berberine has been researched along with Fibrosis in 28 studies
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Berberine acts via multiple pathways to alleviate fibrosis in various tissues and shows renoprotective effects." | 8.31 | Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction. ( Gao, Z; Han, B; Hou, Y; Shi, H; Tan, E; Wang, L; Wang, Q; Zhu, G, 2023) |
| "To evaluate the effect of berberine (BBR) in preventing the development of epidural fibrosis (EF) after lumbar surgery in rats." | 8.12 | Evaluation of the effects of berberine in the prevention of epidural fibrosis in rats: An experimental research. ( Işık, E; Kaya, M; Keskin, E; Tönge, Ç, 2022) |
| "The nephroprotective effects of berberine were mediated in part by downregulating P2X7R and modulating DUSP6-mediated inactivation of ERK1/2 as well as by suppressing SIRT2/MDM2-triggered renal fibrosis." | 8.12 | Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats. ( Ahmedy, OA; Al-Mokaddem, AK; El-Said, YAM; El-Tanbouly, DM, 2022) |
| "This study was designed to investigate the molecular mechanisms underlying the anti-inflammatory and anti-fibrosis effects of Berberine hydrochloride (BBR) following canalicular laceration (CL) surgical repair." | 7.96 | Berberine hydrochloride inhibits inflammation and fibrosis after canalicular laceration repair in rabbits. ( Bai, F; Huang, Y; Liu, C; Tao, H; Wang, F; Wang, L; Wang, P; Zhou, X, 2020) |
| "Objective To explore the effect of berberine on cardiac fibrosis of diabetic rats by observing the expressions of serum transforming growth factor-β1 (TGF-β1), connective tissue growth factor (CTGF) , collagen type 1 (Col1) and collagen type 3 (Col3) in myocardial tissues of diabetic rats after berberine treatment." | 7.83 | [Berberine inhibits cardiac fibrosis of diabetic rats]. ( He, J; Liu, G; Lu, K; Shen, Y; Song, W, 2016) |
| "To investigate the potential effects of berberine on renal interstitial fibrosis (RIF) of obstructed kidneys in a unilateral ureteral obstruction (UUO) rat model." | 7.80 | Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats. ( He, YQ; Ma, LL; Tian, XJ; Wang, FM; Yang, YJ, 2014) |
| "Berberine (BR) acts as an AMP-activated protein kinase (AMPK) activator which possesses antioxidant and anti-inflammatory properties." | 5.56 | Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization. ( Bansod, S; Doijad, N; Godugu, C, 2020) |
| "Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function." | 5.51 | Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats. ( Che, Y; Jin, YG; Shen, DF; Wang, SS; Wang, ZP; Wu, QQ; Yuan, Y, 2019) |
| "Berberine (BBR) has been shown to relieve several metabolic disorders, including obesity and type 2 diabetes." | 5.48 | Berberine alleviates adipose tissue fibrosis by inducing AMP-activated kinase signaling in high-fat diet-induced obese mice. ( Hua, Y; Song, Y; Wang, L; Ye, X, 2018) |
| "Berberine (BBR) is a material extracted from Chinese herbs, which has been used in the treatment of diabetes in Chinese medicine for thousands of years." | 5.46 | Protective effect of berberine on renal fibrosis caused by diabetic nephropathy. ( Li, Z; Zhang, W, 2017) |
| "Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also an important risk for developing heart failure." | 5.40 | Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. ( Chen, SL; Iqbal, J; Li, B; Li, MH; Mao, WX; Mi, QY; Wang, ZM; Xie, HG; Yang, SH; Yu, YH; Zhang, YJ, 2014) |
