berberine has been researched along with Frontotemporal Lobar Degeneration in 1 studies
Frontotemporal Lobar Degeneration: Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we studied the molecular mechanism of berberine in cell culture model with TDP-43 proteinopathies, and found that berberine is able to reverse the processing of insoluble TDP-43 aggregates formation through deregulation of mTOR/p70S6K signal and activation of autophagic degradation pathway." | 3.83 | Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS. ( Chang, CF; Chen, CL; Huang, CC; Lee, KH; Lee, YC; Lin, HC; Shen, CJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CF | 1 |
| Lee, YC | 1 |
| Lee, KH | 1 |
| Lin, HC | 1 |
| Chen, CL | 1 |
| Shen, CJ | 1 |
| Huang, CC | 1 |
1 other study available for berberine and Frontotemporal Lobar Degeneration
| Article | Year |
|---|---|
Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Berberine; Cell Line, Tumor; Frontotemporal Lobar Degenerati | 2016 |