
| Wu, Y | 1 |
| Chen, K | 1 |
| Ma, R | 1 |
| Zhong, Y | 1 |
| Guo, X | 1 |
| Gong, Y | 1 |
| Gui, M | 1 |
| Jin, Y | 1 |
| Zhang, S | 1 |
| Qi, HW | 1 |
| Xin, LY | 1 |
| Xu, X | 1 |
| Ji, XX | 1 |
| Fan, LH | 1 |
| Yu, D | 1 |
| Fu, S | 1 |
| Cao, Z | 1 |
| Bao, M | 1 |
| Zhang, G | 1 |
| Pan, Y | 1 |
| Liu, W | 1 |
| Zhou, Q | 1 |
| Li, CH | 1 |
| Wu, DF | 1 |
| Ding, H | 1 |
| Zhao, Y | 1 |
| Zhou, KY | 1 |
| Xu, DF | 1 |
| Li, J | 1 |
| Qiu, DM | 1 |
| Chen, SH | 1 |
| Cao, SP | 1 |
| Xia, XL | 1 |
| Tsang, CM | 2 |
| Cheung, KC | 1 |
| Cheung, YC | 1 |
| Man, K | 1 |
| Lui, VW | 1 |
| Tsao, SW | 2 |
| Feng, Y | 3 |
| Liu, X | 1 |
| Ji, Q | 1 |
| Ye, N | 1 |
| Sui, H | 1 |
| Zhu, H | 1 |
| Fan, Z | 1 |
| Cai, J | 1 |
| Li, Q | 1 |
| Shimada, H | 1 |
| Satohisa, S | 1 |
| Kohno, T | 1 |
| Takahashi, S | 1 |
| Hatakeyama, T | 1 |
| Konno, T | 1 |
| Tsujiwaki, M | 1 |
| Saito, T | 1 |
| Kojima, T | 1 |
| Wang, N | 1 |
| Li, H | 1 |
| Liu, M | 1 |
| Cao, F | 1 |
| Yu, X | 1 |
| Zhang, J | 1 |
| Tan, Y | 1 |
| Xiang, L | 1 |
| Pandey, MK | 1 |
| Sung, B | 1 |
| Kunnumakkara, AB | 1 |
| Sethi, G | 1 |
| Chaturvedi, MM | 1 |
| Aggarwal, BB | 1 |
| Ho, YT | 1 |
| Yang, JS | 1 |
| Li, TC | 1 |
| Lin, JJ | 1 |
| Lin, JG | 1 |
| Lai, KC | 1 |
| Ma, CY | 1 |
| Wood, WG | 1 |
| Chung, JG | 1 |
| Lau, EP | 1 |
| Di, K | 1 |
| Cheung, PY | 1 |
| Hau, PM | 1 |
| Ching, YP | 1 |
| Wong, YC | 1 |
| Cheung, AL | 1 |
| Wan, TS | 1 |
| Tong, Y | 1 |
| Yan, K | 2 |
| Zhang, C | 1 |
| Feng, J | 1 |
| Hou, L | 1 |
| Yan, L | 2 |
| Zhou, Z | 1 |
| Liu, Z | 1 |
| Liu, C | 1 |
| Fan, Y | 2 |
| Zheng, B | 1 |
| Xu, Z | 2 |
| Huang, D | 1 |
| Wang, W | 1 |
| Feng, Z | 1 |
| Wang, L | 1 |
| Chen, Y | 1 |
| Xie, C | 1 |
| Meng, J | 1 |
| Tang, F | 1 |
| Hamsa, TP | 1 |
| Kuttan, G | 1 |
| Kim, HS | 1 |
| Kim, MJ | 1 |
| Kim, EJ | 1 |
| Yang, Y | 1 |
| Lee, MS | 1 |
| Lim, JS | 1 |
| Kun, W | 1 |
| Xu, L | 1 |
| Ma, Q | 1 |
| Tang, Y | 1 |
| Jiao, W | 1 |
| Gu, G | 1 |
| Saiki, I | 2 |
| Peng, PL | 1 |
| Hsieh, YS | 1 |
| Wang, CJ | 1 |
| Hsu, JL | 1 |
| Chou, FP | 2 |
| Liu, SJ | 1 |
| Sun, YM | 1 |
| Tian, DF | 1 |
| He, YC | 1 |
| Zeng, L | 1 |
| He, Y | 1 |
| Ling, CQ | 1 |
| Sun, SH | 1 |
| Lin, TH | 1 |
| Kuo, HC | 1 |
| Lu, FJ | 1 |
| Mitani, N | 1 |
| Murakami, K | 1 |
| Yamaura, T | 1 |
| Ikeda, T | 1 |
26 other studies available for berberine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Topics: Animals; Apoptosis; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; China; Gene Expr | 2022 |
13-Butoxyberberine Bromide Inhibits Migration and Invasion in Skin Cancer A431 Cells.