| "Berberine acts via multiple pathways to alleviate fibrosis in various tissues and shows renoprotective effects." | 4.31 | Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction. ( Gao, Z; Han, B; Hou, Y; Shi, H; Tan, E; Wang, L; Wang, Q; Zhu, G, 2023) |
| "To evaluate the effect of berberine (BBR) in preventing the development of epidural fibrosis (EF) after lumbar surgery in rats." | 4.12 | Evaluation of the effects of berberine in the prevention of epidural fibrosis in rats: An experimental research. ( Işık, E; Kaya, M; Keskin, E; Tönge, Ç, 2022) |
| "Berberine (BBR), an alkaloid produced by a traditional Chinese plant, was recently attributed multiple effects on lipometabolism, inflammation, and fibrosis." | 4.12 | Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts. ( Chen, X; Diao, J; Ma, X; Mou, P; Wei, R, 2022) |
| "The nephroprotective effects of berberine were mediated in part by downregulating P2X7R and modulating DUSP6-mediated inactivation of ERK1/2 as well as by suppressing SIRT2/MDM2-triggered renal fibrosis." | 4.12 | Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats. ( Ahmedy, OA; Al-Mokaddem, AK; El-Said, YAM; El-Tanbouly, DM, 2022) |
| "Compared with the sham group, rats of the TAC group showed significantly increased cardiac hypertrophy and fibrosis, which could be ameliorated by treatment with berberine." | 3.96 | Berberine Attenuates Cardiac Hypertrophy Through Inhibition of mTOR Signaling Pathway. ( Chen, J; Chen, X; Cheng, C; Huang, S; Jiang, X; Liu, S; Xu, M, 2020) |
| "This study was designed to investigate the molecular mechanisms underlying the anti-inflammatory and anti-fibrosis effects of Berberine hydrochloride (BBR) following canalicular laceration (CL) surgical repair." | 3.96 | Berberine hydrochloride inhibits inflammation and fibrosis after canalicular laceration repair in rabbits. ( Bai, F; Huang, Y; Liu, C; Tao, H; Wang, F; Wang, L; Wang, P; Zhou, X, 2020) |
| "Objective To explore the effect of berberine on cardiac fibrosis of diabetic rats by observing the expressions of serum transforming growth factor-β1 (TGF-β1), connective tissue growth factor (CTGF) , collagen type 1 (Col1) and collagen type 3 (Col3) in myocardial tissues of diabetic rats after berberine treatment." | 3.83 | [Berberine inhibits cardiac fibrosis of diabetic rats]. ( He, J; Liu, G; Lu, K; Shen, Y; Song, W, 2016) |
| "The effects of berberine, dihydroberberine, canadine, stylopine, and coptisine were investigated on an in vitro model of fibrosis purposely set up." | 3.81 | In vitro studies of antifibrotic and cytoprotective effects elicited by proto-berberine alkaloids in human dermal fibroblasts. ( Bianucci, AM; Borghini, A; Pietra, D, 2015) |
| "To investigate the potential effects of berberine on renal interstitial fibrosis (RIF) of obstructed kidneys in a unilateral ureteral obstruction (UUO) rat model." | 3.80 | Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats. ( He, YQ; Ma, LL; Tian, XJ; Wang, FM; Yang, YJ, 2014) |
| "Fibrosis is a general term encompassing a plethora of pathologies that span all systems and is marked by increased deposition of collagen." | 2.53 | AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. ( Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S, 2016) |
| " Thus increasing the oral bioavailability of Pgp substrate-like drugs (PSLDs) remains a great challenge." | 1.62 | Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs. ( Chen, QL; Chu, JMT; Hu, YJ; Li, J; Linghu, KG; Wang, YT; Wong, GTC; Xiong, SH; Xiong, W; Yu, H; Zhao, GD, 2021) |
