berberine has been researched along with Hypoxia in 18 studies
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, hypoxia-reoxygenation (H/R)-treated L02 cells were pretreated with berberine to study the role and mechanism of berberine in resisting hepatic ischemia-reperfusion injury." | 8.31 | Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2. ( Li, C; Li, J; Liu, H; Ming, Y; Peng, B; Zhang, P; Zhu, Y, 2023) |
| " Ischemia-related damage was induced by OGD (5, 15, 45 min) or NMDA (10 microM) treatment, and was evaluated by measuring propidium iodide (PI) uptake." | 7.75 | Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression. ( Cui, HS; Hori, H; Matsumoto, K; Murakami, Y; Obi, R; Zhao, Q, 2009) |
| "Berberine is an alkaloid derived from herb the Berberis sp." | 5.40 | Berberine was neuroprotective against an in vitro model of brain ischemia: survival and apoptosis pathways involved. ( Frozza, RL; Hoppe, JB; Menezes, Bde M; Salbego, CG; Simões Pires, EN, 2014) |
| "In this study, hypoxia-reoxygenation (H/R)-treated L02 cells were pretreated with berberine to study the role and mechanism of berberine in resisting hepatic ischemia-reperfusion injury." | 4.31 | Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2. ( Li, C; Li, J; Liu, H; Ming, Y; Peng, B; Zhang, P; Zhu, Y, 2023) |
| "Male ICR mice were divided into 5 groups: control group, hypoxia group, hypoxia group treated with nifedipine (10 mg/kg), hypoxia groups treated with CPU86017-RS (60 or 80 mg/kg)." | 3.78 | CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines. ( Cheng, YS; Dai, DZ; Dai, Y; Yu, F; Zhang, C; Zhang, GL, 2012) |
| "To investigate the protection of pulmonary arterial rings and cardiac myocytes of rats by raisanberine (RS), a derivative of berberine, against hypoxia injury and to elucidate the action mechanisms." | 3.78 | Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx. ( Cheng, YS; Dai, DZ; Dai, Y; Gao, J; Tang, YQ; Zhang, C; Zhang, GL, 2012) |
| " Ischemia-related damage was induced by OGD (5, 15, 45 min) or NMDA (10 microM) treatment, and was evaluated by measuring propidium iodide (PI) uptake." | 3.75 | Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression. ( Cui, HS; Hori, H; Matsumoto, K; Murakami, Y; Obi, R; Zhao, Q, 2009) |
| "Remodeling of the pulmonary artery is a major feature of pulmonary artery hypertension, and CPU86017, a derivative of berberine, is known to effectively alleviate hypoxic pulmonary hypertension (HPH)." | 3.74 | CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation. ( Dai, DZ; Dai, Y; Li, N, 2008) |
| "To investigate the protective mechanism of geniposide, baicalin and berberine on hypoxia and reoxygenation injury in cultured rat cerebral microvascular endothelial cells." | 3.74 | [Effect of effective components of huanglian jiedu decoction on hypoxia, reoxygenation injury and the expression of VCAM in cultured rat cerebral microvascular endothelial cells]. ( Gao, YH; Niu, FL; Pang, H; Shan, ZS; Wang, SR; Yuan, ZZ; Zhu, LQ, 2008) |
| " The present study was conducted to examine the effects of a novel compound p-chlorobenzyltetrahydroberberine (CPU 86017) on endothelin-1 system of hypoxia-induced pulmonary hypertension in rats." | 3.73 | Pharmacological efficacy of CPU 86017 on hypoxic pulmonary hypertension in rats: mediated by direct inhibition of calcium channels and antioxidant action, but indirect effects on the ET-1 pathway. ( Cui, B; Dai, DZ; Tang, XY; Zhang, TT, 2005) |
| "Berberine is an alkaloid derived from herb the Berberis sp." | 1.40 | Berberine was neuroprotective against an in vitro model of brain ischemia: survival and apoptosis pathways involved. ( Frozza, RL; Hoppe, JB; Menezes, Bde M; Salbego, CG; Simões Pires, EN, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Z | 1 |
| Dong, Q | 1 |
| Guan, R | 1 |
| Sun, Y | 2 |
| Liu, X | 1 |
| Zou, Y | 1 |
| Xia, QS | 1 |
| Wu, F | 1 |
| Wu, WB | 1 |
| Dong, H | 1 |
| Huang, ZY | 1 |
| Xu, L | 1 |
| Lu, FE | 1 |
| Gong, J | 1 |
| Zhou, Q | 1 |
| Chen, F | 1 |
| Gao, X | 1 |
| Yang, L | 1 |
| Jin, X | 1 |
| Wink, M | 1 |
| Sharopov, FS | 1 |
| Sethi, G | 1 |
| Zhu, Y | 1 |
| Li, J | 1 |
| Zhang, P | 1 |
| Peng, B | 1 |
| Li, C | 1 |
| Ming, Y | 1 |
| Liu, H | 1 |
| Yue, M | 1 |
| Tao, Y | 1 |
| Fang, Y | 1 |
| Lian, X | 1 |
| Zhang, Q | 1 |
| Xia, Y | 1 |
| Wei, Z | 1 |
| Dai, Y | 5 |
| Wang, Y | 1 |
| Wang, Q | 1 |
| Zhang, L | 1 |
| Ke, Z | 1 |
| Zhao, Y | 1 |
| Wang, D | 1 |
| Chen, H | 1 |
| Jiang, X | 1 |
| Gu, M | 1 |
| Fan, S | 1 |
| Huang, C | 1 |
| Sreeja, S | 1 |
| Krishnan Nair, CK | 1 |
| Chen, M | 1 |
| Shen, H | 1 |
| Zhu, L | 1 |
| Yang, H | 1 |
| Ye, P | 1 |
| Liu, P | 1 |
| Gu, Y | 1 |
| Chen, S | 1 |