Topics: Berberine; Bromides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Neoplasm Invasiven | 2023 |
The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Berberine; Cell Cycle Checkpoints; Cell Line, Tumor; C | 2018 |
Inhibition of migration and invasion by berberine via inactivation of PI3K/Akt and p38 in human retinoblastoma cell line.
Topics: Berberine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Huma | 2018 |
Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2.
Topics: Animals; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygena | 2018 |
Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis.
Topics: Animals; Apoptosis; Berberine; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferatio | 2014 |
Unraveling the novel anti-osteosarcoma function of coptisine and its mechanisms.
Topics: Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; Berberine; Bone Neoplasms; Cadherins; Cell | 2014 |
Berberine hydrochloride impact on physiological processes and modulation of twist levels in nasopharyngeal carcinoma CNE-1 cells.
Topics: Annexin A5; Apoptosis; Berberine; Carcinoma; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Prolif | 2014 |
Suppression of human breast cancer cell metastasis by coptisine in vitro.
Topics: Berberine; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Col | 2014 |
Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma.
Topics: Animals; Berberine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Gene Expression | 2015 |
Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cell Movement; Colon; Color | 2015 |
The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.
Topics: Adiponectin; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Endome | 2016 |
Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine.
Topics: Anti-Inflammatory Agents; Berberine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Dow | 2016 |
Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Berberine; | 2008 |
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9.
Topics: Antineoplastic Agents; Berberine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Down-Re | 2009 |
Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Do | 2009 |
Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Berberine; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferat | 2011 |
Berberine inhibits the invasion and metastasis of nasopharyngeal carcinoma cells through Ezrin phosphorylation.
Topics: Antineoplastic Agents, Phytogenic; Berberine; Cell Line, Tumor; Cytoskeletal Proteins; Humans; Nasop | 2011 |
Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells.
Topics: Activating Transcription Factor 2; Animals; Antineoplastic Agents, Phytogenic; Berberine; Cell Line, | 2012 |
Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Cell Line, Tumor; Cyclooxygenase 2; Enzyme Activa | 2012 |
Berberine inhibits the migration and invasion of T24 bladder cancer cells via reducing the expression of heparanase.
Topics: Antineoplastic Agents; Berberine; Cell Line, Tumor; Cell Movement; Glucuronidase; Humans; Neoplasm I | 2013 |
[Screening for inhibitors of tumor invasion into basement membranes].
Topics: Animals; Basement Membrane; Berberine; Camptothecin; Carcinoma, Lewis Lung; Cell Movement; Drug Scre | 2004 |
Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Topics: Antineoplastic Agents, Phytogenic; Berberine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell | 2006 |
Downregulated NM23-H1 expression is associated with intracranial invasion of nasopharyngeal carcinoma.
Topics: Adult; Animals; Antineoplastic Agents; Berberine; Brain Neoplasms; Carcinoma; Down-Regulation; Drug | 2008 |
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide.
Topics: Actins; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Berberine; Cell Line, Tumor; C | 2008 |
Inhibitory effect of berberine on the mediastinal lymph node metastasis produced by orthotopic implantation of Lewis lung carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Berberine; Camptothecin; Carcinoma, Lewis L | 2001 |