| "Berberine (BR) acts as an AMP-activated protein kinase (AMPK) activator which possesses antioxidant and anti-inflammatory properties." | 1.56 | Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization. ( Bansod, S; Doijad, N; Godugu, C, 2020) |
| "Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function." | 1.51 | Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats. ( Che, Y; Jin, YG; Shen, DF; Wang, SS; Wang, ZP; Wu, QQ; Yuan, Y, 2019) |
| "Berberine (BBR) has been shown to relieve several metabolic disorders, including obesity and type 2 diabetes." | 1.48 | Berberine alleviates adipose tissue fibrosis by inducing AMP-activated kinase signaling in high-fat diet-induced obese mice. ( Hua, Y; Song, Y; Wang, L; Ye, X, 2018) |
| "Berberine (BBR) is a material extracted from Chinese herbs, which has been used in the treatment of diabetes in Chinese medicine for thousands of years." | 1.46 | Protective effect of berberine on renal fibrosis caused by diabetic nephropathy. ( Li, Z; Zhang, W, 2017) |
| "Berberine has proven protective effects on diabetic nephropathy, but the mechanism for its effects has not been comprehensively established." | 1.42 | Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats. ( Ding, HH; Ni, WJ; Qiu, YY; Tang, LQ; Zhou, H, 2015) |
| "Berberine treatment of palmitate-incubated H9c2 cells reduced hypertrophy, increased α-MHC expression and decreased β-MHC expression." | 1.42 | Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells. ( Chang, W; Chen, L; Hatch, GM; Meng, Z; Yao, F; Yu, Y; Zhang, M, 2015) |
| "Cardiac hypertrophy is a maladaptive change in response to pressure overload, and is also an important risk for developing heart failure." | 1.40 | Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. ( Chen, SL; Iqbal, J; Li, B; Li, MH; Mao, WX; Mi, QY; Wang, ZM; Xie, HG; Yang, SH; Yu, YH; Zhang, YJ, 2014) |
| "Rats with renal artery stenosis were randomly assigned to two groups (n = 6 each) - ARD, or ARD+BBR - according to diet alone or in combination with BBR." | 1.39 | Berberine ameliorates chronic kidney injury caused by atherosclerotic renovascular disease through the suppression of NFκB signaling pathway in rats. ( Cao, CC; Chen, W; Chen, X; Huang, WJ; Liu, L; Miao, GG; Wan, X; Xie, HG; Zhang, Q; Zhao, Y, 2013) |
| "One of the main pathological changes in diabetic nephropathy is the renal fibrosis, which includes glomerulosclerosis and tubulointerstitial fibrosis." | 1.36 | Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury. ( Huang, H; Jiang, Q; Lan, T; Li, W; Liu, P; Liu, W; Shen, X; Xie, X; Zhang, X, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (53.57) | 24.3611 |
| 2020's | 13 (46.43) | 2.80 |
| Authors | Studies |
|---|---|
| Keskin, E | 1 |
| Tönge, Ç | 1 |
| Kaya, M | 1 |
| Işık, E | 1 |
| Ma, Z | 1 |
| Zhu, L | 1 |
| Wang, S | 1 |
| Guo, X | 1 |
| Sun, B | 1 |
| Wang, Q | 2 |
| Chen, L | 2 |
| Diao, J | 1 |
| Chen, X | 3 |
| Mou, P | 1 |
| Ma, X | 1 |
| Wei, R | 1 |
| Ahmedy, OA | 1 |
| El-Tanbouly, DM | 1 |
| Al-Mokaddem, AK | 1 |
| El-Said, YAM | 1 |
| Wang, Y | 1 |
| Liao, J | 1 |
| Luo, Y | 1 |
| Li, M | 1 |
| Su, X | 1 |
| Yu, B | 1 |
| Teng, J | 1 |
| Wang, H | 1 |
| Lv, X | 1 |
| Tan, E | 1 |
| Gao, Z | 1 |
| Han, B | 1 |
| Shi, H | 1 |
| Wang, L | 3 |
| Zhu, G | 1 |
| Hou, Y | 1 |
| Che, Y | 1 |
| Shen, DF | 1 |
| Wang, ZP | 1 |
| Jin, YG | 1 |
| Wu, QQ | 1 |
| Wang, SS | 1 |
| Yuan, Y | 1 |
| Ciszewski, L | 1 |
| Lu-Nguyen, N | 1 |
| Slater, A | 1 |
| Brennan, A | 1 |
| Williams, HEL | 1 |
| Dickson, G | 1 |
| Searle, MS | 1 |
| Popplewell, L | 1 |
| Jiang, X | 1 |
| Cheng, C | 1 |
| Chen, J | 1 |
| Huang, S | 1 |