| Simões Pires, EN | 1 |
| Frozza, RL | 1 |
| Hoppe, JB | 1 |
| Menezes, Bde M | 1 |
| Salbego, CG | 1 |
| Li, N | 1 |
| Dai, DZ | 5 |
| Cui, HS | 1 |
| Matsumoto, K | 1 |
| Murakami, Y | 1 |
| Hori, H | 1 |
| Zhao, Q | 1 |
| Obi, R | 1 |
| Yuan, ZZ | 1 |
| Zhu, LQ | 1 |
| Pang, H | 1 |
| Shan, ZS | 1 |
| Wang, SR | 1 |
| Gao, YH | 1 |
| Niu, FL | 1 |
| Liu, GL | 1 |
| Yu, F | 2 |
| Zhang, GL | 3 |
| Zhang, C | 3 |
| Cheng, YS | 2 |
| Gao, J | 1 |
| Tang, YQ | 1 |
| Zhang, TT | 1 |
| Cui, B | 1 |
| Tang, XY | 1 |
| Wang, YX | 1 |
| Yao, XJ | 1 |
| Tan, YH | 1 |
| Xu, LY | 1 |
| Li, YK | 1 |
| Cai, ZZ | 1 |
| Zhou, H | 1 |
| Feng, Y | 1 |
18 other studies available for berberine and Hypoxia
| Article | Year |
|---|---|
[Berberine hydrochloride attenuates liver injury induced by acute hypoxic exposure by inhibiting TNF-α/caspase-8/caspase-3 signaling pathway].
Topics: Animals; Berberine; Caspase 3; Caspase 8; Hypoxia; Liver; Mice; Mice, Inbred C57BL; Signal Transduct | 2022 |
Berberine reduces hepatic ceramide levels to improve insulin resistance in HFD-fed mice by inhibiting HIF-2α.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Berberine; Ceramides; Diabetes Mellitus, Type | 2022 |
Berberine inhibits breast carcinoma proliferation and metastasis under hypoxic microenvironment involving gut microbiota and endogenous metabolites.
Topics: Animals; Berberine; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Gast | 2023 |
Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2.
Topics: Berberine; Cytokines; Hepatocytes; Humans; Hypoxia; Reperfusion Injury | 2023 |
The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Berberine; Butyrates; Female; Gastrointesti | 2019 |
Coptisine protects cardiomyocyte against hypoxia/reoxygenation-induced damage via inhibition of autophagy.
Topics: Animals; Apoptosis; Berberine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hyp | 2017 |
Tumor control by hypoxia-specific chemotargeting of iron-oxide nanoparticle - Berberine complexes in a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Berberine; Biomarkers, Tumor; DNA, Neoplas | 2018 |
Berberine attenuates hypoxia-induced pulmonary arterial hypertension via bone morphogenetic protein and transforming growth factor-β signaling.
Topics: Animals; Berberine; Bone Morphogenetic Protein Receptors, Type II; Bone Morphogenetic Proteins; Cell | 2019 |
Berberine was neuroprotective against an in vitro model of brain ischemia: survival and apoptosis pathways involved.
Topics: Animals; Apoptosis; Berberine; Brain Ischemia; Caspase 3; Cell Survival; Disease Models, Animal; Dos | 2014 |
CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation.
Topics: Animals; Berberine; Extracellular Matrix; Gene Expression Regulation; Hypertension, Pulmonary; Hypox | 2008 |
Berberine exerts neuroprotective actions against in vitro ischemia-induced neuronal cell damage in organotypic hippocampal slice cultures: involvement of B-cell lymphoma 2 phosphorylation suppression.
Topics: Animals; Berberine; Cell Death; Docosahexaenoic Acids; Excitatory Amino Acid Agonists; Glucose; Hipp | 2009 |
[Effect of effective components of huanglian jiedu decoction on hypoxia, reoxygenation injury and the expression of VCAM in cultured rat cerebral microvascular endothelial cells].
Topics: Animals; Berberine; Cell Hypoxia; Cells, Cultured; Cerebrum; Drugs, Chinese Herbal; Endothelium, Vas | 2008 |
Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Berberine; Calcium; Calcium Channel Blockers; Down-Regulat | 2012 |
CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines.
Topics: 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Berberine; Calcium Channel Blockers; Connexin 4 | 2012 |
Raisanberine protected pulmonary arterial rings and cardiac myocytes of rats against hypoxia injury by suppressing NADPH oxidase and calcium influx.
Topics: Administration, Oral; Animals; Antioxidants; Arterioles; Berberine; Calcium Channel Blockers; Calciu | 2012 |
Pharmacological efficacy of CPU 86017 on hypoxic pulmonary hypertension in rats: mediated by direct inhibition of calcium channels and antioxidant action, but indirect effects on the ET-1 pathway.
Topics: Animals; Antioxidants; Berberine; Calcium Channel Blockers; Calcium Channels, L-Type; Endothelin-1; | 2005 |
Effects of berberine on delayed afterdepolarizations in ventricular muscles in vitro and in vivo.
Topics: Animals; Anti-Arrhythmia Agents; Berberine; Calcium Gluconate; Electrophysiology; Female; Guinea Pig | 1994 |
[Chemical components and pharmacological effects of Chinese herbal drugs after radio-sterilization].
Topics: Animals; Berberine; Cobalt Radioisotopes; Drugs, Chinese Herbal; Female; Ginsenosides; Hypoxia; Mice | 1987 |