| Xu, M | 1 |
| Liu, S | 1 |
| Bansod, S | 1 |
| Doijad, N | 1 |
| Godugu, C | 1 |
| Bai, F | 1 |
| Tao, H | 1 |
| Wang, P | 1 |
| Zhou, X | 1 |
| Wang, F | 1 |
| Liu, C | 1 |
| Huang, Y | 1 |
| Xiao, Y | 1 |
| Deng, J | 1 |
| Li, C | 1 |
| Gong, X | 1 |
| Gui, Z | 1 |
| Huang, J | 2 |
| Zhang, Y | 1 |
| Liu, Y | 1 |
| Ye, X | 2 |
| Li, X | 1 |
| Rajabi, S | 1 |
| Najafipour, H | 1 |
| Jafarinejad-Farsangi, S | 1 |
| Joukar, S | 1 |
| Beik, A | 1 |
| Askaripour, M | 1 |
| Jafari, E | 1 |
| Safi, Z | 1 |
| Xiong, W | 1 |
| Xiong, SH | 1 |
| Chen, QL | 1 |
| Linghu, KG | 1 |
| Zhao, GD | 1 |
| Chu, JMT | 1 |
| Wong, GTC | 1 |
| Li, J | 3 |
| Hu, YJ | 1 |
| Wang, YT | 1 |
| Yu, H | 1 |
| Li, Z | 1 |
| Zhang, W | 1 |
| Hua, Y | 1 |
| Song, Y | 1 |
| Li, G | 1 |
| Xing, W | 1 |
| Zhang, M | 2 |
| Geng, F | 1 |
| Yang, H | 1 |
| Zhang, H | 1 |
| Zhang, X | 3 |
| Dong, L | 1 |
| Gao, F | 1 |
| Wan, X | 1 |
| Liu, L | 1 |
| Zhao, Y | 1 |
| Huang, WJ | 1 |
| Zhang, Q | 1 |
| Miao, GG | 1 |
| Chen, W | 1 |
| Xie, HG | 2 |
| Cao, CC | 1 |
| Li, MH | 1 |
| Zhang, YJ | 1 |
| Yu, YH | 1 |
| Yang, SH | 1 |
| Iqbal, J | 1 |
| Mi, QY | 1 |
| Li, B | 1 |
| Wang, ZM | 1 |
| Mao, WX | 1 |
| Chen, SL | 1 |
| Wang, FM | 1 |
| Yang, YJ | 1 |
| Ma, LL | 1 |
| Tian, XJ | 1 |
| He, YQ | 1 |
| Ni, WJ | 1 |
| Ding, HH | 1 |
| Zhou, H | 1 |
| Qiu, YY | 1 |
| Tang, LQ | 1 |
| Pietra, D | 1 |
| Borghini, A | 1 |
| Bianucci, AM | 1 |
| Chang, W | 1 |
| Meng, Z | 1 |
| Yu, Y | 1 |
| Yao, F | 1 |
| Hatch, GM | 1 |
| Daskalopoulos, EP | 1 |
| Dufeys, C | 1 |
| Bertrand, L | 1 |
| Beauloye, C | 1 |
| Horman, S | 1 |
| Liu, X | 1 |
| Ye, L | 1 |
| Yuan, H | 1 |
| Yang, Z | 1 |
| Xiong, F | 1 |
| Chen, C | 1 |
| Liu, P | 2 |
| Huang, H | 2 |
| Lu, K | 1 |
| Shen, Y | 1 |
| He, J | 1 |
| Liu, G | 1 |
| Song, W | 1 |
| Liu, W | 1 |
| Shen, X | 1 |
| Lan, T | 1 |
| Li, W | 1 |
| Jiang, Q | 1 |
| Xie, X | 1 |
1 review available for berberine and Fibrosis
| Article | Year |
|---|---|
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracell | 2016 |
27 other studies available for berberine and Fibrosis
| Article | Year |
|---|---|
Evaluation of the effects of berberine in the prevention of epidural fibrosis in rats: An experimental research.
Topics: Animals; Berberine; Epidural Space; Fibrosis; Laminectomy; Rats; Rats, Wistar | 2022 |
Berberine protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition involving the inactivation of the NLRP3 inflammasome.
Topics: Animals; Berberine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glucose; Infl | 2022 |
Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts.
Topics: Berberine; Fibroblasts; Fibrosis; Graves Ophthalmopathy; Humans; Hyaluronic Acid; Inflammation; Orbi | 2022 |
Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats.
Topics: Actins; Animals; Berberine; Cisplatin; Dual Specificity Phosphatase 6; Fibrosis; Galectin 3; Kidney | 2022 |
Berberine Alleviates Doxorubicin-Induced Myocardial Injury and Fibrosis by Eliminating Oxidative Stress and Mitochondrial Damage via Promoting Nrf-2 Pathway Activation.
Topics: Animals; Apoptosis; Berberine; Cardiotoxicity; Doxorubicin; Fibrosis; Heart Injuries; Myocytes, Card | 2023 |
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Fatty Acids; Fibrosis; Inflammasomes; Inflammatio | 2023 |
Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats.
Topics: Animals; Berberine; Cardiomyopathies; Cell Transdifferentiation; Cells, Cultured; Coculture Techniqu | 2019 |
G-quadruplex ligands mediate downregulation of DUX4 expression.
Topics: Animals; Berberine; Cell Fusion; Cell Line, Tumor; Clone Cells; Down-Regulation; Enhancer Elements, | 2020 |
Berberine Attenuates Cardiac Hypertrophy Through Inhibition of mTOR Signaling Pathway.
Topics: Animals; Atrial Natriuretic Factor; Berberine; Cell Line; Disease Models, Animal; Fibrosis; Hypertro | 2020 |
Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization.
Topics: Actins; AMP-Activated Protein Kinase Kinases; Animals; Berberine; Ceruletide; Collagen Type I; Extra | 2020 |
Berberine hydrochloride inhibits inflammation and fibrosis after canalicular laceration repair in rabbits.
Topics: Animals; Anti-Inflammatory Agents; Berberine; Collagen; Cytokines; Fibrosis; Inflammation; Laceratio | 2020 |
Epiberberine ameliorated diabetic nephropathy by inactivating the angiotensinogen (Agt) to repress TGFβ/Smad2 pathway.
Topics: Angiotensinogen; Animals; Berberine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibros | 2021 |
Quercetin, Perillyl Alcohol, and Berberine Ameliorate Right Ventricular Disorders in Experimental Pulmonary Arterial Hypertension: Effects on miR-204, miR-27a, Fibrotic, Apoptotic, and Inflammatory Factors.
Topics: Animals; Antioxidants; Apoptosis; Berberine; Disease Models, Animal; Fibrosis; Hypertrophy, Right Ve | 2021 |
Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Chitosan; Diabetic Neph | 2021 |
Protective effect of berberine on renal fibrosis caused by diabetic nephropathy.
Topics: Actins; Animals; Berberine; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabet | 2017 |
Berberine alleviates adipose tissue fibrosis by inducing AMP-activated kinase signaling in high-fat diet-induced obese mice.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Berberine; Diet, H | 2018 |
Antifibrotic cardioprotection of berberine via downregulating myocardial IGF-1 receptor-regulated MMP-2/MMP-9 expression in diabetic rats.
Topics: Actins; Animals; Berberine; Blood Glucose; Cell Differentiation; Cell Proliferation; Cells, Cultured | 2018 |
Berberine ameliorates chronic kidney injury caused by atherosclerotic renovascular disease through the suppression of NFκB signaling pathway in rats.
Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Biomarkers; Fibrosis; Inflammation; Male; NF-kapp | 2013 |
Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy.
Topics: Animals; Arterial Pressure; Autophagy; Berberine; Blotting, Western; Body Weight; Cardiomegaly; Card | 2014 |
Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats.
Topics: Actins; Animals; Berberine; Biomarkers; Catalase; Cytoprotection; Disease Models, Animal; Fibrosis; | 2014 |
Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats.
Topics: Animals; Berberine; Blood Glucose; Blotting, Western; Collagen Type IV; Cytoprotection; Diabetes Mel | 2015 |
In vitro studies of antifibrotic and cytoprotective effects elicited by proto-berberine alkaloids in human dermal fibroblasts.
Topics: Berberine; Berberine Alkaloids; Cell Proliferation; Cells, Cultured; Collagen; Cytoprotection; Fibro | 2015 |
Berberine treatment prevents cardiac dysfunction and remodeling through activation of 5'-adenosine monophosphate-activated protein kinase in type 2 diabetic rats and in palmitate-induced hypertrophic H9c2 cells.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Cardiomegaly; Cell Line; Diabetes Mellitus, Type | 2015 |
Protective mechanisms of berberine against experimental autoimmune myocarditis in a rat model.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Berberine; Body Weight; Cytokines; Disease Models, Ani | 2016 |
Berberine attenuates high glucose-induced fibrosis by activating the G protein-coupled bile acid receptor TGR5 and repressing the S1P2/MAPK signaling pathway in glomerular mesangial cells.
Topics: Animals; Berberine; Cells, Cultured; Down-Regulation; Fibronectins; Fibrosis; Gene Knockdown Techniq | 2016 |
[Berberine inhibits cardiac fibrosis of diabetic rats].
Topics: Animals; Berberine; Collagen Type III; Connective Tissue Growth Factor; Diabetes Mellitus, Experimen | 2016 |
Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury.
Topics: Animals; Berberine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Down-Regulation; Extrac | 2010 |